Reference/PathWhiz PW000981
type: UnificationXref
id: PW000981
db: PathWhiz

ChemicalStructure/PW C041557
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

2-Octaprenyl-6-hydroxyphenol
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1233
xref: Reference/PubChem-compound 5280833
chemical formula: C48H74
molecular weight: 650.57904
structure: ChemicalStructure/PW C041137

Reference/BioCyc CPD-9956
type: UnificationXref
id: CPD-9956
db: BioCyc

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/UniProt P0AGK1
type: UnificationXref
id: P0AGK1
db: UniProt

Reference/HMDB HMDB0012199
type: UnificationXref
id: HMDB0012199
db: HMDB

BiologicalState304
type: BioSource
xref: Reference/TAXONOMY 2
name: Bacteria

Compound/PW C001065/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 1.0

Reference/UniProt P25535
type: UnificationXref
id: P25535
db: UniProt

Reference/ChemSpider 132
type: UnificationXref
id: 132
db: ChemSpider

Reference/UniProt P25534
type: UnificationXref
id: P25534
db: UniProt

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/HMDB HMDB0001060
type: UnificationXref
id: HMDB0001060
db: HMDB

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

2-Octaprenylphenol
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5280832
xref: Reference/ChEBI CHEBI 40407
chemical formula: C46H70O
molecular weight: 638.54266
structure: ChemicalStructure/PW C041140

Reference/HMDB HMDB0001185
type: UnificationXref
id: HMDB0001185
db: HMDB

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Ubiquinol-8
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 61682
xref: Reference/PubChem-compound 22833558
xref: Reference/CAS 74075-00-6
xref: Reference/BioCyc CPD-9956
xref: Reference/ChemSpider 24603698
xref: Reference/HMDB HMDB0001060
chemical formula: C49H76O4
molecular weight: 728.57434
structure: ChemicalStructure/PW C000835

Reference/KEGG Compound C00448
type: UnificationXref
id: C00448
db: KEGG Compound

Reduced acceptor
type: SmallMolecule
entity reference: Reduced acceptor

Reference/UniProt P0AD57
type: UnificationXref
id: P0AD57
db: UniProt

Chorismate Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway109903
pathway component: SubPathwayInteraction109903
xref: Reference/SMPDB SMP0000836
xref: Reference/PathWhiz PW000816
name: SubPathway

Chorismate--pyruvate lyase
type: ProteinReference
xref: Reference/UniProt P26602

Compound/PW C000382/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-Hydroxybenzoic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 393270
type: UnificationXref
id: 393270
db: ChemSpider

Compound/PW C007748/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chorismate
stoichiometric coefficient: 1.0

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/ChEBI CHEBI 60655
type: UnificationXref
id: CHEBI:60655
db: ChEBI

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

Reference/ChEBI CHEBI 1617
type: UnificationXref
id: CHEBI:1617
db: ChEBI

S-Adenosylmethionine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 24762165
xref: Reference/KEGG Compound C00019
xref: Reference/ChemSpider 31983
xref: Reference/ChEBI CHEBI 15414
xref: Reference/CAS 485-80-3
xref: Reference/BioCyc S-ADENOSYLMETHIONINE
xref: Reference/HMDB HMDB0001185
chemical formula: C15H23N6O5S
molecular weight: 399.14505
structure: ChemicalStructure/PW C000921

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase
type: Protein
entity reference: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/ChemSpider 4444251
type: UnificationXref
id: 4444251
db: ChemSpider

Ubiquinol-8
type: SmallMolecule
entity reference: Ubiquinol-8
name: SubPathwayInput

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/ChEBI CHEBI 15022
type: UnificationXref
id: CHEBI:15022
db: ChEBI

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

ChemicalStructure/PW C007748
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Secondary Metabolites: Methylerythritol Phosphate and Polyisoprenoid Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway109905
pathway component: SubPathwayInteraction109905
xref: Reference/SMPDB SMP0000974
xref: Reference/PathWhiz PW000958
name: SubPathway

2.5.1.90
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000768 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000860 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytosol/Stoichiometry/5.0
participant stoichiometry: Compound/PW C001039 Cytosol/Stoichiometry/5.0
right: Pyrophosphate
right: Octaprenyl diphosphate
spontaneous: false
EC number: 2.5.1.90
left: Farnesyl pyrophosphate
left: Isopentenyl pyrophosphate
name: Farnesyl pyrophosphate + 5 Isopentenyl pyrophosphate → Octaprenyl diphosphate + 5 Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/PathWhiz PW000958
type: UnificationXref
id: PW000958
db: PathWhiz

