Glycerol-3-phosphate O-acyltransferase 2
type: Protein
entity reference: Glycerol-3-phosphate O-acyltransferase 2

Glycerol-3-phosphate O-acyltransferase 1
type: Protein
entity reference: Glycerol-3-phosphate O-acyltransferase 1

PA(10:0/22:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/HMDB HMDB0114777
xref: Reference/ChEBI CHEBI 16337
chemical formula: C35H69O8P
molecular weight: 648.473
structure: ChemicalStructure/PW C062192

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

3.1.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007160/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000754/Stoichiometry/1.0
participant stoichiometry: Compound/PW C054857/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Hydrogen Ion
right: Behenic acid
right: MG(16:0/0:0/0:0)
spontaneous: false
EC number: 3.1.1.3
left: Water
left: DG(10:0/22:0/0:0)
name: DG(10:0/22:0/0:0) + Water → Behenic acid + Hydrogen Ion + MG(16:0/0:0/0:0)
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

2.7.1.174
type: BiochemicalReaction
participant stoichiometry: Compound/PW C062192/Stoichiometry/1.0
participant stoichiometry: Compound/PW C054857/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001189/Stoichiometry/1.0
right: CDP
right: Hydrogen Ion
right: PA(10:0/22:0)
spontaneous: false
EC number: 2.7.1.174
left: Cytidine triphosphate
left: DG(10:0/22:0/0:0)
name: Cytidine triphosphate + DG(10:0/22:0/0:0) → CDP + Hydrogen Ion + PA(10:0/22:0)
conversion direction: LEFT_TO_RIGHT

3.1.3.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C062192/Stoichiometry/1.0
participant stoichiometry: Compound/PW C054857/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: DG(10:0/22:0/0:0)
right: Phosphate
spontaneous: false
EC number: 3.1.3.4
left: Water
left: PA(10:0/22:0)
name: PA(10:0/22:0) + Water → DG(10:0/22:0/0:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

Capric acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 2969
xref: Reference/BioCyc 3-OXODODECANOATE
xref: Reference/ChEBI CHEBI 30813
xref: Reference/HMDB HMDB0000511
xref: Reference/ChemSpider 2863
xref: Reference/KEGG Compound C01571
xref: Reference/CAS 334-48-5
chemical formula: C10H20O2
molecular weight: 172.14633
structure: ChemicalStructure/PW C000391

Reference/UniProt Q06508
type: UnificationXref
id: Q06508
db: UniProt

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/CAS 56-81-5
type: UnificationXref
id: 56-81-5
db: CAS

Reference/KEGG Compound C08281
type: UnificationXref
id: C08281
db: KEGG Compound

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6132
type: UnificationXref
id: 6132
db: PubChem-compound

Reference/BioCyc CPD-10279
type: UnificationXref
id: CPD-10279
db: BioCyc

Reference/ChEBI CHEBI 17239
type: UnificationXref
id: CHEBI:17239
db: ChEBI

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Triacylglycerol lipase complex
type: Complex
component: Lipase 3
component: Lipase 4
component: Lipase 5
component: Sterol esterase TGL1
component: Lipase 2

Reference/BioCyc 3-OXODODECANOATE
type: UnificationXref
id: 3-OXODODECANOATE
db: BioCyc

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/HMDB HMDB0006404
type: UnificationXref
id: HMDB0006404
db: HMDB

ChemicalStructure/PW C108356
type: ChemicalStructure
structure format: SMILES

Lipase 3
type: ProteinReference
xref: Reference/UniProt P40308

Lipase 2
type: ProteinReference
xref: Reference/UniProt P54857

Compound/PW C055362/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPA(10:0/0:0)
stoichiometric coefficient: 1.0

Lipase 5
type: ProteinReference
xref: Reference/UniProt Q12043

Lipase 4
type: ProteinReference
xref: Reference/UniProt P36165

Diacylglycerol O-acyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q08650

Sterol esterase TGL1
type: ProteinReference
xref: Reference/UniProt P34163

Reference/CAS 63-38-7
type: UnificationXref
id: 63-38-7
db: CAS

Monoglyceride lipase
type: ProteinReference
xref: Reference/UniProt P28321

Reference/ChemSpider 7923
type: UnificationXref
id: 7923
db: ChemSpider

Reference/UniProt Q12043
type: UnificationXref
id: Q12043
db: UniProt

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/HMDB HMDB0011564
type: UnificationXref
id: HMDB0011564
db: HMDB

