D-Fructose 2,6-bisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001047
xref: Reference/CAS 79082-92-1
xref: Reference/BioCyc CPD-535
xref: Reference/ChEBI CHEBI 28602
xref: Reference/ChemSpider 94762
xref: Reference/KEGG Compound C00665
xref: Reference/PubChem-compound 105021
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C000825

Reference/BioCyc SUCROSE
type: UnificationXref
id: SUCROSE
db: BioCyc

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/BioCyc CPD-535
type: UnificationXref
id: CPD-535
db: BioCyc

Glucose-6-phosphate isomerase
type: ProteinReference
xref: Reference/UniProt P12709

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/KEGG Compound C00794
type: UnificationXref
id: C00794
db: KEGG Compound

NADH
type: SmallMolecule
entity reference: NADH

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Sucrose
type: SmallMolecule
entity reference: Sucrose

Reference/ChEBI CHEBI 48095
type: UnificationXref
id: CHEBI:48095
db: ChEBI

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Hexokinase 2
type: ProteinReference
xref: Reference/UniProt P04807

keto-D-fructose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 48095
xref: Reference/PubChem-compound 5984
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C044535

Hexokinase I
type: ProteinReference
xref: Reference/UniProt P04806

sucrose-6-phosphate
type: SmallMolecule
entity reference: sucrose-6-phosphate

6-phosphofructo-2-kinase subunit II
type: ProteinReference
xref: Reference/UniProt Q12471

6-phosphofructose-2-kinase subunit I
type: ProteinReference
xref: Reference/UniProt P40433

Compound/PW C001906/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose 6-phosphate
stoichiometric coefficient: 1.0

Sorbitol Dehydrogenase
type: ProteinReference
xref: Reference/UniProt P35497

NAD
type: SmallMolecule
entity reference: NAD

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Sorbitol
type: SmallMolecule
entity reference: Sorbitol

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

SubPathwayInteraction111233
type: Interaction
name: SubPathway111233Reaction
name: SubPathwayReaction

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Compound/PW C000177/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sucrose
stoichiometric coefficient: 1.0

Sorbitol
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5780
xref: Reference/HMDB HMDB0000247
xref: Reference/ChEBI CHEBI 17924
xref: Reference/ChemSpider 5576
xref: Reference/CAS 50-70-4
xref: Reference/KEGG Compound C00794
chemical formula: C6H14O6
molecular weight: 182.07904
structure: ChemicalStructure/PW C000168

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/ChEBI CHEBI 42560
type: UnificationXref
id: CHEBI:42560
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Invertase
type: ProteinReference
xref: Reference/UniProt P00724

fructose-2,6-bisphosphatase
type: ProteinReference
xref: Reference/UniProt P32604

Reference/HMDB HMDB0003498
type: UnificationXref
id: HMDB0003498
db: HMDB

sucrose-6-phosphate
type: SmallMoleculeReference
chemical formula: C12H23O14P
molecular weight: 422.08255
structure: ChemicalStructure/PW C041038

Reference/ChemSpider 5743
type: UnificationXref
id: 5743
db: ChemSpider

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/KEGG Compound C05345
type: UnificationXref
id: C05345
db: KEGG Compound

Compound/PW C000825/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Fructose 2,6-bisphosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001401
type: UnificationXref
id: HMDB0001401
db: HMDB

Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
type: UnificationXref
id: ALPHA-GLUCOSE-16-BISPHOSPHATE
db: BioCyc

ChemicalStructure/PW C001083
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

β-D-Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 388538
xref: Reference/KEGG Compound C01172
xref: Reference/ChEBI CHEBI 17719
xref: Reference/HMDB HMDB0003498
xref: Reference/PubChem-compound 439427
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001906

D-Fructose 2,6-bisphosphate
type: SmallMolecule
entity reference: D-Fructose 2,6-bisphosphate

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reference/PubChem-compound 5988
type: UnificationXref
id: 5988
db: PubChem-compound

