Glycerol-3-phosphate O-acyltransferase 2
type: Protein
entity reference: Glycerol-3-phosphate O-acyltransferase 2

Glycerol-3-phosphate O-acyltransferase 1
type: Protein
entity reference: Glycerol-3-phosphate O-acyltransferase 1

Compound/PW C000497/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dodecanoic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

Reference/UniProt Q06508
type: UnificationXref
id: Q06508
db: UniProt

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/CAS 56-81-5
type: UnificationXref
id: 56-81-5
db: CAS

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Lauroyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc LAUROYLCOA-CPD
xref: Reference/KEGG Compound C01832
xref: Reference/ChEBI CHEBI 15521
xref: Reference/HMDB HMDB0003571
xref: Reference/CAS 6244-92-4
xref: Reference/ChemSpider 145018
xref: Reference/PubChem-compound 165436
chemical formula: C33H58N7O17P3S
molecular weight: 949.2823
structure: ChemicalStructure/PW C001928

Reference/PubChem-compound 6132
type: UnificationXref
id: 6132
db: PubChem-compound

Reference/ChEBI CHEBI 17239
type: UnificationXref
id: CHEBI:17239
db: ChEBI

Palmitoleic acid
type: SmallMolecule
entity reference: Palmitoleic acid

3.1.1.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C057245/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043361/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001811/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Hydrogen Ion
right: Palmitoleic acid
right: DG(12:0/16:0/0:0)
spontaneous: false
EC number: 3.1.1.13
left: Water
left: TG(12:0/16:0/16:1(9Z))
name: TG(12:0/16:0/16:1(9Z)) + Water → DG(12:0/16:0/0:0) + Hydrogen Ion + Palmitoleic acid
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

2.3.1.20
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002798/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043361/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057245/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
right: Coenzyme A
right: TG(12:0/16:0/16:1(9Z))
spontaneous: false
EC number: 2.3.1.20
left: DG(12:0/16:0/0:0)
left: Palmitoleyl-CoA
name: DG(12:0/16:0/0:0) + Palmitoleyl-CoA → Coenzyme A + TG(12:0/16:0/16:1(9Z))
conversion direction: LEFT_TO_RIGHT

Triacylglycerol lipase complex
type: Complex
component: Lipase 3
component: Lipase 4
component: Lipase 5
component: Sterol esterase TGL1
component: Lipase 2

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Lipase 3
type: ProteinReference
xref: Reference/UniProt P40308

Lipase 2
type: ProteinReference
xref: Reference/UniProt P54857

Lipase 5
type: ProteinReference
xref: Reference/UniProt Q12043

Lipase 4
type: ProteinReference
xref: Reference/UniProt P36165

Diacylglycerol O-acyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q08650

Reference/BioCyc PALMITYL-COA
type: UnificationXref
id: PALMITYL-COA
db: BioCyc

Sterol esterase TGL1
type: ProteinReference
xref: Reference/UniProt P34163

Reference/CAS 63-38-7
type: UnificationXref
id: 63-38-7
db: CAS

Monoglyceride lipase
type: ProteinReference
xref: Reference/UniProt P28321

Lauroyl-CoA
type: SmallMolecule
entity reference: Lauroyl-CoA

Reference/UniProt Q12043
type: UnificationXref
id: Q12043
db: UniProt

ChemicalStructure/PW C057245
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/CAS 18198-76-0
type: UnificationXref
id: 18198-76-0
db: CAS

Reference/HMDB HMDB0011564
type: UnificationXref
id: HMDB0011564
db: HMDB

Reference/ChemSpider 2341519
type: UnificationXref
id: 2341519
db: ChemSpider

DG(12:0/16:0/0:0)
type: SmallMolecule
entity reference: DG(12:0/16:0/0:0)

Reference/HMDB HMDB0006532
type: UnificationXref
id: HMDB0006532
db: HMDB

Dodecanoic acid
type: SmallMoleculeReference
xref: Reference/ChemSpider 3756
xref: Reference/KEGG Compound C02679
xref: Reference/CAS 143-07-7
xref: Reference/ChEBI CHEBI 30805
xref: Reference/HMDB HMDB0000638
xref: Reference/PubChem-compound 3893
chemical formula: C12H24O2
molecular weight: 200.17763
structure: ChemicalStructure/PW C000497

