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  <cached-name>Guanine and Guanosine Salvage</cached-name>
  <cached-description>Guanosine can be converted into guanine through a phosphate driven guanosine phosphorylase resulting in the release of an alpha-D-ribose 1 phosphate and a guanine. This compound in turn reacts with a PRPP through a guanine phosphoribosyltransferase resulting in the release of a pyrophosphate and a GMP.
Guanosine can also react with and ATP driven guanosine kinase resulting in the release of an ADP, s hydrogen ion and a GMP
</cached-description>
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          <description>Guanosine can be converted into guanine through a phosphate driven guanosine phosphorylase resulting in the release of an alpha-D-ribose 1 phosphate and a guanine. This compound in turn reacts with a PRPP through a guanine phosphoribosyltransferase resulting in the release of a pyrophosphate and a GMP.
Guanosine can also react with and ATP driven guanosine kinase resulting in the release of an ADP, s hydrogen ion and a GMP
</description>
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              <text>Combes A, Lafleuriel J, Le Floc'h F: The inosine-guanosine kinase activity of mitochondria in tubers of Jerusalem artichoke. Plant Physiology &amp; Biochemistry. 1989;27(5):729-736.</text>
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              <text>Kawasaki H, Shimaoka M, Usuda Y, Utagawa T: End-product regulation and kinetic mechanism of guanosine-inosine kinase from Escherichia coli. Biosci Biotechnol Biochem. 2000 May;64(5):972-9.</text>
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              <pubmed-id>4563984</pubmed-id>
              <text>Gots JS, Benson CE, Shumas SR: Genetic separation of hypoxanthine and guanine-xanthine phosphoribosyltransferase activities by deletion mutations in Salmonella typhimurium. J Bacteriol. 1972 Nov;112(2):910-6.</text>
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              <pubmed-id>7007809</pubmed-id>
              <text>Hammer-Jespersen K, Buxton RS, Hansen TD: A second purine nucleoside phosphorylase in Escherichia coli K-12. II. Properties of xanthosine phosphorylase and its induction by xanthosine. Mol Gen Genet. 1980;179(2):341-8.</text>
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              <element-type>Pathway</element-type>
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              <pubmed-id nil="true"/>
              <text>Escherichia coli and Salmonella: Cellular and Molecular Biology (EcoSal). Online edition.</text>
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            <ontology-id>CL:0000000</ontology-id>
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            <name>Platelet </name>
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          <cell-type>
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            <name>Hepatocyte</name>
            <ontology-id>CL:0000182</ontology-id>
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          <cell-type>
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            <name>Neuron</name>
            <ontology-id>CL:0000540</ontology-id>
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          <cell-type>
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            <name>Cardiomyocyte</name>
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            <name>Beta cell</name>
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          <cell-type>
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            <name>Epithelial Cell</name>
            <ontology-id>CL:0000066</ontology-id>
          </cell-type>
          <cell-type>
            <id type="integer">12</id>
            <name>Astrocyte</name>
            <ontology-id>CL:0000127</ontology-id>
          </cell-type>
        </cell-types>
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            <name>Homo sapiens</name>
            <taxonomy-id>9606</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Human</common-name>
            <gram-stain nil="true"/>
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          <species>
            <id type="integer">3</id>
            <name>Escherichia coli</name>
            <taxonomy-id>562</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name></common-name>
            <gram-stain>negative</gram-stain>
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            <name>Saccharomyces cerevisiae</name>
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            <classification>Eukaryote</classification>
            <common-name>Yeast</common-name>
            <gram-stain>negative</gram-stain>
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          <species>
            <id type="integer">12</id>
            <name>Mus musculus</name>
            <taxonomy-id>10090</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Mouse</common-name>
            <gram-stain nil="true"/>
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            <name>Bos taurus</name>
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            <classification>Eukaryote</classification>
            <common-name>Cattle</common-name>
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            <name>Rattus norvegicus</name>
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            <common-name>Rat</common-name>
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          <species>
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            <name>Bacteria</name>
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            <classification>Prokaryote</classification>
            <common-name>Bacteria</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
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            <name>Schizosaccharomyces pombe</name>
            <taxonomy-id>4896</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name></common-name>
            <gram-stain>positive</gram-stain>
          </species>
          <species>
            <id type="integer">24</id>
            <name>Solanum lycopersicum</name>
            <taxonomy-id>4081</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Tomato</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">4</id>
            <name>Arabidopsis thaliana</name>
            <taxonomy-id>3702</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Thale cress</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">21</id>
            <name>Xenopus laevis</name>
            <taxonomy-id>8355</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>African clawed frog</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">6</id>
            <name>Caenorhabditis elegans</name>
            <taxonomy-id>6239</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Roundworm</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">25</id>
            <name>Escherichia coli (strain K12)</name>
            <taxonomy-id>83333</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain nil="true"/>
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          <species>
            <id type="integer">49</id>
            <name>Bathymodiolus platifrons</name>
            <taxonomy-id>220390</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Deep sea mussel</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">23</id>
            <name>Pseudomonas aeruginosa</name>
            <taxonomy-id>287</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name></common-name>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">60</id>
            <name>Nitzschia sp.</name>
            <taxonomy-id>0001</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Nitzschia4</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">10</id>
            <name>Drosophila melanogaster</name>
            <taxonomy-id>7227</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Fruit fly</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">202</id>
            <name>Spathaspora passalidarum</name>
            <taxonomy-id>340170</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Spathaspora passalidarum</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">29</id>
            <name>Saccharomyces cerevisiae (strain ATCC 204508 / S288c)</name>
            <taxonomy-id>559292</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Baker's yeast</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">51</id>
            <name>Picea sitchensis</name>
            <taxonomy-id>3332</taxonomy-id>
            <classification>Eukaryote</classification>
            <common-name>Sitka spruce</common-name>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">346</id>