Reference/PubChem-compound 135
type: UnificationXref
id: 135
db: PubChem-compound

2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol
type: SmallMolecule
entity reference: 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol

Reference/BioCyc ADENOSYL-HOMO-CYS
type: UnificationXref
id: ADENOSYL-HOMO-CYS
db: BioCyc

Pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyrophosphate

Reference/CAS 485-80-3
type: UnificationXref
id: 485-80-3
db: CAS

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/KEGG Compound C04146
type: UnificationXref
id: C04146
db: KEGG Compound

octaprenyl diphosphate synthase
type: Complex
component stoichiometry: Protein/7291 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Octaprenyl-diphosphate synthase

Reference/ChEBI CHEBI 17333
type: UnificationXref
id: CHEBI:17333
db: ChEBI

3-demethylubiquinol-8
type: SmallMolecule
entity reference: 3-demethylubiquinol-8

Reference/PubChem-compound 445713
type: UnificationXref
id: 445713
db: PubChem-compound

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

4-Hydroxybenzoic acid
type: SmallMolecule
entity reference: 4-Hydroxybenzoic acid

Reference/ChEBI CHEBI 30763
type: UnificationXref
id: CHEBI:30763
db: ChEBI

Compound/PW C042760/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-methoxy-6-(all-trans-octaprenyl)phenol
stoichiometric coefficient: 1.0

NADP
type: SmallMolecule
entity reference: NADP

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Octaprenyl diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Octaprenyl diphosphate

Reference/HMDB HMDB0001094
type: UnificationXref
id: HMDB0001094
db: HMDB

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

4-Hydroxybenzoic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 135
xref: Reference/ChEBI CHEBI 30763
xref: Reference/HMDB HMDB0000500
xref: Reference/CAS 99-96-7
xref: Reference/ChemSpider 132
xref: Reference/KEGG Compound C00156
chemical formula: C7H6O3
molecular weight: 138.0317
structure: ChemicalStructure/PW C000382

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

ChemicalStructure/PW C000921
type: ChemicalStructure
structure format: SMILES

Reference/CAS 979-92-0
type: UnificationXref
id: 979-92-0
db: CAS

Isopentenyl pyrophosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00129
xref: Reference/ChemSpider 1158
xref: Reference/PubChem-compound 1195
xref: Reference/CAS 358-71-4
xref: Reference/HMDB HMDB0001347
xref: Reference/ChEBI CHEBI 16584
chemical formula: C5H12O7P2
molecular weight: 246.00583
structure: ChemicalStructure/PW C001039

3-demethylubiquinone-9 3-methyltransferase
type: ProteinReference
xref: Reference/UniProt P17993

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

S-Adenosylhomocysteine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 25246222
xref: Reference/ChemSpider 388301
xref: Reference/BioCyc ADENOSYL-HOMO-CYS
xref: Reference/CAS 979-92-0
xref: Reference/KEGG Compound C00021
xref: Reference/ChEBI CHEBI 16680
xref: Reference/HMDB HMDB0000939
chemical formula: C14H20N6O5S
molecular weight: 384.12158
structure: ChemicalStructure/PW C000749

Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
type: ProteinReference
xref: Reference/UniProt P0A887

2-octaprenyl-6-methoxyphenol hydroxylase
type: Protein
entity reference: 2-octaprenyl-6-methoxyphenol hydroxylase

Reference/PubChem-compound 54685638
type: UnificationXref
id: 54685638
db: PubChem-compound

Reference/UniProt P0A887
type: UnificationXref
id: P0A887
db: UniProt

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Oxygen
type: SmallMolecule
entity reference: Oxygen

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/KEGG Compound C00129
type: UnificationXref
id: C00129
db: KEGG Compound

Reference/ChemSpider 1158
type: UnificationXref
id: 1158
db: ChemSpider

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Reference/ChEBI CHEBI 15414
type: UnificationXref
id: CHEBI:15414
db: ChEBI

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

oxidized electron acceptor
type: SmallMolecule
entity reference: oxidized electron acceptor