Reference/ChEBI CHEBI 62840
type: UnificationXref
id: CHEBI:62840
db: ChEBI

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Palmitoleyl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 53477852
xref: Reference/HMDB HMDB0006532
xref: Reference/ChEBI CHEBI 53152
xref: Reference/CAS 18198-76-0
chemical formula: C37H64N7O17P3S
molecular weight: 1003.3292
structure: ChemicalStructure/PW C002798

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Saccharomyces cerevisiae
type: BioSource
xref: Reference/TAXONOMY 4932

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Palmitic acid
type: SmallMolecule
entity reference: Palmitic acid

Palmitic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 985
xref: Reference/KEGG Compound C00249
xref: Reference/ChemSpider 960
xref: Reference/ChEBI CHEBI 15756
xref: Reference/BioCyc CPD-8475
xref: Reference/CAS 57-10-3
xref: Reference/HMDB HMDB0000220
chemical formula: C16H32O2
molecular weight: 256.24023
structure: ChemicalStructure/PW C000145

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Reference/UniProt P28321
type: UnificationXref
id: P28321
db: UniProt

Reference/ChEBI CHEBI 15521
type: UnificationXref
id: CHEBI:15521
db: ChEBI

Reference/KEGG Compound C00116
type: UnificationXref
id: C00116
db: KEGG Compound

Compound/PW C001031/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmitoyl-CoA
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 15525
type: UnificationXref
id: CHEBI:15525
db: ChEBI

Reference/UniProt P54857
type: UnificationXref
id: P54857
db: UniProt

Reference/ChEBI CHEBI 28716
type: UnificationXref
id: CHEBI:28716
db: ChEBI

ChemicalStructure/PW C042968
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCC(=O)OCC(O)COP(O)(O)=O

TG(12:0/16:0/16:1(9Z))
type: SmallMoleculeReference
chemical formula: C47H88O6
molecular weight: 748.6581
structure: ChemicalStructure/PW C057245

Reference/KEGG Compound C00112
type: UnificationXref
id: C00112
db: KEGG Compound

Reference/BioCyc LAUROYLCOA-CPD
type: UnificationXref
id: LAUROYLCOA-CPD
db: BioCyc

Reference/CAS 373-49-9
type: UnificationXref
id: 373-49-9
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

CDP
type: SmallMolecule
entity reference: CDP

ChemicalStructure/PW C002798
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/HMDB HMDB0001546
type: UnificationXref
id: HMDB0001546
db: HMDB

ChemicalStructure/PW C000497
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCC(O)=O

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

MG(16:0/0:0/0:0)
type: SmallMolecule
entity reference: MG(16:0/0:0/0:0)

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00249
type: UnificationXref
id: C00249
db: KEGG Compound

Reference/PubChem-compound 53477852
type: UnificationXref
id: 53477852
db: PubChem-compound

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/CAS 1763-10-6
type: UnificationXref
id: 1763-10-6
db: CAS

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/ChEBI CHEBI 75542
type: UnificationXref
id: CHEBI:75542
db: ChEBI

Glycerol
type: SmallMolecule
entity reference: Glycerol

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

Compound/PW C057245/Stoichiometry/1.0
type: Stoichiometry
physical entity: TG(12:0/16:0/16:1(9Z))
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000145
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCC(O)=O

Glycerol-3-phosphate O-acyltransferase 2
type: ProteinReference
xref: Reference/UniProt P36148

Reference/BioCyc CDP
type: UnificationXref
id: CDP
db: BioCyc

Glycerol-3-phosphate O-acyltransferase 1
type: ProteinReference
xref: Reference/UniProt P32784

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

Reference/HMDB HMDB0000220
type: UnificationXref
id: HMDB0000220
db: HMDB

Glycerol
type: SmallMoleculeReference
xref: Reference/PubChem-compound 753
xref: Reference/KEGG Compound C00116
xref: Reference/ChEBI CHEBI 17522
xref: Reference/CAS 56-81-5
xref: Reference/BioCyc GLYCEROL
xref: Reference/HMDB HMDB0000131
xref: Reference/ChemSpider 733
chemical formula: C3H8O3
molecular weight: 92.04734
structure: ChemicalStructure/PW C000085