            <name>Escherichia coli K-12</name>
            <taxonomy-id>679895</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name>E. coli K-12</common-name>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">26</id>
            <name>Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)</name>
            <taxonomy-id>481805</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">76</id>
            <name>Escherichia coli DORA_B_14</name>
            <taxonomy-id>1403944</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">77</id>
            <name>Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)</name>
            <taxonomy-id>199310</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">335</id>
            <name>Escherichia coli O157:H7</name>
            <taxonomy-id>83334</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1156</id>
            <name>Escherichia coli 536</name>
            <taxonomy-id>362663</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1157</id>
            <name>Escherichia coli APEC O1</name>
            <taxonomy-id>405955</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1158</id>
            <name>Escherichia coli E24377A</name>
            <taxonomy-id>331111</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1155</id>
            <name>Escherichia coli O157:H7 str. Sakai</name>
            <taxonomy-id>386585</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1162</id>
            <name>Escherichia coli O127:H6 str. E2348/69</name>
            <taxonomy-id>574521</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1159</id>
            <name>Escherichia coli HS</name>
            <taxonomy-id>331112</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1161</id>
            <name>Escherichia coli O157:H7 str. EC4115</name>
            <taxonomy-id>444450</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1160</id>
            <name>Escherichia coli str. K-12 substr. DH10B</name>
            <taxonomy-id>316385</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1163</id>
            <name>Escherichia coli UMN026</name>
            <taxonomy-id>585056</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1165</id>
            <name>Escherichia coli IAI1</name>
            <taxonomy-id>585034</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1166</id>
            <name>Escherichia coli S88</name>
            <taxonomy-id>585035</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1168</id>
            <name>Escherichia coli IAI39</name>
            <taxonomy-id>585057</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1167</id>
            <name>Escherichia coli ED1a</name>
            <taxonomy-id>585397</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1169</id>
            <name>Escherichia coli O157:H7 str. TW14359</name>
            <taxonomy-id>544404</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1170</id>
            <name>Escherichia coli O103:H2 str. 12009</name>
            <taxonomy-id>585395</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1171</id>
            <name>Escherichia coli O26:H11 str. 11368</name>
            <taxonomy-id>573235</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1172</id>
            <name>Escherichia coli O111:H- str. 11128</name>
            <taxonomy-id>585396</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1240</id>
            <name>Escherichia coli 042</name>
            <taxonomy-id>216592</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1241</id>
            <name>Escherichia coli W</name>
            <taxonomy-id>566546</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1243</id>
            <name>Escherichia coli IHE3034</name>
            <taxonomy-id>714962</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1258</id>
            <name>Escherichia coli DH1</name>
            <taxonomy-id>536056</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">33</id>
            <name>Escherichia coli (strain SE11)</name>
            <taxonomy-id>409438</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">34</id>
            <name>Escherichia coli (strain K12 / MC4100 / BW2952)</name>
            <taxonomy-id>595496</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">35</id>
            <name>Escherichia coli (strain ATCC 55124 / KO11)</name>
            <taxonomy-id>595495</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">36</id>
            <name>Escherichia coli (strain B / REL606)</name>
            <taxonomy-id>413997</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">37</id>
            <name>Escherichia coli (strain B / BL21-DE3)</name>
            <taxonomy-id>469008</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">39</id>
            <name>Escherichia coli (strain MS 21-1)</name>
            <taxonomy-id>749527</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">1173</id>
            <name>Escherichia coli O55:H7 str. CB9615</name>
            <taxonomy-id>701177</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">462</id>
            <name>Escherichia coli SE15</name>
            <taxonomy-id>431946</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">2466</id>
            <name>Escherichia coli O113:H21</name>
            <taxonomy-id>1078021</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain nil="true"/>
          </species>
          <species>
            <id type="integer">27</id>
            <name>Escherichia coli (strain SMS-3-5 / SECEC)</name>
            <taxonomy-id>439855</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
          <species>
            <id type="integer">255</id>
            <name>Escherichia coli str. K-12 substr. MG1655</name>
            <taxonomy-id>511145</taxonomy-id>
            <classification>Prokaryote</classification>
            <common-name nil="true"/>
            <gram-stain>negative</gram-stain>
          </species>
        </species>
        <subcellular-locations>
          <subcellular-location>
            <id type="integer">5</id>
            <name>Cytoplasm</name>
            <ontology-id>GO:0005737</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">31</id>
            <name>Periplasmic Space</name>
            <ontology-id>GO:0005620</ontology-id>
          </subcellular-location>
          <subcellular-location>
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            <name>Cytosol</name>
            <ontology-id>GO:0005829</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">3</id>
            <name>Mitochondrial Matrix</name>
            <ontology-id>GO:0005759</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">14</id>
            <name>Mitochondrial Outer Membrane</name>
            <ontology-id>GO:0005741</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">2</id>
            <name>Mitochondrion</name>
            <ontology-id>GO:0005739</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">15</id>
            <name>Nucleus</name>
            <ontology-id>GO:0005634</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">4</id>
            <name>Peroxisome</name>
            <ontology-id>GO:0005777</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">13</id>
            <name>Endoplasmic Reticulum</name>
            <ontology-id>GO:0005783</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">7</id>
            <name>Endoplasmic Reticulum Membrane</name>
            <ontology-id>GO:0005789</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">10</id>
            <name>Cell Membrane</name>
            <ontology-id>GO:0005886</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">27</id>
            <name>Peroxisome Membrane</name>
            <ontology-id>GO:0005778</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">11</id>
            <name>Extracellular Space</name>
            <ontology-id>GO:0005615</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">35</id>
            <name>Chloroplast</name>
            <ontology-id>GO:0009507</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">12</id>
            <name>Mitochondrial Inner Membrane</name>
            <ontology-id>GO:0005743</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">32</id>
            <name>Inner Membrane</name>
            <ontology-id>GO:0070258</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">19</id>
            <name>Sarcoplasmic Reticulum</name>
            <ontology-id>GO:0016529</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">24</id>
            <name>Mitochondrial Intermembrane Space</name>
            <ontology-id>GO:0005758</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">36</id>
            <name>Membrane</name>
