ReactionCoupledTransportCatalysis177
type: Catalysis
controller: NADH:ubiquinone oxidoreductase I
controlled: 1.6.99.5
control type: ACTIVATION

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

ReactionCoupledTransportCatalysis176
type: Catalysis
controller: cytochrome bo terminal oxidase
controlled: ReactionCoupledTransport142
control type: ACTIVATION

ReactionCoupledTransportCatalysis175
type: Catalysis
controller: cytochrome bd-II terminal oxidase
controlled: 1.10.3.10
control type: ACTIVATION

ReactionCoupledTransportCatalysis174
type: Catalysis
controller: cytochrome bd-I terminal oxidase
controlled: 1.10.3.14
control type: ACTIVATION

Succinic acid
type: SmallMolecule
entity reference: Succinic acid

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Reference/CAS 110-17-8
type: UnificationXref
id: 110-17-8
db: CAS

Reference/PubChem-compound 21883788
type: UnificationXref
id: 21883788
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Porphyrin Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway1502
pathway component: SubPathwayInteraction1502
xref: Reference/SMPDB SMP0000953
xref: Reference/PathWhiz PW000936
name: SubPathway

Compound/PW C001347 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Ubiquinone-1
stoichiometric coefficient: 2.0

NADH-quinone oxidoreductase subunit J
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit J

Reference/ChEBI CHEBI 16389
type: UnificationXref
id: CHEBI:16389
db: ChEBI

NADH-quinone oxidoreductase subunit F
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit F

Protein/7790/Stoichiometry/1.0
type: Stoichiometry
physical entity: succinate dehydrogenase
stoichiometric coefficient: 1.0

succinate dehydrogenase, FeS subunit
type: ProteinReference
xref: Reference/UniProt P07014

succinate:quinone oxidoreductase, FAD binding protein
type: ProteinReference
xref: Reference/UniProt P0AC41

Cytochrome o ubiquinol oxidase subunit 3
type: Protein
cellular location: Inner Membrane
entity reference: Cytochrome o ubiquinol oxidase subunit 3

cytochrome bd-I terminal oxidase - CydX subunit
type: Protein
cellular location: Inner Membrane
entity reference: cytochrome bd-I terminal oxidase - CydX subunit

Protein/7788/Stoichiometry/1.0
type: Stoichiometry
physical entity: succinate:quinone oxidoreductase, FAD binding protein
stoichiometric coefficient: 1.0

cytochrome bd-I terminal oxidase
type: Complex
cellular location: Inner Membrane
component: Cytochrome d ubiquinol oxidase subunit 2
component: Cytochrome d ubiquinol oxidase subunit 1
component: cytochrome bd-I terminal oxidase - CydX subunit

Protein/7791/Stoichiometry/1.0
type: Stoichiometry
physical entity: succinate dehydrogenase fumarate reductase, membrane anchor subunit
stoichiometric coefficient: 1.0

succinate dehydrogenase fumarate reductase, membrane anchor subunit
type: ProteinReference
xref: Reference/UniProt P0AC44

succinate dehydrogenase
type: ProteinReference
xref: Reference/UniProt P69054

Compound/PW C001065 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 1.0

NADH-quinone oxidoreductase subunit C/D
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit C/D

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/UniProt P0AC44
type: UnificationXref
id: P0AC44
db: UniProt

Cytochrome d ubiquinol oxidase subunit 2
type: Protein
cellular location: Inner Membrane
entity reference: Cytochrome d ubiquinol oxidase subunit 2

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

Compound/PW C001347 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ubiquinone-1
stoichiometric coefficient: 1.0

Reference/UniProt P0AC41
type: UnificationXref
id: P0AC41
db: UniProt

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/UniProt P33602
type: UnificationXref
id: P33602
db: UniProt

NAD
type: SmallMolecule
cellular location: Inner Membrane
entity reference: NAD

Ubiquinol oxidase subunit 2
type: Protein
cellular location: Inner Membrane
entity reference: Ubiquinol oxidase subunit 2

Ubiquinone-1
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16389
xref: Reference/ChemSpider 4307
xref: Reference/PubChem-compound 4462
xref: Reference/CAS 727-81-1
xref: Reference/HMDB HMDB0002012
xref: Reference/KEGG Compound C00399
chemical formula: C14H18O4
molecular weight: 250.12051
structure: ChemicalStructure/PW C001347

Ubiquinol-1
type: SmallMolecule
entity reference: Ubiquinol-1

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

Cytochrome o ubiquinol oxidase protein cyoD
type: ProteinReference
xref: Reference/UniProt P0ABJ6
organism: Escherichia coli

