Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/KEGG Compound C00437
type: UnificationXref
id: C00437
db: KEGG Compound

Reference/PubChem-compound 439161
type: UnificationXref
id: 439161
db: PubChem-compound

Reference/UniProt P04391
type: UnificationXref
id: P04391
db: UniProt

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

4-Aminobutyraldehyde
type: SmallMolecule
entity reference: 4-Aminobutyraldehyde

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

Compound/PW C000036/Stoichiometry/1.0
type: Stoichiometry
physical entity: Argininosuccinic acid
stoichiometric coefficient: 1.0

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Reference/ChEBI CHEBI 16265
type: UnificationXref
id: CHEBI:16265
db: ChEBI

Reaction2694
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000029/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000140/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001856/Stoichiometry/1.0
right: Ornithine
right: Acetic acid
spontaneous: false
left: Water
left: N-Acetylornithine
name: N-Acetylornithine + Water → Acetic acid + Ornithine
conversion direction: LEFT_TO_RIGHT

1.2.1.79
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000174 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000972 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/2.0
right: Hydrogen Ion
right: Succinic acid
right: NADPH
spontaneous: false
EC number: 1.2.1.79
left: NADP
left: Succinic acid semialdehyde
left: Water
name: NADP + Succinic acid semialdehyde + Water → 2 Hydrogen Ion + NADPH + Succinic acid
conversion direction: LEFT_TO_RIGHT

1.2.1.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000972/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000174/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/2.0
right: Succinic acid
right: NADH
right: Hydrogen Ion
spontaneous: false
EC number: 1.2.1.16
left: Water
left: NAD
left: Succinic acid semialdehyde
name: NAD + Succinic acid semialdehyde + Water → 2 Hydrogen Ion + NADH + Succinic acid
conversion direction: LEFT_TO_RIGHT

1.2.1.19
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000071/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000849/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADH
right: Hydrogen Ion
right: γ-Aminobutyric acid
spontaneous: false
EC number: 1.2.1.19
left: 4-Aminobutyraldehyde
left: Water
left: NAD
name: 4-Aminobutyraldehyde + NAD + Water → Hydrogen Ion + NADH + γ-Aminobutyric acid
conversion direction: LEFT_TO_RIGHT

2.6.1.19
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000972/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000071/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: L-Glutamic acid
right: Succinic acid semialdehyde
spontaneous: false
EC number: 2.6.1.19
left: Oxoglutaric acid
left: γ-Aminobutyric acid
name: Oxoglutaric acid + γ-Aminobutyric acid → L-Glutamic acid + Succinic acid semialdehyde
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/UniProt P23908
type: UnificationXref
id: P23908
db: UniProt

Compound/PW C000934/Stoichiometry/1.0
type: Stoichiometry
physical entity: N2-Succinyl-L-ornithine
stoichiometric coefficient: 1.0

Reference/ChemSpider 5746
type: UnificationXref
id: 5746
db: ChemSpider

Reference/BioCyc HCO3
type: UnificationXref
id: HCO3
db: BioCyc

Reference/ChemSpider 5745
type: UnificationXref
id: 5745
db: ChemSpider

Reference/HMDB HMDB0001080
type: UnificationXref
id: HMDB0001080
db: HMDB

Reference/ChEBI CHEBI 15380
type: UnificationXref
id: CHEBI:15380
db: ChEBI

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Succinyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00091
xref: Reference/CAS 604-98-8
xref: Reference/ChemSpider 388307
xref: Reference/PubChem-compound 439161
xref: Reference/ChEBI CHEBI 15380
xref: Reference/BioCyc 3-METHYLBENZYLSUCCINYL-COA
xref: Reference/HMDB HMDB0001022
chemical formula: C25H40N7O19P3S
molecular weight: 867.1312
structure: ChemicalStructure/PW C000808

Reference/BioCyc L-ASPARTATE
type: UnificationXref
id: L-ASPARTATE
db: BioCyc

Reference/ChemSpider 1143
type: UnificationXref
id: 1143
db: ChemSpider

Spermidine N(1)-acetyltransferase
type: ProteinReference
xref: Reference/UniProt P0A951
organism: Escherichia coli

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Carbamoyl-phosphate synthase large chain
type: Protein
entity reference: Carbamoyl-phosphate synthase large chain

Gamma-glutamylputrescine oxidoreductase
type: ProteinReference
xref: Reference/UniProt P37906

Reference/UniProt P18335
type: UnificationXref
id: P18335
db: UniProt

Reference/BioCyc UREA
type: UnificationXref
id: UREA
db: BioCyc

Reference/BioCyc L-CITRULLINE
type: UnificationXref
id: L-CITRULLINE
db: BioCyc

Reference/ChEBI CHEBI 16240
type: UnificationXref
id: CHEBI:16240
db: ChEBI

Aldehyde dehydrogenase-like protein yneI
type: ProteinReference
xref: Reference/UniProt P76149

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc AGMATHINE
type: UnificationXref
id: AGMATHINE
db: BioCyc

ChemicalStructure/PW C001092
type: ChemicalStructure
structure format: SMILES
structure data: NCCCCN

Reference/HMDB HMDB0001096
type: UnificationXref
id: HMDB0001096
db: HMDB

Reference/PubChem-compound 23724570
type: UnificationXref
id: 23724570
db: PubChem-compound

Reference/SMPDB SMP0000792
type: UnificationXref
id: SMP0000792
db: SMPDB

ChemicalStructure/PW C000808
type: ChemicalStructure
structure format: SMILES

Gamma-glutamyl-gamma-aminobutyrate hydrolase
type: Protein
cellular location: Cytosol
entity reference: Gamma-glutamyl-gamma-aminobutyrate hydrolase

Compound/PW C000032/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 1.0

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Ammonium
type: SmallMolecule
entity reference: Ammonium

Reference/ChEBI CHEBI 17148
type: UnificationXref
id: CHEBI:17148
db: ChEBI

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Carbamoyl phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 278
xref: Reference/BioCyc CARBAMOYL-P
xref: Reference/ChemSpider 272
xref: Reference/HMDB HMDB0001096
xref: Reference/CAS 590-55-6
xref: Reference/KEGG Compound C00169
xref: Reference/ChEBI CHEBI 17672
chemical formula: CH4NO5P
molecular weight: 140.98271
structure: ChemicalStructure/PW C000862

Reference/KEGG Compound C00232
type: UnificationXref
id: C00232
db: KEGG Compound

Compound/PW C007718 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-(Glutamylamino) butanoate
stoichiometric coefficient: 1.0

Compound/PW C001387 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetylputrescine
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/BioCyc SUC
type: UnificationXref
id: SUC
db: BioCyc

Acetylornithine/succinyldiaminopimelate aminotransferase
type: ProteinReference
xref: Reference/UniProt P18335

Protein/6663 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Agmatinase
stoichiometric coefficient: 2.0

ReactionCatalysis144515
type: Catalysis
controller: N-acetyl-gamma-glutamyl-phosphate reductase
controlled: Reaction154145
control type: ACTIVATION

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/CAS 110-60-1
type: UnificationXref
id: 110-60-1
db: CAS

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Compound/PW C000500/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C05932
type: UnificationXref
id: C05932
db: KEGG Compound

Reference/BioCyc CPD-9000
type: UnificationXref
id: CPD-9000
db: BioCyc

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

N-Acetyl-L-glutamic acid
type: SmallMolecule
entity reference: N-Acetyl-L-glutamic acid

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

NADPH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADPH

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

N-succinylglutamate 5-semialdehyde dehydrogenase
type: Protein
entity reference: N-succinylglutamate 5-semialdehyde dehydrogenase

Succinylglutamate desuccinylase
type: Protein
entity reference: Succinylglutamate desuccinylase

N-succinylarginine dihydrolase
type: Protein
entity reference: N-succinylarginine dihydrolase

Compound/PW C001034/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 2.0

Coenzyme A
type: SmallMolecule
cellular location: Cytosol
entity reference: Coenzyme A

Compound/PW C001783/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen peroxide
stoichiometric coefficient: 1.0

TCA Cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway85074
pathway component: SubPathwayInteraction85074
xref: Reference/SMPDB SMP0000802
xref: Reference/PathWhiz PW000779
name: SubPathway

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Compound/PW C000071 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: γ-Aminobutyric acid
stoichiometric coefficient: 1.0

4-Aminobutyraldehyde
type: SmallMoleculeReference
xref: Reference/ChemSpider 115
xref: Reference/CAS 4390-05-0
xref: Reference/ChEBI CHEBI 17769
xref: Reference/HMDB HMDB0001080
xref: Reference/PubChem-compound 118
xref: Reference/KEGG Compound C00555
xref: Reference/BioCyc 4-AMINO-BUTYRALDEHYDE
chemical formula: C4H9NO
molecular weight: 87.06841
structure: ChemicalStructure/PW C000849