            <ontology-id>GO:0016020</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">53</id>
            <name>Endoplasmic Reticulum Body</name>
            <ontology-id>GO:0010168</ontology-id>
          </subcellular-location>
          <subcellular-location>
            <id type="integer">34</id>
            <name>Plant-Type Vacuole</name>
            <ontology-id>GO:0000325</ontology-id>
          </subcellular-location>
        </subcellular-locations>
        <tissues>
          <tissue>
            <id type="integer">2</id>
            <name>Endothelium </name>
            <ontology-id>BTO:0000393</ontology-id>
            <visualization-template-id type="integer" nil="true"/>
            <drawable-image-id type="integer" nil="true"/>
          </tissue>
          <tissue>
            <id type="integer">1</id>
            <name>Liver</name>
            <ontology-id>BTO:0000759</ontology-id>
            <visualization-template-id type="integer">72</visualization-template-id>
            <drawable-image-id type="integer">9</drawable-image-id>
          </tissue>
          <tissue>
            <id type="integer">7</id>
            <name>Nervous System</name>
            <ontology-id>BTO:0001484</ontology-id>
            <visualization-template-id type="integer" nil="true"/>
            <drawable-image-id type="integer" nil="true"/>
          </tissue>
          <tissue>
            <id type="integer">18</id>
            <name>Pancreas</name>
            <ontology-id>BTO:0000988</ontology-id>
            <visualization-template-id type="integer" nil="true"/>
            <drawable-image-id type="integer" nil="true"/>
          </tissue>
          <tissue>
            <id type="integer">25</id>
            <name>Intestine</name>
            <ontology-id>BTO:0000648</ontology-id>
            <visualization-template-id type="integer" nil="true"/>
            <drawable-image-id type="integer" nil="true"/>
          </tissue>
          <tissue>
            <id type="integer">8</id>
            <name>Blood Vessel</name>
            <ontology-id>BTO:0001102</ontology-id>
            <visualization-template-id type="integer">74</visualization-template-id>
            <drawable-image-id type="integer">11</drawable-image-id>
          </tissue>
          <tissue>
            <id type="integer">28</id>
            <name>Stomach</name>
            <ontology-id>BTO:0001307</ontology-id>
            <visualization-template-id type="integer">155</visualization-template-id>
            <drawable-image-id type="integer">26</drawable-image-id>
          </tissue>
          <tissue>
            <id type="integer">24</id>
            <name>Brain</name>
            <ontology-id>BTO:0000142</ontology-id>
            <visualization-template-id type="integer">89</visualization-template-id>
            <drawable-image-id type="integer">16</drawable-image-id>
          </tissue>
        </tissues>
        <biological-states>
          <biological-state>
            <id type="integer">8</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">5</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000008</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">107</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">31</subcellular-location-id>
            <species-id type="integer">3</species-id>
            <cell-type-id type="integer" nil="true"/>
            <pwbs-id>PW_BS000107</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">108</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">1</subcellular-location-id>
            <species-id type="integer">3</species-id>
            <cell-type-id type="integer" nil="true"/>
            <pwbs-id>PW_BS000108</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">198</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">5</subcellular-location-id>
            <species-id type="integer">18</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000024</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">111</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">5</subcellular-location-id>
            <species-id type="integer">12</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000111</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">122</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">5</subcellular-location-id>
            <species-id type="integer">5</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000122</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">135</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">5</subcellular-location-id>
            <species-id type="integer">17</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000135</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">2</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">1</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000002</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">4</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">3</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000004</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">16</id>
            <tissue-id type="integer">2</tissue-id>
            <subcellular-location-id type="integer" nil="true"/>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">2</cell-type-id>
            <pwbs-id>PW_BS000016</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">22</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">14</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000022</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">13</id>
            <tissue-id type="integer">1</tissue-id>
            <subcellular-location-id type="integer">2</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer" nil="true"/>
            <pwbs-id>PW_BS000013</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">32</id>
            <tissue-id type="integer">1</tissue-id>
            <subcellular-location-id type="integer">15</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">5</cell-type-id>
            <pwbs-id>PW_BS000032</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">5</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">4</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000005</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">39</id>
            <tissue-id type="integer">7</tissue-id>
            <subcellular-location-id type="integer">1</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">3</cell-type-id>
            <pwbs-id>PW_BS000039</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">3</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">2</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000003</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">18</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">13</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000018</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">10</id>
            <tissue-id type="integer">1</tissue-id>
            <subcellular-location-id type="integer">7</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000010</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">49</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">7</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000049</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">14</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">10</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer" nil="true"/>
            <pwbs-id>PW_BS000014</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">58</id>
            <tissue-id type="integer">1</tissue-id>
            <subcellular-location-id type="integer">14</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000058</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">59</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">27</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000059</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">27</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">15</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer" nil="true"/>
            <pwbs-id>PW_BS000027</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">46</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">1</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">4</cell-type-id>
            <pwbs-id>PW_BS000046</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">29</id>
            <tissue-id type="integer">1</tissue-id>
            <subcellular-location-id type="integer" nil="true"/>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000029</pwbs-id>
          </biological-state>
          <biological-state>
            <id type="integer">66</id>
            <tissue-id type="integer">18</tissue-id>
