Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Glutamate/aspartate transport system permease protein gltK
type: Protein
cellular location: Inner Membrane
entity reference: Glutamate/aspartate transport system permease protein gltK

Transport352
type: Transport
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000078 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000078 Cytosol/Stoichiometry/1.0
right: Glycine
right: Hydrogen Ion
spontaneous: false
left: Hydrogen Ion
left: Glycine
name: Glycine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol
conversion direction: LEFT_TO_RIGHT

2,2-Dichloroacetaldehyde
type: SmallMolecule
entity reference: 2,2-Dichloroacetaldehyde

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/PubChem-compound 923
type: UnificationXref
id: 923
db: PubChem-compound

ChemicalStructure/PW C000448
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CS)C(O)=O

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Glutamate--cysteine ligase
type: Protein
entity reference: Glutamate--cysteine ligase

Reference/BioCyc CYS
type: UnificationXref
id: CYS
db: BioCyc

Compound/PW C001847/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxidized glutathione
stoichiometric coefficient: 1.0

γ-Glutamylcysteine
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00669
xref: Reference/PubChem-compound 123938
xref: Reference/HMDB HMDB0001049
xref: Reference/ChemSpider 110467
xref: Reference/ChEBI CHEBI 17515
xref: Reference/CAS 636-58-8
xref: Reference/BioCyc L-GAMMA-GLUTAMYLCYSTEINE
chemical formula: C8H14N2O5S
molecular weight: 250.06235
structure: ChemicalStructure/PW C000826

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

ReactionCatalysis5366
type: Catalysis
controller: Glutathione S-transferase
controlled: Reaction5406
control type: ACTIVATION

ReactionCatalysis5369
type: Catalysis
controller: Glutathione S-transferase
controlled: Reaction5409
control type: ACTIVATION

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

1-Nitronaphthalene-5,6-oxide
type: SmallMolecule
entity reference: 1-Nitronaphthalene-5,6-oxide

1-Nitronaphthalene-7,8-oxide
type: SmallMolecule
entity reference: 1-Nitronaphthalene-7,8-oxide

1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
type: SmallMolecule
entity reference: 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene

ReactionCatalysis5372
type: Catalysis
controller: Glutathione S-transferase
controlled: Reaction5412
control type: ACTIVATION

1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
type: SmallMolecule
entity reference: 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene

1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
type: SmallMolecule
entity reference: 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene

1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
type: SmallMolecule
entity reference: 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

ChemicalStructure/PW C000458
type: ChemicalStructure
structure format: SMILES
structure data: [Na+]

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Glutamate/aspartate periplasmic-binding protein
type: Protein
cellular location: Inner Membrane
entity reference: Glutamate/aspartate periplasmic-binding protein

Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

ReactionCatalysis5375
type: Catalysis
controller: Glutathione S-transferase
controlled: Reaction5415
control type: ACTIVATION

Transport369
type: Transport
participant stoichiometry: Compound/PW C000095 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000458 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000458 Cytosol/Stoichiometry/1.0
right: Sodium
right: L-Glutamic acid
spontaneous: false
left: Sodium
left: L-Glutamic acid
name: L-Glutamic acid (→), Sodium (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol
conversion direction: LEFT_TO_RIGHT

1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
type: SmallMoleculeReference
xref: Reference/PubChem-compound 11954057
xref: Reference/HMDB HMDB0060326
chemical formula: C20H24N4O9S
molecular weight: 496.1264
structure: ChemicalStructure/PW C041154

1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
type: SmallMoleculeReference
xref: Reference/PubChem-compound 11954056
xref: Reference/HMDB HMDB0060327
chemical formula: C20H24N4O9S
molecular weight: 496.1264
structure: ChemicalStructure/PW C041155

1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
type: SmallMoleculeReference
xref: Reference/PubChem-compound 11954055
xref: Reference/HMDB HMDB0060329
chemical formula: C20H24N4O9S
molecular weight: 496.1264
structure: ChemicalStructure/PW C041156

1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0060330
xref: Reference/PubChem-compound 11954054
chemical formula: C20H24N4O9S
molecular weight: 496.1264
structure: ChemicalStructure/PW C041157