Reference/PubChem-compound 5984
type: UnificationXref
id: 5984
db: PubChem-compound

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Saccharomyces cerevisiae
type: BioSource
xref: Reference/TAXONOMY 4932

ChemicalStructure/PW C041111
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChemSpider 5768
type: UnificationXref
id: 5768
db: ChemSpider

Reference/ChemSpider 389526
type: UnificationXref
id: 389526
db: ChemSpider

Reference/CAS 50-70-4
type: UnificationXref
id: 50-70-4
db: CAS

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/ChEBI CHEBI 28602
type: UnificationXref
id: CHEBI:28602
db: ChEBI

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/ChemSpider 94762
type: UnificationXref
id: 94762
db: ChemSpider

6-phosphofructose-2-kinase
type: Complex
component: 6-phosphofructose-2-kinase subunit I
component: 6-phosphofructo-2-kinase subunit II

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/CAS 79082-92-1
type: UnificationXref
id: 79082-92-1
db: CAS

ChemicalStructure/PW C001906
type: ChemicalStructure
structure format: SMILES

β-D-fructofuranose 6-phosphate
type: SmallMolecule
entity reference: β-D-fructofuranose 6-phosphate

β-D-fructofuranose
type: SmallMolecule
entity reference: β-D-fructofuranose

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

α-D-Glucose
type: SmallMolecule
entity reference: α-D-Glucose

Reference/PathWhiz PW002390
type: UnificationXref
id: PW002390
db: PathWhiz

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

β-D-Fructose 6-phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440641
xref: Reference/ChemSpider 389526
xref: Reference/ChEBI CHEBI 16084
xref: Reference/KEGG Compound C05345
xref: Reference/BioCyc FRUCTOSE-6P
xref: Reference/HMDB HMDB0003971
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C002021

Reference/UniProt P04806
type: UnificationXref
id: P04806
db: UniProt

Reference/UniProt P04807
type: UnificationXref
id: P04807
db: UniProt

Compound/PW C040941/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-fructofuranose 6-phosphate
stoichiometric coefficient: 1.0

Fructokinase
type: Complex
component: Hexokinase 2
component: Hexokinase I

β-D-Fructose 6-phosphate
type: SmallMolecule
entity reference: β-D-Fructose 6-phosphate

α-D-Glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003345
xref: Reference/ChemSpider 71358
xref: Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
xref: Reference/PubChem-compound 79025
xref: Reference/ChEBI CHEBI 17925
xref: Reference/CAS 492-62-6
xref: Reference/KEGG Compound C00267
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C001851

Reference/HMDB HMDB0003971
type: UnificationXref
id: HMDB0003971
db: HMDB

β-D-fructofuranose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 42560
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C041111

keto-D-fructose
type: SmallMolecule
entity reference: keto-D-fructose

Reference/ChemSpider 388538
type: UnificationXref
id: 388538
db: ChemSpider

Reference/ChEBI CHEBI 17924
type: UnificationXref
id: CHEBI:17924
db: ChEBI

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

β-D-fructofuranose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 57634
chemical formula: C6H11O9P
molecular weight: 258.01517
structure: ChemicalStructure/PW C040941

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Protein/10560/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glucose-6-phosphate isomerase
stoichiometric coefficient: 2.0

Reference/BioCyc FRUCTOSE-6P
type: UnificationXref
id: FRUCTOSE-6P
db: BioCyc

Reference/UniProt P32604
type: UnificationXref
id: P32604
db: UniProt

Reference/PubChem-compound 105021
type: UnificationXref
id: 105021
db: PubChem-compound

Reference/PubChem-compound 440641
type: UnificationXref
id: 440641
db: PubChem-compound