            <subcellular-location-id type="integer">5</subcellular-location-id>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">8</cell-type-id>
            <pwbs-id>PW_BS000066</pwbs-id>
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          <biological-state>
            <id type="integer">72</id>
            <tissue-id type="integer" nil="true"/>
            <subcellular-location-id type="integer">5</subcellular-location-id>
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            <cell-type-id type="integer">3</cell-type-id>
            <pwbs-id>PW_BS000072</pwbs-id>
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          <biological-state>
            <id type="integer">61</id>
            <tissue-id type="integer">25</tissue-id>
            <subcellular-location-id type="integer" nil="true"/>
            <species-id type="integer">1</species-id>
            <cell-type-id type="integer">7</cell-type-id>
            <pwbs-id>PW_BS000061</pwbs-id>
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          <biological-state>
            <id type="integer">51</id>
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            <subcellular-location-id type="integer" nil="true"/>
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            <cell-type-id type="integer" nil="true"/>
            <pwbs-id>PW_BS000051</pwbs-id>
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          <biological-state>
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            <subcellular-location-id type="integer">15</subcellular-location-id>
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            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000023</pwbs-id>
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          <biological-state>
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            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000031</pwbs-id>
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          <biological-state>
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            <cell-type-id type="integer">1</cell-type-id>
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          <biological-state>
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          <biological-state>
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          <biological-state>
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            <cell-type-id type="integer">5</cell-type-id>
            <pwbs-id>PW_BS000026</pwbs-id>
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          <biological-state>
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            <pwbs-id>PW_BS000007</pwbs-id>
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          <biological-state>
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            <subcellular-location-id type="integer">5</subcellular-location-id>
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            <cell-type-id type="integer">1</cell-type-id>
            <pwbs-id>PW_BS000097</pwbs-id>
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          <biological-state>
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            <pwbs-id>PW_BS000100</pwbs-id>
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          <biological-state>
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          <biological-state>
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            <pwbs-id>PW_BS000101</pwbs-id>
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          <biological-state>
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          <biological-state>
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          <biological-state>
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        </biological-states>
        <bounds>
        </bounds>
        <compounds>
          <compound>
            <id type="integer">87</id>
            <name>Guanosine</name>
            <hmdb-id>HMDB0000133</hmdb-id>
            <description>Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a beta-N9-glycosidic bond. Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate), and GTP (guanosine triphosphate) (Wikipedia). This nucleoside exerts important neuroprotective and neuromodulator roles in the central nervous system, which may be related to inhibition of the glutamatergic neurotransmission activity. Guanosine is the specific extracellular guanine-based purines effector and its conversion occurs not only in the central nervous system but also peripherally (PMID: 16325434). Guanosine is found to be associated with purine nucleoside phosphorylase (PNP) deficiency, which is an inborn error of metabolism.</description>
            <cas>118-00-3</cas>
            <kegg-id>C00387</kegg-id>
            <pubchem-cid>6802</pubchem-cid>
            <chebi-id>16750</chebi-id>
            <biocyc-id>GUANOSINE</biocyc-id>
            <chemspider-id>6544</chemspider-id>
            <drugbank-id>DB02857</drugbank-id>
            <moldb-smiles>NC1=NC2=C(N=CN2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)N1</moldb-smiles>
            <moldb-formula>C10H13N5O5</moldb-formula>
            <moldb-inchi>InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1</moldb-inchi>
            <moldb-inchikey>NYHBQMYGNKIUIF-UUOKFMHZSA-N</moldb-inchikey>
            <moldb-iupac nil="true"/>
            <moldb-average-mass>283.2407</moldb-average-mass>
            <moldb-mono-mass>283.091668551</moldb-mono-mass>
            <moldb-alogps-logs nil="true"/>
            <moldb-donor-count nil="true"/>
            <moldb-traditional-iupac nil="true"/>
            <moldb-formal-charge type="integer" nil="true"/>
            <moldb-physiological-charge type="integer" nil="true"/>
            <drugbank-metabolite-id nil="true"/>
            <foodb-id>FDB003632</foodb-id>
            <synonyms>2-amino-1,9-dihydro-9-b-d-ribofuranosyl-6h-purin-6-one;2-amino-1,9-dihydro-9-beta-delta-ribofuranosyl-6h-purin-6-one;2-amino-inosine;9-b-d-ribofuranosyl-guanine;9-beta-delta-ribofuranosyl-guanine;Guanosine;Ribonucleoside;Vernine;B-d-ribofuranoside guanine-9;Beta-delta-ribofuranoside guanine-9;2(3h)-imino-9-beta-d-ribofuranosyl-9h-purin-6(1h)-one;2-amino-1,9-dihydro-9-beta-d-ribofuranosyl-6h-purin-6-one;2-amino-9-beta-d-ribofuranosyl-1,9-dihydro-6h-purin-6-one;9-beta-d-ribofuranosyl-guanine;G;Guanine riboside;Guanine-9-beta-d-ribofuranoside;Guanosin;Guo;2(3h)-imino-9-b-d-ribofuranosyl-9h-purin-6(1h)-one;2(3h)-imino-9-β-d-ribofuranosyl-9h-purin-6(1h)-one;2-amino-1,9-dihydro-9-β-d-ribofuranosyl-6h-purin-6-one;2-amino-9-b-d-ribofuranosyl-1,9-dihydro-6h-purin-6-one;2-amino-9-β-d-ribofuranosyl-1,9-dihydro-6h-purin-6-one;9-β-d-ribofuranosyl-guanine;Guanine-9-b-d-ribofuranoside;Guanine-9-β-d-ribofuranoside</synonyms>
            <pwc-id>PW_C000087</pwc-id>
            <short-name>Guo</short-name>
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                <biological-state-id type="integer">8</biological-state-id>
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                <biological-state-id type="integer">107</biological-state-id>
              </element-state>
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                <biological-state-id type="integer">108</biological-state-id>
              </element-state>
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                <biological-state-id type="integer">198</biological-state-id>
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              <element-state>
                <id type="integer">78675</id>
                <biological-state-id type="integer">111</biological-state-id>
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                <id type="integer">121863</id>
                <biological-state-id type="integer">122</biological-state-id>
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                <id type="integer">124416</id>
                <biological-state-id type="integer">135</biological-state-id>
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          <compound>
            <id type="integer">414</id>
            <name>Adenosine triphosphate</name>
            <hmdb-id>HMDB0000538</hmdb-id>
