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CHEBI:16015 ChEBI Aspartate kinase 30572 ChemSpider 1.0 17215925 ChemSpider 6022 PubChem-compound CHEBI:15961 ChEBI O-PHOSPHO-L-HOMOSERINE BioCyc 3702 TAXONOMY C23H38N7O17P3S Acetyl-CoA 809.1258 C4H4O5 Oxalacetic acid 132.00587 937 ChemSpider 22138-53-0 CAS Aspartokinase 1.0 NADH NADP-dependent glyceraldehyde-3-phosphate dehydrogenase SMILES N[C@@H](CCO)C(O)=O 439153 PubChem-compound 57 ChemSpider Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial SMILES O 50 ChemSpider 1.0 HMDB0003484 HMDB Adenosine triphosphate Q8RXU4 UniProt 809 ChemSpider C00441 KEGG Compound HMDB0000538 HMDB NAD 1.0 OXALACETIC_ACID BioCyc ATP BioCyc H4N Ammonium 18.034374 1.0 1.0 2.0 6816 PubChem-compound 328-42-7 CAS 51 PubChem-compound CHEBI:15846 ChEBI 2.7.2.4 false 2.7.2.4 Adenosine triphosphate + L-Aspartic acid → Adenosine diphosphate + L-Aspartyl-4-phosphate LEFT_TO_RIGHT 4.3.1.19 false 4.3.1.19 L-Threonine → (2Z)-2-aminobut-2-enoate + Hydrogen Ion + Water LEFT_TO_RIGHT ADP BioCyc 19796801 PubChem-compound 58 PubChem-compound 6288 PubChem-compound 53-59-8 CAS 1.0 Reaction2924 true 2-iminobutanoate + Hydrogen Ion + Water → 2-Ketobutyric acid + Ammonium LEFT_TO_RIGHT 5745 ChemSpider THR BioCyc 1.0 5742 ChemSpider 1038 PubChem-compound Water L-ASPARTATE BioCyc CHEBI:16474 ChEBI Acetaldehyde GO:0005829 GENE ONTOLOGY ReactionCatalysis7209 ACTIVATION GO:0009507 GENE ONTOLOGY C5H6O5 Oxoglutaric acid 146.02153 Reaction2923 true (2Z)-2-aminobut-2-enoate → 2-iminobutanoate LEFT_TO_RIGHT 1.0 CHEBI:16908 ChEBI C4H10NO6P O-Phosphohomoserine 199.02457 Aspartokinase 1, chloroplastic Aspartokinase 2, chloroplastic threonine deaminase C00109 KEGG Compound O4P Phosphate 94.95342 Acetyl-CoA NADPH 945 ChemSpider P10869 UniProt SMILES CC=C(N)C([O-])=O 1010 ChemSpider 1.0 Oxoglutaric acid SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS Q8S7B5 UniProt NADP 600-18-0 CAS C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 Mitochondrion Aspartate semialdehyde dehydrogenase 1.0 1.0 NADPH BioCyc GLY BioCyc Hydrogen Ion CHEBI:16857 ChEBI HMDB0000208 HMDB 672-15-1 CAS Cytosol Probable low-specificity L-threonine aldolase 1 218 ChemSpider Adenosine triphosphate 58-68-4 CAS 72-19-5 CAS HMDB0001423 HMDB 4210-66-6 CAS SMILES [O-]P([O-])([O-])=O HMDB0000217 HMDB SMILES OC(=O)CCC(=O)C(O)=O CHEBI:30915 ChEBI C2H5NO2 Glycine 75.03203 Q8L7R2 UniProt 1.0 L-Aspartate-semialdehyde C00009 KEGG Compound C00008 KEGG Compound ReactionCatalysis7194 ACTIVATION 1.0 Q8VYI4 UniProt C00006 KEGG Compound SMILES N[C@@H](CCOP(O)(O)=O)C(O)=O Aspartokinase 2, chloroplastic Reaction7271 false Hydrogen Ion + L-Aspartyl-4-phosphate + NADPH → L-Aspartate-semialdehyde + NADP + Phosphate LEFT_TO_RIGHT Q0WM29 UniProt Aspartokinase 1, chloroplastic CHEBI:18009 ChEBI HMDB0001429 HMDB C00001 KEGG Compound C00005 KEGG Compound CHEBI:18367 ChEBI C00004 KEGG Compound 1032 ChemSpider C00003 KEGG Compound 2-OXOBUTANOATE BioCyc C00002 