D-Fructose 2,6-bisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001047
xref: Reference/CAS 79082-92-1
xref: Reference/BioCyc CPD-535
xref: Reference/ChEBI CHEBI 28602
xref: Reference/ChemSpider 94762
xref: Reference/KEGG Compound C00665
xref: Reference/PubChem-compound 105021
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C000825

Compound/PW C001134 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc CPD-535
type: UnificationXref
id: CPD-535
db: BioCyc

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/TAXONOMY 3702
type: UnificationXref
id: 3702
db: TAXONOMY

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

SubPathwayInteraction4831
type: Interaction
name: SubPathwayReaction
name: SubPathway4831Reaction
participant: α-D-Glucose

SubPathwayInteraction4830
type: Interaction
name: SubPathway4830Reaction
name: SubPathwayReaction
participant: D-Glyceraldehyde 3-phosphate
participant: β-D-Fructose 6-phosphate

Glyceraldehyde
type: SmallMoleculeReference
xref: Reference/ChemSpider 731
xref: Reference/PubChem-compound 751
xref: Reference/ChEBI CHEBI 5445
xref: Reference/CAS 56-82-6
xref: Reference/BioCyc GLYCERALD
xref: Reference/HMDB HMDB0001051
xref: Reference/KEGG Compound C02154
chemical formula: C3H6O3
molecular weight: 90.03169
structure: ChemicalStructure/PW C000828

Reference/KEGG Compound C00794
type: UnificationXref
id: C00794
db: KEGG Compound

Reference/ChEBI CHEBI 5445
type: UnificationXref
id: CHEBI:5445
db: ChEBI

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Compound/PW C000833 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fructose 1,6-bisphosphate
stoichiometric coefficient: 1.0

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
type: Protein
cellular location: Cytosol
entity reference: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/KEGG Compound C01094
type: UnificationXref
id: C01094
db: KEGG Compound

Fructose 1,6-bisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001058
xref: Reference/BioCyc FRUCTOSE-16-DIPHOSPHATE
xref: Reference/CAS 488-69-7
xref: Reference/ChEBI CHEBI 16905
xref: Reference/ChemSpider 393165
xref: Reference/KEGG Compound C00354
xref: Reference/PubChem-compound 445557
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C000833

Reference/PubChem-compound 439709
type: UnificationXref
id: 439709
db: PubChem-compound

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/CAS 53188-23-1
type: UnificationXref
id: 53188-23-1
db: CAS

D-Fructose 2,6-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Fructose 2,6-bisphosphate

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

pyrophosphate--fructose 6-phosphate 1-phosphotransferase
type: Complex
cellular location: Cytosol
component: pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta 1
component: pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha 1

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Sorbitol
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5780
xref: Reference/HMDB HMDB0000247
xref: Reference/ChEBI CHEBI 17924
xref: Reference/ChemSpider 5576
xref: Reference/CAS 50-70-4
xref: Reference/KEGG Compound C00794
chemical formula: C6H14O6
molecular weight: 182.07904
structure: ChemicalStructure/PW C000168

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/HMDB HMDB0001076
type: UnificationXref
id: HMDB0001076
db: HMDB

Reference/HMDB HMDB0000660
type: UnificationXref
id: HMDB0000660
db: HMDB

Compound/PW C000847 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fructose 1-phosphate
stoichiometric coefficient: 1.0

5.3.1.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001851 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517 Cytosol/Stoichiometry/1.0
right: D-Fructose
spontaneous: false
EC number: 5.3.1.5
left: α-D-Glucose
name: α-D-Glucose ↔ D-Fructose
conversion direction: REVERSIBLE

1.1.1.14
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000168 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517 Cytosol/Stoichiometry/1.0
right: D-Fructose
right: Hydrogen Ion
right: NADH
spontaneous: false
EC number: 1.1.1.14
left: NAD
left: Sorbitol
name: NAD + Sorbitol ↔ D-Fructose + Hydrogen Ion + NADH
conversion direction: REVERSIBLE

hexokinase-1
type: ProteinReference
xref: Reference/UniProt Q42525
organism: Arabidopsis thaliana