Acyl-CoA:lyso-phospholipid acyltransferase
type: ProteinReference
xref: Reference/UniProt Q08548

Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
type: ProteinReference
xref: Reference/UniProt P33333

Lipase 4
type: ProteinReference
xref: Reference/UniProt P36165

Reference/KEGG Compound C02679
type: UnificationXref
id: C02679
db: KEGG Compound

Lipase 3
type: Protein
entity reference: Lipase 3

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

2.7.1.174
type: BiochemicalReaction
participant stoichiometry: Compound/PW C043361/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055520/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001189/Stoichiometry/1.0
right: CDP
right: PA(12:0/16:0)
right: Hydrogen Ion
spontaneous: false
EC number: 2.7.1.174
left: Cytidine triphosphate
left: DG(12:0/16:0/0:0)
name: Cytidine triphosphate + DG(12:0/16:0/0:0) → CDP + Hydrogen Ion + PA(12:0/16:0)
conversion direction: LEFT_TO_RIGHT

3.1.3.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043361/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055520/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: DG(12:0/16:0/0:0)
right: Phosphate
spontaneous: false
EC number: 3.1.3.4
left: Water
left: PA(12:0/16:0)
name: PA(12:0/16:0) + Water → DG(12:0/16:0/0:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

Palmitoleic acid
type: SmallMoleculeReference
xref: Reference/CAS 373-49-9
xref: Reference/BioCyc CPD-724
xref: Reference/PubChem-compound 445638
xref: Reference/KEGG Compound C08362
xref: Reference/HMDB HMDB0003229
xref: Reference/ChemSpider 393216
xref: Reference/ChEBI CHEBI 28716
chemical formula: C16H30O2
molecular weight: 254.22458
structure: ChemicalStructure/PW C001811

PA(12:0/16:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/ChEBI CHEBI 16337
chemical formula: C31H61O8P
molecular weight: 592.4104
structure: ChemicalStructure/PW C055520

Reference/PubChem-compound 3893
type: UnificationXref
id: 3893
db: PubChem-compound

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Lysophosphatidic acid:oleoyl-CoA acyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q06508

Lipase 5
type: ProteinReference
xref: Reference/UniProt Q12043

Phosphatidic acid phosphohydrolase 1
type: Protein
entity reference: Phosphatidic acid phosphohydrolase 1

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

CTP-dependent diacylglycerol kinase 1
type: Protein
entity reference: CTP-dependent diacylglycerol kinase 1

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Reference/ChemSpider 393216
type: UnificationXref
id: 393216
db: ChemSpider

Reference/ChEBI CHEBI 15756
type: UnificationXref
id: CHEBI:15756
db: ChEBI

Palmitoyl-CoA
type: SmallMoleculeReference
xref: Reference/PubChem-compound 15667
xref: Reference/ChemSpider 14902
xref: Reference/HMDB HMDB0001338
xref: Reference/ChEBI CHEBI 15525
xref: Reference/KEGG Compound C00154
xref: Reference/CAS 1763-10-6
xref: Reference/BioCyc PALMITYL-COA
chemical formula: C37H66N7O17P3S
molecular weight: 1005.34485
structure: ChemicalStructure/PW C001031

Reference/PubChem-compound 445638
type: UnificationXref
id: 445638
db: PubChem-compound

Triacylglycerol Metabolism TG(12:0/16:0/16:1(9Z))
type: Pathway
pathway order: PathwayEnzymeReaction/2451972
pathway order: PathwayEnzymeReaction/2451973
pathway order: PathwayEnzymeReaction/2451974
pathway order: PathwayEnzymeReaction/2451975
pathway order: PathwayEnzymeReaction/2451968
pathway order: PathwayEnzymeReaction/2451969
pathway order: PathwayEnzymeReaction/2451970
pathway order: PathwayEnzymeReaction/2451971
pathway component: 2.3.1.23
pathway component: ReactionCatalysis201058
pathway component: 3.1.1.13
pathway component: 2.7.1.174
pathway component: 2.3.1.20
pathway component: ReactionCatalysis201059
pathway component: 3.1.3.4
pathway component: 2.3.1.15
pathway component: 3.1.1.3
pathway component: 3.1.1.23
pathway component: ReactionCatalysis201060
pathway component: ReactionCatalysis201061
pathway component: ReactionCatalysis177066
pathway component: ReactionCatalysis177067
pathway component: ReactionCatalysis6971
pathway component: ReactionCatalysis6970
xref: Reference/PathWhiz PW007664
xref: Reference/SMPDB SMP0006806
organism: Saccharomyces cerevisiae