Reference/SMPDB SMP0000974
type: UnificationXref
id: SMP0000974
db: SMPDB

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Farnesyl pyrophosphate
type: SmallMolecule
entity reference: Farnesyl pyrophosphate
name: SubPathwayOutput

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

ChemicalStructure/PW C000382
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C1=CC=C(O)C=C1

3-octaprenyl-4-hydroxybenzoate carboxy-lyase
type: Protein
entity reference: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase

Compound/PW C000860 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Octaprenyl diphosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 61705
type: UnificationXref
id: CHEBI:61705
db: ChEBI

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Reference/KEGG Compound C00019
type: UnificationXref
id: C00019
db: KEGG Compound

Reference/CAS 74075-00-6
type: UnificationXref
id: 74075-00-6
db: CAS

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/BioCyc S-ADENOSYLMETHIONINE
type: UnificationXref
id: S-ADENOSYLMETHIONINE
db: BioCyc

Reference/KEGG Compound C00251
type: UnificationXref
id: C00251
db: KEGG Compound

Reference/ChEBI CHEBI 16275
type: UnificationXref
id: CHEBI:16275
db: ChEBI

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/UniProt P26602
type: UnificationXref
id: P26602
db: UniProt

2-Octaprenylphenol
type: SmallMolecule
entity reference: 2-Octaprenylphenol

Octaprenyl-diphosphate synthase
type: Protein
cellular location: Cytosol
entity reference: Octaprenyl-diphosphate synthase

Reference/TAXONOMY 562
type: UnificationXref
id: 562
db: TAXONOMY

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

2-Octaprenyl-6-hydroxyphenol
type: SmallMolecule
entity reference: 2-Octaprenyl-6-hydroxyphenol

Reference/ChemSpider 388301
type: UnificationXref
id: 388301
db: ChemSpider

S-Adenosylhomocysteine
type: SmallMolecule
entity reference: S-Adenosylhomocysteine

2-octaprenylphenol hydroxylase
type: ProteinReference
xref: Reference/UniProt P25535

Reference/SMPDB SMP0000997
type: UnificationXref
id: SMP0000997
db: SMPDB

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase
type: ProteinReference
xref: Reference/UniProt P75728

Oxidative Phosphorylation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway109904
pathway component: SubPathwayInteraction109904
xref: Reference/SMPDB SMP0000936
xref: Reference/PathWhiz PW000919
name: SubPathway

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/KEGG Compound C00021
type: UnificationXref
id: C00021
db: KEGG Compound

ChemicalStructure/PW C042759
type: ChemicalStructure
structure format: SMILES
structure data: COC1=C(O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)C\C=C(/C)CC=C(C)C)=C(C)C(O)=C1

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Octaprenyl diphosphate
type: SmallMolecule
entity reference: Octaprenyl diphosphate

Compound/PW C000921/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylmethionine
stoichiometric coefficient: 1.0

Octaprenyl diphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5280651
xref: Reference/HMDB HMDB0001094
xref: Reference/BioCyc OCTAPRENYL-DIPHOSPHATE
xref: Reference/KEGG Compound C04146
xref: Reference/ChEBI CHEBI 16275
xref: Reference/ChemSpider 4444251
chemical formula: C40H68O7P2
molecular weight: 722.44403
structure: ChemicalStructure/PW C000860

ChemicalStructure/PW C042760
type: ChemicalStructure
structure format: SMILES
structure data: COC1=CC=CC(C\C=C(/C)C\C=C(/C)C\C=C(/C)C\C=C(/C)C\C=C(/C)C\C=C(/C)C\C=C(/C)CC=C(C)C)=C1O

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Compound/PW C042944/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-demethylubiquinol-8
stoichiometric coefficient: 1.0

2.1.1.222
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042760/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041137/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: 2-methoxy-6-(all-trans-octaprenyl)phenol
right: Hydrogen Ion
spontaneous: false
EC number: 2.1.1.222
left: 2-Octaprenyl-6-hydroxyphenol
left: S-Adenosylmethionine
name: 2-Octaprenyl-6-hydroxyphenol + S-Adenosylmethionine → 2-methoxy-6-(all-trans-octaprenyl)phenol + Hydrogen Ion + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