Reaction48135
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002021 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: β-D-Fructose 6-phosphate
spontaneous: false
left: D-Fructose
left: Adenosine triphosphate
name: Adenosine triphosphate + D-Fructose → Adenosine diphosphate + β-D-Fructose 6-phosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002021 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000517 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: β-D-Fructose 6-phosphate
spontaneous: false
EC number: 2.7.1.4
left: D-Fructose
left: Adenosine triphosphate
name: Adenosine triphosphate + D-Fructose → Adenosine diphosphate + β-D-Fructose 6-phosphate
conversion direction: LEFT_TO_RIGHT

NADH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADH

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

3.1.3.46
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002021 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000825 Cytosol/Stoichiometry/1.0
right: Phosphate
right: β-D-Fructose 6-phosphate
spontaneous: false
EC number: 3.1.3.46
left: D-Fructose 2,6-bisphosphate
left: Water
name: D-Fructose 2,6-bisphosphate + Water → Phosphate + β-D-Fructose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

2.7.1.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002021 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000833 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Fructose 1,6-bisphosphate
spontaneous: false
EC number: 2.7.1.11
left: Adenosine triphosphate
left: β-D-Fructose 6-phosphate
name: Adenosine triphosphate + β-D-Fructose 6-phosphate → Adenosine diphosphate + Fructose 1,6-bisphosphate
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C05345
type: UnificationXref
id: C05345
db: KEGG Compound

3.1.3.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000833 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002021 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: β-D-Fructose 6-phosphate
spontaneous: false
EC number: 3.1.3.11
left: Fructose 1,6-bisphosphate
left: Water
name: Fructose 1,6-bisphosphate + Water → Phosphate + β-D-Fructose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
type: UnificationXref
id: ALPHA-GLUCOSE-16-BISPHOSPHATE
db: BioCyc

Reference/CAS 56-82-6
type: UnificationXref
id: 56-82-6
db: CAS

Reference/ChEBI CHEBI 16905
type: UnificationXref
id: CHEBI:16905
db: ChEBI

xylose isomerase
type: ProteinReference
xref: Reference/UniProt Q9FKK7
organism: Arabidopsis thaliana

Reference/PathWhiz PW000839
type: UnificationXref
id: PW000839
db: PathWhiz

sorbitol dehydrogenase
type: ProteinReference
xref: Reference/UniProt Q9FJ95
organism: Arabidopsis thaliana

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

2.7.1.90
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002021 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000833 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Fructose 1,6-bisphosphate
spontaneous: false
EC number: 2.7.1.90
left: Pyrophosphate
left: β-D-Fructose 6-phosphate
name: Pyrophosphate + β-D-Fructose 6-phosphate ↔ Fructose 1,6-bisphosphate + Phosphate
conversion direction: REVERSIBLE

4.1.2.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000833 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869 Cytosol/Stoichiometry/1.0
right: Dihydroxyacetone phosphate
right: D-Glyceraldehyde 3-phosphate
spontaneous: false
EC number: 4.1.2.13
left: Fructose 1,6-bisphosphate
name: Fructose 1,6-bisphosphate ↔ D-Glyceraldehyde 3-phosphate + Dihydroxyacetone phosphate
conversion direction: REVERSIBLE

5.3.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869 Cytosol/Stoichiometry/1.0
right: Dihydroxyacetone phosphate
spontaneous: false
EC number: 5.3.1.1
left: D-Glyceraldehyde 3-phosphate
name: D-Glyceraldehyde 3-phosphate ↔ Dihydroxyacetone phosphate
conversion direction: REVERSIBLE

pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha 1
type: Protein
cellular location: Cytosol
entity reference: pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha 1

2.7.1.28
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000828 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: D-Glyceraldehyde 3-phosphate
spontaneous: false
EC number: 2.7.1.28
left: Adenosine triphosphate
left: Glyceraldehyde
name: Adenosine triphosphate + Glyceraldehyde → Adenosine diphosphate + D-Glyceraldehyde 3-phosphate
conversion direction: LEFT_TO_RIGHT

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway4830
pathway component: SubPathwayInteraction4830
xref: Reference/SMPDB SMP0000859
xref: Reference/PathWhiz PW000839
name: SubPathway

Reference/ChemSpider 709
type: UnificationXref
id: 709
db: ChemSpider

Reaction48144
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000847 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000828 Cytosol/Stoichiometry/1.0
right: Dihydroxyacetone phosphate
right: Glyceraldehyde
spontaneous: false
left: Fructose 1-phosphate
name: Fructose 1-phosphate ↔ Dihydroxyacetone phosphate + Glyceraldehyde
conversion direction: REVERSIBLE

Pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyrophosphate

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/CAS 15978-08-2
type: UnificationXref
id: 15978-08-2
db: CAS

Reference/CAS 488-69-7
type: UnificationXref
id: 488-69-7
db: CAS

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

D-Glyceraldehyde 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GAP
xref: Reference/ChEBI CHEBI 17138
xref: Reference/HMDB HMDB0001112
xref: Reference/ChemSpider 709
xref: Reference/KEGG Compound C00661
xref: Reference/PubChem-compound 729
xref: Reference/CAS 591-59-3
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C000869

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/UniProt Q9M0F9
type: UnificationXref
id: Q9M0F9
db: UniProt

Reference/UniProt Q9MA79
type: UnificationXref
id: Q9MA79
db: UniProt

Reference/ChemSpider 389526
type: UnificationXref
id: 389526
db: ChemSpider

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Compound/PW C001144 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000170 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Compound/PW C000168 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sorbitol
stoichiometric coefficient: 1.0

Reference/CAS 50-70-4
type: UnificationXref
id: 50-70-4
db: CAS

Reference/KEGG Compound C00354
type: UnificationXref
id: C00354
db: KEGG Compound

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/ChEBI CHEBI 28602
type: UnificationXref
id: CHEBI:28602
db: ChEBI

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/ChemSpider 94762
type: UnificationXref
id: 94762
db: ChemSpider

Reference/UniProt C0Z2K3
type: UnificationXref
id: C0Z2K3
db: UniProt

Reference/UniProt Q8W4M5
type: UnificationXref
id: Q8W4M5
db: UniProt

Fructose 1,6-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Fructose 1,6-bisphosphate

D-Fructose
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-535
xref: Reference/ChEBI CHEBI 28645
xref: Reference/ChemSpider 388775
xref: Reference/PubChem-compound 439709
xref: Reference/KEGG Compound C02336
xref: Reference/HMDB HMDB0000660
xref: Reference/CAS 53188-23-1
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000517

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/CAS 79082-92-1
type: UnificationXref
id: 79082-92-1
db: CAS

Reference/SMPDB SMP0000859
type: UnificationXref
id: SMP0000859
db: SMPDB

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Compound/PW C000721 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

fructose-1,6-bisphosphatase (cytosolic)
type: Protein
cellular location: Cytosol
entity reference: fructose-1,6-bisphosphatase (cytosolic)

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

β-D-Fructose 6-phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440641
xref: Reference/ChemSpider 389526
xref: Reference/ChEBI CHEBI 16084
xref: Reference/KEGG Compound C05345
xref: Reference/BioCyc FRUCTOSE-6P
xref: Reference/HMDB HMDB0003971
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C002021

α-D-Glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003345
xref: Reference/ChemSpider 71358
xref: Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
xref: Reference/PubChem-compound 79025
xref: Reference/ChEBI CHEBI 17925
xref: Reference/CAS 492-62-6
xref: Reference/KEGG Compound C00267
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C001851

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Reference/HMDB HMDB0003971
type: UnificationXref
id: HMDB0003971
db: HMDB

Fructose 1-phosphate
type: SmallMoleculeReference
xref: Reference/CAS 15978-08-2
xref: Reference/KEGG Compound C01094
xref: Reference/PubChem-compound 10400369
xref: Reference/ChEBI CHEBI 704854
xref: Reference/ChemSpider 8575807
xref: Reference/BioCyc FRU1P
xref: Reference/HMDB HMDB0001076
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C000847

Reference/ChemSpider 388775
type: UnificationXref
id: 388775
db: ChemSpider

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17924
type: UnificationXref
id: CHEBI:17924
db: ChEBI

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/BioCyc FRUCTOSE-6P
type: UnificationXref
id: FRUCTOSE-6P
db: BioCyc

Compound/PW C000825 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Fructose 2,6-bisphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 105021
type: UnificationXref
id: 105021
db: PubChem-compound

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/PubChem-compound 440641
type: UnificationXref
id: 440641
db: PubChem-compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/UniProt Q9SID0
type: UnificationXref
id: Q9SID0
db: UniProt

Amino Sugar and Nucleotide Sugar Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway4828
pathway component: SubPathwayInteraction4828
name: SubPathway