PA(12:0/16:0)
type: SmallMolecule
entity reference: PA(12:0/16:0)

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

Palmitoyl-CoA
type: SmallMolecule
entity reference: Palmitoyl-CoA

Reference/HMDB HMDB0001338
type: UnificationXref
id: HMDB0001338
db: HMDB

ReactionCatalysis177066
type: Catalysis
controller: Glycerol-3-phosphate O-acyltransferase
controlled: 2.3.1.15
control type: ACTIVATION

Compound/PW C042968/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPA(12:0/0:0)
stoichiometric coefficient: 1.0

ReactionCatalysis177067
type: Catalysis
controller: Lysophosphatidate acyltransferase
controlled: 2.3.1.23
control type: ACTIVATION

Compound/PW C002798/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmitoleyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc DIACYLGLYCEROL
type: UnificationXref
id: DIACYLGLYCEROL
db: BioCyc

Reference/UniProt P36148
type: UnificationXref
id: P36148
db: UniProt

Reference/CAS 32899-41-5
type: UnificationXref
id: 32899-41-5
db: CAS

Reference/KEGG Compound C00154
type: UnificationXref
id: C00154
db: KEGG Compound

ChemicalStructure/PW C001811
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCC\C=C/CCCCCCCC(O)=O

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

Compound/PW C055520/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(12:0/16:0)
stoichiometric coefficient: 1.0

ReactionCatalysis6971
type: Catalysis
controller: CTP-dependent diacylglycerol kinase 1
controlled: 2.7.1.174
control type: ACTIVATION

ReactionCatalysis6970
type: Catalysis
controller: Phosphatidic acid phosphohydrolase 1
controlled: 3.1.3.4
control type: ACTIVATION

Reference/HMDB HMDB0000131
type: UnificationXref
id: HMDB0000131
db: HMDB

Reference/PubChem-compound 753
type: UnificationXref
id: 753
db: PubChem-compound

Compound/PW C007160/Stoichiometry/1.0
type: Stoichiometry
physical entity: MG(16:0/0:0/0:0)
stoichiometric coefficient: 1.0

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/UniProt Q08650
type: UnificationXref
id: Q08650
db: UniProt

Reference/BioCyc GLYCEROL
type: UnificationXref
id: GLYCEROL
db: BioCyc

Reference/BioCyc CPD-8475
type: UnificationXref
id: CPD-8475
db: BioCyc

Reference/KEGG Compound C00165
type: UnificationXref
id: C00165
db: KEGG Compound

TG(12:0/16:0/16:1(9Z))
type: SmallMolecule
entity reference: TG(12:0/16:0/16:1(9Z))

3.1.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C043361/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007160/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000145/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Palmitic acid
right: Hydrogen Ion
right: MG(16:0/0:0/0:0)
spontaneous: false
EC number: 3.1.1.3
left: Water
left: DG(12:0/16:0/0:0)
name: DG(12:0/16:0/0:0) + Water → Hydrogen Ion + MG(16:0/0:0/0:0) + Palmitic acid
conversion direction: LEFT_TO_RIGHT

Compound/PW C001189/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

ChemicalStructure/PW C001031
type: ChemicalStructure
structure format: SMILES

Reference/UniProt P40308
type: UnificationXref
id: P40308
db: UniProt

2.3.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001031/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055520/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042968/Stoichiometry/1.0
right: Coenzyme A
right: PA(12:0/16:0)
spontaneous: false
EC number: 2.3.1.23
left: Palmitoyl-CoA
left: LysoPA(12:0/0:0)
name: LysoPA(12:0/0:0) + Palmitoyl-CoA → Coenzyme A + PA(12:0/16:0)
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 5902
type: UnificationXref
id: 5902
db: ChemSpider

Reference/ChemSpider 14902
type: UnificationXref
id: 14902
db: ChemSpider

Reference/UniProt P33333
type: UnificationXref
id: P33333
db: UniProt

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/SMPDB SMP0006806
type: UnificationXref
id: SMP0006806
db: SMPDB