1-Nitronaphthalene-5,6-oxide
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0060331
xref: Reference/PubChem-compound 11954051
chemical formula: C10H7NO3
molecular weight: 189.04259
structure: ChemicalStructure/PW C041158

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

1-Nitronaphthalene-7,8-oxide
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0060332
xref: Reference/PubChem-compound 11954053
chemical formula: C10H7NO3
molecular weight: 189.04259
structure: ChemicalStructure/PW C041159

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Transport371
type: Transport
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Cytosol/Stoichiometry/1.0
right: Hydrogen Ion
right: L-Glutamic acid
spontaneous: false
left: Hydrogen Ion
left: L-Glutamic acid
name: Hydrogen Ion (→), L-Glutamic acid (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

glutamate / aspartate ABC transporter
type: Complex
cellular location: Inner Membrane
component: Glutamate/aspartate transport system permease protein gltK
component: Glutamate/aspartate transport ATP-binding protein gltL
component: Glutamate/aspartate periplasmic-binding protein
component: Glutamate/aspartate transport system permease protein gltJ

Glutamate/aspartate transport system permease protein gltJ
type: Protein
cellular location: Inner Membrane
entity reference: Glutamate/aspartate transport system permease protein gltJ

Reference/ChEBI CHEBI 17561
type: UnificationXref
id: CHEBI:17561
db: ChEBI

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/ChemSpider 950
type: UnificationXref
id: 950
db: ChemSpider

Glutathione Metabolism II
type: Pathway
pathway order: PathwayEnzymeReaction/20398
pathway order: PathwayEnzymeReaction/20399
pathway order: PathwayEnzymeReaction/20405
pathway order: PathwayEnzymeReaction/20438
pathway order: PathwayEnzymeReaction/20856
pathway order: PathwayEnzymeReaction/20435
pathway order: PathwayEnzymeReaction/20469
pathway order: PathwayEnzymeReaction/20400
pathway order: PathwayTransport/20407
pathway order: PathwayEnzymeReaction/20466
pathway order: PathwayEnzymeReaction/20401
pathway order: PathwayTransport/20406
pathway order: PathwayTransport/20408
pathway component: Transport352
pathway component: ReactionCoupledTransportCatalysis136
pathway component: Transport371
pathway component: ReactionCatalysis3028
pathway component: Reaction5415
pathway component: 1.8.1.7
pathway component: Reaction3054
pathway component: 6.3.2.3
pathway component: 6.3.2.2
pathway component: TransportCatalysis317
pathway component: TransportCatalysis315
pathway component: ReactionCatalysis5366
pathway component: ReactionCatalysis5465
pathway component: ReactionCatalysis3026
pathway component: ReactionCatalysis5369
pathway component: ReactionCatalysis3027
pathway component: TransportCatalysis298
pathway component: Reaction5412
pathway component: ReactionCatalysis5372
pathway component: Reaction5406
pathway component: Reaction5505
pathway component: Reaction5409
pathway component: ReactionCoupledTransport102
pathway component: ReactionCatalysis5375
pathway component: Transport369
xref: Reference/SMPDB SMP0001941
xref: Reference/PathWhiz PW001927
organism: Escherichia coli

Reference/PathWhiz PW001927
type: UnificationXref
id: PW001927
db: PathWhiz

ChemicalStructure/PW C041225
type: ChemicalStructure
structure format: SMILES

γ-Glutamylcysteine
type: SmallMolecule
entity reference: γ-Glutamylcysteine

Compound/PW C000448/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Cysteine
stoichiometric coefficient: 1.0

2,2-Dichloroacetaldehyde
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6576
chemical formula: C2H3Cl3
molecular weight: 131.93004
structure: ChemicalStructure/PW C043227

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

NADPH
type: SmallMolecule
entity reference: NADPH

Glutathione S-transferase
type: ProteinReference
xref: Reference/UniProt P0A9D2

Reference/PubChem-compound 5862
type: UnificationXref
id: 5862
db: PubChem-compound