1.14.13.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041140/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041137/Stoichiometry/1.0
right: 2-Octaprenyl-6-hydroxyphenol
right: Water
right: NADP
spontaneous: false
EC number: 1.14.13.-
left: Hydrogen Ion
left: Oxygen
left: 2-Octaprenylphenol
left: NADPH
name: 2-Octaprenylphenol + Hydrogen Ion + NADPH + Oxygen → 2-Octaprenyl-6-hydroxyphenol + NADP + Water
conversion direction: LEFT_TO_RIGHT

4.1.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041557/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041140/Stoichiometry/1.0
right: Carbon dioxide
right: 2-Octaprenylphenol
spontaneous: false
EC number: 4.1.1.-
left: 3-Octaprenyl-4-hydroxybenzoate
left: Hydrogen Ion
name: 3-Octaprenyl-4-hydroxybenzoate + Hydrogen Ion → 2-Octaprenylphenol + Carbon dioxide
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 24603698
type: UnificationXref
id: 24603698
db: ChemSpider

2.5.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000860/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041557/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000382/Stoichiometry/1.0
right: 3-Octaprenyl-4-hydroxybenzoate
right: Pyrophosphate
spontaneous: false
EC number: 2.5.1.-
left: 4-Hydroxybenzoic acid
left: Octaprenyl diphosphate
name: 4-Hydroxybenzoic acid + Octaprenyl diphosphate → 3-Octaprenyl-4-hydroxybenzoate + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 40407
type: UnificationXref
id: CHEBI:40407
db: ChEBI

Reference/CAS 372-97-4
type: UnificationXref
id: 372-97-4
db: CAS

Compound/PW C001039 Cytosol/Stoichiometry/5.0
type: Stoichiometry
physical entity: Isopentenyl pyrophosphate
stoichiometric coefficient: 5.0

Reference/KEGG Compound C00156
type: UnificationXref
id: C00156
db: KEGG Compound

Compound/PW C000835/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ubiquinol-8
stoichiometric coefficient: 1.0

2-octaprenyl-6-methoxyphenol hydroxylase
type: ProteinReference
xref: Reference/UniProt P25534

Water
type: SmallMolecule
entity reference: Water

Compound/PW C042943/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001347
type: UnificationXref
id: HMDB0001347
db: HMDB

Compound/Generic40/Stoichiometry/1.0
type: Stoichiometry
physical entity: Reduced acceptor
stoichiometric coefficient: 1.0

4.1.3.40
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007748/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000382/Stoichiometry/1.0
right: 4-Hydroxybenzoic acid
right: Pyruvic acid
spontaneous: false
EC number: 4.1.3.40
left: Chorismate
name: Chorismate → 4-Hydroxybenzoic acid + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

4-hydroxybenzoate octaprenyltransferase
type: Protein
entity reference: 4-hydroxybenzoate octaprenyltransferase

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/SMPDB SMP0000936
type: UnificationXref
id: SMP0000936
db: SMPDB

3-Octaprenyl-4-hydroxybenzoate
type: SmallMolecule
entity reference: 3-Octaprenyl-4-hydroxybenzoate

2-methoxy-6-(all-trans-octaprenyl)phenol
type: SmallMolecule
entity reference: 2-methoxy-6-(all-trans-octaprenyl)phenol

6-Methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol
type: SmallMoleculeReference
chemical formula: C46H70O3
molecular weight: 670.5325
structure: ChemicalStructure/PW C042759

Chorismate
type: SmallMoleculeReference
xref: Reference/CAS 617-12-9
xref: Reference/BioCyc CPD-9517
xref: Reference/KEGG Compound C00251
xref: Reference/PubChem-compound 12039
xref: Reference/ChEBI CHEBI 17333
xref: Reference/ChemSpider 11542
xref: Reference/HMDB HMDB0012199
chemical formula: C10H10O6
molecular weight: 226.04774
structure: ChemicalStructure/PW C007748

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/HMDB HMDB0000939
type: UnificationXref
id: HMDB0000939
db: HMDB

Reference/UniProt P17993
type: UnificationXref
id: P17993
db: UniProt

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000860
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 11542
type: UnificationXref
id: 11542
db: ChemSpider

2-methoxy-6-(all-trans-octaprenyl)phenol
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1235
chemical formula: C40H58O2
molecular weight: 570.44366
structure: ChemicalStructure/PW C042760

SubPathwayInteraction109904
type: Interaction
name: SubPathway109904Reaction
name: SubPathwayReaction
participant: Ubiquinol-8