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Arginine Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/9082925
pathway order: PathwayEnzymeReaction/4841
pathway order: PathwayEnzymeReaction/1732482
pathway order: PathwayEnzymeReaction/4836
pathway order: PathwayEnzymeReaction/4835
pathway order: PathwayEnzymeReaction/1732722
pathway order: PathwayEnzymeReaction/4832
pathway order: PathwayEnzymeReaction/4876
pathway order: PathwayEnzymeReaction/1732444
pathway order: PathwayEnzymeReaction/4831
pathway order: PathwayEnzymeReaction/1732443
pathway order: PathwayEnzymeReaction/4834
pathway order: PathwayEnzymeReaction/4833
pathway order: PathwayEnzymeReaction/1732445
pathway order: PathwayEnzymeReaction/4839
pathway order: PathwaySubPathway/85074
pathway order: PathwayEnzymeReaction/22165
pathway order: PathwayEnzymeReaction/4830
pathway order: PathwayEnzymeReaction/4846
pathway order: PathwayEnzymeReaction/4827
pathway order: PathwayEnzymeReaction/4848
pathway order: PathwayEnzymeReaction/4842
pathway order: PathwayEnzymeReaction/4823
pathway order: PathwayEnzymeReaction/4845
pathway order: PathwayEnzymeReaction/4822
pathway order: PathwayEnzymeReaction/4844
pathway order: PathwaySubPathway/562788
pathway order: PathwayEnzymeReaction/4829
pathway component: D-Glutamine and D-Glutamate Metabolism
pathway component: ReactionCatalysis144515
pathway component: Reaction2002578
pathway component: Reaction2694
pathway component: ReactionCatalysis2034049
pathway component: ReactionCatalysis2668
pathway component: 1.2.1.79
pathway component: 1.2.1.16
pathway component: 1.2.1.19
pathway component: 2.6.1.19
pathway component: ReactionCatalysis2669
pathway component: ReactionCatalysis2664
pathway component: 4.3.2.1
pathway component: ReactionCatalysis2663
pathway component: Reaction154145
pathway component: Reaction2649
pathway component: TCA Cycle
pathway component: 4.1.1.19
pathway component: ReactionCatalysis2677
pathway component: ReactionCatalysis2676
pathway component: 3.5.3.11
pathway component: 1.2.1.71
pathway component: ReactionCatalysis2679
pathway component: 3.5.1.96
pathway component: ReactionCatalysis2678
pathway component: 2.6.1.81
pathway component: ReactionCatalysis2671
pathway component: 2.6.1.82
pathway component: ReactionCatalysis2670
pathway component: ReactionCatalysis2673
pathway component: 1.2.1.5
pathway component: ReactionCatalysis2672
pathway component: 3.5.1.94
pathway component: ReactionCatalysis2675
pathway component: 6.3.1.11
pathway component: ReactionCatalysis2674
pathway component: 1.4.3.-
pathway component: ReactionCatalysis2687
pathway component: Reaction2670
pathway component: 2.7.2.8
pathway component: ReactionCatalysis2645
pathway component: ReactionCatalysis2680
pathway component: 2.3.1.109
pathway component: ReactionCatalysis2682
pathway component: 3.5.3.23
pathway component: ReactionCatalysis2681
pathway component: ReactionCatalysis2684
pathway component: 2.1.3.3
pathway component: 6.3.5.5
pathway component: ReactionCatalysis2683
pathway component: ReactionCatalysis2642

Compound/PW C001856/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetylornithine
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Carbamoyl phosphate
type: SmallMolecule
entity reference: Carbamoyl phosphate

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00027
type: UnificationXref
id: C00027
db: KEGG Compound

L-Glutamic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Glutamic acid
name: SubPathwayOutput

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Reference/BioCyc ACET
type: UnificationXref
id: ACET
db: BioCyc

NADP
type: SmallMolecule
cellular location: Cytosol
entity reference: NADP

Compound/PW C040858/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-(γ-glutamylamino)butanal
stoichiometric coefficient: 1.0

Reference/PubChem-compound 769
type: UnificationXref
id: 769
db: PubChem-compound

Compound/PW C000888/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-L-glutamic acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00033
type: UnificationXref
id: C00033
db: KEGG Compound

Reference/HMDB HMDB0000134
type: UnificationXref
id: HMDB0000134
db: HMDB

ChemicalStructure/PW C000174
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(O)=O

Hydrogen peroxide
type: SmallMolecule
entity reference: Hydrogen peroxide

Reference/UniProt P50457
type: UnificationXref
id: P50457
db: UniProt

Reference/KEGG Compound C15767
type: UnificationXref
id: C15767
db: KEGG Compound

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

N-Acetyl-L-glutamate 5-semialdehyde
type: SmallMolecule
cellular location: Cytosol
entity reference: N-Acetyl-L-glutamate 5-semialdehyde

Reference/KEGG Compound C00042
type: UnificationXref
id: C00042
db: KEGG Compound

Reference/KEGG Compound C00049
type: UnificationXref
id: C00049
db: KEGG Compound

Reference/KEGG Compound C00288
type: UnificationXref
id: C00288
db: KEGG Compound

Reference/CAS 56-85-9
type: UnificationXref
id: 56-85-9
db: CAS

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis2034049
type: Catalysis
controller: spermidine acetyltransferase
controlled: Reaction2002578
control type: ACTIVATION

CREB3L2-PPARgamma
type: ProteinReference
xref: Reference/UniProt Q86WD1

Reference/CAS 604-98-8
type: UnificationXref
id: 604-98-8
db: CAS

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Urea
type: SmallMoleculeReference
xref: Reference/BioCyc UREA
xref: Reference/CAS 57-13-6
xref: Reference/KEGG Compound C00086
xref: Reference/HMDB HMDB0000294
xref: Reference/ChemSpider 1143
xref: Reference/PubChem-compound 1176
xref: Reference/ChEBI CHEBI 16199
chemical formula: CH4N2O
molecular weight: 60.032364
structure: ChemicalStructure/PW C000200

Reference/PubChem-compound 784
type: UnificationXref
id: 784
db: PubChem-compound

Compound/PW C001092 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Putrescine
stoichiometric coefficient: 1.0

N-Acetyl-L-glutamic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00624
xref: Reference/ChEBI CHEBI 12575
xref: Reference/HMDB HMDB0001138
xref: Reference/BioCyc ACETYL-GLU
xref: Reference/CAS 1188-37-0
xref: Reference/PubChem-compound 185
xref: Reference/ChemSpider 180
chemical formula: C7H11NO5
molecular weight: 189.06372
structure: ChemicalStructure/PW C000888

Reference/CAS 4390-05-0
type: UnificationXref
id: 4390-05-0
db: CAS

Reference/BioCyc FUM
type: UnificationXref
id: FUM
db: BioCyc

Reference/ChEBI CHEBI 18012
type: UnificationXref
id: CHEBI:18012
db: ChEBI

ChemicalStructure/PW C000396
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCCNC(N)=N)C(O)=O

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Argininosuccinate lyase
type: Protein
entity reference: Argininosuccinate lyase

Reference/KEGG Compound C00062
type: UnificationXref
id: C00062
db: KEGG Compound

Gamma-aminobutyraldehyde dehydrogenase
type: Protein
entity reference: Gamma-aminobutyraldehyde dehydrogenase

Succinylornithine transaminase
type: Protein
entity reference: Succinylornithine transaminase

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C002749/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-L-glutamyl 5-phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00064
type: UnificationXref
id: C00064
db: KEGG Compound

Reference/HMDB HMDB0001259
type: UnificationXref
id: HMDB0001259
db: HMDB

4-(Glutamylamino) butanoate
type: SmallMolecule
cellular location: Cytosol
entity reference: 4-(Glutamylamino) butanoate

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Agmatine
type: SmallMolecule
entity reference: Agmatine

Reference/KEGG Compound C00077
type: UnificationXref
id: C00077
db: KEGG Compound

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/HMDB HMDB0001022
type: UnificationXref
id: HMDB0001022
db: HMDB

Reaction2002578
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001092 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001387 Cytosol/Stoichiometry/1.0
right: Coenzyme A
right: N-Acetylputrescine
spontaneous: false
left: Acetyl-CoA
left: Putrescine
name: Acetyl-CoA + Putrescine ↔ Coenzyme A + N-Acetylputrescine
conversion direction: REVERSIBLE

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/HMDB HMDB0012161
type: UnificationXref
id: HMDB0012161
db: HMDB

Reference/KEGG Compound C00086
type: UnificationXref
id: C00086
db: KEGG Compound

Reference/CAS 5699-41-2
type: UnificationXref
id: 5699-41-2
db: CAS

Reference/KEGG Compound C00091
type: UnificationXref
id: C00091
db: KEGG Compound

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Carbamoyl phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Carbamoyl phosphate

Aldehyde dehydrogenase-like protein yneI
type: Protein
entity reference: Aldehyde dehydrogenase-like protein yneI

Reference/ChEBI CHEBI 18050
type: UnificationXref
id: CHEBI:18050
db: ChEBI

Hydrogen peroxide
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003125
xref: Reference/PubChem-compound 784
xref: Reference/ChemSpider 763
xref: Reference/CAS 7722-84-1
xref: Reference/BioCyc HYDROGEN-PEROXIDE
xref: Reference/ChEBI CHEBI 16240
xref: Reference/KEGG Compound C00027
chemical formula: H2O2
molecular weight: 34.005478
structure: ChemicalStructure/PW C001783

Reference/BioCyc 4-AMINO-BUTYRATE
type: UnificationXref
id: 4-AMINO-BUTYRATE
db: BioCyc

Reference/HMDB HMDB0000191
type: UnificationXref
id: HMDB0000191
db: HMDB

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Gamma-glutamylputrescine oxidoreductase
type: Protein
entity reference: Gamma-glutamylputrescine oxidoreductase

Compound/PW C000140 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ornithine
stoichiometric coefficient: 1.0

Reference/UniProt P06960
type: UnificationXref
id: P06960
db: UniProt

Ornithine carbamoyltransferase chain F
type: ProteinReference
xref: Reference/UniProt P06960
organism: Escherichia coli

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

ChemicalStructure/PW C040858
type: ChemicalStructure
structure format: SMILES
structure data: NC(CCC(=O)NCCCC=O)C([O-])=O

ChemicalStructure/PW C040857
type: ChemicalStructure
structure format: SMILES
structure data: [O-]C(=O)CC[C@H](NC(=O)CCC([O-])=O)C([O-])=O

ChemicalStructure/PW C040856
type: ChemicalStructure
structure format: SMILES
structure data: NC(=[NH2+])NCCC[C@H](NC(=O)CCC([O-])=O)C([O-])=O

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/UniProt P0A951
type: UnificationXref
id: P0A951
db: UniProt

Hydrogen carbonate
type: SmallMolecule
entity reference: Hydrogen carbonate

Reference/ChEBI CHEBI 58241
type: UnificationXref
id: CHEBI:58241
db: ChEBI

Compound/PW C000088/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fumaric acid
stoichiometric coefficient: 1.0