Proton glutamate symport protein
type: ProteinReference
xref: Reference/UniProt P21345

Compound/PW C000078 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycine
stoichiometric coefficient: 1.0

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

Glutathione synthetase
type: Protein
entity reference: Glutathione synthetase

Reaction5505
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000080/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043227/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041225/Stoichiometry/1.0
right: S-(Formylmethyl)glutathione
spontaneous: false
left: 2,2-Dichloroacetaldehyde
left: Glutathione
name: 2,2-Dichloroacetaldehyde + Glutathione → S-(Formylmethyl)glutathione
conversion direction: LEFT_TO_RIGHT

NADP
type: SmallMolecule
entity reference: NADP

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Glutamate/aspartate transport ATP-binding protein gltL
type: Protein
cellular location: Inner Membrane
entity reference: Glutamate/aspartate transport ATP-binding protein gltL

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/BioCyc GLY
type: UnificationXref
id: GLY
db: BioCyc

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/PubChem-compound 11954074
type: UnificationXref
id: 11954074
db: PubChem-compound

Compound/PW C041155/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
stoichiometric coefficient: 1.0

ReactionCoupledTransportCatalysis136
type: Catalysis
controller: glutamate / aspartate ABC transporter
controlled: ReactionCoupledTransport102
control type: ACTIVATION

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 16856
type: UnificationXref
id: CHEBI:16856
db: ChEBI

Reference/PubChem-compound 124886
type: UnificationXref
id: 124886
db: PubChem-compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/HMDB HMDB0000574
type: UnificationXref
id: HMDB0000574
db: HMDB

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

ReactionCatalysis3028
type: Catalysis
controller: glutathione reductase
controlled: 1.8.1.7
control type: ACTIVATION

Reaction5415
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000080/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041159/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041157/Stoichiometry/1.0
right: 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
spontaneous: false
left: 1-Nitronaphthalene-7,8-oxide
left: Glutathione
name: 1-Nitronaphthalene-7,8-oxide + Glutathione → 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/HMDB HMDB0060507
type: UnificationXref
id: HMDB0060507
db: HMDB

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Glycine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000123
xref: Reference/BioCyc GLY
xref: Reference/ChemSpider 730
xref: Reference/PubChem-compound 5257127
xref: Reference/CAS 56-40-6
xref: Reference/ChEBI CHEBI 15428
xref: Reference/KEGG Compound C00037
chemical formula: C2H5NO2
molecular weight: 75.03203
structure: ChemicalStructure/PW C000078

ReactionCatalysis3026
type: Catalysis
controller: Glutamate--cysteine ligase
controlled: 6.3.2.2
control type: ACTIVATION

ReactionCatalysis3027
type: Catalysis
controller: glutathione synthetase
controlled: 6.3.2.3
control type: ACTIVATION

Hydrogen Ion
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Hydrogen Ion

Compound/PW C041154/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
stoichiometric coefficient: 1.0

Reaction5412
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000080/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041156/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041159/Stoichiometry/1.0
right: 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
spontaneous: false
left: 1-Nitronaphthalene-7,8-oxide
left: Glutathione
name: 1-Nitronaphthalene-7,8-oxide + Glutathione → 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/KEGG Compound C00127
type: UnificationXref
id: C00127
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

S-(Formylmethyl)glutathione
type: SmallMoleculeReference
xref: Reference/PubChem-compound 11954074
xref: Reference/HMDB HMDB0060507
chemical formula: C12H19N3O7S
molecular weight: 349.09436
structure: ChemicalStructure/PW C041225

a reduced glutaredoxin
type: SmallMolecule
entity reference: a reduced glutaredoxin

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/SMPDB SMP0001941
type: UnificationXref
id: SMP0001941
db: SMPDB

Glutamate--cysteine ligase
type: ProteinReference
xref: Reference/UniProt P0A6W9

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C01330
type: UnificationXref
id: C01330
db: KEGG Compound

Glutathione reductase
type: Protein
entity reference: Glutathione reductase

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Glutamate/aspartate transport ATP-binding protein gltL
type: ProteinReference
xref: Reference/UniProt P0AAG3
organism: Escherichia coli