Reference/ChemSpider 2341519
type: UnificationXref
id: 2341519
db: ChemSpider

Capric acid
type: SmallMolecule
entity reference: Capric acid

Reference/CAS 24330-89-0
type: UnificationXref
id: 24330-89-0
db: CAS

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/PubChem-compound 8215
type: UnificationXref
id: 8215
db: PubChem-compound

Saccharomyces cerevisiae
type: BioSource
xref: Reference/TAXONOMY 4932

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C002742
type: ChemicalStructure
structure format: SMILES

pentacosanoic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 39420
xref: Reference/CAS 506-38-7
xref: Reference/HMDB HMDB0002361
xref: Reference/PubChem-compound 10468
xref: Reference/ChemSpider 10036
chemical formula: C25H50O2
molecular weight: 382.38107
structure: ChemicalStructure/PW C001593

Reference/HMDB HMDB0114777
type: UnificationXref
id: HMDB0114777
db: HMDB

Reference/CAS 506-38-7
type: UnificationXref
id: 506-38-7
db: CAS

pentacosanoic acid
type: SmallMolecule
entity reference: pentacosanoic acid

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Compound/PW C108356/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pentacosanoyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 10036
type: UnificationXref
id: 10036
db: ChemSpider

Reference/UniProt P28321
type: UnificationXref
id: P28321
db: UniProt

Compound/PW C000754/Stoichiometry/1.0
type: Stoichiometry
physical entity: Behenic acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00116
type: UnificationXref
id: C00116
db: KEGG Compound

Reference/ChEBI CHEBI 16975
type: UnificationXref
id: CHEBI:16975
db: ChEBI

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/UniProt P54857
type: UnificationXref
id: P54857
db: UniProt

ChemicalStructure/PW C055362
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCC(=O)OCC(O)COP(O)(O)=O

Reference/KEGG Compound C00112
type: UnificationXref
id: C00112
db: KEGG Compound

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

CDP
type: SmallMolecule
entity reference: CDP

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/HMDB HMDB0001546
type: UnificationXref
id: HMDB0001546
db: HMDB

2.3.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C062192/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055362/Stoichiometry/1.0
participant stoichiometry: Compound/PW C008122/Stoichiometry/1.0
right: Coenzyme A
right: PA(10:0/22:0)
spontaneous: false
EC number: 2.3.1.23
left: LysoPA(10:0/0:0)
left: Docosanoyl-CoA
name: Docosanoyl-CoA + LysoPA(10:0/0:0) → Coenzyme A + PA(10:0/22:0)
conversion direction: LEFT_TO_RIGHT

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

MG(16:0/0:0/0:0)
type: SmallMolecule
entity reference: MG(16:0/0:0/0:0)

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Behenic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 28941
xref: Reference/CAS 112-85-6
xref: Reference/ChemSpider 7923
xref: Reference/HMDB HMDB0000944
xref: Reference/KEGG Compound C08281
xref: Reference/PubChem-compound 8215
chemical formula: C22H44O2
molecular weight: 340.33414
structure: ChemicalStructure/PW C000754

Compound/PW C054857/Stoichiometry/1.0
type: Stoichiometry
physical entity: DG(10:0/22:0/0:0)
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/PubChem-compound 440615
type: UnificationXref
id: 440615
db: PubChem-compound

Reference/KEGG Compound C01571
type: UnificationXref
id: C01571
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/ChEBI CHEBI 75542
type: UnificationXref
id: CHEBI:75542
db: ChEBI

Glycerol
type: SmallMolecule
entity reference: Glycerol

2.3.1.15
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002742/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055362/Stoichiometry/1.0
right: Coenzyme A
right: LysoPA(10:0/0:0)
spontaneous: false
EC number: 2.3.1.15
left: Decanoyl-CoA
left: Glycerol 3-phosphate
name: Decanoyl-CoA + Glycerol 3-phosphate → Coenzyme A + LysoPA(10:0/0:0)
conversion direction: LEFT_TO_RIGHT