ChemicalStructure/PW C042943
type: ChemicalStructure
structure format: SMILES

SubPathwayInteraction109903
type: Interaction
name: SubPathway109903Reaction
name: SubPathwayReaction
participant: Chorismate

ChemicalStructure/PW C042944
type: ChemicalStructure
structure format: SMILES

Farnesyl pyrophosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00448
xref: Reference/HMDB HMDB0000961
xref: Reference/ChemSpider 393270
xref: Reference/ChEBI CHEBI 17407
xref: Reference/CAS 372-97-4
xref: Reference/BioCyc FARNESYL-PP
xref: Reference/PubChem-compound 445713
chemical formula: C15H28O7P2
molecular weight: 382.13104
structure: ChemicalStructure/PW C000768

SubPathwayInteraction109905
type: Interaction
name: SubPathwayReaction
name: SubPathway109905Reaction
participant: Farnesyl pyrophosphate

3-Octaprenyl-4-hydroxybenzoate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1617
xref: Reference/PubChem-compound 54685638
chemical formula: C47H70O3
molecular weight: 682.5325
structure: ChemicalStructure/PW C041557

Escherichia coli
type: BioSource
xref: Reference/TAXONOMY 562

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Protein/6369/Stoichiometry/2.0
type: Stoichiometry
physical entity: 3-demethylubiquinone-9 3-methyltransferase
stoichiometric coefficient: 2.0

Reduced acceptor
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15022

Compound/PW C041140/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Octaprenylphenol
stoichiometric coefficient: 1.0

Chorismate
type: SmallMolecule
entity reference: Chorismate
name: SubPathwayOutput

3-octaprenyl-4-hydroxybenzoate carboxy-lyase
type: ProteinReference
xref: Reference/UniProt P0AAB4

3-octaprenyl-4-hydroxybenzoate carboxy-lyase
type: Complex
component stoichiometry: Protein/7277/Stoichiometry/6.0
component: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase

Reference/CAS 617-12-9
type: UnificationXref
id: 617-12-9
db: CAS

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/PubChem-compound 22833558
type: UnificationXref
id: 22833558
db: PubChem-compound

Isopentenyl pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Isopentenyl pyrophosphate

bifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase
type: Complex
component stoichiometry: Protein/6369/Stoichiometry/2.0
component: 3-demethylubiquinone-9 3-methyltransferase

Compound/PW C041137/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Octaprenyl-6-hydroxyphenol
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0000836
type: UnificationXref
id: SMP0000836
db: SMPDB

Reference/CAS 99-96-7
type: UnificationXref
id: 99-96-7
db: CAS

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/BioCyc FARNESYL-PP
type: UnificationXref
id: FARNESYL-PP
db: BioCyc

ChemicalStructure/PW C000835
type: ChemicalStructure
structure format: SMILES
structure data: COC1=C(OC)C(O)=C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)C(C)=C1O

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

Reference/UniProt P75728
type: UnificationXref
id: P75728
db: UniProt

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Reference/HMDB HMDB0000961
type: UnificationXref
id: HMDB0000961
db: HMDB

Reference/PubChem-compound 5280651
type: UnificationXref
id: 5280651
db: PubChem-compound

Compound/PW C000860/Stoichiometry/1.0
type: Stoichiometry
physical entity: Octaprenyl diphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 1233
type: UnificationXref
id: CHEBI:1233
db: ChEBI

Octaprenyl-diphosphate synthase
type: ProteinReference
xref: Reference/UniProt P0AD57
organism: BiologicalState304

Reference/ChEBI CHEBI 1235
type: UnificationXref
id: CHEBI:1235
db: ChEBI

Reaction3723
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042944/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000835/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: Hydrogen Ion
right: Ubiquinol-8
spontaneous: false
left: 3-demethylubiquinol-8
left: S-Adenosylmethionine
name: 3-demethylubiquinol-8 + S-Adenosylmethionine → Hydrogen Ion + S-Adenosylhomocysteine + Ubiquinol-8
conversion direction: LEFT_TO_RIGHT

1.14.13.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042759/Stoichiometry/1.0
participant stoichiometry: Compound/Generic227/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042944/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065/Stoichiometry/1.0
participant stoichiometry: Compound/Generic40/Stoichiometry/1.0
right: Water
right: oxidized electron acceptor
right: 3-demethylubiquinol-8
spontaneous: false
EC number: 1.14.13.-
left: Reduced acceptor
left: Oxygen
left: 6-Methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol
name: 6-Methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + Oxygen + Reduced acceptor → 3-demethylubiquinol-8 + Water + oxidized electron acceptor
conversion direction: LEFT_TO_RIGHT