Hydrogen carbonate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000595
xref: Reference/ChEBI CHEBI 17544
xref: Reference/PubChem-compound 769
xref: Reference/BioCyc HCO3
xref: Reference/ChemSpider 749
xref: Reference/CAS 71-52-3
xref: Reference/KEGG Compound C00288
chemical formula: CH2O3
molecular weight: 62.000393
structure: ChemicalStructure/PW C000463

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Acetic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15366
xref: Reference/BioCyc ACET
xref: Reference/CAS 64-19-7
xref: Reference/KEGG Compound C00033
xref: Reference/ChemSpider 171
xref: Reference/HMDB HMDB0000042
xref: Reference/PubChem-compound 176
chemical formula: C2H4O2
molecular weight: 60.02113
structure: ChemicalStructure/PW C000029

Reference/UniProt P78061
type: UnificationXref
id: P78061
db: UniProt

argininosuccinate synthase
type: Complex
component stoichiometry: Protein/5986/Stoichiometry/4.0
component: Argininosuccinate synthase

NADH
type: SmallMolecule
entity reference: NADH

Reference/PubChem-compound 21883788
type: UnificationXref
id: 21883788
db: PubChem-compound

Reference/ChemSpider 13837702
type: UnificationXref
id: 13837702
db: ChemSpider

ChemicalStructure/PW C001783
type: ChemicalStructure
structure format: SMILES
structure data: OO

Argininosuccinic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C03406
xref: Reference/ChemSpider 16059
xref: Reference/HMDB HMDB0000052
xref: Reference/PubChem-compound 16950
xref: Reference/CAS 2387-71-5
xref: Reference/ChEBI CHEBI 15682
chemical formula: C10H18N4O6
molecular weight: 290.12262
structure: ChemicalStructure/PW C000036

Acetylornithine/succinyldiaminopimelate aminotransferase
type: Protein
entity reference: Acetylornithine/succinyldiaminopimelate aminotransferase

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Reference/PubChem-compound 119
type: UnificationXref
id: 119
db: PubChem-compound

Reference/PubChem-compound 118
type: UnificationXref
id: 118
db: PubChem-compound

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/PubChem-compound 5961
type: UnificationXref
id: 5961
db: PubChem-compound

Protein/6101 Cytosol/Stoichiometry/4.0
type: Stoichiometry
physical entity: Spermidine N(1)-acetyltransferase
stoichiometric coefficient: 4.0

Reference/UniProt P25526
type: UnificationXref
id: P25526
db: UniProt

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/UniProt P22256
type: UnificationXref
id: P22256
db: UniProt

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

ChemicalStructure/PW C000463
type: ChemicalStructure
structure format: SMILES
structure data: OC(O)=O

Reference/ChEBI CHEBI 15729
type: UnificationXref
id: CHEBI:15729
db: ChEBI

Compound/PW C000940/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase
type: Complex
component stoichiometry: Protein/6372/Stoichiometry/2.0
component: Acetylornithine/succinyldiaminopimelate aminotransferase

acetylornithine deacetylase
type: Complex
component stoichiometry: Protein/6427/Stoichiometry/2.0
component: Acetylornithine deacetylase

carbamoyl phosphate synthetase
type: Complex
component stoichiometry: Protein/5989/Stoichiometry/2.0
component stoichiometry: Protein/5860/Stoichiometry/2.0
component: Carbamoyl-phosphate synthase large chain
component: Carbamoyl-phosphate synthase small chain

Argininosuccinic acid
type: SmallMolecule
entity reference: Argininosuccinic acid

acetylglutamate kinase
type: Complex
component stoichiometry: Protein/5981/Stoichiometry/2.0
component: Acetylglutamate kinase

N-acetylglutamate synthase
type: Complex
component stoichiometry: Protein/5096/Stoichiometry/6.0
component: CREB3L2-PPARgamma

Adenosine monophosphate
type: SmallMolecule
entity reference: Adenosine monophosphate

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reference/ChemSpider 272
type: UnificationXref
id: 272
db: ChemSpider

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

GLUTAMINE-PUTRESCINE LIGASE
type: Complex
component stoichiometry: Protein/6804/Stoichiometry/12.0
component: Gamma-glutamylputrescine synthetase

Agmatine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001432
xref: Reference/CAS 306-60-5
xref: Reference/BioCyc AGMATHINE
xref: Reference/ChemSpider 194
xref: Reference/PubChem-compound 199
xref: Reference/ChEBI CHEBI 17431
xref: Reference/KEGG Compound C00179
chemical formula: C5H14N4
molecular weight: 130.12184
structure: ChemicalStructure/PW C001107

Acetic acid
type: SmallMolecule
entity reference: Acetic acid

arginine decarboxylase
type: Complex
component stoichiometry: Protein/6475/Stoichiometry/10.0
component: Biodegradative arginine decarboxylase

Compound/PW C000414/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 2.0

succinylarginine dihydrolase
type: Complex
component stoichiometry: Protein/6742/Stoichiometry/2.0
component: N-succinylarginine dihydrolase

Reference/HMDB HMDB0001414
type: UnificationXref
id: HMDB0001414
db: HMDB

ChemicalStructure/PW C000200
type: ChemicalStructure
structure format: SMILES
structure data: NC(N)=O

succinylornithine transaminase
type: Complex
component stoichiometry: Protein/6790/Stoichiometry/2.0
component: Succinylornithine transaminase

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Reference/BioCyc GAMMA-GLUTAMYL-PUTRESCINE
type: UnificationXref
id: GAMMA-GLUTAMYL-PUTRESCINE
db: BioCyc

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

γ-Aminobutyric acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000112
xref: Reference/ChemSpider 116
xref: Reference/PubChem-compound 119
xref: Reference/CAS 56-12-2
xref: Reference/BioCyc 4-AMINO-BUTYRATE
xref: Reference/ChEBI CHEBI 16865
xref: Reference/KEGG Compound C00334
chemical formula: C4H9NO2
molecular weight: 103.06333
structure: ChemicalStructure/PW C000071

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/CAS 692-29-5
type: UnificationXref
id: 692-29-5
db: CAS

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/ChEBI CHEBI 16865
type: UnificationXref
id: CHEBI:16865
db: ChEBI

Reference/BioCyc ACETYL-GLU
type: UnificationXref
id: ACETYL-GLU
db: BioCyc

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

ChemicalStructure/PW C001107
type: ChemicalStructure
structure format: SMILES
structure data: NCCCCNC(N)=N

4-(Glutamylamino) butanoate
type: SmallMolecule
entity reference: 4-(Glutamylamino) butanoate

Urea
type: SmallMolecule
cellular location: Cytosol
entity reference: Urea

Reference/HMDB HMDB0001432
type: UnificationXref
id: HMDB0001432
db: HMDB

Fumaric acid
type: SmallMolecule
entity reference: Fumaric acid

Compound/PW C007718/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-(Glutamylamino) butanoate
stoichiometric coefficient: 1.0

Fumaric acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000134
xref: Reference/ChemSpider 10197150
xref: Reference/CAS 110-17-8
xref: Reference/PubChem-compound 21883788
xref: Reference/KEGG Compound C00122
xref: Reference/BioCyc FUM
xref: Reference/ChEBI CHEBI 18012
chemical formula: C4H4O4
molecular weight: 116.010956
structure: ChemicalStructure/PW C000088

CREB3L2-PPARgamma
type: Protein
entity reference: CREB3L2-PPARgamma

Reference/ChEBI CHEBI 15741
type: UnificationXref
id: CHEBI:15741
db: ChEBI

Compound/PW C000174 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 1112
type: UnificationXref
id: 1112
db: PubChem-compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/PubChem-compound 127370
type: UnificationXref
id: 127370
db: PubChem-compound

Reference/PubChem-compound 1110
type: UnificationXref
id: 1110
db: PubChem-compound

Reference/HMDB HMDB0000112
type: UnificationXref
id: HMDB0000112
db: HMDB

Reference/HMDB HMDB0000595
type: UnificationXref
id: HMDB0000595
db: HMDB

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

N-Acetylputrescine
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-569
xref: Reference/KEGG Compound C02714
xref: Reference/ChEBI CHEBI 17768
xref: Reference/PubChem-compound 122356
xref: Reference/HMDB HMDB0002064
xref: Reference/ChemSpider 109095
xref: Reference/CAS 5699-41-2
chemical formula: C6H14N2O
molecular weight: 130.11061
structure: ChemicalStructure/PW C001387

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

γ-Aminobutyric acid
type: SmallMolecule
entity reference: γ-Aminobutyric acid

Ornithine carbamoyltransferase chain I
type: ProteinReference
xref: Reference/UniProt P04391
organism: Escherichia coli

Carbamoyl-phosphate synthase large chain
type: ProteinReference
xref: Reference/UniProt P00968

Reference/ChemSpider 16059
type: UnificationXref
id: 16059
db: ChemSpider

Reference/CAS 899816-95-6
type: UnificationXref
id: 899816-95-6
db: CAS

Compound/PW C000396/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Arginine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000849
type: ChemicalStructure
structure format: SMILES
structure data: NCCCC=O

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Reference/BioCyc SUCC-S-ALD
type: UnificationXref
id: SUCC-S-ALD
db: BioCyc

N-Acetylputrescine
type: SmallMolecule
cellular location: Cytosol
entity reference: N-Acetylputrescine

Compound/PW C040034 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 2.0

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

D-Glutamine and D-Glutamate Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway562788
pathway component: SubPathwayInteraction562788
xref: Reference/PathWhiz PW000769
xref: Reference/SMPDB SMP0000792
name: SubPathway

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/BioCyc CPD-822
type: UnificationXref
id: CPD-822
db: BioCyc

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Compound/PW C040857/Stoichiometry/1.0
type: Stoichiometry
physical entity: N2-succinylglutamate
stoichiometric coefficient: 1.0

Gamma-glutamyl-gamma-aminobutyrate hydrolase
type: ProteinReference
xref: Reference/UniProt P76038
organism: Escherichia coli

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Reference/ChemSpider 1078
type: UnificationXref
id: 1078
db: ChemSpider

Reference/PubChem-compound 199
type: UnificationXref
id: 199
db: PubChem-compound