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

CDP
type: SmallMoleculeReference
xref: Reference/ChemSpider 5902
xref: Reference/PubChem-compound 6132
xref: Reference/HMDB HMDB0001546
xref: Reference/ChEBI CHEBI 17239
xref: Reference/BioCyc CDP
xref: Reference/CAS 63-38-7
xref: Reference/KEGG Compound C00112
chemical formula: C9H15N3O11P2
molecular weight: 403.0182
structure: ChemicalStructure/PW C001189

MG(16:0/0:0/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 75542
xref: Reference/ChemSpider 2341519
xref: Reference/CAS 32899-41-5
xref: Reference/HMDB HMDB0011564
xref: Reference/PubChem-compound 3084463
chemical formula: C19H38O4
molecular weight: 330.277
structure: ChemicalStructure/PW C007160

Reference/CAS 57-10-3
type: UnificationXref
id: 57-10-3
db: CAS

Reference/UniProt P36165
type: UnificationXref
id: P36165
db: UniProt

ChemicalStructure/PW C043361
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 3084463
type: UnificationXref
id: 3084463
db: PubChem-compound

ChemicalStructure/PW C001928
type: ChemicalStructure
structure format: SMILES

Compound/PW C043361/Stoichiometry/1.0
type: Stoichiometry
physical entity: DG(12:0/16:0/0:0)
stoichiometric coefficient: 1.0

Reference/KEGG Compound C01832
type: UnificationXref
id: C01832
db: KEGG Compound

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Monoglyceride lipase
type: Protein
entity reference: Monoglyceride lipase

Reference/PubChem-compound 165436
type: UnificationXref
id: 165436
db: PubChem-compound

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

Reference/ChEBI CHEBI 30805
type: UnificationXref
id: CHEBI:30805
db: ChEBI

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Lipase 3
type: Protein
entity reference: Lipase 3

Lipase 4
type: Protein
entity reference: Lipase 4

ChemicalStructure/PW C007160
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@](O)(CO)COC(=O)CCCCCCCCCCCCCCC

Lipase 5
type: Protein
entity reference: Lipase 5

Diacylglycerol O-acyltransferase 1
type: Protein
entity reference: Diacylglycerol O-acyltransferase 1

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reference/UniProt Q12382
type: UnificationXref
id: Q12382
db: UniProt

Reference/UniProt P32784
type: UnificationXref
id: P32784
db: UniProt

Sterol esterase TGL1
type: Protein
entity reference: Sterol esterase TGL1

Lipase 2
type: Protein
entity reference: Lipase 2

Reference/CAS 143-07-7
type: UnificationXref
id: 143-07-7
db: CAS

Reference/ChemSpider 145018
type: UnificationXref
id: 145018
db: ChemSpider

ChemicalStructure/PW C055520
type: ChemicalStructure
structure format: SMILES

Phosphate
type: SmallMolecule
entity reference: Phosphate

Palmitoleyl-CoA
type: SmallMolecule
entity reference: Palmitoleyl-CoA

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Compound/PW C001928/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lauroyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 733
type: UnificationXref
id: 733
db: ChemSpider

ReactionCatalysis201060
type: Catalysis
controller: Lipase 3
controlled: 3.1.1.3
control type: ACTIVATION

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

ReactionCatalysis201061
type: Catalysis
controller: Monoglyceride lipase
controlled: 3.1.1.23
control type: ACTIVATION

Dodecanoic acid
type: SmallMolecule
entity reference: Dodecanoic acid

Reference/KEGG Compound C08362
type: UnificationXref
id: C08362
db: KEGG Compound

ChemicalStructure/PW C001189
type: ChemicalStructure
structure format: SMILES

Compound/PW C000145/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmitic acid
stoichiometric coefficient: 1.0

DG(12:0/16:0/0:0)
type: SmallMoleculeReference
xref: Reference/BioCyc DIACYLGLYCEROL
xref: Reference/KEGG Compound C00165
chemical formula: C31H60O5
molecular weight: 512.4441
structure: ChemicalStructure/PW C043361

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/UniProt P34163
type: UnificationXref
id: P34163
db: UniProt

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

LysoPA(12:0/0:0)
type: SmallMolecule
entity reference: LysoPA(12:0/0:0)