2.1.1.163
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042759/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042943/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: Hydrogen Ion
right: 6-Methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol
spontaneous: false
EC number: 2.1.1.163
left: 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol
left: S-Adenosylmethionine
name: 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol + S-Adenosylmethionine → 6-Methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + Hydrogen Ion + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

1.14.13.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042760/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042943/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Water
right: 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol
right: NADP
spontaneous: false
EC number: 1.14.13.-
left: 2-methoxy-6-(all-trans-octaprenyl)phenol
left: Hydrogen Ion
left: Oxygen
left: NADPH
name: 2-methoxy-6-(all-trans-octaprenyl)phenol + Hydrogen Ion + NADPH + Oxygen → 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol + NADP + Water
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/BioCyc CPD-9517
type: UnificationXref
id: CPD-9517
db: BioCyc

Reference/ChemSpider 31983
type: UnificationXref
id: 31983
db: ChemSpider

Compound/Generic227/Stoichiometry/1.0
type: Stoichiometry
physical entity: oxidized electron acceptor
stoichiometric coefficient: 1.0

Reference/CAS 358-71-4
type: UnificationXref
id: 358-71-4
db: CAS

3-demethylubiquinol-8
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 61705
chemical formula: C48H74O4
molecular weight: 714.5587
structure: ChemicalStructure/PW C042944

Protein/7277/Stoichiometry/6.0
type: Stoichiometry
physical entity: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
stoichiometric coefficient: 6.0

2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 60655
chemical formula: C47H72O3
molecular weight: 684.54816
structure: ChemicalStructure/PW C042943

Compound/PW C000170 Cytosol/Stoichiometry/5.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 5.0

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

ChemicalStructure/PW C000768
type: ChemicalStructure
structure format: SMILES

Reference/UniProt P0AAB4
type: UnificationXref
id: P0AAB4
db: UniProt

4-hydroxybenzoate octaprenyltransferase
type: ProteinReference
xref: Reference/UniProt P0AGK1

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Protein/7291 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Octaprenyl-diphosphate synthase
stoichiometric coefficient: 2.0

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

Chorismate--pyruvate lyase
type: Protein
entity reference: Chorismate--pyruvate lyase

Secondary Metabolites: Ubiquinol Biosynthesis
type: Pathway
pathway order: PathwayEnzymeReaction/2122926
pathway order: PathwayEnzymeReaction/8011
pathway order: PathwayEnzymeReaction/8010
pathway order: PathwayEnzymeReaction/8009
pathway order: PathwayEnzymeReaction/8008
pathway order: PathwayEnzymeReaction/8007
pathway order: PathwaySubPathway/109903
pathway order: PathwayEnzymeReaction/8006
pathway order: PathwayEnzymeReaction/7993
pathway order: PathwayEnzymeReaction/7994
pathway order: PathwayEnzymeReaction/7991
pathway order: PathwaySubPathway/109905
pathway order: PathwaySubPathway/109904
pathway component: 2.1.1.222
pathway component: ReactionCatalysis3690
pathway component: 1.14.13.-
pathway component: Oxidative Phosphorylation
pathway component: 4.1.1.-
pathway component: Chorismate Biosynthesis
pathway component: 2.5.1.-
pathway component: ReactionCatalysis3688
pathway component: ReactionCatalysis3689
pathway component: 4.1.3.40
pathway component: ReactionCatalysis3693
pathway component: ReactionCatalysis3694
pathway component: ReactionCatalysis3691
pathway component: ReactionCatalysis3692
pathway component: Reaction3723
pathway component: Secondary Metabolites: Methylerythritol Phosphate and Polyisoprenoid Biosynthesis
pathway component: 2.1.1.163
pathway component: 2.5.1.90
pathway component: ReactionCatalysis3676
pathway component: ReactionCatalysis3695
pathway component: ReactionCatalysis3696
xref: Reference/PathWhiz PW000981
xref: Reference/SMPDB SMP0000997
organism: Escherichia coli

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/PathWhiz PW000816
type: UnificationXref
id: PW000816
db: PathWhiz