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Oxidized glutathione
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003337
xref: Reference/PubChem-compound 5255796
xref: Reference/ChemSpider 950
xref: Reference/KEGG Compound C00127
xref: Reference/BioCyc OXIDIZED-GLUTATHIONE
xref: Reference/CAS 27025-41-8
xref: Reference/ChEBI CHEBI 17858
chemical formula: C20H32N6O12S2
molecular weight: 612.152
structure: ChemicalStructure/PW C001847

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/PubChem-compound 6576
type: UnificationXref
id: 6576
db: PubChem-compound

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

D-serine/D-alanine/glycine transporter
type: Protein
entity reference: D-serine/D-alanine/glycine transporter

Reference/PubChem-compound 5257127
type: UnificationXref
id: 5257127
db: PubChem-compound

Glutathione
type: SmallMoleculeReference
xref: Reference/CAS 70-18-8
xref: Reference/HMDB HMDB0000125
xref: Reference/BioCyc OXIDIZED-GLUTATHIONE
xref: Reference/KEGG Compound C00051
xref: Reference/ChEBI CHEBI 16856
xref: Reference/PubChem-compound 124886
xref: Reference/ChemSpider 111188
chemical formula: C10H17N3O6S
molecular weight: 307.0838
structure: ChemicalStructure/PW C000080

Reaction5406
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041158/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000080/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041154/Stoichiometry/1.0
right: 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
spontaneous: false
left: 1-Nitronaphthalene-5,6-oxide
left: Glutathione
name: 1-Nitronaphthalene-5,6-oxide + Glutathione → 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000588
type: UnificationXref
id: HMDB0000588
db: HMDB

Reaction5409
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041158/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000080/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041155/Stoichiometry/1.0
right: 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
spontaneous: false
left: 1-Nitronaphthalene-5,6-oxide
left: Glutathione
name: 1-Nitronaphthalene-5,6-oxide + Glutathione → 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

ReactionCoupledTransport102
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
right: Phosphate
right: L-Glutamic acid
right: Adenosine diphosphate
right: Hydrogen Ion
spontaneous: false
left: Water
left: Adenosine triphosphate
left: L-Glutamic acid
name: Adenosine triphosphate + L-Glutamic acid + Water → Adenosine diphosphate + Hydrogen Ion + L-Glutamic acid + Phosphate
conversion direction: LEFT_TO_RIGHT

Glutathione
type: SmallMolecule
entity reference: Glutathione

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Compound/PW C041158/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1-Nitronaphthalene-5,6-oxide
stoichiometric coefficient: 1.0

Reference/PubChem-compound 11954054
type: UnificationXref
id: 11954054
db: PubChem-compound

Reference/PubChem-compound 11954055
type: UnificationXref
id: 11954055
db: PubChem-compound

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/PubChem-compound 11954053
type: UnificationXref
id: 11954053
db: PubChem-compound

Reference/PubChem-compound 11954056
type: UnificationXref
id: 11954056
db: PubChem-compound

Reference/PubChem-compound 11954057
type: UnificationXref
id: 11954057
db: PubChem-compound

Oxidized glutathione
type: SmallMolecule
entity reference: Oxidized glutathione

Sodium/glutamate symport carrier protein
type: Protein
entity reference: Sodium/glutamate symport carrier protein

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/UniProt P0A6W9
type: UnificationXref
id: P0A6W9
db: UniProt

Glycine
type: SmallMolecule
entity reference: Glycine

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

ReactionCatalysis5465
type: Catalysis
controller: Glutathione S-transferase
controlled: Reaction5505
control type: ACTIVATION

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Compound/PW C000095 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Compound/PW C041225/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-(Formylmethyl)glutathione
stoichiometric coefficient: 1.0

Reference/TAXONOMY 562
type: UnificationXref
id: 562
db: TAXONOMY

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/ChemSpider 5653
type: UnificationXref
id: 5653
db: ChemSpider

Glutamate/aspartate periplasmic-binding protein
type: ProteinReference
xref: Reference/UniProt P37902
organism: Escherichia coli