Ornithine
type: SmallMolecule
cellular location: Cytosol
entity reference: Ornithine

Reference/UniProt P37906
type: UnificationXref
id: P37906
db: UniProt

ChemicalStructure/PW C000862
type: ChemicalStructure
structure format: SMILES
structure data: NC(=O)OP(O)(O)=O

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

Reference/ChemSpider 1080
type: UnificationXref
id: 1080
db: ChemSpider

Compound/PW C040856/Stoichiometry/1.0
type: Stoichiometry
physical entity: N2-succinyl-L-arginine
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0006488
type: UnificationXref
id: HMDB0006488
db: HMDB

Compound/PW C000140/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ornithine
stoichiometric coefficient: 1.0

Reference/UniProt P76038
type: UnificationXref
id: P76038
db: UniProt

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/ChEBI CHEBI 16878
type: UnificationXref
id: CHEBI:16878
db: ChEBI

4-(Glutamylamino) butanoate
type: SmallMoleculeReference
xref: Reference/CAS 5105-96-4
xref: Reference/ChEBI CHEBI 49260
xref: Reference/ChemSpider 21865667
xref: Reference/HMDB HMDB0012161
xref: Reference/BioCyc CPD-9000
xref: Reference/KEGG Compound C15767
xref: Reference/PubChem-compound 23724570
chemical formula: C9H16N2O5
molecular weight: 232.10593
structure: ChemicalStructure/PW C007718

N-succinylglutamate 5-semialdehyde dehydrogenase
type: ProteinReference
xref: Reference/UniProt P76217

N-succinylarginine dihydrolase
type: ProteinReference
xref: Reference/UniProt P76216

Succinylglutamate desuccinylase
type: ProteinReference
xref: Reference/UniProt P76215

Protein/5981/Stoichiometry/2.0
type: Stoichiometry
physical entity: Acetylglutamate kinase
stoichiometric coefficient: 2.0

Compound/PW C000723/Stoichiometry/1.0
type: Stoichiometry
physical entity: Citrulline
stoichiometric coefficient: 1.0

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/PubChem-compound 28782
type: UnificationXref
id: 28782
db: PubChem-compound

Protein/5096/Stoichiometry/6.0
type: Stoichiometry
physical entity: CREB3L2-PPARgamma
stoichiometric coefficient: 6.0

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

Reference/ChemSpider 20148392
type: UnificationXref
id: 20148392
db: ChemSpider

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

Reference/UniProt P77581
type: UnificationXref
id: P77581
db: UniProt

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Reference/ChEBI CHEBI 15366
type: UnificationXref
id: CHEBI:15366
db: ChEBI

Reference/ChEBI CHEBI 17544
type: UnificationXref
id: CHEBI:17544
db: ChEBI

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

ChemicalStructure/PW C000888
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)N[C@@H](CCC(O)=O)C(O)=O

Compound/PW C000174/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

N2-Succinyl-L-ornithine
type: SmallMolecule
entity reference: N2-Succinyl-L-ornithine

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Protein/6427/Stoichiometry/2.0
type: Stoichiometry
physical entity: Acetylornithine deacetylase
stoichiometric coefficient: 2.0

Reference/PubChem-compound 1176
type: UnificationXref
id: 1176
db: PubChem-compound

Reference/CAS 110-15-6
type: UnificationXref
id: 110-15-6
db: CAS

γ-aminobutyraldehyde dehydrogenase
type: Complex
component stoichiometry: Protein/6796/Stoichiometry/4.0
component: Gamma-aminobutyraldehyde dehydrogenase

4-aminobutyrate aminotransferase
type: Complex
component stoichiometry: Protein/6407/Stoichiometry/2.0
component: 4-aminobutyrate aminotransferase_
component: 4-aminobutyrate aminotransferase

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/ChEBI CHEBI 16467
type: UnificationXref
id: CHEBI:16467
db: ChEBI

Reference/BioCyc N-ACETYL-GLUTAMYL-P
type: UnificationXref
id: N-ACETYL-GLUTAMYL-P
db: BioCyc

Compound/PW C001107 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Agmatine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

N2-Succinyl-L-glutamic acid 5-semialdehyde
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-822
xref: Reference/ChEBI CHEBI 27657
xref: Reference/HMDB HMDB0001180
xref: Reference/KEGG Compound C05932
xref: Reference/PubChem-compound 440848
xref: Reference/ChemSpider 389690
chemical formula: C9H13NO6
molecular weight: 231.07428
structure: ChemicalStructure/PW C000916

Compound/PW C022608/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

N2-Succinyl-L-glutamic acid 5-semialdehyde
type: SmallMolecule
entity reference: N2-Succinyl-L-glutamic acid 5-semialdehyde

Reference/ChemSpider 167387
type: UnificationXref
id: 167387
db: ChemSpider

Reference/ChEBI CHEBI 17769
type: UnificationXref
id: CHEBI:17769
db: ChEBI

Reference/CAS 56-12-2
type: UnificationXref
id: 56-12-2
db: CAS

Reference/KEGG Compound C02714
type: UnificationXref
id: C02714
db: KEGG Compound

Reference/ChEBI CHEBI 17768
type: UnificationXref
id: CHEBI:17768
db: ChEBI

Reference/ChemSpider 389220
type: UnificationXref
id: 389220
db: ChemSpider

Reference/PubChem-compound 185
type: UnificationXref
id: 185
db: PubChem-compound

Succinylornithine transaminase
type: ProteinReference
xref: Reference/UniProt P77581

Protein/6732 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Gamma-glutamyl-gamma-aminobutyrate hydrolase
stoichiometric coefficient: 2.0

Compound/PW C001099 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/BioCyc 3-METHYLBENZYLSUCCINYL-COA
type: UnificationXref
id: 3-METHYLBENZYLSUCCINYL-COA
db: BioCyc

Succinate-semialdehyde dehydrogenase [NADP+]
type: Protein
cellular location: Cytosol
entity reference: Succinate-semialdehyde dehydrogenase [NADP+]

Compound/PW C040034/Stoichiometry/2.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 27574
type: UnificationXref
id: CHEBI:27574
db: ChEBI

Reference/CAS 74-79-3
type: UnificationXref
id: 74-79-3
db: CAS

Compound/PW C000071/Stoichiometry/1.0
type: Stoichiometry
physical entity: γ-Aminobutyric acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 109095
type: UnificationXref
id: 109095
db: ChemSpider

Reference/HMDB HMDB0000517
type: UnificationXref
id: HMDB0000517
db: HMDB

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Gamma-aminobutyraldehyde dehydrogenase
type: ProteinReference
xref: Reference/UniProt P77674

Argininosuccinate lyase
type: ProteinReference
xref: Reference/UniProt P11447

Gamma-glutamylputrescine synthetase
type: Protein
entity reference: Gamma-glutamylputrescine synthetase

N-acetyl-gamma-glutamyl-phosphate reductase
type: ProteinReference
xref: Reference/UniProt P11446
organism: Escherichia coli

Reference/PubChem-compound 176
type: UnificationXref
id: 176
db: PubChem-compound

γ-glutamyl-L-putrescine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 20841830
xref: Reference/ChemSpider 20148392
xref: Reference/HMDB HMDB0012230
xref: Reference/BioCyc GAMMA-GLUTAMYL-PUTRESCINE
xref: Reference/ChEBI CHEBI 48005
xref: Reference/KEGG Compound C15699
chemical formula: C9H19N3O3
molecular weight: 217.14264
structure: ChemicalStructure/PW C007776

γ-glutamyl-L-putrescine
type: SmallMolecule
entity reference: γ-glutamyl-L-putrescine

Compound/PW C001420/Stoichiometry/2.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 2.0

Protein/6796/Stoichiometry/4.0
type: Stoichiometry
physical entity: Gamma-aminobutyraldehyde dehydrogenase
stoichiometric coefficient: 4.0

Reference/UniProt P76216
type: UnificationXref
id: P76216
db: UniProt

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/BioCyc N2-SUCCINYLORNITHINE
type: UnificationXref
id: N2-SUCCINYLORNITHINE
db: BioCyc

Reference/UniProt P76217
type: UnificationXref
id: P76217
db: UniProt

Reference/UniProt P76215
type: UnificationXref
id: P76215
db: UniProt

Reference/ChEBI CHEBI 48005
type: UnificationXref
id: CHEBI:48005
db: ChEBI

Compound/PW C002771 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-L-glutamate 5-semialdehyde
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/CAS 7722-84-1
type: UnificationXref
id: 7722-84-1
db: CAS

Reference/PubChem-compound 6262
type: UnificationXref
id: 6262
db: PubChem-compound

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/HMDB HMDB0001180
type: UnificationXref
id: HMDB0001180
db: HMDB

Compound/PW C001092/Stoichiometry/1.0
type: Stoichiometry
physical entity: Putrescine
stoichiometric coefficient: 1.0

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Succinic acid semialdehyde
type: SmallMolecule
entity reference: Succinic acid semialdehyde

Reference/KEGG Compound C00555
type: UnificationXref
id: C00555
db: KEGG Compound

Succinate-semialdehyde dehydrogenase [NADP+]
type: ProteinReference
xref: Reference/UniProt P25526
organism: Escherichia coli

Reference/BioCyc 4-AMINO-BUTYRALDEHYDE
type: UnificationXref
id: 4-AMINO-BUTYRALDEHYDE
db: BioCyc

Reference/HMDB HMDB0003125
type: UnificationXref
id: HMDB0003125
db: HMDB

Compound/PW C001065/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 1.0

Reference/CAS 110-17-8
type: UnificationXref
id: 110-17-8
db: CAS

Compound/PW C000972 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid semialdehyde
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 58763
type: UnificationXref
id: CHEBI:58763
db: ChEBI

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/ChemSpider 388369
type: UnificationXref
id: 388369
db: ChemSpider

Reference/KEGG Compound C00327
type: UnificationXref
id: C00327
db: KEGG Compound