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

ChemicalStructure/PW C001593
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCCCCCCCCCCC(O)=O

Glycerol-3-phosphate O-acyltransferase 2
type: ProteinReference
xref: Reference/UniProt P36148

Docosanoyl-CoA
type: SmallMolecule
entity reference: Docosanoyl-CoA

Reference/BioCyc CDP
type: UnificationXref
id: CDP
db: BioCyc

PA(10:0/22:0)
type: SmallMolecule
entity reference: PA(10:0/22:0)

Glycerol-3-phosphate O-acyltransferase 1
type: ProteinReference
xref: Reference/UniProt P32784

Compound/PW C008122/Stoichiometry/1.0
type: Stoichiometry
physical entity: Docosanoyl-CoA
stoichiometric coefficient: 1.0

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

Docosanoyl-CoA
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0012930
xref: Reference/KEGG Compound C16528
xref: Reference/ChEBI CHEBI 65088
xref: Reference/BioCyc CPD-10279
xref: Reference/PubChem-compound 168166
xref: Reference/CAS 24330-89-0
chemical formula: C43H78N7O17P3S
molecular weight: 1089.4387
structure: ChemicalStructure/PW C008122

Glycerol
type: SmallMoleculeReference
xref: Reference/PubChem-compound 753
xref: Reference/KEGG Compound C00116
xref: Reference/ChEBI CHEBI 17522
xref: Reference/CAS 56-81-5
xref: Reference/BioCyc GLYCEROL
xref: Reference/HMDB HMDB0000131
xref: Reference/ChemSpider 733
chemical formula: C3H8O3
molecular weight: 92.04734
structure: ChemicalStructure/PW C000085

Acyl-CoA:lyso-phospholipid acyltransferase
type: ProteinReference
xref: Reference/UniProt Q08548

Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
type: ProteinReference
xref: Reference/UniProt P33333

Lipase 4
type: ProteinReference
xref: Reference/UniProt P36165

Reference/ChEBI CHEBI 65088
type: UnificationXref
id: CHEBI:65088
db: ChEBI

Lipase 3
type: Protein
entity reference: Lipase 3

Behenic acid
type: SmallMolecule
entity reference: Behenic acid

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

Reference/KEGG Compound C05274
type: UnificationXref
id: C05274
db: KEGG Compound

Reference/ChEBI CHEBI 28941
type: UnificationXref
id: CHEBI:28941
db: ChEBI

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Lysophosphatidic acid:oleoyl-CoA acyltransferase 1
type: ProteinReference
xref: Reference/UniProt Q06508

Lipase 5
type: ProteinReference
xref: Reference/UniProt Q12043

Compound/PW C057412/Stoichiometry/1.0
type: Stoichiometry
physical entity: TG(10:0/22:0/25:0)
stoichiometric coefficient: 1.0

Reference/CAS 334-48-5
type: UnificationXref
id: 334-48-5
db: CAS

Phosphatidic acid phosphohydrolase 1
type: Protein
entity reference: Phosphatidic acid phosphohydrolase 1

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

CTP-dependent diacylglycerol kinase 1
type: Protein
entity reference: CTP-dependent diacylglycerol kinase 1

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Reference/ChemSpider 389510
type: UnificationXref
id: 389510
db: ChemSpider

Reference/CAS 1264-57-9
type: UnificationXref
id: 1264-57-9
db: CAS

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

ChemicalStructure/PW C054857
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis177066
type: Catalysis
controller: Glycerol-3-phosphate O-acyltransferase
controlled: 2.3.1.15
control type: ACTIVATION

ReactionCatalysis177067
type: Catalysis
controller: Lysophosphatidate acyltransferase
controlled: 2.3.1.23
control type: ACTIVATION

Reference/ChEBI CHEBI 28493
type: UnificationXref
id: CHEBI:28493
db: ChEBI

Reference/SMPDB SMP0007025
type: UnificationXref
id: SMP0007025
db: SMPDB

Reference/BioCyc DIACYLGLYCEROL
type: UnificationXref
id: DIACYLGLYCEROL
db: BioCyc