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Compound/PW C042759/Stoichiometry/1.0
type: Stoichiometry
physical entity: 6-Methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

S-Adenosylmethionine
type: SmallMolecule
entity reference: S-Adenosylmethionine

Reference/ChEBI CHEBI 16584
type: UnificationXref
id: CHEBI:16584
db: ChEBI

Reference/PubChem-compound 5280832
type: UnificationXref
id: 5280832
db: PubChem-compound

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000500
type: UnificationXref
id: HMDB0000500
db: HMDB

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

ReactionCatalysis3676
type: Catalysis
controller: octaprenyl diphosphate synthase
controlled: 2.5.1.90
control type: ACTIVATION

Reference/PubChem-compound 5280833
type: UnificationXref
id: 5280833
db: PubChem-compound

ChemicalStructure/PW C041137
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 61682
type: UnificationXref
id: CHEBI:61682
db: ChEBI

Reference/TAXONOMY 2
type: UnificationXref
id: 2
db: TAXONOMY

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/PubChem-compound 1195
type: UnificationXref
id: 1195
db: PubChem-compound

Reference/ChEBI CHEBI 17407
type: UnificationXref
id: CHEBI:17407
db: ChEBI

2-octaprenylphenol hydroxylase
type: Protein
entity reference: 2-octaprenylphenol hydroxylase

ChemicalStructure/PW C001039
type: ChemicalStructure
structure format: SMILES
structure data: CC(=C)CCOP(O)(=O)OP(O)(O)=O

ChemicalStructure/PW C000749
type: ChemicalStructure
structure format: SMILES

6-Methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol
type: SmallMolecule
entity reference: 6-Methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/PubChem-compound 25246222
type: UnificationXref
id: 25246222
db: PubChem-compound

Reference/PathWhiz PW000919
type: UnificationXref
id: PW000919
db: PathWhiz

ReactionCatalysis3688
type: Catalysis
controller: Chorismate--pyruvate lyase
controlled: 4.1.3.40
control type: ACTIVATION

ReactionCatalysis3689
type: Catalysis
controller: 4-hydroxybenzoate octaprenyltransferase
controlled: 2.5.1.-
control type: ACTIVATION

Compound/PW C000749/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylhomocysteine
stoichiometric coefficient: 1.0

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C041140
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Farnesyl pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Farnesyl pyrophosphate

Compound/PW C000768 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Farnesyl pyrophosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

ReactionCatalysis3690
type: Catalysis
controller: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
controlled: 4.1.1.-
control type: ACTIVATION

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

oxidized electron acceptor
type: SmallMoleculeReference

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/ChEBI CHEBI 16680
type: UnificationXref
id: CHEBI:16680
db: ChEBI

Reference/PubChem-compound 12039
type: UnificationXref
id: 12039
db: PubChem-compound

Reference/PubChem-compound 24762165
type: UnificationXref
id: 24762165
db: PubChem-compound

Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
type: Protein
entity reference: Ubiquinone/menaquinone biosynthesis methyltransferase ubiE

3-demethylubiquinone-9 3-methyltransferase
type: Protein
entity reference: 3-demethylubiquinone-9 3-methyltransferase

Compound/PW C041557/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Octaprenyl-4-hydroxybenzoate
stoichiometric coefficient: 1.0

ReactionCatalysis3693
type: Catalysis
controller: 2-octaprenyl-6-methoxyphenol hydroxylase
controlled: 1.14.13.-
control type: ACTIVATION

ReactionCatalysis3694
type: Catalysis
controller: Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
controlled: 2.1.1.163
control type: ACTIVATION

Reference/BioCyc OCTAPRENYL-DIPHOSPHATE
type: UnificationXref
id: OCTAPRENYL-DIPHOSPHATE
db: BioCyc

ReactionCatalysis3691
type: Catalysis
controller: 2-octaprenylphenol hydroxylase
controlled: 1.14.13.-
control type: ACTIVATION

ReactionCatalysis3692
type: Catalysis
controller: bifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase
controlled: 2.1.1.222
control type: ACTIVATION

ReactionCatalysis3695
type: Catalysis
controller: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase
controlled: 1.14.13.-
control type: ACTIVATION

ReactionCatalysis3696
type: Catalysis
controller: bifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase
controlled: Reaction3723
control type: ACTIVATION