Reference/UniProt P33607
type: UnificationXref
id: P33607
db: UniProt

Cytochrome d ubiquinol oxidase subunit 2
type: ProteinReference
xref: Reference/UniProt P0ABK2
organism: Escherichia coli

Oxygen
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Oxygen

cytochrome bd-I terminal oxidase - CydX subunit
type: ProteinReference
xref: Reference/UniProt P56100
organism: Escherichia coli

NADH-quinone oxidoreductase subunit A
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit A

Ubiquinone-1
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Ubiquinone-1

Reference/UniProt P33599
type: UnificationXref
id: P33599
db: UniProt

Reference/UniProt P31979
type: UnificationXref
id: P31979
db: UniProt

ReactionCatalysis2607
type: Catalysis
controller: succinate:quinone oxidoreductase
controlled: Reaction2619
control type: ACTIVATION

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

Reference/UniProt P0AFE0
type: UnificationXref
id: P0AFE0
db: UniProt

Reference/BioCyc SUC
type: UnificationXref
id: SUC
db: BioCyc

Reference/UniProt P0AFD1
type: UnificationXref
id: P0AFD1
db: UniProt

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

cytochrome bd-II terminal oxidase
type: Complex
cellular location: Inner Membrane
component: Cytochrome bd-II oxidase subunit 1
component: Cytochrome bd-II oxidase subunit 2

Reference/UniProt P0AFD4
type: UnificationXref
id: P0AFD4
db: UniProt

Reference/UniProt P0AFD6
type: UnificationXref
id: P0AFD6
db: UniProt

Hydrogen Ion
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Hydrogen Ion

NADH
type: SmallMolecule
cellular location: Inner Membrane
entity reference: NADH

Reference/ChemSpider 4307
type: UnificationXref
id: 4307
db: ChemSpider

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Reference/KEGG Compound C00122
type: UnificationXref
id: C00122
db: KEGG Compound

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

ChemicalStructure/PW C001347
type: ChemicalStructure
structure format: SMILES
structure data: COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O

Ubiquinol oxidase subunit 1
type: ProteinReference
xref: Reference/UniProt P0ABI8
organism: Escherichia coli

Cytochrome bd-II oxidase subunit 1
type: Protein
cellular location: Inner Membrane
entity reference: Cytochrome bd-II oxidase subunit 1

Cytochrome bd-II oxidase subunit 2
type: Protein
cellular location: Inner Membrane
entity reference: Cytochrome bd-II oxidase subunit 2

Reference/UniProt P0AFF0
type: UnificationXref
id: P0AFF0
db: UniProt

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

NADH-quinone oxidoreductase subunit B
type: ProteinReference
xref: Reference/UniProt P0AFC7
organism: Escherichia coli

Compound/PW C040034 Inner Membrane/Stoichiometry/5.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 5.0

NADH-quinone oxidoreductase subunit A
type: ProteinReference
xref: Reference/UniProt P0AFC3
organism: Escherichia coli

Reference/UniProt P0AFE4
type: UnificationXref
id: P0AFE4
db: UniProt

Fumaric acid
type: SmallMolecule
entity reference: Fumaric acid

Reference/UniProt P0AFE8
type: UnificationXref
id: P0AFE8
db: UniProt

Fumaric acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000134
xref: Reference/ChemSpider 10197150
xref: Reference/CAS 110-17-8
xref: Reference/PubChem-compound 21883788
xref: Reference/KEGG Compound C00122
xref: Reference/BioCyc FUM
xref: Reference/ChEBI CHEBI 18012
chemical formula: C4H4O4
molecular weight: 116.010956
structure: ChemicalStructure/PW C000088

succinate:quinone oxidoreductase
type: Complex
component stoichiometry: Protein/7788/Stoichiometry/1.0
component stoichiometry: Protein/7791/Stoichiometry/1.0
component stoichiometry: Protein/7790/Stoichiometry/1.0
component stoichiometry: Protein/7789/Stoichiometry/1.0
component: succinate:quinone oxidoreductase, FAD binding protein
component: succinate dehydrogenase, FeS subunit
component: succinate dehydrogenase fumarate reductase, membrane anchor subunit
component: succinate dehydrogenase

Reference/ChEBI CHEBI 15741
type: UnificationXref
id: CHEBI:15741
db: ChEBI

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/PubChem-compound 447920
type: UnificationXref
id: 447920
db: PubChem-compound

Ubiquinol oxidase subunit 2
type: ProteinReference
xref: Reference/UniProt P0ABJ1
organism: Escherichia coli