Reference/CAS 112-85-6
type: UnificationXref
id: 112-85-6
db: CAS

Reference/UniProt P36148
type: UnificationXref
id: P36148
db: UniProt

Reference/CAS 32899-41-5
type: UnificationXref
id: 32899-41-5
db: CAS

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis6971
type: Catalysis
controller: CTP-dependent diacylglycerol kinase 1
controlled: 2.7.1.174
control type: ACTIVATION

ReactionCatalysis6970
type: Catalysis
controller: Phosphatidic acid phosphohydrolase 1
controlled: 3.1.3.4
control type: ACTIVATION

Reference/HMDB HMDB0000131
type: UnificationXref
id: HMDB0000131
db: HMDB

Reference/PubChem-compound 753
type: UnificationXref
id: 753
db: PubChem-compound

Compound/PW C007160/Stoichiometry/1.0
type: Stoichiometry
physical entity: MG(16:0/0:0/0:0)
stoichiometric coefficient: 1.0

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/UniProt Q08650
type: UnificationXref
id: Q08650
db: UniProt

Reference/BioCyc GLYCEROL
type: UnificationXref
id: GLYCEROL
db: BioCyc

Reference/KEGG Compound C00165
type: UnificationXref
id: C00165
db: KEGG Compound

Reference/PathWhiz PW007883
type: UnificationXref
id: PW007883
db: PathWhiz

Decanoyl-CoA
type: SmallMolecule
entity reference: Decanoyl-CoA

Compound/PW C001189/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/HMDB HMDB0093011
type: UnificationXref
id: HMDB0093011
db: HMDB

Decanoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05274
xref: Reference/CAS 1264-57-9
xref: Reference/HMDB HMDB0006404
xref: Reference/PubChem-compound 440615
xref: Reference/ChEBI CHEBI 28493
xref: Reference/ChemSpider 389510
chemical formula: C31H54N7O17P3S
molecular weight: 921.251
structure: ChemicalStructure/PW C002742

DG(10:0/22:0/0:0)
type: SmallMoleculeReference
xref: Reference/BioCyc DIACYLGLYCEROL
xref: Reference/HMDB HMDB0093011
xref: Reference/KEGG Compound C00165
chemical formula: C35H68O5
molecular weight: 568.50665
structure: ChemicalStructure/PW C054857

Reference/UniProt P40308
type: UnificationXref
id: P40308
db: UniProt

Reference/ChemSpider 5902
type: UnificationXref
id: 5902
db: ChemSpider

Reference/HMDB HMDB0012930
type: UnificationXref
id: HMDB0012930
db: HMDB

Reference/UniProt P33333
type: UnificationXref
id: P33333
db: UniProt

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/HMDB HMDB0000944
type: UnificationXref
id: HMDB0000944
db: HMDB

Reference/PubChem-compound 10468
type: UnificationXref
id: 10468
db: PubChem-compound

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Reference/ChEBI CHEBI 30813
type: UnificationXref
id: CHEBI:30813
db: ChEBI

CDP
type: SmallMoleculeReference
xref: Reference/ChemSpider 5902
xref: Reference/PubChem-compound 6132
xref: Reference/HMDB HMDB0001546
xref: Reference/ChEBI CHEBI 17239
xref: Reference/BioCyc CDP
xref: Reference/CAS 63-38-7
xref: Reference/KEGG Compound C00112
chemical formula: C9H15N3O11P2
molecular weight: 403.0182
structure: ChemicalStructure/PW C001189

MG(16:0/0:0/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 75542
xref: Reference/ChemSpider 2341519
xref: Reference/CAS 32899-41-5
xref: Reference/HMDB HMDB0011564
xref: Reference/PubChem-compound 3084463
chemical formula: C19H38O4
molecular weight: 330.277
structure: ChemicalStructure/PW C007160

ChemicalStructure/PW C000391
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCC(O)=O

Reference/UniProt P36165
type: UnificationXref
id: P36165
db: UniProt

Reference/PubChem-compound 3084463
type: UnificationXref
id: 3084463
db: PubChem-compound

Compound/PW C062192/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(10:0/22:0)
stoichiometric coefficient: 1.0

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChemSpider 2863
type: UnificationXref
id: 2863
db: ChemSpider