KEGG Compound C4H6NO2 (2Z)-2-aminobut-2-enoate 100.040405 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O L-Glutamic acid HMDB0000221 HMDB 6051 ChemSpider 5257127 PubChem-compound HMDB0000223 HMDB C03082 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O ReactionCatalysis6301 ACTIVATION Adenosine diphosphate GLT BioCyc 53-57-6 CAS Q9ZSS6 UniProt C21H28N7O14P2 NAD 664.11694 C4H6NO2 2-iminobutanoate 100.040405 44367445 PubChem-compound 1.0 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial C01342 KEGG Compound C00010 KEGG Compound CHEBI:28938 ChEBI HMDB0000902 HMDB NADP-dependent glyceraldehyde-3-phosphate dehydrogenase SMILES C[C@@H](O)[C@H](N)C(O)=O C01102 KEGG Compound 1.0 NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 Glycine 5957 PubChem-compound HMDB0001206 HMDB 2.6.1.1 false 2.6.1.1 L-Glutamic acid + Oxalacetic acid ↔ L-Aspartic acid + Oxoglutaric acid REVERSIBLE 12126 ChemSpider H Hydrogen Ion 1.007825 2.7.1.39 false 2.7.1.39 Adenosine triphosphate + L-Homoserine → Adenosine diphosphate + Hydrogen Ion + O-Phosphohomoserine LEFT_TO_RIGHT C00263 KEGG Compound 56-65-5 CAS 53-84-9 CAS 4.0 C00026 KEGG Compound C00025 KEGG Compound 1.0 C00024 KEGG Compound Aspartate aminotransferase 3, chloroplastic Threonine Metabolism HMDB0000123 HMDB Adenosine diphosphate L-Aspartic acid GO:0005739 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 chloroplast HMDB0000005 HMDB SMILES CCC(=O)C(O)=O SMILES N[C@@H](CC(O)=O)C(O)=O NADPH SMILES N[C@@H](CC=O)C(O)=O SMILES NC(CC(=O)OP(O)(O)=O)C(O)=O 1.0 Threonine dehydratase biosynthetic, chloroplastic Oxalacetic acid 1.0 1.0 Homoserine kinase 2.0 CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 1.0 C00037 KEGG Compound C00036 KEGG Compound 5682 ChemSpider L-Homoserine SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 328-50-7 CAS CHEBI:30831 ChEBI CHEBI:1146900 ChEBI (2Z)-2-aminobut-2-enoate Aspartokinase ReactionCatalysis7266 ACTIVATION HMDB0001341 HMDB 1.0 HMDB0012249 HMDB CHEBI:15699 ChEBI CO-A BioCyc Threonine synthase 1, chloroplastic Probable low-specificity L-threonine aldolase 1 5675 ChemSpider 72-89-9 CAS C00049 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 L-Homoserine HMDB0000148 HMDB 14798-03-9 CAS P46644 UniProt CHEBI:58739 ChEBI 1.0 Threonine dehydratase biosynthetic, chloroplastic CHEBI:15422 ChEBI Aspartate semialdehyde dehydrogenase Threonine synthase 1, chloroplastic ReactionCatalysis7165 ACTIVATION 6557 ChemSpider 12647 PubChem-compound Arabidopsis thaliana HMDB0012250 HMDB SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N SMILES OC(=O)CC(=O)C(O)=O 388299 ChemSpider 7732-18-5 CAS 1.0 2-iminobutanoate 1.0 HMDB0001487 HMDB L-BETA-ASPARTYL-P BioCyc 1.0 56-86-0 CAS 1.0 SMP0002444 SMPDB 4.0 C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound ReactionCatalysis7293 ACTIVATION SMILES [NH4+] ReactionCatalysis7292 ACTIVATION ReactionCatalysis7291 ACTIVATION C10H16N5O13P3 Adenosine triphosphate 506.99576 aspartate