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Malate dehydrogenase, mitochondrial Malate dehydrogenase, mitochondrial Serine/threonine- protein kinase mTOR Unknown Myc proto-oncogene protein Mitochondrial pyruvate carrier 1 Mitochondrial pyruvate carrier 1 Neutral amino acid transporter B(0) Neutral amino acid transporter A Unknown Unknown Monocarboxylate transporter 1 Unknown Pyruvate dehydrogenase complex Citrate synthase, mitochondrial Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial Oxoglutarate dehydrogenase complex Succinyl-CoA ligase Fumarate hydratase, mitochondrial Pyruvate carboxylase, mitochondrial Aconitate hydratase, mitochondrial Aconitate hydratase, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Pyruvate dehydrogenase complex Citrate synthase, mitochondrial Fumarate hydratase, mitochondrial Pyruvate carboxylase, mitochondrial Aconitate hydratase, mitochondrial Aconitate hydratase, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Glutaminase liver isoform, mitochondrial Glutamate dehydrogenase 1, mitochondrial Aspartate aminotransferase, mitochondrial Unknown Unknown NADP-dependent malic enzyme Unknown Unknown ATP-citrate synthase ATP-citrate synthase Pyruvic acid FADH2 Pyruvic acid FADH2 Pyruvic acid Pyruvic acid L-Glutamine L-Glutamine L-Glutamine L-Glutamine L-Lactic acid L-Lactic acid L-Glutamine L-Glutamine L-Leucine L-Leucine CoA NAD Acetyl-CoA CO2 NADH H2O Oxalacetic acid Citric acid CoA Isocitric acid NAD Oxoglutaric acid CO2 NADH H+ NAD CoA Succinyl-CoA NADH H+ CO2 Pi GDP CoA GTP L-Malic acid Fumaric acid H2O NAD NADH H+ ATP HCO3- ADP Pi cis-Aconitic acid H2O H2O Q FAD FADH2 Fumaric acid QH2 CoA NAD Acetyl-CoA CO2 NADH H2O Oxalacetic acid Citric acid CoA L-Malic acid Fumaric acid H2O NAD NADH H+ ATP HCO3- ADP Pi cis-Aconitic acid H2O H2O Isocitric acid Q FAD FADH2 Fumaric acid QH2 L-Glutamic acid NH3 NAD NADH Hydrogen ion Oxoglutaric acid Oxalacetic acid Oxoglutaric acid L-Aspartic acid Pyruvic acid Oxoglutaric acid L-Alanine NADP NADPH H+ CO2 Pyruvic acid NADH H+ NAD CO2 Citric acid CoA ATP Oxalacetic acid ADP Acetyl-CoA CoA ATP Oxalacetic acid ADP Acetyl-CoA Oxygen L-Glutamine Thiamine pyrophosphate Lipoamide FAD Magnesium Thiamine pyrophosphate Lipoamide FAD Biotin Manganese 4Fe-4S 4Fe-4S Thiamine pyrophosphate Lipoamide FAD Biotin Manganese 4Fe-4S 4Fe-4S Pyridoxal 5'-phosphate Manganese 4Fe-4S Aconitate hydratase, mitochondrial Glycolysis Mitochondrial Electron Transport Chain Glycolysis Mitochondrial Electron Transport Chain Succinic acid Inner mitochondrial membrane Mitochondrial intermembrane space Cytosol Mitochondrial matrix Mitochondrion Intracellular Space Inner mitochondrial membrane Outer mitochondrial membrane Inner mitochondrial membrane Mitochondrial intermembrane space Cytosol Mitochondrial matrix Mitochondrion Intracellular Space Inner mitochondrial membrane Outer mitochondrial membrane Pseudo-Hypoxia Mutant Aconitase Mutant Aconitase Lipid Synthesis
Mitochondria Mitochondria Mdh2 Mdh2 Mtor Unknown Myc Mpc1 Mpc1 Slc1a5 Slc1a4 Unknown Unknown Slc16a1 Unknown Pdha1 Cs Idh3a Idh3g Idh3g Ogdh Suclg1 Suclg2 Fh Pc Aco2 Aco2 Sdhd Sdhc Sdhb Sdha Pdha1 Cs Fh Pc Aco2 Aco2 Sdhd Sdhc Sdhb Sdha Gls2 Glud1 Got2 Unknown Unknown Me1 Unknown Unknown Acly Acly Pyruvic acid FADH Pyruvic acid FADH Pyruvic acid Pyruvic acid L-Glutamine L-Glutamine L-Glutamine L-Glutamine L-Lactic acid L-Lactic acid L-Glutamine L-Glutamine L-Leucine L-Leucine Coenzyme A NAD Acetyl-CoA Carbon dioxide NADH Water