            <description>Adenosine triphosphate (ATP) is a nucleotide consisting of a purine base (adenine) attached to the first carbon atom of ribose (a pentose sugar). Three phosphate groups are esterified at the fifth carbon atom of the ribose. ATP is incorporated into nucleic acids by polymerases in the processes of DNA replication and transcription. ATP contributes to cellular energy charge and participates in overall energy balance, maintaining cellular homeostasis. ATP can act as an extracellular signaling molecule via interactions with specific purinergic receptors to mediate a wide variety of processes as diverse as neurotransmission, inflammation, apoptosis, and bone remodelling. Extracellular ATP and its metabolite adenosine have also been shown to exert a variety of effects on nearly every cell type in human skin, and ATP seems to play a direct role in triggering skin inflammatory, regenerative, and fibrotic responses to mechanical injury, an indirect role in melanocyte proliferation and apoptosis, and a complex role in Langerhans cell-directed adaptive immunity. During exercise, intracellular homeostasis depends on the matching of adenosine triphosphate (ATP) supply and ATP demand. Metabolites play a useful role in communicating the extent of ATP demand to the metabolic supply pathways. Effects as different as proliferation or differentiation, chemotaxis, release of cytokines or lysosomal constituents, and generation of reactive oxygen or nitrogen species are elicited upon stimulation of blood cells with extracellular ATP. The increased concentration of adenosine triphosphate (ATP) in erythrocytes from patients with chronic renal failure (CRF) has been observed in many studies but the mechanism leading to these abnormalities still is controversial. (PMID: 15490415, 15129319, 14707763, 14696970, 11157473).</description>
            <cas>56-65-5</cas>
            <kegg-id>C00002</kegg-id>
            <pubchem-cid>5957</pubchem-cid>
            <chebi-id>15422</chebi-id>
            <biocyc-id>ATP</biocyc-id>
            <chemspider-id>5742</chemspider-id>
            <drugbank-id>DB00171</drugbank-id>
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            <moldb-formula>C10H16N5O13P3</moldb-formula>
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            <description>Adenosine diphosphate, abbreviated ADP, is a nucleotide. It is an ester of pyrophosphoric acid with the nucleotide adenine. ADP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. ADP is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases.</description>
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            <pwc-id>PW_C001034</pwc-id>
            <short-name>ADP</short-name>
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            <name>Guanosine monophosphate</name>
            <hmdb-id>HMDB0001397</hmdb-id>
            <description>Guanosine monophosphate, also known as guanylic acid or 5'-GMP, belongs to the class of organic compounds known as purine ribonucleoside monophosphates. These are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached. Guanosine monophosphate is slightly soluble (in water) and a moderately acidic compound (based on its pKa). Guanosine monophosphate has been found throughout most human tissues, and has also been detected in multiple biofluids, such as saliva and blood. Guanosine monophosphate can be found anywhere throughout the human cell, such as in mitochondria, golgi, lysosome, and nucleus. Guanosine monophosphate exists in all living organisms, ranging from bacteria to humans. In humans, guanosine monophosphate is involved in the tigecycline action pathway, the homocarnosinosis pathway, the chloramphenicol action pathway, and the azithromycin action pathway. Guanosine monophosphate is also involved in several metabolic disorders, some of which include adenylosuccinate lyase deficiency, xanthine dehydrogenase deficiency (xanthinuria), adenine phosphoribosyltransferase deficiency (aprt), and myoadenylate deaminase deficiency. Outside of the human body, guanosine monophosphate can be found in a number of food items such as black salsify, oyster mushroom, endive, and redcurrant. This makes guanosine monophosphate a potential biomarker for the consumption of these food products. Guanosine 5\'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.</description>
            <cas>85-32-5</cas>
            <kegg-id>C00144</kegg-id>
            <pubchem-cid>6804</pubchem-cid>
            <chebi-id>17345</chebi-id>
            <biocyc-id>GMP</biocyc-id>
            <chemspider-id>6545</chemspider-id>
            <drugbank-id>DB01972</drugbank-id>
            <moldb-smiles>NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1</moldb-smiles>
            <moldb-formula>C10H14N5O8P</moldb-formula>
            <moldb-inchi>InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1</moldb-inchi>
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            <foodb-id>FDB012390</foodb-id>
            <synonyms>5'-gmp;E 626;Gmp;Guanidine monophosphate;Guanosine 5'-monophosphate;Guanosine 5'-phosphate;Guanosine 5'-phosphorate;Guanosine 5'-phosphoric acid;Guanosine monophosphate;Guanosine-5'-monophosphate;Guanosine-5'-phosphate;Guanosine-phosphate;Guanylate;Guanylic acid;Pg;Guanosine 5'-monophosphoric acid;Guanosine monophosphoric acid;Guanosine-5'-monophosphoric acid</synonyms>
            <pwc-id>PW_C001080</pwc-id>
            <short-name>GSMP</short-name>
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            <name>Phosphate</name>
            <hmdb-id>HMDB0001429</hmdb-id>
            <description>Phosphate is a salt of phosphoric acid. In organic chemistry, a phosphate, or organophosphate, is an ester of phosphoric acid. Organic phosphates are important in biochemistry, biogeochemistry and ecology. Phosphate (Pi) is an essential component of life. In biological systems, phosphorus is found as a free phosphate ion in solution and is called inorganic phosphate, to distinguish it from phosphates bound in various phosphate esters. Inorganic phosphate is generally denoted Pi and at physiological (neutral) pH primarily consists of a mixture of HPO&lt;sup&gt;2-&lt;/sup&gt;&lt;sub&gt;4&lt;/sub&gt; and H&lt;sub&gt;2&lt;/sub&gt;PO&lt;sup&gt;-&lt;/sup&gt;&lt;sub&gt;4&lt;/sub&gt; ions. phosphates are most commonly found in the form of adenosine phosphates, (AMP, ADP and ATP) and in DNA and RNA and can be released by the hydrolysis of ATP or ADP. Similar reactions exist for the other nucleoside diphosphates and triphosphates. Phosphoanhydride bonds in ADP and ATP, or other nucleoside diphosphates and triphosphates, contain high amounts of energy which give them their vital role in all living organisms. Phosphate must be actively transported into cells against its electrochemical gradient. In vertebrates, two unrelated families of Na+-dependent Pi transporters carry out this task. Remarkably, the two families transport different Pi species: whereas type II Na+/Pi cotransporters (SCL34) prefer divalent HPO4(2), type III Na+/Pi cotransporters (SLC20) transport monovalent H2PO4. The SCL34 family comprises both electrogenic and electroneutral members that are expressed in various epithelia and other polarized cells. Through regulated activity in apical membranes of the gut and kidney, they maintain body Pi homeostasis, and in salivary and mammary glands, liver, and testes they play a role in modulating the Pi content of luminal fluids. Phosphate levels in the blood play an important role in hormone signaling and in bone homeostasis. In classical endocrine regulation, low serum phosphate induces the renal production of the seco-steroid hormone 1,25-dihydroxyvitamin D3 (1,25(OH)2D3).This active metabolite of vitamin D acts to restore circulating mineral (i.e. phosphate and calcium) levels by increasing absorption in the intestine, reabsorption in the kidney, and mobilization of calcium and phosphate from bone. Thus, chronic renal failure is associated with hyperparathyroidism, which in turn contributes to osteomalacia (softening of the bones). Another complication of chronic renal failure is hyperphosphatemia (low levels of phosphate in the blood). Hyperphosphatemia (excess levels of phosphate in the blood) is a prevalent condition in kidney dialysis patients and is associated with increased risk of mortality. Hypophosphatemia (hungry bone syndrome) has been associated to postoperative electrolyte aberrations and after parathyroidectomy. (PMID: 17581921, 11169009, 11039261, 9159312, 17625581)Fibroblast growth factor 23 (FGF-23) has recently been recognized as a key mediator of phosphate homeostasis, its most notable effect being promotion of phosphate excretion. FGF-23 was discovered to be involved in diseases such as autosomal dominant hypophosphatemic rickets, X-linked hypophosphatemia, and tumor-induced osteomalacia in which phosphate wasting was coupled to inappropriately low levels of 1,25(OH)2D3. FGF-23 is regulated by dietary phosphate in humans. In particular it was found that phosphate restriction decreased FGF-23, and phosphate loading increased FGF-23.</description>
            <cas>14265-44-2</cas>
            <kegg-id>C00009</kegg-id>
            <pubchem-cid>1061</pubchem-cid>
            <chebi-id>18367</chebi-id>
            <biocyc-id>CPD-8587</biocyc-id>
