PathWhiz

Pathway Description

Xylose Degradation I

Escherichia coli

Metabolic Pathway

Escherichia coli can utilize D-xylose as the sole source of carbon and energy for the cell. A low-affinity proton motive force or a high-affinity ATP-driven (ABC) transport system brings unphosphorylated D-xylose into the cell. Following entry, D-xylose is converted to D-xylulose by an isomerase and then converted to the pentose phosphate pathway intermediate, D-xylulose 5-phosphate via a kinase. D-xylulose 5-phosphate can then enter pathways of metabolism to meet the cells needs.

References

Xylose Degradation I References

Batt CA, Jamieson AC, Vandeyar MA: Identification of essential histidine residues in the active site of Escherichia coli xylose (glucose) isomerase. Proc Natl Acad Sci U S A. 1990 Jan;87(2):618-22.

Pubmed: 2405386

Highlighted elements will appear in red.

Highlight Compounds

	Adenosine diphosphate
	Adenosine triphosphate
	D-Xylulose
	Hydrogen Ion
	Xylulose 5-phosphate
	β-D-xylopyranose

Highlight Proteins

	D-xylose-proton symporter
	Xylose isomerase
	Xylulose kinase

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