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChemSpider 960
type: UnificationXref
id: 960
db: ChemSpider

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

Reference/HMDB HMDB0003571
type: UnificationXref
id: HMDB0003571
db: HMDB

Compound/PW C000085/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Reference/UniProt P32567
type: UnificationXref
id: P32567
db: UniProt

Reference/PubChem-compound 985
type: UnificationXref
id: 985
db: PubChem-compound

Reference/ChEBI CHEBI 17522
type: UnificationXref
id: CHEBI:17522
db: ChEBI

Reference/TAXONOMY 4932
type: UnificationXref
id: 4932
db: TAXONOMY

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

LysoPA(12:0/0:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
xref: Reference/ChEBI CHEBI 62840
chemical formula: C15H31O7P
molecular weight: 354.18073
structure: ChemicalStructure/PW C042968

Reference/CAS 6244-92-4
type: UnificationXref
id: 6244-92-4
db: CAS

Reference/UniProt Q08548
type: UnificationXref
id: Q08548
db: UniProt

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/HMDB HMDB0003229
type: UnificationXref
id: HMDB0003229
db: HMDB

CTP-dependent diacylglycerol kinase 1
type: ProteinReference
xref: Reference/UniProt Q12382

Phosphatidic acid phosphohydrolase 1
type: ProteinReference
xref: Reference/UniProt P32567

Reference/PubChem-compound 15667
type: UnificationXref
id: 15667
db: PubChem-compound

Reference/ChemSpider 3756
type: UnificationXref
id: 3756
db: ChemSpider

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/BioCyc CPD-724
type: UnificationXref
id: CPD-724
db: BioCyc

Lysophosphatidic acid:oleoyl-CoA acyltransferase 1
type: Protein
entity reference: Lysophosphatidic acid:oleoyl-CoA acyltransferase 1

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

Reference/PathWhiz PW007664
type: UnificationXref
id: PW007664
db: PathWhiz

Lysophosphatidate acyltransferase
type: Complex
component: Lysophosphatidic acid:oleoyl-CoA acyltransferase 1
component: Acyl-CoA:lyso-phospholipid acyltransferase
component: Lipase 4
component: Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
component: Lipase 5

Acyl-CoA:lyso-phospholipid acyltransferase
type: Protein
entity reference: Acyl-CoA:lyso-phospholipid acyltransferase

Lipase 4
type: Protein
entity reference: Lipase 4

ReactionCatalysis201058
type: Catalysis
controller: Diacylglycerol O-acyltransferase 1
controlled: 2.3.1.20
control type: ACTIVATION

Glycerol-3-phosphate O-acyltransferase
type: Complex
component: Glycerol-3-phosphate O-acyltransferase 2
component: Glycerol-3-phosphate O-acyltransferase 1

Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
type: Protein
entity reference: Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase

Reference/ChEBI CHEBI 53152
type: UnificationXref
id: CHEBI:53152
db: ChEBI

ReactionCatalysis201059
type: Catalysis
controller: Triacylglycerol lipase complex
controlled: 3.1.1.13
control type: ACTIVATION

Lipase 5
type: Protein
entity reference: Lipase 5

Reference/HMDB HMDB0000638
type: UnificationXref
id: HMDB0000638
db: HMDB

2.3.1.15
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042968/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001928/Stoichiometry/1.0
right: Coenzyme A
right: LysoPA(12:0/0:0)
spontaneous: false
EC number: 2.3.1.15
left: Lauroyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Lauroyl-CoA → Coenzyme A + LysoPA(12:0/0:0)
conversion direction: LEFT_TO_RIGHT

3.1.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007160/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000497/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000085/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Glycerol
right: Dodecanoic acid
right: Hydrogen Ion
spontaneous: false
EC number: 3.1.1.23
left: Water
left: MG(16:0/0:0/0:0)
name: MG(16:0/0:0/0:0) + Water → Dodecanoic acid + Glycerol + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000085
type: ChemicalStructure
structure format: SMILES
structure data: OCC(O)CO

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Compound/PW C001811/Stoichiometry/1.0
type: Stoichiometry
physical entity: Palmitoleic acid
stoichiometric coefficient: 1.0

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Lipase 3
type: ProteinReference
xref: Reference/UniProt P40308

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O