            <chemspider-id>1032</chemspider-id>
            <drugbank-id></drugbank-id>
            <moldb-smiles>OP(O)(O)=O</moldb-smiles>
            <moldb-formula>H3O4P</moldb-formula>
            <moldb-inchi>InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)</moldb-inchi>
            <moldb-inchikey>NBIIXXVUZAFLBC-UHFFFAOYSA-N</moldb-inchikey>
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            <drugbank-metabolite-id>DBMET00532</drugbank-metabolite-id>
            <foodb-id>FDB022617</foodb-id>
            <synonyms>Nfb orthophosphate;O-phosphoric acid;Ortho-phosphate;Orthophosphate (po43-);Orthophosphate(3-);Phosphate;Phosphate (po43-);Phosphate anion(3-);Phosphate ion (po43-);Phosphate ion(3-);Phosphate trianion;Phosphate(3-);Phosphoric acid ion(3-);Pi;[po4](3-);Orthophosphate;Phosphate ion;Po4(3-);Phosphoric acid;Orthophosphoric acid;Phosphoric acid ion</synonyms>
            <pwc-id>PW_C001104</pwc-id>
            <short-name>Pi</short-name>
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                <id type="integer">119982</id>
                <biological-state-id type="integer">406</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">120069</id>
                <biological-state-id type="integer">122</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">120699</id>
                <biological-state-id type="integer">407</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121057</id>
                <biological-state-id type="integer">124</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121216</id>
                <biological-state-id type="integer">125</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121268</id>
                <biological-state-id type="integer">429</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121352</id>
                <biological-state-id type="integer">121</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121409</id>
                <biological-state-id type="integer">123</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121423</id>
                <biological-state-id type="integer">382</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121852</id>
                <biological-state-id type="integer">405</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">123304</id>
                <biological-state-id type="integer">119</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">123621</id>
                <biological-state-id type="integer">118</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">123786</id>
                <biological-state-id type="integer">136</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">123838</id>
                <biological-state-id type="integer">464</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">123968</id>
                <biological-state-id type="integer">447</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">123981</id>
                <biological-state-id type="integer">399</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">124405</id>
                <biological-state-id type="integer">376</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">124948</id>
                <biological-state-id type="integer">472</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">125362</id>
                <biological-state-id type="integer">479</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">125446</id>
                <biological-state-id type="integer">297</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">125774</id>
                <biological-state-id type="integer">481</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">125954</id>
                <biological-state-id type="integer">299</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">126221</id>
                <biological-state-id type="integer">478</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">126594</id>
                <biological-state-id type="integer">300</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">126604</id>
                <biological-state-id type="integer">298</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">126723</id>
                <biological-state-id type="integer">484</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">126904</id>
                <biological-state-id type="integer">501</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">127413</id>
                <biological-state-id type="integer">388</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">127783</id>
                <biological-state-id type="integer">209</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">128166</id>
                <biological-state-id type="integer">395</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">128177</id>
                <biological-state-id type="integer">513</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">128315</id>
                <biological-state-id type="integer">389</biological-state-id>
              </element-state>
            </element-states>
          </compound>
          <compound>
            <id type="integer">1146</id>
            <name>Ribose 1-phosphate</name>
            <hmdb-id>HMDB0001489</hmdb-id>
            <description>Ribose 1-phosphate is an intermediate in the metabolism of Pyrimidine and the metabolism of Nicotinate and nicotinamide. It is a substrate for Uridine phosphorylase 2, Phosphoglucomutase, Purine nucleoside phosphorylase and Uridine phosphorylase 1. Ribose 1-phosphate can be formed from guanosine through the action of purine nucleoside phosphorylase. Ribose 1-phosphate can also act as a ribose donor in the synthesis of xanthosine as catalyzed by the same enzyme (purine nucleoside phosphorylase). The presence of guanase, which irreversibly converts guanine to xanthine, affects the overall process of guanosine transformation. As a result of this purine pathway, guanosine is converted into xanthosine, thus overcoming the lack of guanosine deaminase in mammals. The activated ribose moiety in Ribose 1-phosphate which stems from the catabolism of purine nucleosides can be transferred to uracil and, in the presence of ATP, used for the synthesis of pyrimidine nucleotides; therefore, purine nucleosides can act as ribose donors for the salvage of pyrimidine bases. (PMID: 9133638).</description>
            <cas>14075-00-4</cas>
            <kegg-id>C00620</kegg-id>
            <pubchem-cid>439236</pubchem-cid>
            <chebi-id>16300</chebi-id>
            <biocyc-id>RIBOSE-1P</biocyc-id>
            <chemspider-id>388373</chemspider-id>
            <drugbank-id>DB03101</drugbank-id>
            <moldb-smiles>OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H]1O</moldb-smiles>
            <moldb-formula>C5H11O8P</moldb-formula>
            <moldb-inchi>InChI=1S/C5H11O8P/c6-1-2-3(7)4(8)5(12-2)13-14(9,10)11/h2-8H,1H2,(H2,9,10,11)/t2-,3-,4-,5-/m1/s1</moldb-inchi>
            <moldb-inchikey>YXJDFQJKERBOBM-TXICZTDVSA-N</moldb-inchikey>
            <moldb-iupac nil="true"/>
            <moldb-average-mass>230.1098</moldb-average-mass>
            <moldb-mono-mass>230.01915384</moldb-mono-mass>
            <moldb-alogps-logs nil="true"/>
            <moldb-donor-count nil="true"/>
            <moldb-traditional-iupac nil="true"/>
            <moldb-formal-charge type="integer" nil="true"/>
            <moldb-physiological-charge type="integer" nil="true"/>
            <drugbank-metabolite-id nil="true"/>
            <foodb-id>FDB022650</foodb-id>
            <synonyms>1-o-phosphono-d-ribofuranose;D-ribofuranose 1-(dihydrogen phosphate);D-ribofuranose 1-phosphate;D-ribose-1-phosphate;D-ribose-1p;Ribofuranose 1-phosphate;Ribose 1-phosphate;A-d-ribofuranose 1-(dihydrogen phosphate);A-d-ribose 1-phosphate;Alpha-d-ribofuranose 1-(dihydrogen phosphate);Alpha-d-ribofuranose 1-phosphate;Alpha-d-ribose 1-phosphate;D-ribose 1-phosphate;D-ribose 1-phosphoric acid;Ribose 1-phosphoric acid</synonyms>
            <pwc-id>PW_C001146</pwc-id>
            <short-name>Rib-1P</short-name>
            <element-states>
              <element-state>
                <id type="integer">1770</id>
                <biological-state-id type="integer">2</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">1818</id>
                <biological-state-id type="integer">8</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">11783</id>
                <biological-state-id type="integer">198</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">77175</id>
                <biological-state-id type="integer">132</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">78676</id>
                <biological-state-id type="integer">111</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121864</id>
                <biological-state-id type="integer">122</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121968</id>
