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Protein URA2 Protein URA2 Protein URA2 aspartate transcarbamylase Dihydroorotase Orotate phosphoribosyltransferase 2 orotidine-5'- phosphate decarboxylase UMP kinase nucleoside diphosphate kinase CTP synthase ribonucleoside diphosphate reductase 1 Ribonucleoside- diphosphate reductase large chain 1 nucleoside diphosphate kinase ribonucleoside diphosphate reductase 1 ribonucleoside diphosphate reductase 1 nucleoside diphosphate kinase deoxyuridine triphosphatase nucleoside triphosphate pyrophosphohydrolase pyrimidine deoxynucleoside triphosphate pyrophosphohydrolase nucleoside diphosphate kinase ribonucleoside- triphosphate reductase ribonucleoside- triphosphate reductase ribonucleoside- diphosphate reductase 2 ribonucleoside- diphosphate reductase 2 Ribonucleoside- diphosphate reductase large chain 1 Ribonucleoside- diphosphate reductase small chain 2 dCTP deaminase dihydroorotate dehydrogenase, type 2 Thymidylate synthase HCO 3 - H 2 O L-Glutamine ATP ADP P i L-Glutamic acid H + Carbamoyl phosphate L-Aspartic acid P i H + N-carbamoyl- L-aspartate H + H 2 O 4,5- Dihydroorotic acid Orotic acid Phosphoribosyl pyrophosphate PP i Orotidylic acid H + CO 2 Uridine 5'- monophosphate ATP ADP Uridine 5'-diphosphate ATP Uridine triphosphate ADP L-Glutamine H 2 O ATP ADP H + P i L-Glutamic acid Cytidine triphosphate H 2 O P i H + CDP H 2 O dCDP ATP ADP dCTP H 2 O dUDP ATP ADP Deoxyuridine triphosphate H 2 O P i H + dUMP ATP dTDP ADP Thymidine 5'-triphosphate H 2 O dCTP H 2 O Deoxyuridine triphosphate H 2 O dCDP H 2 O dUDP H 2 O H + Ammonium Deoxyuridine triphosphate Ubiquinone-1 Ubiquinol-1 Orotic acid 5,10- methenyltetrahydrofolate mono-L- glutamate Dihydrofolic acid 5-Thymidylic acid Adenosine triphosphate Zinc Magnesium Guanosine triphosphate Magnesium Magnesium Adenosine triphosphate Fe2+ Magnesium Magnesium Magnesium Zinc Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Fe3+ Flavin Mononucleotide reduced thioredoxin oxidized thioredoxin reduced thioredoxin oxidized thioredoxin a reduced flavodoxin an oxidized flavodoxin a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein L-Glutamate Metabolism PRPP Biosynthesis