kinase / homoserine dehydrogenase 1.0 C00188 KEGG Compound CHEBI:17053 ChEBI 56-40-6 CAS Acetaldehyde 1.0 ReactionCatalysis7290 ACTIVATION CHEBI:16761 ChEBI HMDB0000719 HMDB Q9LYU8 UniProt HMDB0000167 HMDB 1.0 C2H4O Acetaldehyde 44.026215 Q1WIQ6 UniProt CHEBI:15428 ChEBI 1.0 133252 ChemSpider 962 PubChem-compound 151187 PubChem-compound C4H9NO3 L-Threonine 119.05824 O-Phosphohomoserine 2-KETOGLUTARATE BioCyc 5800 ChemSpider 392413 ChemSpider SMILES CCC(=N)C([O-])=O Phosphate Phosphate 1.0 5893 PubChem-compound 439235 PubChem-compound C00080 KEGG Compound 730 ChemSpider 4.2.3.1 false 4.2.3.1 O-Phosphohomoserine + Water → L-Threonine + Phosphate LEFT_TO_RIGHT L-Aspartyl-4-phosphate 2.7.2.4 false 2.7.2.4 Hydrogen Ion + L-Aspartate-semialdehyde + NADPH → L-Homoserine + NADP LEFT_TO_RIGHT C00084 KEGG Compound 75-07-0 CAS 172 ChemSpider 15106-57-7 CAS SMILES N[C@@H](CCC(O)=O)C(O)=O HMDB0002111 HMDB CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS O23653 UniProt 832 PubChem-compound PW002554 PathWhiz ACETALD BioCyc 58-64-0 CAS Acetaldehyde SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Ammonium 5886 PubChem-compound O-Phosphohomoserine C4H8NO7P L-Aspartyl-4-phosphate 213.00385 1.0 SMILES CC=O L-Aspartate-semialdehyde L-Aspartyl-4-phosphate CHEBI:30744 ChEBI C4H6O3 2-Ketobutyric acid 102.03169 C4H7NO4 L-Aspartic acid 133.0375 C4H7NO3 L-Aspartate-semialdehyde 117.042595 1.0 Homoserine kinase Aspartate aminotransferase 3, chloroplastic 1.0 CHEBI:15343 ChEBI 1.0 444493 PubChem-compound 16741146 PubChem-compound 388372 ChemSpider 1.0 1.0 L-ASPARTATE-SEMIALDEHYDE BioCyc 22833512 PubChem-compound HOMO-SER BioCyc ACETYL-COA BioCyc NADP CHEBI:18051 ChEBI H2O Water 18.010565 SMILES NCC(O)=O HMDB0000191 HMDB 2-Ketobutyric acid NADH BioCyc C4H9NO3 L-Homoserine 119.05824 HMDB0000990 HMDB NAD BioCyc 1061 PubChem-compound HMDB0059597 HMDB HMDB0041827 HMDB ReactionCatalysis7252 ACTIVATION Transport580 false Acetaldehyde (→) Transport: Arabidopsis thaliana, Cytosol to Arabidopsis thaliana, Cell, Mitochondrion LEFT_TO_RIGHT 1.0 56-84-8 CAS L-Threonine 177 PubChem-compound CHEBI:15351 ChEBI 970 PubChem-compound L-Threonine 4.1.2.48 false 4.1.2.48 L-Threonine → Acetaldehyde + Glycine LEFT_TO_RIGHT 1.2.1.4 false 1.2.1.4 Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT 85-61-0 CAS Hydrogen Ion Reaction7321 false Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT Aspartate semialdehyde dehydrogenase Homoserine kinase Probable low-specificity L-threonine aldolase 1 Methylmalonate- semialdehyde dehydrogenase [acylating], mitochondrial NADP-dependent glyceraldehyde- 3-phosphate dehydrogenase Aspartokinase Aspartate aminotransferase 3, chloroplastic Aspartokinase 1, chloroplastic Aspartokinase 2, chloroplastic Threonine synthase 1, chloroplastic Threonine dehydratase biosynthetic, chloroplastic Acetaldehyde Acetaldehyde L-Aspartyl-4- phosphate NADPH H + P i NADP L-Aspartate- semialdehyde L-Homoserine ATP ADP H + O- Phosphohomoserine L-Threonine Glycine NAD CoA NADH H + Acetyl-CoA CoA NAD NADH H + Acetyl-CoA L-Aspartic acid ATP ADP L-Aspartyl-4- phosphate Oxalacetic acid L-Glutamic acid Oxoglutaric acid H + NADPH NADP L-Homoserine H 2 O P i L-Threonine H + H 2 O (2Z)-2- aminobut-2- enoate 2- iminobutanoate H 2 O H + Ammonium 2-Ketobutyric acid