                <biological-state-id type="integer">124</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">124417</id>
                <biological-state-id type="integer">135</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">124521</id>
                <biological-state-id type="integer">118</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">126344</id>
                <biological-state-id type="integer">299</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">127725</id>
                <biological-state-id type="integer">388</biological-state-id>
              </element-state>
            </element-states>
          </compound>
          <compound>
            <id type="integer">86</id>
            <name>Guanine</name>
            <hmdb-id>HMDB0000132</hmdb-id>
            <description>Guanine is one of the five main nucleobases found in the nucleic acids DNA and RNA. Guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Being unsaturated, the bicyclic molecule is planar. The guanine nucleoside is called guanosine. The first isolation of guanine was reported in 1844 from the excreta of sea birds, known as guano, which was used as a source of fertilizer. High affinity binding of guanine nucleotides and the ability to hydrolyze bound GTP to GDP are characteristics of an extended family of intracellular proteins. Guanine nucleotide-binding regulatory proteins may be involved in the activation of phospholipases C and A2 by hormones and other ligands. The binding of hormones to receptors that activate phospholipase C is decreased by guanine nucleotides and these hormones also stimulate a high-affinity GTPase activity in cell membranes. Effects of hormones on phospholipase C activity in cell-free preparations are dependent on the presence of guanine nucleotides. Hypoxanthine-guanine phosphoribosyltransferase (HPRT, EC 2.4.2.8) is a purine salvage enzyme that catalyses the conversion of hypoxanthine and guanine to their respective mononucleotides. Partial deficiency of this enzyme can result in the overproduction of uric acid leading to a severe form of gout, whilst a virtual absence of HPRT activity causes the Lesch-Nyhan syndrome which is characterised by hyperuricaemia, mental retardation, choreoathetosis and compulsive self-mutilation. Peroxynitrite induces DNA base damage predominantly at guanine (G) and 8-oxoguanine (8-oxoG) nucleobases via oxidation reactions. G and 8-oxoG are the most reactive bases toward Peroxynitrite and possibly the major contributors to peroxynitrite-derived genotoxic and mutagenic lesions. The neutral G radical, reacts with NO2 to yield 8-nitroguanine and 5-nitro-4-guanidinohydantoin. (PMID: 16352449, 2435586, 2838362, 1487231).</description>
            <cas>73-40-5</cas>
            <kegg-id>C00242</kegg-id>
            <pubchem-cid>764</pubchem-cid>
            <chebi-id>16235</chebi-id>
            <biocyc-id>GUANINE</biocyc-id>
            <chemspider-id>744</chemspider-id>
            <drugbank-id>DB02377</drugbank-id>
            <moldb-smiles>NC1=NC(=O)C2=C(N1)N=CN2</moldb-smiles>
            <moldb-formula>C5H5N5O</moldb-formula>
            <moldb-inchi>InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)</moldb-inchi>
            <moldb-inchikey>UYTPUPDQBNUYGX-UHFFFAOYSA-N</moldb-inchikey>
            <moldb-iupac nil="true"/>
            <moldb-average-mass>151.1261</moldb-average-mass>
            <moldb-mono-mass>151.049409807</moldb-mono-mass>
            <moldb-alogps-logs nil="true"/>
            <moldb-donor-count nil="true"/>
            <moldb-traditional-iupac nil="true"/>
            <moldb-formal-charge type="integer" nil="true"/>
            <moldb-physiological-charge type="integer" nil="true"/>
            <drugbank-metabolite-id nil="true"/>
            <foodb-id>FDB004222</foodb-id>
            <synonyms>2-amino-1,7-dihydro-6h-purin-6-one;2-amino-1,9-dihydro-6h-purin-6-one;2-amino-1,9-dihydro-purin-6-one;2-amino-3,7-dihydro-6h-purin-6-one;2-amino-6-hydroxy-1h-purine;2-amino-6-hydroxypurine;2-amino-6-purinol;2-amino-hypoxanthine;2-aminohypoxanthine;6-hydroxy-2-aminopurine;C.i. natural white 1;Ci natural white 1;Dew pearl;Gua;Gun;Guanin;Guanine;Guanine enol;Mearlmaid;Mearlmaid aa;Natural white 1;Natural pearl essence;Naturon;Pathocidin;Pearl essence;Stella polaris;2-amino-6-oxopurine;G</synonyms>
            <pwc-id>PW_C000086</pwc-id>
            <short-name>Guanine</short-name>
            <element-states>
              <element-state>
                <id type="integer">1814</id>
                <biological-state-id type="integer">8</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">11779</id>
                <biological-state-id type="integer">198</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">78674</id>
                <biological-state-id type="integer">111</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121861</id>
                <biological-state-id type="integer">122</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">124414</id>
                <biological-state-id type="integer">135</biological-state-id>
              </element-state>
            </element-states>
          </compound>
          <compound>
            <id type="integer">190</id>
            <name>Phosphoribosyl pyrophosphate</name>
            <hmdb-id>HMDB0000280</hmdb-id>
            <description>Phosphoribosyl pyrophosphate (PRPP) is a pentosephosphate. The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides. It is formed from ribose 5-phosphate by the enzyme ribose-phosphate diphosphokinase. It plays a role in transferring phosphate groups in several reactions. (Wikipedia).</description>
            <cas>7540-64-9</cas>
            <kegg-id>C00119</kegg-id>
            <pubchem-cid>7339</pubchem-cid>
            <chebi-id>17111</chebi-id>
            <biocyc-id>PRPP</biocyc-id>
            <chemspider-id>7062</chemspider-id>
            <drugbank-id>DB01632</drugbank-id>
            <moldb-smiles>O[C@H]1[C@@H](O)[C@@H](OP(O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O</moldb-smiles>
            <moldb-formula>C5H13O14P3</moldb-formula>
            <moldb-inchi>InChI=1S/C5H13O14P3/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13)/t2-,3-,4-,5-/m1/s1</moldb-inchi>
            <moldb-inchikey>PQGCEDQWHSBAJP-TXICZTDVSA-N</moldb-inchikey>
            <moldb-iupac nil="true"/>
            <moldb-average-mass>390.0696</moldb-average-mass>
            <moldb-mono-mass>389.95181466</moldb-mono-mass>
            <moldb-alogps-logs nil="true"/>
            <moldb-donor-count nil="true"/>
            <moldb-traditional-iupac nil="true"/>
            <moldb-formal-charge type="integer" nil="true"/>
            <moldb-physiological-charge type="integer" nil="true"/>
            <drugbank-metabolite-id nil="true"/>
            <foodb-id>FDB021928</foodb-id>
            <synonyms>5-phospho-a-d-ribose-1-diphosphate;5-phospho-a-d-ribosyl pyrophosphate;5-phospho-alpha-d-ribose 1-diphosphate;5-phospho-alpha-d-ribose-1-diphosphate;5-phospho-alpha-d-ribosyl pyrophosphate;5-phospho-alpha-d-riobse 1-diphosphate;5-phospho-alpha-delta-ribose 1-diphosphate;5-phospho-alpha-delta-ribose-1-diphosphate;5-phospho-alpha-delta-ribosyl pyrophosphate;5-phosphoribose 1-pyrophosphate;5-phosphoribosyl 1-diphosphate;5-phosphoribosyl a-1-pyrophosphate;5-phosphoribosyl-1-pyrophosphate;5-phosphorylribose 1-a-diphosphate;5-phosphorylribose 1-alpha-diphosphate;5-phosphorylribose 1-pyrophosphate;5-phosphorylribosyl 1-pyrophosphate;Pp-ribose-p;Prpp;Prib-pp;Phosphoribosyl pyrophosphate;Phosphoribosyl-1-pyrophosphate;Phosphoribosyl-pyrophosphate;Phosphoribosylpyrophosphorate;Phosphoribosylpyrophosphoric acid;A-d-5-(dihydrogen phosphate) 1-(trihydrogen pyrophosphate) ribofuranose;A-d-5-phosphoribosyl 1-pyrophosphate;A-d-ribofuranose 5-phosphate 1-pyrophosphate;A-d-ribofuranose, 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate);Alpha-d-5-(dihydrogen phosphate) 1-(trihydrogen pyrophosphate) ribofuranose;Alpha-d-5-phosphoribosyl 1-pyrophosphate;Alpha-d-ribofuranose 5-phosphate 1-pyrophosphate;Alpha-d-ribofuranose, 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate);Alpha-delta-5-(dihydrogen phosphate) 1-(trihydrogen pyrophosphate) ribofuranose;Alpha-delta-5-phosphoribosyl 1-pyrophosphate;Alpha-delta-ribofuranose 5-phosphate 1-pyrophosphate;5-phosphoribosyl 1-pyrophosphate;5-phosphoribosyl diphosphate;Alpha-d-ribofuranose 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate);Alpha-phosphoribosylpyrophosphoric acid;Phosphoribosylpyrophosphate;5-phospho-a-d-ribose 1-diphosphate;5-phospho-a-d-ribose 1-diphosphoric acid;5-phospho-alpha-d-ribose 1-diphosphoric acid;5-phospho-α-d-ribose 1-diphosphate;5-phospho-α-d-ribose 1-diphosphoric acid;Phosphoribosyl pyrophosphoric acid;5-phosphoribosyl 1-pyrophosphoric acid;5-phosphoribosyl diphosphoric acid;A-d-ribofuranose 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate);A-d-ribofuranose 5-(dihydrogen phosphoric acid) 1-(trihydrogen diphosphoric acid);Alpha-d-ribofuranose 5-(dihydrogen phosphoric acid) 1-(trihydrogen diphosphoric acid);α-d-ribofuranose 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate);α-d-ribofuranose 5-(dihydrogen phosphoric acid) 1-(trihydrogen diphosphoric acid);A-phosphoribosylpyrophosphate;A-phosphoribosylpyrophosphoric acid;Alpha-phosphoribosylpyrophosphate;α-phosphoribosylpyrophosphate;α-phosphoribosylpyrophosphoric acid</synonyms>