NADH-quinone oxidoreductase subunit N
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit N

NADH-quinone oxidoreductase subunit K
type: ProteinReference
xref: Reference/UniProt P0AFE4
organism: Escherichia coli

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

NADH-quinone oxidoreductase subunit J
type: ProteinReference
xref: Reference/UniProt P0AFE0
organism: Escherichia coli

NADH-quinone oxidoreductase subunit I
type: ProteinReference
xref: Reference/UniProt P0AFD6
organism: Escherichia coli

Reference/PubChem-compound 1110
type: UnificationXref
id: 1110
db: PubChem-compound

NADH-quinone oxidoreductase subunit H
type: ProteinReference
xref: Reference/UniProt P0AFD4
organism: Escherichia coli

NADH-quinone oxidoreductase subunit I
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit I

NADH-quinone oxidoreductase subunit E
type: ProteinReference
xref: Reference/UniProt P0AFD1
organism: Escherichia coli

NADH-quinone oxidoreductase subunit N
type: ProteinReference
xref: Reference/UniProt P0AFF0
organism: Escherichia coli

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

NADH-quinone oxidoreductase subunit M
type: ProteinReference
xref: Reference/UniProt P0AFE8
organism: Escherichia coli

NADH-quinone oxidoreductase subunit B
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit B

Succinic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000254
xref: Reference/CAS 110-15-6
xref: Reference/ChEBI CHEBI 15741
xref: Reference/KEGG Compound C00042
xref: Reference/ChemSpider 1078
xref: Reference/PubChem-compound 1110
xref: Reference/BioCyc SUC
chemical formula: C4H6O4
molecular weight: 118.02661
structure: ChemicalStructure/PW C000174

Reference/TAXONOMY 562
type: UnificationXref
id: 562
db: TAXONOMY

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Compound/PW C042948 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Ubiquinol-1
stoichiometric coefficient: 2.0

Oxidative Phosphorylation
type: Pathway
pathway order: PathwayEnzymeReaction/6659
pathway order: PathwayEnzymeReaction/8419
pathway order: PathwayEnzymeReaction/6646
pathway order: PathwayEnzymeReaction/6662
pathway order: PathwaySubPathway/1502
pathway order: PathwayEnzymeReaction/6663
pathway component: Reaction2619
pathway component: ReactionCoupledTransportCatalysis177
pathway component: ReactionCatalysis2607
pathway component: ReactionCoupledTransportCatalysis176
pathway component: 1.6.99.5
pathway component: ReactionCoupledTransportCatalysis175
pathway component: Porphyrin Metabolism
pathway component: ReactionCoupledTransportCatalysis174
pathway component: 1.10.3.10
pathway component: ReactionCoupledTransport142
pathway component: 1.10.3.14
xref: Reference/SMPDB SMP0000936
xref: Reference/PathWhiz PW000919
organism: Escherichia coli

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Cytochrome bd-II oxidase subunit 2
type: ProteinReference
xref: Reference/UniProt P26458
organism: Escherichia coli

Compound/PW C040034 Inner Membrane/Stoichiometry/4.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 4.0

Reference/UniProt P56100
type: UnificationXref
id: P56100
db: UniProt

Compound/PW C042948/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ubiquinol-1
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00399
type: UnificationXref
id: C00399
db: KEGG Compound

Reference/UniProt P0ABI8
type: UnificationXref
id: P0ABI8
db: UniProt

Cytochrome d ubiquinol oxidase subunit 1
type: ProteinReference
xref: Reference/UniProt P0ABJ9
organism: Escherichia coli

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Reference/HMDB HMDB0000134
type: UnificationXref
id: HMDB0000134
db: HMDB

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000254
type: UnificationXref
id: HMDB0000254
db: HMDB

ChemicalStructure/PW C000174
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(O)=O

Reference/SMPDB SMP0000936
type: UnificationXref
id: SMP0000936
db: SMPDB

Compound/PW C042948 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ubiquinol-1
stoichiometric coefficient: 1.0

Reaction2619
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001347/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000174/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000088/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042948/Stoichiometry/1.0
right: Fumaric acid
right: Ubiquinol-1
spontaneous: false
left: Succinic acid
left: Ubiquinone-1
name: Succinic acid + Ubiquinone-1 → Fumaric acid + Ubiquinol-1
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P0ABJ1
type: UnificationXref
id: P0ABJ1
db: UniProt

Reference/UniProt P0ABJ3
type: UnificationXref
id: P0ABJ3
db: UniProt

NADH-quinone oxidoreductase subunit E
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit E