Fructose Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/24977
pathway order: PathwaySubPathway/111233
pathway order: PathwayEnzymeReaction/24978
pathway order: PathwayEnzymeReaction/24979
pathway order: PathwayEnzymeReaction/24980
pathway order: PathwayEnzymeReaction/24981
pathway order: PathwayEnzymeReaction/24982
pathway order: PathwayEnzymeReaction/24983
pathway order: PathwayEnzymeReaction/24984
pathway order: PathwayEnzymeReaction/24985
pathway component: ReactionCatalysis6264
pathway component: ReactionCatalysis6263
pathway component: ReactionCatalysis6262
pathway component: ReactionCatalysis6261
pathway component: 3.1.3.46
pathway component: Endocytosis
pathway component: 3.2.1.26
pathway component: Reaction6339
pathway component: Reaction6340
pathway component: ReactionCatalysis6268
pathway component: ReactionCatalysis6267
pathway component: 5.3.1.9
pathway component: ReactionCatalysis6266
pathway component: ReactionCatalysis6265
pathway component: 1.1.1.14
pathway component: Reaction6334
pathway component: 2.7.1.1
pathway component: 2.7.1.105
xref: Reference/SMPDB SMP0002314
xref: Reference/PathWhiz PW002390
organism: Saccharomyces cerevisiae

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/PubChem-compound 5958
type: UnificationXref
id: 5958
db: PubChem-compound

Compound/PW C041111/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-fructofuranose
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/UniProt P40433
type: UnificationXref
id: P40433
db: UniProt

Sucrose
type: SmallMoleculeReference
xref: Reference/BioCyc SUCROSE
xref: Reference/CAS 57-50-1
xref: Reference/HMDB HMDB0000258
xref: Reference/ChemSpider 5768
xref: Reference/KEGG Compound C00089
xref: Reference/PubChem-compound 5988
xref: Reference/ChEBI CHEBI 17992
chemical formula: C12H22O11
molecular weight: 342.1162
structure: ChemicalStructure/PW C000177

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Compound/PW C041038/Stoichiometry/1.0
type: Stoichiometry
physical entity: sucrose-6-phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00267
type: UnificationXref
id: C00267
db: KEGG Compound

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/HMDB HMDB0000247
type: UnificationXref
id: HMDB0000247
db: HMDB

Putative glucokinase-2
type: ProteinReference
xref: Reference/UniProt Q04409

Reference/ChEBI CHEBI 17925
type: UnificationXref
id: CHEBI:17925
db: ChEBI

ChemicalStructure/PW C041038
type: ChemicalStructure
structure format: SMILES

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Water
type: SmallMolecule
entity reference: Water

Reference/HMDB HMDB0000258
type: UnificationXref
id: HMDB0000258
db: HMDB

ChemicalStructure/PW C000177
type: ChemicalStructure
structure format: SMILES

Compound/PW C044535/Stoichiometry/1.0
type: Stoichiometry
physical entity: keto-D-fructose
stoichiometric coefficient: 1.0

Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00092
xref: Reference/BioCyc GLC-6-P
xref: Reference/HMDB HMDB0001401
xref: Reference/PubChem-compound 5958
xref: Reference/ChemSpider 5743
xref: Reference/CAS 56-73-5
xref: Reference/ChEBI CHEBI 4170
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001083

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Compound/PW C002021/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Fructose 6-phosphate
stoichiometric coefficient: 1.0

Reference/UniProt Q12471
type: UnificationXref
id: Q12471
db: UniProt

Reference/ChEBI CHEBI 17992
type: UnificationXref
id: CHEBI:17992
db: ChEBI

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/SMPDB SMP0002314
type: UnificationXref
id: SMP0002314
db: SMPDB

Reference/PubChem-compound 439427
type: UnificationXref
id: 439427
db: PubChem-compound

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

ChemicalStructure/PW C000825
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 4170
type: UnificationXref
id: CHEBI:4170
db: ChEBI

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/ChEBI CHEBI 17719
type: UnificationXref
id: CHEBI:17719
db: ChEBI

Glucose 6-phosphate
type: SmallMolecule
entity reference: Glucose 6-phosphate

Reference/CAS 492-62-6
type: UnificationXref
id: 492-62-6
db: CAS

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/ChEBI CHEBI 16084
type: UnificationXref
id: CHEBI:16084
db: ChEBI

