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Pathway Description
Operon: DNA Replication (dnaTC)
Escherichia coli
Protein Pathway
The DNA replication (dnaTC) operon is a bicistronic operon consisting of dnaC and dnaT. This operon is regulated by a rho-independent terminator. The product of dnaC and dnaT are respectively primosomal protein 1 and DNA replication protein DnaC. DnaT is also responsible for inducting replication of stable DNA during SOS response.
References
Operon: DNA Replication (dnaTC) References
Masai H, Bond MW, Arai K: Cloning of the Escherichia coli gene for primosomal protein i: the relationship to dnaT, essential for chromosomal DNA replication. Proc Natl Acad Sci U S A. 1986 Mar;83(5):1256-60.
Pubmed: 3006041
Masai H, Arai K: Operon structure of dnaT and dnaC genes essential for normal and stable DNA replication of Escherichia coli chromosome. J Biol Chem. 1988 Oct 15;263(29):15083-93.
Pubmed: 2844800
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