Reference/KEGG Compound C00042
type: UnificationXref
id: C00042
db: KEGG Compound

Reference/UniProt P0ABJ6
type: UnificationXref
id: P0ABJ6
db: UniProt

Reference/ChemSpider 1078
type: UnificationXref
id: 1078
db: ChemSpider

NADH:ubiquinone oxidoreductase I
type: Complex
cellular location: Inner Membrane
component: NADH-quinone oxidoreductase subunit A
component: NADH-quinone oxidoreductase subunit F
component: NADH-quinone oxidoreductase subunit L
component: NADH-quinone oxidoreductase subunit E
component: NADH-quinone oxidoreductase subunit N
component: NADH-quinone oxidoreductase subunit K
component: NADH-quinone oxidoreductase subunit I
component: NADH-quinone oxidoreductase subunit M
component: NADH-quinone oxidoreductase subunit G
component: NADH-quinone oxidoreductase subunit C/D
component: NADH-quinone oxidoreductase subunit B
component: NADH-quinone oxidoreductase subunit H
component: NADH-quinone oxidoreductase subunit J

Reference/UniProt P0ABJ9
type: UnificationXref
id: P0ABJ9
db: UniProt

Cytochrome bd-II oxidase subunit 1
type: ProteinReference
xref: Reference/UniProt P26459
organism: Escherichia coli

NADH-quinone oxidoreductase subunit M
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit M

Reference/UniProt P26459
type: UnificationXref
id: P26459
db: UniProt

Reference/UniProt P26458
type: UnificationXref
id: P26458
db: UniProt

1.6.99.5
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/5.0
participant stoichiometry: Compound/PW C042948 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001347 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Inner Membrane/Stoichiometry/1.0
right: NAD
right: Ubiquinol-1
right: Hydrogen Ion
spontaneous: false
EC number: 1.6.99.5
left: Ubiquinone-1
left: NADH
left: Hydrogen Ion
name: 5 Hydrogen Ion + NADH + Ubiquinone-1 → Hydrogen Ion + NAD + Ubiquinol-1
conversion direction: LEFT_TO_RIGHT

1.10.3.10
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/4.0
participant stoichiometry: Compound/PW C042948 Inner Membrane/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001065 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001347 Inner Membrane/Stoichiometry/2.0
right: Water
right: Ubiquinone-1
right: Hydrogen Ion
spontaneous: false
EC number: 1.10.3.10
left: Ubiquinol-1
left: Oxygen
left: Hydrogen Ion
name: 4 Hydrogen Ion + Oxygen + 2 Ubiquinol-1 → 4 Hydrogen Ion + 2 Ubiquinone-1 + 2 Water
conversion direction: LEFT_TO_RIGHT

ReactionCoupledTransport142
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C042948 Inner Membrane/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001065 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/8.0
participant stoichiometry: Compound/PW C001347 Inner Membrane/Stoichiometry/2.0
right: Water
right: Ubiquinone-1
right: Hydrogen Ion
spontaneous: false
left: Ubiquinol-1
left: Oxygen
left: Hydrogen Ion
name: 8 Hydrogen Ion + Oxygen + 2 Ubiquinol-1 → 8 Hydrogen Ion + 2 Ubiquinone-1 + 2 Water
conversion direction: LEFT_TO_RIGHT

1.10.3.14
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/4.0
participant stoichiometry: Compound/PW C042948 Inner Membrane/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001065 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001347 Inner Membrane/Stoichiometry/2.0
right: Water
right: Ubiquinone-1
right: Hydrogen Ion
spontaneous: false
EC number: 1.10.3.14
left: Ubiquinol-1
left: Oxygen
left: Hydrogen Ion
name: 4 Hydrogen Ion + Oxygen + 2 Ubiquinol-1 → 4 Hydrogen Ion + 2 Ubiquinone-1 + 2 Water
conversion direction: LEFT_TO_RIGHT

Water
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Water

Reference/ChemSpider 10197150
type: UnificationXref
id: 10197150
db: ChemSpider

NADH-quinone oxidoreductase subunit L
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit L

SubPathwayInteraction1502
type: Interaction
name: SubPathway1502Reaction
name: SubPathwayReaction

Reference/UniProt P0ABK2
type: UnificationXref
id: P0ABK2
db: UniProt

Reference/BioCyc FUM
type: UnificationXref
id: FUM
db: BioCyc

Escherichia coli
type: BioSource
xref: Reference/TAXONOMY 562

Reference/UniProt P69054
type: UnificationXref
id: P69054
db: UniProt

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

ChemicalStructure/PW C042948
type: ChemicalStructure
structure format: SMILES
structure data: COC1=C(O)C(C)=C(CC=C(C)C)C(O)=C1OC