CHEBI:16015 ChEBI Aspartate kinase 30572 ChemSpider 1.0 17215925 ChemSpider 6022 PubChem-compound CHEBI:15961 ChEBI O-PHOSPHO-L-HOMOSERINE BioCyc 3702 TAXONOMY C23H38N7O17P3S Acetyl-CoA 809.1258 C4H4O5 Oxalacetic acid 132.00587 937 ChemSpider 22138-53-0 CAS Aspartokinase 1.0 NADH NADP-dependent glyceraldehyde-3-phosphate dehydrogenase SMILES N[C@@H](CCO)C(O)=O 439153 PubChem-compound 57 ChemSpider Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial SMILES O 50 ChemSpider 1.0 HMDB0003484 HMDB Adenosine triphosphate Q8RXU4 UniProt 809 ChemSpider C00441 KEGG Compound HMDB0000538 HMDB NAD 1.0 OXALACETIC_ACID BioCyc ATP BioCyc H4N Ammonium 18.034374 1.0 1.0 2.0 6816 PubChem-compound 328-42-7 CAS 51 PubChem-compound CHEBI:15846 ChEBI 2.7.2.4 false 2.7.2.4 Adenosine triphosphate + L-Aspartic acid → Adenosine diphosphate + L-Aspartyl-4-phosphate LEFT_TO_RIGHT 4.3.1.19 false 4.3.1.19 L-Threonine → (2Z)-2-aminobut-2-enoate + Hydrogen Ion + Water LEFT_TO_RIGHT ADP BioCyc 19796801 PubChem-compound 58 PubChem-compound 6288 PubChem-compound 53-59-8 CAS 1.0 Reaction2924 true 2-iminobutanoate + Hydrogen Ion + Water → 2-Ketobutyric acid + Ammonium LEFT_TO_RIGHT 5745 ChemSpider THR BioCyc 1.0 5742 ChemSpider 1038 PubChem-compound Water L-ASPARTATE BioCyc CHEBI:16474 ChEBI Acetaldehyde GO:0005829 GENE ONTOLOGY ReactionCatalysis7209 ACTIVATION GO:0009507 GENE ONTOLOGY C5H6O5 Oxoglutaric acid 146.02153 Reaction2923 true (2Z)-2-aminobut-2-enoate → 2-iminobutanoate LEFT_TO_RIGHT 1.0 CHEBI:16908 ChEBI C4H10NO6P O-Phosphohomoserine 199.02457 Aspartokinase 1, chloroplastic Aspartokinase 2, chloroplastic threonine deaminase C00109 KEGG Compound O4P Phosphate 94.95342 Acetyl-CoA NADPH 945 ChemSpider P10869 UniProt SMILES CC=C(N)C([O-])=O 1010 ChemSpider 1.0 Oxoglutaric acid SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS Q8S7B5 UniProt NADP 600-18-0 CAS C21H30N7O17P3 NADPH 745.0911 C21H29N7O17P3 NADP 744.08325 Mitochondrion Aspartate semialdehyde dehydrogenase 1.0 1.0 NADPH BioCyc GLY BioCyc Hydrogen Ion CHEBI:16857 ChEBI HMDB0000208 HMDB 672-15-1 CAS Cytosol Probable low-specificity L-threonine aldolase 1 218 ChemSpider Adenosine triphosphate 58-68-4 CAS 72-19-5 CAS HMDB0001423 HMDB 4210-66-6 CAS SMILES [O-]P([O-])([O-])=O HMDB0000217 HMDB SMILES OC(=O)CCC(=O)C(O)=O CHEBI:30915 ChEBI C2H5NO2 Glycine 75.03203 Q8L7R2 UniProt 1.0 L-Aspartate-semialdehyde C00009 KEGG Compound C00008 KEGG Compound ReactionCatalysis7194 ACTIVATION 1.0 Q8VYI4 UniProt C00006 KEGG Compound SMILES N[C@@H](CCOP(O)(O)=O)C(O)=O Aspartokinase 2, chloroplastic Reaction7271 false Hydrogen Ion + L-Aspartyl-4-phosphate + NADPH → L-Aspartate-semialdehyde + NADP + Phosphate LEFT_TO_RIGHT Q0WM29 UniProt Aspartokinase 1, chloroplastic CHEBI:18009 ChEBI HMDB0001429 HMDB C00001 KEGG Compound C00005 KEGG Compound CHEBI:18367 ChEBI C00004 KEGG Compound 1032 ChemSpider C00003 KEGG Compound 2-OXOBUTANOATE BioCyc C00002 KEGG Compound C4H6NO2 (2Z)-2-aminobut-2-enoate 100.040405 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O L-Glutamic acid HMDB0000221 HMDB 6051 ChemSpider 5257127 PubChem-compound HMDB0000223 HMDB C03082 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O ReactionCatalysis6301 ACTIVATION Adenosine diphosphate GLT BioCyc 53-57-6 CAS Q9ZSS6 UniProt C21H28N7O14P2 NAD 664.11694 C4H6NO2 2-iminobutanoate 100.040405 44367445 PubChem-compound 1.0 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial C01342 KEGG Compound C00010 KEGG Compound CHEBI:28938 ChEBI HMDB0000902 HMDB NADP-dependent glyceraldehyde-3-phosphate dehydrogenase SMILES C[C@@H](O)[C@H](N)C(O)=O C01102 KEGG Compound 1.0 NAD(P) BioCyc C21H29N7O14P2 NADH 665.12476 Glycine 5957 PubChem-compound HMDB0001206 HMDB 2.6.1.1 false 2.6.1.1 L-Glutamic acid + Oxalacetic acid ↔ L-Aspartic acid + Oxoglutaric acid REVERSIBLE 12126 ChemSpider H Hydrogen Ion 1.007825 2.7.1.39 false 2.7.1.39 Adenosine triphosphate + L-Homoserine → Adenosine diphosphate + Hydrogen Ion + O-Phosphohomoserine LEFT_TO_RIGHT C00263 KEGG Compound 56-65-5 CAS 53-84-9 CAS 4.0 C00026 KEGG Compound C00025 KEGG Compound 1.0 C00024 KEGG Compound Aspartate aminotransferase 3, chloroplastic Threonine Metabolism HMDB0000123 HMDB Adenosine diphosphate L-Aspartic acid GO:0005739 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 chloroplast HMDB0000005 HMDB SMILES CCC(=O)C(O)=O SMILES N[C@@H](CC(O)=O)C(O)=O NADPH SMILES N[C@@H](CC=O)C(O)=O SMILES NC(CC(=O)OP(O)(O)=O)C(O)=O 1.0 Threonine dehydratase biosynthetic, chloroplastic Oxalacetic acid 1.0 1.0 Homoserine kinase 2.0 CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 1.0 C00037 KEGG Compound C00036 KEGG Compound 5682 ChemSpider L-Homoserine SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 328-50-7 CAS CHEBI:30831 ChEBI CHEBI:1146900 ChEBI (2Z)-2-aminobut-2-enoate Aspartokinase ReactionCatalysis7266 ACTIVATION HMDB0001341 HMDB 1.0 HMDB0012249 HMDB CHEBI:15699 ChEBI CO-A BioCyc Threonine synthase 1, chloroplastic Probable low-specificity L-threonine aldolase 1 5675 ChemSpider 72-89-9 CAS C00049 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 L-Homoserine HMDB0000148 HMDB 14798-03-9 CAS P46644 UniProt CHEBI:58739 ChEBI 1.0 Threonine dehydratase biosynthetic, chloroplastic CHEBI:15422 ChEBI Aspartate semialdehyde dehydrogenase Threonine synthase 1, chloroplastic ReactionCatalysis7165 ACTIVATION 6557 ChemSpider 12647 PubChem-compound Arabidopsis thaliana HMDB0012250 HMDB SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N SMILES OC(=O)CC(=O)C(O)=O 388299 ChemSpider 7732-18-5 CAS 1.0 2-iminobutanoate 1.0 HMDB0001487 HMDB L-BETA-ASPARTYL-P