L-Glutamic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Glutamic acid

Compound/PW C000458 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sodium
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Reference/HMDB HMDB0000123
type: UnificationXref
id: HMDB0000123
db: HMDB

Compound/Generic105/Stoichiometry/1.0
type: Stoichiometry
physical entity: a reduced glutaredoxin
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0000125
type: UnificationXref
id: HMDB0000125
db: HMDB

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 29101
type: UnificationXref
id: CHEBI:29101
db: ChEBI

Reference/CAS 70-18-8
type: UnificationXref
id: 70-18-8
db: CAS

ChemicalStructure/PW C041159
type: ChemicalStructure
structure format: SMILES
structure data: O=N(=O)C1=CC=CC2=C1C1OC1C=C2

ChemicalStructure/PW C041158
type: ChemicalStructure
structure format: SMILES
structure data: O=N(=O)C1=CC=CC2=C1C=CC1OC21

ChemicalStructure/PW C041157
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C041156
type: ChemicalStructure
structure format: SMILES

Compound/PW C000078/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycine
stoichiometric coefficient: 1.0

Reference/BioCyc OXIDIZED-GLUTATHIONE
type: UnificationXref
id: OXIDIZED-GLUTATHIONE
db: BioCyc

Compound/PW C000080/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glutathione
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine triphosphate

Reference/CAS 52-90-4
type: UnificationXref
id: 52-90-4
db: CAS

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/UniProt P0AAG3
type: UnificationXref
id: P0AAG3
db: UniProt

Reference/KEGG Compound C00037
type: UnificationXref
id: C00037
db: KEGG Compound

Reference/ChemSpider 899
type: UnificationXref
id: 899
db: ChemSpider

Glutathione synthetase
type: ProteinReference
xref: Reference/UniProt P04425

Reference/PubChem-compound 5255796
type: UnificationXref
id: 5255796
db: PubChem-compound

Reference/ChemSpider 110467
type: UnificationXref
id: 110467
db: ChemSpider

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Phosphate

Reference/UniProt P37902
type: UnificationXref
id: P37902
db: UniProt

Reference/ChEBI CHEBI 17515
type: UnificationXref
id: CHEBI:17515
db: ChEBI

ChemicalStructure/PW C043227
type: ChemicalStructure
structure format: SMILES
structure data: ClCC(Cl)Cl

Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

L-Cysteine
type: SmallMolecule
entity reference: L-Cysteine

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Reference/KEGG Compound C00051
type: UnificationXref
id: C00051
db: KEGG Compound

Reference/PubChem-compound 11954051
type: UnificationXref
id: 11954051
db: PubChem-compound

Reference/CAS 17341-25-2
type: UnificationXref
id: 17341-25-2
db: CAS

Water
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Water

S-(Formylmethyl)glutathione
type: SmallMolecule
entity reference: S-(Formylmethyl)glutathione

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Glutathione reductase
type: ProteinReference
xref: Reference/UniProt P06715

an oxidized glutaredoxin
type: Protein
entity reference: an oxidized glutaredoxin

Escherichia coli
type: BioSource
xref: Reference/TAXONOMY 562

Compound/PW C000080/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glutathione
stoichiometric coefficient: 2.0

ChemicalStructure/PW C000826
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

D-serine/D-alanine/glycine transporter
type: ProteinReference
xref: Reference/UniProt P0AAE1

Reference/PubChem-compound 123938
type: UnificationXref
id: 123938
db: PubChem-compound

1.8.1.7
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001847/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000080/Stoichiometry/2.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADP
right: Glutathione
spontaneous: false
EC number: 1.8.1.7
left: Hydrogen Ion
left: Oxidized glutathione
left: NADPH
name: Hydrogen Ion + NADPH + Oxidized glutathione → 2 Glutathione + NADP
conversion direction: LEFT_TO_RIGHT