Reference/ChemSpider 5576
type: UnificationXref
id: 5576
db: ChemSpider

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Glucose-6-phosphate isomerase
type: Complex
component stoichiometry: Protein/10560/Stoichiometry/2.0
component: Glucose-6-phosphate isomerase

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/BioCyc GLC-6-P
type: UnificationXref
id: GLC-6-P
db: BioCyc

Endocytosis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway111233
pathway component: SubPathwayInteraction111233
name: SubPathway

ChemicalStructure/PW C000168
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Invertase
type: Protein
entity reference: Invertase

ChemicalStructure/PW C040941
type: ChemicalStructure
structure format: SMILES
structure data: OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

β-D-Glucose 6-phosphate
type: SmallMolecule
entity reference: β-D-Glucose 6-phosphate

Hexokinase 2
type: Protein
entity reference: Hexokinase 2

6-phosphofructose-2-kinase subunit I
type: Protein
entity reference: 6-phosphofructose-2-kinase subunit I

6-phosphofructo-2-kinase subunit II
type: Protein
entity reference: 6-phosphofructo-2-kinase subunit II

fructose-2,6-bisphosphatase
type: Protein
entity reference: fructose-2,6-bisphosphatase

Phosphate
type: SmallMolecule
entity reference: Phosphate

Sorbitol Dehydrogenase
type: Protein
entity reference: Sorbitol Dehydrogenase

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Hexokinase I
type: Protein
entity reference: Hexokinase I

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/KEGG Compound C01172
type: UnificationXref
id: C01172
db: KEGG Compound

Reaction6340
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001083/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: Glucose 6-phosphate
spontaneous: false
left: α-D-Glucose
left: Adenosine triphosphate
name: Adenosine triphosphate + α-D-Glucose → Adenosine diphosphate + Glucose 6-phosphate + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

5.3.1.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001083/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040941/Stoichiometry/1.0
right: β-D-fructofuranose 6-phosphate
spontaneous: false
EC number: 5.3.1.9
left: Glucose 6-phosphate
name: Glucose 6-phosphate → β-D-fructofuranose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P35497
type: UnificationXref
id: P35497
db: UniProt

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

ReactionCatalysis6264
type: Catalysis
controller: fructose-2,6-bisphosphatase
controlled: 3.1.3.46
control type: ACTIVATION

ReactionCatalysis6263
type: Catalysis
controller: 6-phosphofructose-2-kinase
controlled: 2.7.1.105
control type: ACTIVATION

ReactionCatalysis6262
type: Catalysis
controller: Fructokinase
controlled: 2.7.1.1
control type: ACTIVATION

ReactionCatalysis6261
type: Catalysis
controller: Sorbitol Dehydrogenase
controlled: 1.1.1.14
control type: ACTIVATION

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/KEGG Compound C00089
type: UnificationXref
id: C00089
db: KEGG Compound

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/UniProt P12709
type: UnificationXref
id: P12709
db: UniProt

Glucose-6-phosphate isomerase
type: Protein
entity reference: Glucose-6-phosphate isomerase

3.1.3.46
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040941/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000825/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: β-D-fructofuranose 6-phosphate
right: Phosphate
spontaneous: false
EC number: 3.1.3.46
left: Water
left: D-Fructose 2,6-bisphosphate
name: D-Fructose 2,6-bisphosphate + Water → Phosphate + β-D-fructofuranose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00092
type: UnificationXref
id: C00092
db: KEGG Compound

3.2.1.26
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001906/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041111/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041038/Stoichiometry/1.0
right: β-D-fructofuranose
right: β-D-Glucose 6-phosphate
spontaneous: false
EC number: 3.2.1.26
left: sucrose-6-phosphate
left: Water
name: Water + sucrose-6-phosphate → β-D-Glucose 6-phosphate + β-D-fructofuranose
conversion direction: LEFT_TO_RIGHT