Agmatinase
type: Protein
cellular location: Cytosol
entity reference: Agmatinase

NAD
type: SmallMolecule
entity reference: NAD

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/ChemSpider 389690
type: UnificationXref
id: 389690
db: ChemSpider

Citrulline
type: SmallMolecule
entity reference: Citrulline

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C007776
type: ChemicalStructure
structure format: SMILES
structure data: NCCCCNC(=O)CC[C@H](N)C(O)=O

Protein/6444 Cytosol/Stoichiometry/4.0
type: Stoichiometry
physical entity: Succinate-semialdehyde dehydrogenase [NADP+]
stoichiometric coefficient: 4.0

Compound/PW C002749 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-L-glutamyl 5-phosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001199
type: UnificationXref
id: HMDB0001199
db: HMDB

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Carbamoyl-phosphate synthase small chain
type: Protein
entity reference: Carbamoyl-phosphate synthase small chain

Argininosuccinate synthase
type: Protein
entity reference: Argininosuccinate synthase

Reference/KEGG Compound C00334
type: UnificationXref
id: C00334
db: KEGG Compound

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

Acetylglutamate kinase
type: Protein
entity reference: Acetylglutamate kinase

Arginine N-succinyltransferase
type: ProteinReference
xref: Reference/UniProt P0AE37

Reference/PubChem-compound 192878
type: UnificationXref
id: 192878
db: PubChem-compound

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

Reference/BioCyc ARG
type: UnificationXref
id: ARG
db: BioCyc

N2-Succinyl-L-ornithine
type: SmallMoleculeReference
xref: Reference/BioCyc N2-SUCCINYLORNITHINE
xref: Reference/PubChem-compound 127370
xref: Reference/KEGG Compound C03415
xref: Reference/ChemSpider 113025
xref: Reference/HMDB HMDB0001199
xref: Reference/CAS 899816-95-6
xref: Reference/ChEBI CHEBI 27574
chemical formula: C9H16N2O5
molecular weight: 232.10593
structure: ChemicalStructure/PW C000934

Acetyl-CoA
type: SmallMolecule
entity reference: Acetyl-CoA

Reference/PubChem-compound 16950
type: UnificationXref
id: 16950
db: PubChem-compound

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Biodegradative arginine decarboxylase
type: ProteinReference
xref: Reference/UniProt P28629

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/HMDB HMDB0002064
type: UnificationXref
id: HMDB0002064
db: HMDB

Spermidine N(1)-acetyltransferase
type: Protein
cellular location: Cytosol
entity reference: Spermidine N(1)-acetyltransferase

Reference/CAS 5105-96-4
type: UnificationXref
id: 5105-96-4
db: CAS

Compound/PW C000146 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

L-Glutamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000641
xref: Reference/ChEBI CHEBI 18050
xref: Reference/ChemSpider 5746
xref: Reference/BioCyc GLN
xref: Reference/KEGG Compound C00064
xref: Reference/PubChem-compound 5961
xref: Reference/CAS 56-85-9
chemical formula: C5H10N2O3
molecular weight: 146.06914
structure: ChemicalStructure/PW C000500

Putrescine aminotransferase
type: Protein
entity reference: Putrescine aminotransferase

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Compound/PW C000463/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen carbonate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 49260
type: UnificationXref
id: CHEBI:49260
db: ChEBI

Reference/UniProt P0AE37
type: UnificationXref
id: P0AE37
db: UniProt

Reference/KEGG Compound C00122
type: UnificationXref
id: C00122
db: KEGG Compound

Reference/PubChem-compound 122356
type: UnificationXref
id: 122356
db: PubChem-compound

N-Acetylornithine
type: SmallMolecule
entity reference: N-Acetylornithine

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

ChemicalStructure/PW C000934
type: ChemicalStructure
structure format: SMILES
structure data: NCCC[C@H](NC(=O)CCC(O)=O)C(O)=O

Reference/CAS 6205-08-9
type: UnificationXref
id: 6205-08-9
db: CAS

Citrulline
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00327
xref: Reference/CAS 372-75-8
xref: Reference/ChEBI CHEBI 16349
xref: Reference/PubChem-compound 6992098
xref: Reference/BioCyc L-CITRULLINE
xref: Reference/HMDB HMDB0000904
xref: Reference/ChemSpider 9367
chemical formula: C6H13N3O3
molecular weight: 175.09569
structure: ChemicalStructure/PW C000723

Reference/CAS 372-75-8
type: UnificationXref
id: 372-75-8
db: CAS

Reference/KEGG Compound C03406
type: UnificationXref
id: C03406
db: KEGG Compound

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/PubChem-compound 44367445
type: UnificationXref
id: 44367445
db: PubChem-compound

4-aminobutyrate aminotransferase_
type: Protein
entity reference: 4-aminobutyrate aminotransferase_

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/HMDB HMDB0000904
type: UnificationXref
id: HMDB0000904
db: HMDB

Reference/KEGG Compound C00134
type: UnificationXref
id: C00134
db: KEGG Compound

Reference/UniProt Q86WD1
type: UnificationXref
id: Q86WD1
db: UniProt

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Compound/PW C000723 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Citrulline
stoichiometric coefficient: 1.0

Protein/5860/Stoichiometry/2.0
type: Stoichiometry
physical entity: Carbamoyl-phosphate synthase large chain
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0006456
type: UnificationXref
id: HMDB0006456
db: HMDB

Reference/TAXONOMY 562
type: UnificationXref
id: 562
db: TAXONOMY

ChemicalStructure/PW C000916
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)N[C@@H](CCC=O)C(O)=O

Reference/ChemSpider 388307
type: UnificationXref
id: 388307
db: ChemSpider

spermidine acetyltransferase
type: Complex
component stoichiometry: Protein/6101 Cytosol/Stoichiometry/4.0
cellular location: Cytosol
component: Spermidine N(1)-acetyltransferase

Succinic acid semialdehyde
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001259
xref: Reference/BioCyc SUCC-S-ALD
xref: Reference/ChemSpider 1080
xref: Reference/CAS 692-29-5
xref: Reference/KEGG Compound C00232
xref: Reference/PubChem-compound 1112
xref: Reference/ChEBI CHEBI 16265
chemical formula: C4H6O3
molecular weight: 102.03169
structure: ChemicalStructure/PW C000972

Compound/PW C002771/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-L-glutamate 5-semialdehyde
stoichiometric coefficient: 1.0

L-Glutamine
type: SmallMolecule
entity reference: L-Glutamine

4-aminobutyrate aminotransferase
type: Protein
entity reference: 4-aminobutyrate aminotransferase

Reference/KEGG Compound C03415
type: UnificationXref
id: C03415
db: KEGG Compound

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/BioCyc PUTRESCINE
type: UnificationXref
id: PUTRESCINE
db: BioCyc

Reference/SMPDB SMP0000802
type: UnificationXref
id: SMP0000802
db: SMPDB

Reference/ChemSpider 9367
type: UnificationXref
id: 9367
db: ChemSpider

Reference/HMDB HMDB0012230
type: UnificationXref
id: HMDB0012230
db: HMDB

Compound/PW C000862/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbamoyl phosphate
stoichiometric coefficient: 1.0

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000254
type: UnificationXref
id: HMDB0000254
db: HMDB

Water
type: SmallMolecule
entity reference: Water

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

Reference/KEGG Compound C01250
type: UnificationXref
id: C01250
db: KEGG Compound

Reference/BioCyc HYDROGEN-PEROXIDE
type: UnificationXref
id: HYDROGEN-PEROXIDE
db: BioCyc

ChemicalStructure/PW C001387
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)NCCCCN

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/SMPDB SMP0000812
type: UnificationXref
id: SMP0000812
db: SMPDB

N-Acetyl-L-glutamyl 5-phosphate
type: SmallMolecule
entity reference: N-Acetyl-L-glutamyl 5-phosphate

Acetylornithine deacetylase
type: Protein
entity reference: Acetylornithine deacetylase

Reference/KEGG Compound C00169
type: UnificationXref
id: C00169
db: KEGG Compound

Compound/PW C000808/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinyl-CoA
stoichiometric coefficient: 1.0

NAD+-dependent succinate semialdehyde dehydrogenase
type: Complex
component stoichiometry: Protein/7202/Stoichiometry/2.0
component: Aldehyde dehydrogenase-like protein yneI

Reference/ChemSpider 763
type: UnificationXref
id: 763
db: ChemSpider

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase
type: Protein
entity reference: Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase

Reference/ChemSpider 10197150
type: UnificationXref
id: 10197150
db: ChemSpider

ChemicalStructure/PW C000029
type: ChemicalStructure
structure format: SMILES
structure data: CC(O)=O

N-Acetylornithine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16543
xref: Reference/ChemSpider 388369
xref: Reference/KEGG Compound C00437
xref: Reference/CAS 6205-08-9
xref: Reference/HMDB HMDB0003357
xref: Reference/PubChem-compound 439232
xref: Reference/BioCyc N-ALPHA-ACETYLORNITHINE
chemical formula: C7H14N2O3
molecular weight: 174.10045
structure: ChemicalStructure/PW C001856

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/KEGG Compound C00179
type: UnificationXref
id: C00179
db: KEGG Compound

Reference/ChEBI CHEBI 16199
type: UnificationXref
id: CHEBI:16199
db: ChEBI

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000036
type: ChemicalStructure
structure format: SMILES

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Reference/CAS 590-55-6
type: UnificationXref
id: 590-55-6
db: CAS

Protein/6372/Stoichiometry/2.0
type: Stoichiometry
physical entity: Acetylornithine/succinyldiaminopimelate aminotransferase
stoichiometric coefficient: 2.0

Compound/PW C000029/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetic acid
stoichiometric coefficient: 1.0

Compound/PW C000972/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid semialdehyde
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17053
type: UnificationXref
id: CHEBI:17053
db: ChEBI

Reference/CAS 2387-71-5
type: UnificationXref
id: 2387-71-5
db: CAS

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

Reference/HMDB HMDB0001138
type: UnificationXref
id: HMDB0001138
db: HMDB

Agmatine
type: SmallMolecule
cellular location: Cytosol
entity reference: Agmatine