Monoglyceride lipase
type: Protein
entity reference: Monoglyceride lipase

ChemicalStructure/PW C057412
type: ChemicalStructure
structure format: SMILES

Compound/PW C001593/Stoichiometry/1.0
type: Stoichiometry
physical entity: pentacosanoic acid
stoichiometric coefficient: 1.0

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

Reference/KEGG Compound C16528
type: UnificationXref
id: C16528
db: KEGG Compound

Pentacosanoyl-CoA
type: SmallMoleculeReference
chemical formula: C46H84N7O17P3S
molecular weight: 1131.4857
structure: ChemicalStructure/PW C108356

Compound/PW C002742/Stoichiometry/1.0
type: Stoichiometry
physical entity: Decanoyl-CoA
stoichiometric coefficient: 1.0

Pentacosanoyl-CoA
type: SmallMolecule
entity reference: Pentacosanoyl-CoA

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Lipase 3
type: Protein
entity reference: Lipase 3

Lipase 4
type: Protein
entity reference: Lipase 4

ChemicalStructure/PW C007160
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@](O)(CO)COC(=O)CCCCCCCCCCCCCCC

Lipase 5
type: Protein
entity reference: Lipase 5

Diacylglycerol O-acyltransferase 1
type: Protein
entity reference: Diacylglycerol O-acyltransferase 1

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reference/UniProt Q12382
type: UnificationXref
id: Q12382
db: UniProt

Reference/UniProt P32784
type: UnificationXref
id: P32784
db: UniProt

Sterol esterase TGL1
type: Protein
entity reference: Sterol esterase TGL1

Lipase 2
type: Protein
entity reference: Lipase 2

Phosphate
type: SmallMolecule
entity reference: Phosphate

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 733
type: UnificationXref
id: 733
db: ChemSpider

ReactionCatalysis201060
type: Catalysis
controller: Lipase 3
controlled: 3.1.1.3
control type: ACTIVATION

Compound/PW C000391/Stoichiometry/1.0
type: Stoichiometry
physical entity: Capric acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

ReactionCatalysis201061
type: Catalysis
controller: Monoglyceride lipase
controlled: 3.1.1.23
control type: ACTIVATION

ChemicalStructure/PW C001189
type: ChemicalStructure
structure format: SMILES

Triacylglycerol Metabolism TG(10:0/22:0/25:0)
type: Pathway
pathway order: PathwayEnzymeReaction/2457209
pathway order: PathwayEnzymeReaction/2457208
pathway order: PathwayEnzymeReaction/2457210
pathway order: PathwayEnzymeReaction/2457214
pathway order: PathwayEnzymeReaction/2457213
pathway order: PathwayEnzymeReaction/2457212
pathway order: PathwayEnzymeReaction/2457211
pathway order: PathwayEnzymeReaction/2457215
pathway component: ReactionCatalysis201058
pathway component: 3.1.1.23
pathway component: ReactionCatalysis201059
pathway component: 3.1.1.3
pathway component: 2.3.1.20
pathway component: 2.7.1.174
pathway component: 3.1.1.13
pathway component: 3.1.3.4
pathway component: ReactionCatalysis201060
pathway component: ReactionCatalysis201061
pathway component: 2.3.1.15
pathway component: 2.3.1.23
pathway component: ReactionCatalysis177066
pathway component: ReactionCatalysis177067
pathway component: ReactionCatalysis6971
pathway component: ReactionCatalysis6970
xref: Reference/PathWhiz PW007883
xref: Reference/SMPDB SMP0007025
organism: Saccharomyces cerevisiae

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/UniProt P34163
type: UnificationXref
id: P34163
db: UniProt

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

3.1.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000391/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007160/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000085/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Glycerol
right: Capric acid
right: Hydrogen Ion
spontaneous: false
EC number: 3.1.1.23
left: Water
left: MG(16:0/0:0/0:0)
name: MG(16:0/0:0/0:0) + Water → Capric acid + Glycerol + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

TG(10:0/22:0/25:0)
type: SmallMoleculeReference
chemical formula: C60H116O6
molecular weight: 932.8772
structure: ChemicalStructure/PW C057412

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

Reference/HMDB HMDB0002361
type: UnificationXref
id: HMDB0002361
db: HMDB

Compound/PW C000085/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol
stoichiometric coefficient: 1.0