Oxalacetic acid Citric acid Coenzyme A Isocitric acid NAD Oxoglutaric acid Carbon dioxide NADH Hydrogen Ion NAD Coenzyme A Succinyl-CoA NADH Hydrogen Ion Carbon dioxide Phosphate Guanosine diphosphate Coenzyme A Guanosine triphosphate L-Malic acid Fumaric acid Water NAD NADH Hydrogen Ion Adenosine triphosphate Hydrogen carbonate Adenosine diphosphate Phosphate cis-Aconitic acid Water Water Coenzyme Q10 FAD FADH Fumaric acid QH2 Coenzyme A NAD Acetyl-CoA Carbon dioxide NADH Water Oxalacetic acid Citric acid Coenzyme A L-Malic acid Fumaric acid Water NAD NADH Hydrogen Ion Adenosine triphosphate Hydrogen carbonate Adenosine diphosphate Phosphate cis-Aconitic acid Water Water Isocitric acid Coenzyme Q10 FAD FADH Fumaric acid QH2 L-Glutamic acid Ammonia NAD NADH Hydrogen ion Oxoglutaric acid Oxalacetic acid Oxoglutaric acid L-Aspartic acid Pyruvic acid Oxoglutaric acid L-Alanine NADP NADPH Hydrogen Ion Carbon dioxide Pyruvic acid NADH Hydrogen Ion NAD Carbon dioxide Citric acid Coenzyme A Adenosine triphosphate Oxalacetic acid Adenosine diphosphate Acetyl-CoA Coenzyme A Adenosine triphosphate Oxalacetic acid Adenosine diphosphate Acetyl-CoA Oxygen L-Glutamine Aco2 Glycolysis Mitochondrial Electron Transport Chain Glycolysis Mitochondrial Electron Transport Chain Succinic acid
Mdh2 Mdh2 Mtor Myc Mpc1 Mpc1 Slc1a5 Slc1a4 Slc16a1 Pdha1 Cs Idh3a Idh3g Idh3g Ogdh Suclg1 Suclg2 Fh Pc Aco2 Aco2 Sdhd Sdhc Sdhb Sdha Pdha1 Cs Fh Pc Aco2 Aco2 Sdhd Sdhc Sdhb Sdha Gls2 Glud1 Got2 Me1 Acly Acly Pyr FADH2 Pyr FADH2 Pyr Pyr Gln Gln Gln Gln Lactate Lactate Gln Gln Leu Leu CoA NAD Ac-CoA CO2 NADH H2O Oaa CA CoA I-cita NAD AKG CO2 NADH H+ NAD CoA Suc-CoA NADH H+ CO2 Pi GDP CoA GTP Malate Fumarat H2O NAD NADH H+ ATP HCO3- ADP Pi Aconiti H2O H2O Q FAD FADH2 Fumarat QH2 CoA NAD Ac-CoA CO2 NADH H2O Oaa CA CoA Malate Fumarat H2O NAD NADH H+ ATP HCO3- ADP Pi Aconiti H2O H2O I-cita Q FAD FADH2 Fumarat QH2 Glu NH3 NAD NADH HI AKG Oaa AKG Asp Pyr AKG Ala NADP NADPH H+ CO2 Pyr NADH H+ NAD CO2 CA CoA ATP Oaa ADP Ac-CoA CoA ATP Oaa ADP Ac-CoA O2 Gln ThiamPP Lipoamd FAD Mg2+ ThiamPP Lipoamd FAD Biotin Mn2+ 4Fe-4S 4Fe-4S ThiamPP Lipoamd FAD Biotin Mn2+ 4Fe-4S 4Fe-4S Pyr-5'P Mn2+ 4Fe-4S Aco2 PW000146 PW000165 PW000146 PW000165 Succini Inner mitochondrial membrane Mitochondrial intermembrane space Cytosol Mitochondrial matrix Mitochondrion Intracellular Space Inner mitochondrial membrane Outer mitochondrial membrane Inner mitochondrial membrane Mitochondrial intermembrane space Cytosol Mitochondrial matrix Mitochondrion Intracellular Space Inner mitochondrial membrane Outer mitochondrial membrane Pseudo-Hypoxia Mutant Aconitase Mutant Aconitase Lipid Synthesis
Mitochondria Mitochondria Mdh2 Mdh2 Mtor Myc Mpc1 Mpc1 Slc1a5 Slc1a4 Slc16a1 Pdha1 Cs Idh3a Idh3g Idh3g Ogdh Suclg1 Suclg2 Fh Pc Aco2 Aco2 Sdhd Sdhc Sdhb Sdha Pdha1 Cs Fh Pc Aco2 Aco2 Sdhd Sdhc Sdhb Sdha Gls2 Glud1 Got2 Me1 Acly Acly Pyr FADH Pyr FADH Pyr Pyr Gln Gln Gln Gln Lactate Lactate Gln Gln Leu Leu CoA NAD Ac-CoA CO2 NADH H2O Oaa CA CoA I-cita NAD AKG CO2 NADH H+ NAD CoA Suc-CoA NADH H+ CO2 Pi GDP CoA GTP Malate Fumarat H2O NAD NADH H+ ATP HCO3 ADP Pi Aconiti H2O H2O Coq FAD FADH Fumarat QH2 CoA NAD Ac-CoA CO2 NADH H2O Oaa CA CoA Malate Fumarat H2O NAD NADH H+ ATP HCO3 ADP Pi Aconiti H2O H2O I-cita Coq FAD FADH Fumarat QH2 Glu NH3 NAD NADH HI AKG Oaa AKG Asp Pyr AKG Ala NADP NADPH H+ CO2 Pyr NADH H+ NAD CO2 CA CoA ATP Oaa ADP Ac-CoA CoA ATP Oaa ADP Ac-CoA O2 Gln Aco2 PW000146 PW000165 PW000146 PW000165 Succini