Reference/HMDB HMDB0000042
type: UnificationXref
id: HMDB0000042
db: HMDB

Protein/5904 Cytosol/Stoichiometry/3.0
type: Stoichiometry
physical entity: Ornithine carbamoyltransferase chain F
stoichiometric coefficient: 3.0

SubPathwayInteraction562788
type: Interaction
name: SubPathwayReaction
name: SubPathway562788Reaction
participant: L-Glutamic acid

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

ChemicalStructure/PW C007718
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(=O)NCCCC(O)=O)C(O)=O

N-Acetyl-L-glutamate 5-semialdehyde
type: SmallMoleculeReference
xref: Reference/PubChem-compound 192878
xref: Reference/ChemSpider 167387
xref: Reference/CAS 13074-21-0
xref: Reference/KEGG Compound C01250
xref: Reference/HMDB HMDB0006488
xref: Reference/ChEBI CHEBI 16319
chemical formula: C7H11NO4
molecular weight: 173.0688
structure: ChemicalStructure/PW C002771

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

Reference/CAS 15383-57-0
type: UnificationXref
id: 15383-57-0
db: CAS

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/HMDB HMDB0000052
type: UnificationXref
id: HMDB0000052
db: HMDB

Reference/HMDB HMDB0000294
type: UnificationXref
id: HMDB0000294
db: HMDB

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Putrescine
type: SmallMolecule
cellular location: Cytosol
entity reference: Putrescine

L-Aspartic acid
type: SmallMolecule
entity reference: L-Aspartic acid

γ-glutamyl-γ-aminobutyrate hydrolase
type: Complex
component stoichiometry: Protein/6732 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Gamma-glutamyl-gamma-aminobutyrate hydrolase

L-Aspartic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 44367445
xref: Reference/ChemSpider 5745
xref: Reference/ChEBI CHEBI 17053
xref: Reference/HMDB HMDB0000191
xref: Reference/CAS 56-84-8
xref: Reference/KEGG Compound C00049
xref: Reference/BioCyc L-ASPARTATE
chemical formula: C4H7NO4
molecular weight: 133.0375
structure: ChemicalStructure/PW C000123

Reference/KEGG Compound C15699
type: UnificationXref
id: C15699
db: KEGG Compound

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/CAS 306-60-5
type: UnificationXref
id: 306-60-5
db: CAS

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

Compound/PW C001107/Stoichiometry/1.0
type: Stoichiometry
physical entity: Agmatine
stoichiometric coefficient: 1.0

N-Acetyl-L-glutamyl 5-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C04133
xref: Reference/BioCyc N-ACETYL-GLUTAMYL-P
xref: Reference/ChEBI CHEBI 16878
xref: Reference/CAS 15383-57-0
xref: Reference/ChemSpider 389220
xref: Reference/HMDB HMDB0006456
xref: Reference/PubChem-compound 440236
chemical formula: C7H12NO8P
molecular weight: 269.03006
structure: ChemicalStructure/PW C002749

N-Acetyl-L-glutamate 5-semialdehyde
type: SmallMolecule
entity reference: N-Acetyl-L-glutamate 5-semialdehyde

Biodegradative arginine decarboxylase
type: Protein
entity reference: Biodegradative arginine decarboxylase

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Arginine N-succinyltransferase
type: Protein
entity reference: Arginine N-succinyltransferase

Reference/UniProt P28629
type: UnificationXref
id: P28629
db: UniProt

ChemicalStructure/PW C000071
type: ChemicalStructure
structure format: SMILES
structure data: NCCCC(O)=O

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

Reference/CAS 56-84-8
type: UnificationXref
id: 56-84-8
db: CAS

Reference/ChemSpider 21865667
type: UnificationXref
id: 21865667
db: ChemSpider

Reference/ChemSpider 749
type: UnificationXref
id: 749
db: ChemSpider

Reference/CAS 71-52-3
type: UnificationXref
id: 71-52-3
db: CAS

ChemicalStructure/PW C000088
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)\C=C\C(O)=O

Reference/HMDB HMDB0003357
type: UnificationXref
id: HMDB0003357
db: HMDB

Reference/ChEBI CHEBI 12575
type: UnificationXref
id: CHEBI:12575
db: ChEBI

ChemicalStructure/PW C002749
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)N[C@@H](CCC(=O)OP(O)(O)=O)C(O)=O

Reference/UniProt P60651
type: UnificationXref
id: P60651
db: UniProt

Succinic acid
type: SmallMolecule
entity reference: Succinic acid

Reference/CAS 13074-21-0
type: UnificationXref
id: 13074-21-0
db: CAS

Reference/CAS 64-19-7
type: UnificationXref
id: 64-19-7
db: CAS

N-acetyl-gamma-glutamyl-phosphate reductase
type: Protein
cellular location: Cytosol
entity reference: N-acetyl-gamma-glutamyl-phosphate reductase

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/CAS 57-13-6
type: UnificationXref
id: 57-13-6
db: CAS

L-Arginine
type: SmallMoleculeReference
xref: Reference/BioCyc ARG
xref: Reference/ChEBI CHEBI 16467
xref: Reference/CAS 74-79-3
xref: Reference/KEGG Compound C00062
xref: Reference/ChemSpider 6082
xref: Reference/PubChem-compound 28782
xref: Reference/HMDB HMDB0000517
chemical formula: C6H14N4O2
molecular weight: 174.11168
structure: ChemicalStructure/PW C000396

Acetyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Acetyl-CoA

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Succinic acid semialdehyde
type: SmallMolecule
cellular location: Cytosol
entity reference: Succinic acid semialdehyde

Reference/PubChem-compound 6992098
type: UnificationXref
id: 6992098
db: PubChem-compound

ornithine carbamoyltransferase
type: Complex
component stoichiometry: Protein/5869 Cytosol/Stoichiometry/3.0
component stoichiometry: Protein/5904 Cytosol/Stoichiometry/3.0
cellular location: Cytosol
component: Ornithine carbamoyltransferase chain F
component: Ornithine carbamoyltransferase chain I

N2-succinyl-L-arginine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58241
chemical formula: C10H17N4O5
molecular weight: 273.12045
structure: ChemicalStructure/PW C040856

N2-succinylglutamate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58763
chemical formula: C9H10NO7
molecular weight: 244.04738
structure: ChemicalStructure/PW C040857

4-(γ-glutamylamino)butanal
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 61508
chemical formula: C9H15N2O4
molecular weight: 215.10373
structure: ChemicalStructure/PW C040858

Compound/PW C000143 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C04133
type: UnificationXref
id: C04133
db: KEGG Compound

ReactionCatalysis2668
type: Catalysis
controller: acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase
controlled: 2.6.1.11
control type: ACTIVATION

Reference/ChEBI CHEBI 61508
type: UnificationXref
id: CHEBI:61508
db: ChEBI

ReactionCatalysis2669
type: Catalysis
controller: ornithine carbamoyltransferase
controlled: 2.1.3.3
control type: ACTIVATION

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Compound/PW C000849/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-Aminobutyraldehyde
stoichiometric coefficient: 1.0

ReactionCatalysis2664
type: Catalysis
controller: acetylglutamate kinase
controlled: 2.7.2.8
control type: ACTIVATION

ReactionCatalysis2663
type: Catalysis
controller: N-acetylglutamate synthase
controlled: Reaction2670
control type: ACTIVATION

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/PubChem-compound 440848
type: UnificationXref
id: 440848
db: PubChem-compound

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

ReactionCatalysis2677
type: Catalysis
controller: agmatinase
controlled: 3.5.3.11
control type: ACTIVATION

ReactionCatalysis2676
type: Catalysis
controller: arginine decarboxylase
controlled: 4.1.1.19
control type: ACTIVATION

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

ReactionCatalysis2679
type: Catalysis
controller: Gamma-glutamylputrescine oxidoreductase
controlled: 1.4.3.-
control type: ACTIVATION

ReactionCatalysis2678
type: Catalysis
controller: GLUTAMINE-PUTRESCINE LIGASE
controlled: 6.3.1.11
control type: ACTIVATION

L-Arginine
type: SmallMolecule
entity reference: L-Arginine

Compound/PW C000862 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbamoyl phosphate
stoichiometric coefficient: 1.0

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

ReactionCatalysis2671
type: Catalysis
controller: Arginine N-succinyltransferase
controlled: 2.3.1.109
control type: ACTIVATION

ReactionCatalysis2670
type: Catalysis
controller: carbamoyl phosphate synthetase
controlled: 6.3.5.5
control type: ACTIVATION

ReactionCatalysis2673
type: Catalysis
controller: succinylornithine transaminase
controlled: 2.6.1.81
control type: ACTIVATION

N-Acetyl-L-glutamyl 5-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: N-Acetyl-L-glutamyl 5-phosphate

ReactionCatalysis2672
type: Catalysis
controller: succinylarginine dihydrolase
controlled: 3.5.3.23
control type: ACTIVATION

ReactionCatalysis2675
type: Catalysis
controller: Succinylglutamate desuccinylase
controlled: 3.5.1.96
control type: ACTIVATION

ReactionCatalysis2674
type: Catalysis
controller: N-succinylglutamate 5-semialdehyde dehydrogenase
controlled: 1.2.1.71
control type: ACTIVATION

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/CAS 70-26-8
type: UnificationXref
id: 70-26-8
db: CAS

Ornithine carbamoyltransferase chain I
type: Protein
cellular location: Cytosol
entity reference: Ornithine carbamoyltransferase chain I

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/ChemSpider 6026
type: UnificationXref
id: 6026
db: ChemSpider

ReactionCatalysis2687
type: Catalysis
controller: acetylornithine deacetylase
controlled: Reaction2694
control type: ACTIVATION

Ornithine
type: SmallMolecule
entity reference: Ornithine

NADP
type: SmallMolecule
entity reference: NADP

ReactionCatalysis2680
type: Catalysis
controller: Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase
controlled: 1.2.1.5
control type: ACTIVATION

