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Pathway Description
Operon: Pyrimidine Biosynthesis
Escherichia coli
Signaling Pathway
The pyrimidine biosynthesis operon consists of the genes pyrB and pyrI. This is a bicistronic operon. The operon transcription is negatively regulated by the intracellullar levels of UTP. The higher the UTP levels, the less expressiong of the operon
References
Operon: Pyrimidine Biosynthesis References
Turnbough CL Jr, Hicks KL, Donahue JP: Attenuation control of pyrBI operon expression in Escherichia coli K-12. Proc Natl Acad Sci U S A. 1983 Jan;80(2):368-72.
Pubmed: 6300835
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