Reference/ChEBI CHEBI 18012
type: UnificationXref
id: CHEBI:18012
db: ChEBI

Ubiquinol oxidase subunit 1
type: Protein
cellular location: Inner Membrane
entity reference: Ubiquinol oxidase subunit 1

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

cytochrome bo terminal oxidase
type: Complex
cellular location: Inner Membrane
component: Ubiquinol oxidase subunit 1
component: Ubiquinol oxidase subunit 2
component: Cytochrome o ubiquinol oxidase protein cyoD
component: Cytochrome o ubiquinol oxidase subunit 3

Reference/SMPDB SMP0000953
type: UnificationXref
id: SMP0000953
db: SMPDB

Compound/PW C001144 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

NADH-quinone oxidoreductase subunit F
type: ProteinReference
xref: Reference/UniProt P31979
organism: Escherichia coli

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

Reference/UniProt P0AFC3
type: UnificationXref
id: P0AFC3
db: UniProt

Reference/UniProt P0AFC7
type: UnificationXref
id: P0AFC7
db: UniProt

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Compound/PW C001347/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ubiquinone-1
stoichiometric coefficient: 1.0

Compound/PW C000174/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

Ubiquinol-1
type: SmallMoleculeReference
xref: Reference/PubChem-compound 447920
chemical formula: C14H20O4
molecular weight: 252.13615
structure: ChemicalStructure/PW C042948

Ubiquinone-1
type: SmallMolecule
entity reference: Ubiquinone-1

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/CAS 110-15-6
type: UnificationXref
id: 110-15-6
db: CAS

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

Compound/PW C001420 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 2.0

succinate:quinone oxidoreductase, FAD binding protein
type: Protein
entity reference: succinate:quinone oxidoreductase, FAD binding protein

succinate dehydrogenase, FeS subunit
type: Protein
entity reference: succinate dehydrogenase, FeS subunit

NADH-quinone oxidoreductase subunit G
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit G

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/PathWhiz PW000936
type: UnificationXref
id: PW000936
db: PathWhiz

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

succinate dehydrogenase fumarate reductase, membrane anchor subunit
type: Protein
entity reference: succinate dehydrogenase fumarate reductase, membrane anchor subunit

NADH-quinone oxidoreductase subunit H
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit H

succinate dehydrogenase
type: Protein
entity reference: succinate dehydrogenase

Reference/PubChem-compound 4462
type: UnificationXref
id: 4462
db: PubChem-compound

NADH-quinone oxidoreductase subunit L
type: ProteinReference
xref: Reference/UniProt P33607
organism: Escherichia coli

Cytochrome o ubiquinol oxidase subunit 3
type: ProteinReference
xref: Reference/UniProt P0ABJ3
organism: Escherichia coli

NADH-quinone oxidoreductase subunit K
type: Protein
cellular location: Inner Membrane
entity reference: NADH-quinone oxidoreductase subunit K

NADH-quinone oxidoreductase subunit G
type: ProteinReference
xref: Reference/UniProt P33602
organism: Escherichia coli

Compound/PW C040034 Inner Membrane/Stoichiometry/8.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 8.0

NADH-quinone oxidoreductase subunit C/D
type: ProteinReference
xref: Reference/UniProt P33599
organism: Escherichia coli

Reference/PathWhiz PW000919
type: UnificationXref
id: PW000919
db: PathWhiz

Reference/CAS 727-81-1
type: UnificationXref
id: 727-81-1
db: CAS

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Protein/7789/Stoichiometry/1.0
type: Stoichiometry
physical entity: succinate dehydrogenase, FeS subunit
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0002012
type: UnificationXref
id: HMDB0002012
db: HMDB

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Ubiquinol-1
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Ubiquinol-1

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/UniProt P07014
type: UnificationXref
id: P07014
db: UniProt

ChemicalStructure/PW C000088
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)\C=C\C(O)=O

Cytochrome d ubiquinol oxidase subunit 1
type: Protein
cellular location: Inner Membrane
entity reference: Cytochrome d ubiquinol oxidase subunit 1

Compound/PW C000088/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fumaric acid
stoichiometric coefficient: 1.0

Cytochrome o ubiquinol oxidase protein cyoD
type: Protein
cellular location: Inner Membrane
entity reference: Cytochrome o ubiquinol oxidase protein cyoD

Compound/PW C000721 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0