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

ReactionCatalysis2682
type: Catalysis
controller: Putrescine aminotransferase
controlled: 2.6.1.82
control type: ACTIVATION

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

ReactionCatalysis2681
type: Catalysis
controller: γ-glutamyl-γ-aminobutyrate hydrolase
controlled: 3.5.1.94
control type: ACTIVATION

ReactionCatalysis2684
type: Catalysis
controller: 4-aminobutyrate aminotransferase
controlled: 2.6.1.19
control type: ACTIVATION

ReactionCatalysis2683
type: Catalysis
controller: γ-aminobutyraldehyde dehydrogenase
controlled: 1.2.1.19
control type: ACTIVATION

ReactionCatalysis2686
type: Catalysis
controller: NAD+-dependent succinate semialdehyde dehydrogenase
controlled: 1.2.1.16
control type: ACTIVATION

Ornithine
type: SmallMoleculeReference
xref: Reference/CAS 70-26-8
xref: Reference/HMDB HMDB0000214
xref: Reference/PubChem-compound 6262
xref: Reference/KEGG Compound C00077
xref: Reference/BioCyc L-ORNITHINE
xref: Reference/ChemSpider 6026
xref: Reference/ChEBI CHEBI 15729
chemical formula: C5H12N2O2
molecular weight: 132.08987
structure: ChemicalStructure/PW C000140

ReactionCatalysis2685
type: Catalysis
controller: succinate-semialdehyde dehydrogenase (NADP+)
controlled: 1.2.1.79
control type: ACTIVATION

Reference/UniProt P0A6E4
type: UnificationXref
id: P0A6E4
db: UniProt

Reference/UniProt P11447
type: UnificationXref
id: P11447
db: UniProt

Reference/UniProt P11446
type: UnificationXref
id: P11446
db: UniProt

Gamma-glutamylputrescine synthetase
type: ProteinReference
xref: Reference/UniProt P78061

Ornithine carbamoyltransferase chain F
type: Protein
cellular location: Cytosol
entity reference: Ornithine carbamoyltransferase chain F

γ-Aminobutyric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: γ-Aminobutyric acid

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

agmatinase
type: Complex
component stoichiometry: Protein/6663 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Agmatinase

Reference/HMDB HMDB0000214
type: UnificationXref
id: HMDB0000214
db: HMDB

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Oxygen
type: SmallMolecule
entity reference: Oxygen

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/PathWhiz PW000779
type: UnificationXref
id: PW000779
db: PathWhiz

succinate-semialdehyde dehydrogenase (NADP+)
type: Complex
component stoichiometry: Protein/6444 Cytosol/Stoichiometry/4.0
cellular location: Cytosol
component: Succinate-semialdehyde dehydrogenase [NADP+]

Compound/PW C000940 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

ChemicalStructure/PW C000140
type: ChemicalStructure
structure format: SMILES
structure data: NCCC[C@H](N)C(O)=O

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc GLN
type: UnificationXref
id: GLN
db: BioCyc

Reference/PathWhiz PW000769
type: UnificationXref
id: PW000769
db: PathWhiz

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/UniProt P0A6F1
type: UnificationXref
id: P0A6F1
db: UniProt

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Compound/PW C000123/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartic acid
stoichiometric coefficient: 1.0

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Protein/6742/Stoichiometry/2.0
type: Stoichiometry
physical entity: N-succinylarginine dihydrolase
stoichiometric coefficient: 2.0

Protein/5986/Stoichiometry/4.0
type: Stoichiometry
physical entity: Argininosuccinate synthase
stoichiometric coefficient: 4.0

4-(γ-glutamylamino)butanal
type: SmallMolecule
entity reference: 4-(γ-glutamylamino)butanal

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

N2-succinyl-L-arginine
type: SmallMolecule
entity reference: N2-succinyl-L-arginine

Protein/6804/Stoichiometry/12.0
type: Stoichiometry
physical entity: Gamma-glutamylputrescine synthetase
stoichiometric coefficient: 12.0

N2-succinylglutamate
type: SmallMolecule
entity reference: N2-succinylglutamate

Reference/ChemSpider 116
type: UnificationXref
id: 116
db: ChemSpider

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Reference/ChemSpider 115
type: UnificationXref
id: 115
db: ChemSpider

Reference/ChemSpider 6082
type: UnificationXref
id: 6082
db: ChemSpider

ChemicalStructure/PW C002771
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)N[C@@H](CCC=O)C(O)=O

Reference/CAS 1188-37-0
type: UnificationXref
id: 1188-37-0
db: CAS

Succinic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000254
xref: Reference/CAS 110-15-6
xref: Reference/ChEBI CHEBI 15741
xref: Reference/KEGG Compound C00042
xref: Reference/ChemSpider 1078
xref: Reference/PubChem-compound 1110
xref: Reference/BioCyc SUC
chemical formula: C4H6O4
molecular weight: 118.02661
structure: ChemicalStructure/PW C000174

Reference/BioCyc CPD-569
type: UnificationXref
id: CPD-569
db: BioCyc

Carbamoyl-phosphate synthase small chain
type: ProteinReference
xref: Reference/UniProt P0A6F1

Argininosuccinate synthase
type: ProteinReference
xref: Reference/UniProt P0A6E4

Acetylglutamate kinase
type: ProteinReference
xref: Reference/UniProt P0A6C8

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

ReactionCatalysis2645
type: Catalysis
controller: Argininosuccinate lyase
controlled: 4.3.2.1
control type: ACTIVATION

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

ChemicalStructure/PW C000123
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC(O)=O)C(O)=O

ReactionCatalysis2642
type: Catalysis
controller: argininosuccinate synthase
controlled: Reaction2649
control type: ACTIVATION

Protein/6407/Stoichiometry/2.0
type: Stoichiometry
physical entity: 4-aminobutyrate aminotransferase
stoichiometric coefficient: 2.0

ChemicalStructure/PW C000723
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCCNC(N)=O)C(O)=O

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 15682
type: UnificationXref
id: CHEBI:15682
db: ChEBI

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

ChemicalStructure/PW C000972
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC=O

SubPathwayInteraction85074
type: Interaction
name: SubPathway85074Reaction
name: SubPathwayReaction
participant: Succinic acid

Reference/ChEBI CHEBI 16543
type: UnificationXref
id: CHEBI:16543
db: ChEBI

Protein/6475/Stoichiometry/10.0
type: Stoichiometry
physical entity: Biodegradative arginine decarboxylase
stoichiometric coefficient: 10.0

Reference/BioCyc CARBAMOYL-P
type: UnificationXref
id: CARBAMOYL-P
db: BioCyc

Putrescine aminotransferase
type: ProteinReference
xref: Reference/UniProt P42588

Compound/PW C000200 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Urea
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Putrescine
type: SmallMolecule
entity reference: Putrescine

Putrescine
type: SmallMoleculeReference
xref: Reference/CAS 110-60-1
xref: Reference/BioCyc PUTRESCINE
xref: Reference/ChEBI CHEBI 17148
xref: Reference/HMDB HMDB0001414
xref: Reference/ChemSpider 13837702
xref: Reference/KEGG Compound C00134
xref: Reference/PubChem-compound 1045
chemical formula: C4H12N2
molecular weight: 88.10005
structure: ChemicalStructure/PW C001092

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reaction2649
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000723/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000123/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000032/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000036/Stoichiometry/1.0
right: Adenosine monophosphate
right: Argininosuccinic acid
right: Pyrophosphate
spontaneous: false
left: L-Aspartic acid
left: Citrulline
left: Adenosine triphosphate
name: Adenosine triphosphate + Citrulline + L-Aspartic acid → Adenosine monophosphate + Argininosuccinic acid + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P0A6C8
type: UnificationXref
id: P0A6C8
db: UniProt

Escherichia coli
type: BioSource
xref: Reference/TAXONOMY 562

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

Reference/ChEBI CHEBI 27657
type: UnificationXref
id: CHEBI:27657
db: ChEBI

Protein/7202/Stoichiometry/2.0
type: Stoichiometry
physical entity: Aldehyde dehydrogenase-like protein yneI
stoichiometric coefficient: 2.0

Reference/UniProt P76149
type: UnificationXref
id: P76149
db: UniProt

Reference/KEGG Compound C00624
type: UnificationXref
id: C00624
db: KEGG Compound

4-aminobutyrate aminotransferase_
type: ProteinReference
xref: Reference/UniProt P50457

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Compound/PW C000095 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000790
type: UnificationXref
id: PW000790
db: PathWhiz

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Compound/PW C022608/Stoichiometry/2.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 2.0

Reference/UniProt P23883
type: UnificationXref
id: P23883
db: UniProt

Succinic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Succinic acid
name: SubPathwayInput

Reference/ChemSpider 113025
type: UnificationXref
id: 113025
db: ChemSpider

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc N-ALPHA-ACETYLORNITHINE
type: UnificationXref
id: N-ALPHA-ACETYLORNITHINE
db: BioCyc

4-aminobutyrate aminotransferase
type: ProteinReference
xref: Reference/UniProt P22256

Protein/5989/Stoichiometry/2.0
type: Stoichiometry
physical entity: Carbamoyl-phosphate synthase small chain
stoichiometric coefficient: 2.0

ChemicalStructure/PW C001856
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)N[C@@H](CCCN)C(O)=O

Compound/PW C000916/Stoichiometry/1.0
type: Stoichiometry
physical entity: N2-Succinyl-L-glutamic acid 5-semialdehyde
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/PubChem-compound 439232
type: UnificationXref
id: 439232
db: PubChem-compound

Reference/ChemSpider 171
type: UnificationXref
id: 171
db: ChemSpider

Reference/PubChem-compound 278
type: UnificationXref
id: 278
db: PubChem-compound

Reference/ChEBI CHEBI 16349
type: UnificationXref
id: CHEBI:16349
db: ChEBI

Succinyl-CoA
type: SmallMolecule
entity reference: Succinyl-CoA

Protein/5869 Cytosol/Stoichiometry/3.0
type: Stoichiometry
physical entity: Ornithine carbamoyltransferase chain I
stoichiometric coefficient: 3.0

