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Pathway Description
Operon: High Frequency of Lysogenization
Escherichia coli
Protein Pathway
The high frequency of lyzogenization operon is a polycistronic operon consisting of the genes: hfq, hflX, hflK and hflC. This operon is regulated by CRP-cAMP DNA-binding transcriptional dual regulator being binded to a crp binding site in the -96.5 bp from the promoter
References
Operon: High Frequency of Lysogenization References
Huerta AM, Collado-Vides J: Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals. J Mol Biol. 2003 Oct 17;333(2):261-78.
Pubmed: 14529615
Lin HH, Hsu CC, Yang CD, Ju YW, Chen YP, Tseng CP: Negative effect of glucose on ompA mRNA stability: a potential role of cyclic AMP in the repression of hfq in Escherichia coli. J Bacteriol. 2011 Oct;193(20):5833-40. doi: 10.1128/JB.05359-11. Epub 2011 Aug 12.
Pubmed: 21840983
Nonaka G, Blankschien M, Herman C, Gross CA, Rhodius VA: Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress. Genes Dev. 2006 Jul 1;20(13):1776-89. doi: 10.1101/gad.1428206.
Pubmed: 16818608
Tsui HC, Feng G, Winkler ME: Transcription of the mutL repair, miaA tRNA modification, hfq pleiotropic regulator, and hflA region protease genes of Escherichia coli K-12 from clustered Esigma32-specific promoters during heat shock. J Bacteriol. 1996 Oct;178(19):5719-31.
Pubmed: 8824618
Zaslaver A, Bren A, Ronen M, Itzkovitz S, Kikoin I, Shavit S, Liebermeister W, Surette MG, Alon U: A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Nat Methods. 2006 Aug;3(8):623-8. doi: 10.1038/nmeth895.
Pubmed: 16862137
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