Reaction3054
type: BiochemicalReaction
participant stoichiometry: Compound/Generic105/Stoichiometry/1.0
participant stoichiometry: Protein/Generic106/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000080/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001847/Stoichiometry/1.0
right: a reduced glutaredoxin
right: Oxidized glutathione
spontaneous: true
left: an oxidized glutaredoxin
left: Glutathione
name: 2 Glutathione + an oxidized glutaredoxin → Oxidized glutathione + a reduced glutaredoxin
conversion direction: LEFT_TO_RIGHT

6.3.2.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000078/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000080/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000826/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: Phosphate
right: Glutathione
spontaneous: false
EC number: 6.3.2.3
left: γ-Glutamylcysteine
left: Glycine
left: Adenosine triphosphate
name: Adenosine triphosphate + Glycine + γ-Glutamylcysteine → Adenosine diphosphate + Glutathione + Hydrogen Ion + Phosphate
conversion direction: LEFT_TO_RIGHT

6.3.2.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000448/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000826/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: γ-Glutamylcysteine
right: Hydrogen Ion
right: Phosphate
spontaneous: false
EC number: 6.3.2.2
left: L-Glutamic acid
left: L-Cysteine
left: Adenosine triphosphate
name: Adenosine triphosphate + L-Cysteine + L-Glutamic acid → Adenosine diphosphate + Hydrogen Ion + Phosphate + γ-Glutamylcysteine
conversion direction: LEFT_TO_RIGHT

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Compound/PW C041157/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
stoichiometric coefficient: 1.0

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

TransportCatalysis298
type: Catalysis
controller: D-serine/D-alanine/glycine transporter
controlled: Transport352
control type: ACTIVATION

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

Reference/UniProt P0AER3
type: UnificationXref
id: P0AER3
db: UniProt

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/ChEBI CHEBI 17858
type: UnificationXref
id: CHEBI:17858
db: ChEBI

Reference/UniProt P0AER5
type: UnificationXref
id: P0AER5
db: UniProt

Compound/PW C000095 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/UniProt P0AER8
type: UnificationXref
id: P0AER8
db: UniProt

Protein/6115/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glutathione S-transferase
stoichiometric coefficient: 2.0

Reference/CAS 56-40-6
type: UnificationXref
id: 56-40-6
db: CAS

Sodium/glutamate symport carrier protein
type: ProteinReference
xref: Reference/UniProt P0AER8

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Glutamate/aspartate transport system permease protein gltK
type: ProteinReference
xref: Reference/UniProt P0AER5
organism: Escherichia coli

L-Glutamic acid
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: L-Glutamic acid

Glutamate/aspartate transport system permease protein gltJ
type: ProteinReference
xref: Reference/UniProt P0AER3
organism: Escherichia coli

glutathione reductase
type: Complex
component stoichiometry: Protein/5899/Stoichiometry/2.0
component: Glutathione reductase

glutathione synthetase
type: Complex
component stoichiometry: Protein/5870/Stoichiometry/4.0
component: Glutathione synthetase

Reference/UniProt P21345
type: UnificationXref
id: P21345
db: UniProt

Compound/PW C041159/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1-Nitronaphthalene-7,8-oxide
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15428
type: UnificationXref
id: CHEBI:15428
db: ChEBI

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Glycine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Glycine

Reference/CAS 636-58-8
type: UnificationXref
id: 636-58-8
db: CAS

Sodium
type: SmallMolecule
cellular location: Cytosol
entity reference: Sodium

Compound/PW C000458 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sodium
stoichiometric coefficient: 1.0

Phosphate
type: SmallMolecule
entity reference: Phosphate

Compound/PW C000078 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycine
stoichiometric coefficient: 1.0

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/ChemSpider 730
type: UnificationXref
id: 730
db: ChemSpider

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Compound/PW C000095 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Protein/5870/Stoichiometry/4.0
type: Stoichiometry
physical entity: Glutathione synthetase
stoichiometric coefficient: 4.0

TransportCatalysis317
type: Catalysis
controller: Proton glutamate symport protein
controlled: Transport371
control type: ACTIVATION

TransportCatalysis315
type: Catalysis
controller: Sodium/glutamate symport carrier protein
controlled: Transport369
control type: ACTIVATION

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Sodium
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Sodium