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Reference/ChEBI CHEBI 17431
type: UnificationXref
id: CHEBI:17431
db: ChEBI

Reference/ChEBI CHEBI 17672
type: UnificationXref
id: CHEBI:17672
db: ChEBI

Reference/PubChem-compound 1045
type: UnificationXref
id: 1045
db: PubChem-compound

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Reference/UniProt P00968
type: UnificationXref
id: P00968
db: UniProt

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

4.3.2.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000396/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000088/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000036/Stoichiometry/1.0
right: Fumaric acid
right: L-Arginine
spontaneous: false
EC number: 4.3.2.1
left: Argininosuccinic acid
name: Argininosuccinic acid → Fumaric acid + L-Arginine
conversion direction: LEFT_TO_RIGHT

Protein/6790/Stoichiometry/2.0
type: Stoichiometry
physical entity: Succinylornithine transaminase
stoichiometric coefficient: 2.0

Reaction154145
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002771 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002749 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: N-Acetyl-L-glutamate 5-semialdehyde
right: NADP
spontaneous: false
left: Hydrogen Ion
left: N-Acetyl-L-glutamyl 5-phosphate
left: NADPH
name: Hydrogen Ion + N-Acetyl-L-glutamyl 5-phosphate + NADPH ? N-Acetyl-L-glutamate 5-semialdehyde + NADP + Phosphate

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

Acetylornithine deacetylase
type: ProteinReference
xref: Reference/UniProt P23908

Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase
type: ProteinReference
xref: Reference/UniProt P23883

ChemicalStructure/PW C000500
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(N)=O)C(O)=O

Agmatinase
type: ProteinReference
xref: Reference/UniProt P60651
organism: Escherichia coli

Reference/PubChem-compound 20841830
type: UnificationXref
id: 20841830
db: PubChem-compound

4.1.1.19
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000396/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001107/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Agmatine
right: Carbon dioxide
spontaneous: false
EC number: 4.1.1.19
left: L-Arginine
left: Hydrogen Ion
name: Hydrogen Ion + L-Arginine → Agmatine + Carbon dioxide
conversion direction: LEFT_TO_RIGHT

3.5.3.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001092 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001107 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000200 Cytosol/Stoichiometry/1.0
right: Urea
right: Putrescine
spontaneous: false
EC number: 3.5.3.11
left: Agmatine
left: Water
name: Agmatine + Water → Putrescine + Urea
conversion direction: LEFT_TO_RIGHT

1.2.1.71
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000916/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040857/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/2.0
right: NADH
right: Hydrogen Ion
right: N2-succinylglutamate
spontaneous: false
EC number: 1.2.1.71
left: N2-Succinyl-L-glutamic acid 5-semialdehyde
left: Water
left: NAD
name: N2-Succinyl-L-glutamic acid 5-semialdehyde + NAD + Water → N2-succinylglutamate + 2 Hydrogen Ion + NADH
conversion direction: LEFT_TO_RIGHT

3.5.1.96
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040857/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000174/Stoichiometry/1.0
right: Succinic acid
right: L-Glutamic acid
spontaneous: false
EC number: 3.5.1.96
left: Water
left: N2-succinylglutamate
name: N2-succinylglutamate + Water → L-Glutamic acid + Succinic acid
conversion direction: LEFT_TO_RIGHT

2.6.1.81
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000916/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000934/Stoichiometry/1.0
right: N2-Succinyl-L-glutamic acid 5-semialdehyde
right: L-Glutamic acid
spontaneous: false
EC number: 2.6.1.81
left: Oxoglutaric acid
left: N2-Succinyl-L-ornithine
name: N2-Succinyl-L-ornithine + Oxoglutaric acid → L-Glutamic acid + N2-Succinyl-L-glutamic acid 5-semialdehyde
conversion direction: LEFT_TO_RIGHT

Compound/PW C007776/Stoichiometry/1.0
type: Stoichiometry
physical entity: γ-glutamyl-L-putrescine
stoichiometric coefficient: 1.0

2.6.1.82
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001092/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000849/Stoichiometry/1.0
right: 4-Aminobutyraldehyde
right: L-Glutamic acid
spontaneous: false
EC number: 2.6.1.82
left: Oxoglutaric acid
left: Putrescine
name: Oxoglutaric acid + Putrescine → 4-Aminobutyraldehyde + L-Glutamic acid
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 194
type: UnificationXref
id: 194
db: ChemSpider

1.2.1.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040858/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007718/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/2.0
right: Hydrogen Ion
right: 4-(Glutamylamino) butanoate
right: NADPH
spontaneous: false
EC number: 1.2.1.5
left: Water
left: NADP
left: 4-(γ-glutamylamino)butanal
name: 4-(γ-glutamylamino)butanal + NADP + Water → 4-(Glutamylamino) butanoate + 2 Hydrogen Ion + NADPH
conversion direction: LEFT_TO_RIGHT

3.5.1.94
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007718 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000071 Cytosol/Stoichiometry/1.0
right: γ-Aminobutyric acid
right: L-Glutamic acid
spontaneous: false
EC number: 3.5.1.94
left: 4-(Glutamylamino) butanoate
left: Water
name: 4-(Glutamylamino) butanoate + Water → L-Glutamic acid + γ-Aminobutyric acid
conversion direction: LEFT_TO_RIGHT

6.3.1.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001092/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007776/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: γ-glutamyl-L-putrescine
right: Hydrogen Ion
right: Phosphate
spontaneous: false
EC number: 6.3.1.11
left: L-Glutamic acid
left: Putrescine
left: Adenosine triphosphate
name: Adenosine triphosphate + L-Glutamic acid + Putrescine → Adenosine diphosphate + Hydrogen Ion + Phosphate + γ-glutamyl-L-putrescine
conversion direction: LEFT_TO_RIGHT

1.4.3.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040858/Stoichiometry/1.0
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001783/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007776/Stoichiometry/1.0
right: Hydrogen peroxide
right: Ammonium
right: 4-(γ-glutamylamino)butanal
spontaneous: false
EC number: 1.4.3.-
left: γ-glutamyl-L-putrescine
left: Water
left: Oxygen
name: Oxygen + Water + γ-glutamyl-L-putrescine → 4-(γ-glutamylamino)butanal + Ammonium + Hydrogen peroxide
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P77674
type: UnificationXref
id: P77674
db: UniProt

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/PubChem-compound 440236
type: UnificationXref
id: 440236
db: PubChem-compound

Citrulline
type: SmallMolecule
cellular location: Cytosol
entity reference: Citrulline

Reaction2670
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000888/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Coenzyme A
right: Hydrogen Ion
right: N-Acetyl-L-glutamic acid
spontaneous: false
left: L-Glutamic acid
left: Acetyl-CoA
name: Acetyl-CoA + L-Glutamic acid → Coenzyme A + Hydrogen Ion + N-Acetyl-L-glutamic acid
conversion direction: LEFT_TO_RIGHT

2.7.2.8
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000888/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002749/Stoichiometry/1.0
right: Adenosine diphosphate
right: N-Acetyl-L-glutamyl 5-phosphate
spontaneous: false
EC number: 2.7.2.8
left: N-Acetyl-L-glutamic acid
left: Adenosine triphosphate
name: Adenosine triphosphate + N-Acetyl-L-glutamic acid → Adenosine diphosphate + N-Acetyl-L-glutamyl 5-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0000641
type: UnificationXref
id: HMDB0000641
db: HMDB

Reference/UniProt P42588
type: UnificationXref
id: P42588
db: UniProt

Reference/ChEBI CHEBI 16319
type: UnificationXref
id: CHEBI:16319
db: ChEBI

2.3.1.109
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000808/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000396/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040856/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Coenzyme A
right: Hydrogen Ion
right: N2-succinyl-L-arginine
spontaneous: false
EC number: 2.3.1.109
left: L-Arginine
left: Succinyl-CoA
name: L-Arginine + Succinyl-CoA → N2-succinyl-L-arginine + Coenzyme A + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc L-ORNITHINE
type: UnificationXref
id: L-ORNITHINE
db: BioCyc

3.5.3.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C022608/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040856/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000934/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/2.0
right: Ammonium
right: Carbon dioxide
right: N2-Succinyl-L-ornithine
spontaneous: false
EC number: 3.5.3.23
left: Water
left: Hydrogen Ion
left: N2-succinyl-L-arginine
name: N2-succinyl-L-arginine + 2 Hydrogen Ion + 2 Water → 2 Ammonium + Carbon dioxide + N2-Succinyl-L-ornithine
conversion direction: LEFT_TO_RIGHT

2.1.3.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000723 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000862 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000140 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Hydrogen Ion
right: Citrulline
spontaneous: false
EC number: 2.1.3.3
left: Carbamoyl phosphate
left: Ornithine
name: Carbamoyl phosphate + Ornithine → Citrulline + Hydrogen Ion + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 180
type: UnificationXref
id: 180
db: ChemSpider

6.3.5.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000463/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000500/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000862/Stoichiometry/1.0
right: Adenosine diphosphate
right: L-Glutamic acid
right: Hydrogen Ion
right: Carbamoyl phosphate
right: Phosphate
spontaneous: false
EC number: 6.3.5.5
left: Water
left: Hydrogen carbonate
left: L-Glutamine
left: Adenosine triphosphate
name: 2 Adenosine triphosphate + Hydrogen carbonate + L-Glutamine + Water → 2 Adenosine diphosphate + Carbamoyl phosphate + 2 Hydrogen Ion + L-Glutamic acid + Phosphate
conversion direction: LEFT_TO_RIGHT

2.6.1.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002771/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001856/Stoichiometry/1.0
right: Oxoglutaric acid
right: N-Acetylornithine
spontaneous: false
EC number: 2.6.1.11
left: N-Acetyl-L-glutamate 5-semialdehyde
left: L-Glutamic acid
name: L-Glutamic acid + N-Acetyl-L-glutamate 5-semialdehyde → N-Acetylornithine + Oxoglutaric acid
conversion direction: LEFT_TO_RIGHT