PathWhiz

Pathway Description

Activation of cAMP-dependent protein kinase, PKA

Homo sapiens

Protein Pathway

cAMP dependent protein kinase is a signalling molecule, found in the nucleus and cytoplasm of cells. Cellular regulation and signal transduction in eukaryotic cells is driven by the phosphorylation of proteins. cAMP dependent protein kinase is created as an active enzyme, which is made possible by a fully phosphorylated activation loop.

References

Activation of cAMP-dependent protein kinase, PKA References

Cheng X, Ma Y, Moore M, Hemmings BA, Taylor SS: Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9849-54.

Pubmed: 9707564

Enter relative concentration values (without units). Elements will be highlighted in a color gradient where red = lowest concentration and green = highest concentration. For the best results, view the pathway in Black and White.

Visualize Compound Data

		Adenosine triphosphate
		cAMP
		Guanosine diphosphate
		Guanosine triphosphate
		Magnesium
		Phosphate
		Pyrophosphate

Visualize Protein Data

		Adenylate cyclase type 10
		cAMP-dependent protein kinase catalytic subunit alpha
		cAMP-dependent protein kinase catalytic subunit beta
		cAMP-dependent protein kinase catalytic subunit gamma
		cAMP-dependent protein kinase type I-alpha regulatory subunit
		cAMP-dependent protein kinase type I-beta regulatory subunit
		cAMP-dependent protein kinase type II-alpha regulatory subunit
		Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
		Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
		Guanine nucleotide-binding protein G(T) subunit gamma-T1
		Gβ

Clear

Downloads

SVG Image

Simple SVG Image

Large Font SVG Image

Simple Large Font SVG Image

Greyscale SVG Image

BioPAX

SBGN

SBML

PWML

PNG Image

All files (.zip)

Settings