            <pwc-id>PW_C000190</pwc-id>
            <short-name>PRPP</short-name>
            <element-states>
              <element-state>
                <id type="integer">1774</id>
                <biological-state-id type="integer">2</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">1815</id>
                <biological-state-id type="integer">8</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">5816</id>
                <biological-state-id type="integer">108</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">11780</id>
                <biological-state-id type="integer">198</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">42663</id>
                <biological-state-id type="integer">315</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">77176</id>
                <biological-state-id type="integer">132</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">78002</id>
                <biological-state-id type="integer">111</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">80680</id>
                <biological-state-id type="integer">135</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">111657</id>
                <biological-state-id type="integer">7</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">120160</id>
                <biological-state-id type="integer">122</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">121950</id>
                <biological-state-id type="integer">124</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">124503</id>
                <biological-state-id type="integer">118</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">125521</id>
                <biological-state-id type="integer">297</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">126346</id>
                <biological-state-id type="integer">299</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">127056</id>
                <biological-state-id type="integer">205</biological-state-id>
              </element-state>
              <element-state>
                <id type="integer">127709</id>
                <biological-state-id type="integer">388</biological-state-id>
              </element-state>
            </element-states>
          </compound>
          <compound>
            <id type="integer">170</id>
            <name>Pyrophosphate</name>
            <hmdb-id>HMDB0000250</hmdb-id>
            <description>The anion, the salts, and the esters of pyrophosphoric acid are called pyrophosphates. The pyrophosphate anion is abbreviated PPi and is formed by the hydrolysis of ATP into AMP in cells. This hydrolysis is called pyrophosphorolysis. The pyrophosphate anion has the structure P2O74-, and is an acid anhydride of phosphate. It is unstable in aqueous solution and rapidly hydrolyzes into inorganic phosphate. Pyrophosphate is an osteotoxin (arrests bone development) and an arthritogen (promotes arthritis). It is also a metabotoxin (an endogenously produced metabolite that causes adverse health affects at chronically high levels). Chronically high levels of pyrophosphate are associated with hypophosphatasia. Hypophosphatasia (also called deficiency of alkaline phosphatase or phosphoethanolaminuria) is a rare, and sometimes fatal, metabolic bone disease. Hypophosphatasia is associated with a molecular defect in the gene encoding tissue non-specific alkaline phosphatase (TNSALP). TNSALP is an enzyme that is tethered to the outer surface of osteoblasts and chondrocytes. TNSALP hydrolyzes several substances, including inorganic pyrophosphate (PPi) and pyridoxal 5'-phosphate (PLP), a major form of vitamin B6. When TSNALP is low, inorganic pyrophosphate (PPi) accumulates outside of cells and inhibits the formation of hydroxyapatite, one of the main components of bone, causing rickets in infants and children and osteomalacia (soft bones) in adults. Vitamin B6 must be dephosphorylated by TNSALP before it can cross the cell membrane. Vitamin B6 deficiency in the brain impairs synthesis of neurotransmitters which can cause seizures. In some cases, a build-up of calcium pyrophosphate dihydrate crystals in the joints can cause pseudogout.</description>
            <cas>14000-31-8</cas>
            <kegg-id>C00013</kegg-id>
            <pubchem-cid>644102</pubchem-cid>
            <chebi-id>18361</chebi-id>
            <biocyc-id>PPI</biocyc-id>
            <chemspider-id>559142</chemspider-id>
            <drugbank-id>DB04160</drugbank-id>
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            <foodb-id>FDB021918</foodb-id>
            <synonyms>(4-)diphosphoric acid ion;(p2o74-)diphosphate;Diphosphate;Diphosphoric acid;Ppi;Pyrometaphosphate;Pyrophosphate;Pyrophosphate tetraanion;Pyrophosphate(4-) ion;[o3popo3](4-);Diphosphat;P2o7(4-);Pyrophosphat;Pyrophosphate ion;Phosphonato phosphoric acid;Pyrophosphoric acid;Pyrophosphoric acid ion</synonyms>
            <pwc-id>PW_C000170</pwc-id>
            <short-name>Ppi</short-name>
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            <uniprot-id>P0A9M5</uniprot-id>
            <description>Involved in nucleoside metabolic process. Acts on guanine, xanthine and to a lesser extent hypoxanthine.</description>
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            <genbank-id>AP009048</genbank-id>
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            <ec-numbers>2.4.2.22</ec-numbers>
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                <currency type="boolean">false</currency>
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            <font-size>regular</font-size>
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            <font-size>regular</font-size>
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            <visualization-template-id type="integer">235</visualization-template-id>
            <label-text>Outer Membrane</label-text>
            <x type="integer">1092</x>
            <y type="integer">50</y>
            <zindex type="integer">20</zindex>
            <scale-x type="decimal">1.7</scale-x>
            <scale-y type="decimal">1.7</scale-y>
            <width>200</width>
            <height>15</height>
          </label-location>
          <label-location>
            <id type="integer">2840477</id>
            <visualization-template-id type="integer">235</visualization-template-id>
            <label-text>Bacterial Chromosome</label-text>
            <x type="integer">2320</x>
            <y type="integer">1455</y>
            <zindex type="integer">20</zindex>
            <scale-x type="decimal">1.6</scale-x>
            <scale-y type="decimal">1.6</scale-y>
            <width>200</width>
            <height>15</height>
          </label-location>
          <label-location>
            <id type="integer">4107342</id>
            <visualization-template-id type="integer">235</visualization-template-id>
            <label-text>Peptidoglycan</label-text>
            <x type="integer">1510</x>
            <y type="integer">185</y>
            <zindex type="integer">20</zindex>
            <scale-x type="decimal">1.6</scale-x>
            <scale-y type="decimal">1.6</scale-y>
            <width>200</width>
            <height>15</height>
          </label-location>
        </label-locations>
        <zoom-visualizations>
          <zoom-visualization>
            <id type="integer">494098</id>
            <p1x type="integer">269</p1x>
            <p1y type="integer">1152</p1y>
            <p2x type="integer">600</p2x>
            <p2y type="integer">95</p2y>
            <p3x type="integer">3150</p3x>
            <p3y type="integer">2206</p3y>
            <visualization-template-id type="integer">39</visualization-template-id>
            <color nil="true"/>
            <zindex type="integer">4</zindex>
            <label></label>
            <width>2550</width>
            <height>2111</height>
          </zoom-visualization>
        </zoom-visualizations>
      </pathway-visualization>
    </pathway-visualization-context>
  </pathway-visualization-contexts>
</super-pathway-visualization>