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reaction6339
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000177/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041111/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001851/Stoichiometry/1.0
right: β-D-fructofuranose
right: α-D-Glucose
spontaneous: false
left: Water
left: Sucrose
name: Sucrose + Water → α-D-Glucose + β-D-fructofuranose
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 71358
type: UnificationXref
id: 71358
db: ChemSpider

ReactionCatalysis6268
type: Catalysis
controller: Glucose-6-phosphate isomerase
controlled: 5.3.1.9
control type: ACTIVATION

Reference/PubChem-compound 79025
type: UnificationXref
id: 79025
db: PubChem-compound

ReactionCatalysis6267
type: Catalysis
controller: Putative glucokinase-2
controlled: Reaction6340
control type: ACTIVATION

ReactionCatalysis6266
type: Catalysis
controller: Invertase
controlled: Reaction6339
control type: ACTIVATION

ReactionCatalysis6265
type: Catalysis
controller: Invertase
controlled: 3.2.1.26
control type: ACTIVATION

1.1.1.14
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000168/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C044535/Stoichiometry/1.0
right: NADH
right: keto-D-fructose
right: Hydrogen Ion
spontaneous: false
EC number: 1.1.1.14
left: NAD
left: Sorbitol
name: NAD + Sorbitol → Hydrogen Ion + NADH + keto-D-fructose
conversion direction: LEFT_TO_RIGHT

Reaction6334
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041111/Stoichiometry/1.0
participant stoichiometry: Compound/PW C044535/Stoichiometry/1.0
right: β-D-fructofuranose
spontaneous: true
left: keto-D-fructose
name: keto-D-fructose → β-D-fructofuranose
conversion direction: LEFT_TO_RIGHT

2.7.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002021/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041111/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: β-D-Fructose 6-phosphate
right: Hydrogen Ion
right: Adenosine triphosphate
spontaneous: false
EC number: 2.7.1.1
left: β-D-fructofuranose
left: Adenosine triphosphate
name: Adenosine triphosphate + β-D-fructofuranose → Adenosine triphosphate + Hydrogen Ion + β-D-Fructose 6-phosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.105
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040941/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000825/Stoichiometry/1.0
right: Adenosine diphosphate
right: D-Fructose 2,6-bisphosphate
right: Hydrogen Ion
spontaneous: false
EC number: 2.7.1.105
left: β-D-fructofuranose 6-phosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + β-D-fructofuranose 6-phosphate → Adenosine diphosphate + D-Fructose 2,6-bisphosphate + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P00724
type: UnificationXref
id: P00724
db: UniProt

Reference/TAXONOMY 4932
type: UnificationXref
id: 4932
db: TAXONOMY

Compound/PW C001851/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 1.0

Putative glucokinase-2
type: Protein
entity reference: Putative glucokinase-2

Reference/CAS 56-73-5
type: UnificationXref
id: 56-73-5
db: CAS

Reference/HMDB HMDB0001047
type: UnificationXref
id: HMDB0001047
db: HMDB

Reference/HMDB HMDB0003345
type: UnificationXref
id: HMDB0003345
db: HMDB

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Compound/PW C000168/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sorbitol
stoichiometric coefficient: 1.0

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Compound/PW C001083/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5780
type: UnificationXref
id: 5780
db: PubChem-compound

Reference/CAS 57-50-1
type: UnificationXref
id: 57-50-1
db: CAS

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

ChemicalStructure/PW C044535
type: ChemicalStructure
structure format: SMILES
structure data: OCC(O)C(O)C(O)C(=O)CO

Reference/UniProt Q04409
type: UnificationXref
id: Q04409
db: UniProt

Reference/KEGG Compound C00665
type: UnificationXref
id: C00665
db: KEGG Compound

Reference/ChEBI CHEBI 57634
type: UnificationXref
id: CHEBI:57634
db: ChEBI

ChemicalStructure/PW C002021
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001851
type: ChemicalStructure
structure format: SMILES