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/UniProt P0A9D2
type: UnificationXref
id: P0A9D2
db: UniProt

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Protein/5899/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glutathione reductase
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0003337
type: UnificationXref
id: HMDB0003337
db: HMDB

Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C041156/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
stoichiometric coefficient: 1.0

Reference/ChemSpider 111188
type: UnificationXref
id: 111188
db: ChemSpider

Reference/HMDB HMDB0060330
type: UnificationXref
id: HMDB0060330
db: HMDB

Reference/HMDB HMDB0060332
type: UnificationXref
id: HMDB0060332
db: HMDB

L-Cysteine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000574
xref: Reference/CAS 52-90-4
xref: Reference/KEGG Compound C00097
xref: Reference/BioCyc CYS
xref: Reference/ChemSpider 5653
xref: Reference/PubChem-compound 5862
xref: Reference/ChEBI CHEBI 17561
chemical formula: C3H7NO2S
molecular weight: 121.01975
structure: ChemicalStructure/PW C000448

Reference/HMDB HMDB0060331
type: UnificationXref
id: HMDB0060331
db: HMDB

Reference/CAS 27025-41-8
type: UnificationXref
id: 27025-41-8
db: CAS

Reference/UniProt P0AAE1
type: UnificationXref
id: P0AAE1
db: UniProt

Reference/KEGG Compound C00097
type: UnificationXref
id: C00097
db: KEGG Compound

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Protein/Generic106/Stoichiometry/1.0
type: Stoichiometry
physical entity: an oxidized glutaredoxin
stoichiometric coefficient: 1.0

Glycine
type: SmallMolecule
cellular location: Cytosol
entity reference: Glycine

Reference/HMDB HMDB0001049
type: UnificationXref
id: HMDB0001049
db: HMDB

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Proton glutamate symport protein
type: Protein
entity reference: Proton glutamate symport protein

ChemicalStructure/PW C000078
type: ChemicalStructure
structure format: SMILES
structure data: NCC(O)=O

Glutathione S-transferase
type: Protein
entity reference: Glutathione S-transferase

Reference/UniProt P06715
type: UnificationXref
id: P06715
db: UniProt

Reference/HMDB HMDB0060327
type: UnificationXref
id: HMDB0060327
db: HMDB

Reference/HMDB HMDB0060326
type: UnificationXref
id: HMDB0060326
db: HMDB

Reference/HMDB HMDB0060329
type: UnificationXref
id: HMDB0060329
db: HMDB

Reference/KEGG Compound C00669
type: UnificationXref
id: C00669
db: KEGG Compound

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Sodium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000588
xref: Reference/PubChem-compound 923
xref: Reference/KEGG Compound C01330
xref: Reference/ChEBI CHEBI 29101
xref: Reference/ChemSpider 899
xref: Reference/CAS 17341-25-2
chemical formula: Na
molecular weight: 22.989769
structure: ChemicalStructure/PW C000458

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000826/Stoichiometry/1.0
type: Stoichiometry
physical entity: γ-Glutamylcysteine
stoichiometric coefficient: 1.0

a reduced glutaredoxin
type: SmallMoleculeReference

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

L-Glutamic acid
type: SmallMolecule
cellular location: Inner Membrane
entity reference: L-Glutamic acid

Reference/BioCyc L-GAMMA-GLUTAMYLCYSTEINE
type: UnificationXref
id: L-GAMMA-GLUTAMYLCYSTEINE
db: BioCyc

an oxidized glutaredoxin
type: ProteinReference

Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001847
type: ChemicalStructure
structure format: SMILES

Glutathione S-transferase
type: Complex
component stoichiometry: Protein/6115/Stoichiometry/2.0
component: Glutathione S-transferase

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000080
type: ChemicalStructure
structure format: SMILES

Adenosine diphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine diphosphate

Reference/UniProt P04425
type: UnificationXref
id: P04425
db: UniProt

ChemicalStructure/PW C041155
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C041154
type: ChemicalStructure
structure format: SMILES

Compound/PW C043227/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2,2-Dichloroacetaldehyde
stoichiometric coefficient: 1.0

Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0