BioCyc 1.0 56-86-0 CAS 1.0 SMP0002444 SMPDB 4.0 C5H9NO4 L-Glutamic acid 147.05316 33032 PubChem-compound ReactionCatalysis7293 ACTIVATION SMILES [NH4+] ReactionCatalysis7292 ACTIVATION ReactionCatalysis7291 ACTIVATION C10H16N5O13P3 Adenosine triphosphate 506.99576 aspartate kinase / homoserine dehydrogenase 1.0 C00188 KEGG Compound CHEBI:17053 ChEBI 56-40-6 CAS Acetaldehyde 1.0 ReactionCatalysis7290 ACTIVATION CHEBI:16761 ChEBI HMDB0000719 HMDB Q9LYU8 UniProt HMDB0000167 HMDB 1.0 C2H4O Acetaldehyde 44.026215 Q1WIQ6 UniProt CHEBI:15428 ChEBI 1.0 133252 ChemSpider 962 PubChem-compound 151187 PubChem-compound C4H9NO3 L-Threonine 119.05824 O-Phosphohomoserine 2-KETOGLUTARATE BioCyc 5800 ChemSpider 392413 ChemSpider SMILES CCC(=N)C([O-])=O Phosphate Phosphate 1.0 5893 PubChem-compound 439235 PubChem-compound C00080 KEGG Compound 730 ChemSpider 4.2.3.1 false 4.2.3.1 O-Phosphohomoserine + Water → L-Threonine + Phosphate LEFT_TO_RIGHT L-Aspartyl-4-phosphate 2.7.2.4 false 2.7.2.4 Hydrogen Ion + L-Aspartate-semialdehyde + NADPH → L-Homoserine + NADP LEFT_TO_RIGHT C00084 KEGG Compound 75-07-0 CAS 172 ChemSpider 15106-57-7 CAS SMILES N[C@@H](CCC(O)=O)C(O)=O HMDB0002111 HMDB CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] 14265-44-2 CAS O23653 UniProt 832 PubChem-compound PW002554 PathWhiz ACETALD BioCyc 58-64-0 CAS Acetaldehyde SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Ammonium 5886 PubChem-compound O-Phosphohomoserine C4H8NO7P L-Aspartyl-4-phosphate 213.00385 1.0 SMILES CC=O L-Aspartate-semialdehyde L-Aspartyl-4-phosphate CHEBI:30744 ChEBI C4H6O3 2-Ketobutyric acid 102.03169 C4H7NO4 L-Aspartic acid 133.0375 C4H7NO3 L-Aspartate-semialdehyde 117.042595 1.0 Homoserine kinase Aspartate aminotransferase 3, chloroplastic 1.0 CHEBI:15343 ChEBI 1.0 444493 PubChem-compound 16741146 PubChem-compound 388372 ChemSpider 1.0 1.0 L-ASPARTATE-SEMIALDEHYDE BioCyc 22833512 PubChem-compound HOMO-SER BioCyc ACETYL-COA BioCyc NADP CHEBI:18051 ChEBI H2O Water 18.010565 SMILES NCC(O)=O HMDB0000191 HMDB 2-Ketobutyric acid NADH BioCyc C4H9NO3 L-Homoserine 119.05824 HMDB0000990 HMDB NAD BioCyc 1061 PubChem-compound HMDB0059597 HMDB HMDB0041827 HMDB ReactionCatalysis7252 ACTIVATION Transport580 false Acetaldehyde (→) Transport: Arabidopsis thaliana, Cytosol to Arabidopsis thaliana, Cell, Mitochondrion LEFT_TO_RIGHT 1.0 56-84-8 CAS L-Threonine 177 PubChem-compound CHEBI:15351 ChEBI 970 PubChem-compound L-Threonine 4.1.2.48 false 4.1.2.48 L-Threonine → Acetaldehyde + Glycine LEFT_TO_RIGHT 1.2.1.4 false 1.2.1.4 Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT 85-61-0 CAS Hydrogen Ion Reaction7321 false Acetaldehyde + Coenzyme A + NAD → Acetyl-CoA + Hydrogen Ion + NADH LEFT_TO_RIGHT Mitochondria Unknown Unknown THA1 ALDH6B2 ALDH11A3 HOM3 ASP3 AK1 AK2 TS1 OMR1 Acetaldehyde Acetaldehyde L-Aspartyl-4- phosphate NADPH Hydrogen Ion Phosphate NADP L-Aspartate- semialdehyde L-Homoserine Adenosine triphosphate Adenosine diphosphate