GTP-
cyclohydrolase I
FOLic acid
synthesis
FOLic acid
synthesis
FOLic acid
synthesis
aminodeoxychorismate
lyase
Aminodeoxychorismate
synthase
FOLic acid
synthesis 3
dihydrofolate
reductase
glycinamide
ribotide
transformylase
mitochondrial C1-
tetrahydrofolate
synthase
Guanosine
triphosphate
H2O
Formic acid
H+
Dihydroneopterin
triphosphate
H2O
Dihydroneopterin
phosphate
PPi
H+
H2O
7,8-
Dihydroneopterin
Pi
Glycolaldehyde
6- hydroxymethyl-
7,8-
dihydropterin
ATP
AMP
H+
6- hydroxymethyl-
7,8-
dihydropterin
diphosphate
p-Aminobenzoic
acid
PPi
7,8-
Dihydropteroic
acid
4-amino-4-
deoxychorismate
H+
Pyruvic acid
Chorismate
L-Glutamine
L-Glutamic acid
ATP
L-Glutamic acid
ADP
Pi
H+
7,8-dihydrofolate
monoglutamate
H+
NADPH
NADP
Tetrahydrofolate
10-
Formyltetrahydrofolate
5'-
Phosphoribosyl-
N-
formylglycinamide
5'-
Phosphoribosyl-
N-
formylglycinamide
5,10-
Methenyltetrahydrofolic
acid
H2O
H+
Mitochondria