DG(10:0/22:0/0:0)
type: SmallMolecule
entity reference: DG(10:0/22:0/0:0)

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Reference/UniProt P32567
type: UnificationXref
id: P32567
db: UniProt

Reference/ChEBI CHEBI 17522
type: UnificationXref
id: CHEBI:17522
db: ChEBI

Reference/TAXONOMY 4932
type: UnificationXref
id: 4932
db: TAXONOMY

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

Reference/PubChem-compound 168166
type: UnificationXref
id: 168166
db: PubChem-compound

LysoPA(10:0/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16975
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
chemical formula: C13H27O7P
molecular weight: 326.14944
structure: ChemicalStructure/PW C055362

Reference/UniProt Q08548
type: UnificationXref
id: Q08548
db: UniProt

Reference/PubChem-compound 2969
type: UnificationXref
id: 2969
db: PubChem-compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

TG(10:0/22:0/25:0)
type: SmallMolecule
entity reference: TG(10:0/22:0/25:0)

Reference/HMDB HMDB0000511
type: UnificationXref
id: HMDB0000511
db: HMDB

CTP-dependent diacylglycerol kinase 1
type: ProteinReference
xref: Reference/UniProt Q12382

Phosphatidic acid phosphohydrolase 1
type: ProteinReference
xref: Reference/UniProt P32567

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/ChEBI CHEBI 39420
type: UnificationXref
id: CHEBI:39420
db: ChEBI

Lysophosphatidic acid:oleoyl-CoA acyltransferase 1
type: Protein
entity reference: Lysophosphatidic acid:oleoyl-CoA acyltransferase 1

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

LysoPA(10:0/0:0)
type: SmallMolecule
entity reference: LysoPA(10:0/0:0)

Lysophosphatidate acyltransferase
type: Complex
component: Lysophosphatidic acid:oleoyl-CoA acyltransferase 1
component: Acyl-CoA:lyso-phospholipid acyltransferase
component: Lipase 4
component: Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
component: Lipase 5

Acyl-CoA:lyso-phospholipid acyltransferase
type: Protein
entity reference: Acyl-CoA:lyso-phospholipid acyltransferase

Lipase 4
type: Protein
entity reference: Lipase 4

ReactionCatalysis201058
type: Catalysis
controller: Diacylglycerol O-acyltransferase 1
controlled: 2.3.1.20
control type: ACTIVATION

Glycerol-3-phosphate O-acyltransferase
type: Complex
component: Glycerol-3-phosphate O-acyltransferase 2
component: Glycerol-3-phosphate O-acyltransferase 1

Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase
type: Protein
entity reference: Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase

ReactionCatalysis201059
type: Catalysis
controller: Triacylglycerol lipase complex
controlled: 3.1.1.13
control type: ACTIVATION

ChemicalStructure/PW C000754
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCCCCCCCC(O)=O

Lipase 5
type: Protein
entity reference: Lipase 5

2.3.1.20
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C054857/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108356/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057412/Stoichiometry/1.0
right: Coenzyme A
right: TG(10:0/22:0/25:0)
spontaneous: false
EC number: 2.3.1.20
left: Pentacosanoyl-CoA
left: DG(10:0/22:0/0:0)
name: DG(10:0/22:0/0:0) + Pentacosanoyl-CoA → Coenzyme A + TG(10:0/22:0/25:0)
conversion direction: LEFT_TO_RIGHT

3.1.1.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C054857/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001593/Stoichiometry/1.0
participant stoichiometry: Compound/PW C057412/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Hydrogen Ion
right: pentacosanoic acid
right: DG(10:0/22:0/0:0)
spontaneous: false
EC number: 3.1.1.13
left: Water
left: TG(10:0/22:0/25:0)
name: TG(10:0/22:0/25:0) + Water → DG(10:0/22:0/0:0) + Hydrogen Ion + pentacosanoic acid
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000085
type: ChemicalStructure
structure format: SMILES
structure data: OCC(O)CO

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

ChemicalStructure/PW C062192
type: ChemicalStructure
structure format: SMILES

Lipase 3
type: ProteinReference
xref: Reference/UniProt P40308

ChemicalStructure/PW C008122
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O