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/ChEBI CHEBI 17138
type: UnificationXref
id: CHEBI:17138
db: ChEBI

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

SubPathwayInteraction4828
type: Interaction
name: SubPathway4828Reaction
name: SubPathwayReaction
participant: D-Fructose

fructose-bisphosphate aldolase 4
type: Protein
cellular location: Cytosol
entity reference: fructose-bisphosphate aldolase 4

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Galactose Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway4831
pathway component: SubPathwayInteraction4831
name: SubPathway

Reference/KEGG Compound C00267
type: UnificationXref
id: C00267
db: KEGG Compound

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/HMDB HMDB0000247
type: UnificationXref
id: HMDB0000247
db: HMDB

D-Glyceraldehyde 3-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Glyceraldehyde 3-phosphate
name: SubPathwayInput

Reference/ChEBI CHEBI 17925
type: UnificationXref
id: CHEBI:17925
db: ChEBI

Compound/PW C000828 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glyceraldehyde
stoichiometric coefficient: 1.0

Reference/UniProt P48491
type: UnificationXref
id: P48491
db: UniProt

Reference/UniProt Q9MB58
type: UnificationXref
id: Q9MB58
db: UniProt

Reference/PubChem-compound 10400369
type: UnificationXref
id: 10400369
db: PubChem-compound

Reference/KEGG Compound C02336
type: UnificationXref
id: C02336
db: KEGG Compound

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

ChemicalStructure/PW C000847
type: ChemicalStructure
structure format: SMILES

Compound/PW C000517 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Fructose
stoichiometric coefficient: 1.0

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate

Reference/ChEBI CHEBI 28645
type: UnificationXref
id: CHEBI:28645
db: ChEBI

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta 1
type: Protein
cellular location: Cytosol
entity reference: pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta 1

Reference/PubChem-compound 751
type: UnificationXref
id: 751
db: PubChem-compound

Reference/PathWhiz PW013308
type: UnificationXref
id: PW013308
db: PathWhiz

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001112
type: UnificationXref
id: HMDB0001112
db: HMDB

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

D-Fructose
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Fructose
name: SubPathwayInput

ChemicalStructure/PW C000828
type: ChemicalStructure
structure format: SMILES
structure data: OCC(O)C=O

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

xylose isomerase
type: Protein
cellular location: Cytosol
entity reference: xylose isomerase

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

ReactionCatalysis38270
type: Catalysis
controller: triokinase
controlled: 2.7.1.28
control type: ACTIVATION

Arabidopsis thaliana
type: BioSource
xref: Reference/TAXONOMY 3702

ReactionCatalysis38271
type: Catalysis
controller: fructose-bisphosphate aldolase 4
controlled: Reaction48144
control type: ACTIVATION

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

ChemicalStructure/PW C000825
type: ChemicalStructure
structure format: SMILES

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/CAS 591-59-3
type: UnificationXref
id: 591-59-3
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

fructokinase
type: Protein
cellular location: Cytosol
entity reference: fructokinase

Reference/UniProt Q9SYP2
type: UnificationXref
id: Q9SYP2
db: UniProt

Reference/BioCyc FRU1P
type: UnificationXref
id: FRU1P
db: BioCyc

Reference/CAS 492-62-6
type: UnificationXref
id: 492-62-6
db: CAS

Fructose 1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Fructose 1-phosphate

Compound/PW C001851 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 1.0

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Reference/UniProt Q42525
type: UnificationXref
id: Q42525
db: UniProt

ReactionCatalysis38267
type: Catalysis
controller: pyrophosphate--fructose 6-phosphate 1-phosphotransferase
controlled: 2.7.1.90
control type: ACTIVATION

Reference/BioCyc FRUCTOSE-16-DIPHOSPHATE
type: UnificationXref
id: FRUCTOSE-16-DIPHOSPHATE
db: BioCyc

Reference/UniProt Q9FKK7
type: UnificationXref
id: Q9FKK7
db: UniProt

NAD
type: SmallMolecule
cellular location: Cytosol
entity reference: NAD

ReactionCatalysis38266
type: Catalysis
controller: fructose-1,6-bisphosphatase (cytosolic)
controlled: 3.1.3.11
control type: ACTIVATION

ReactionCatalysis38269
type: Catalysis
controller: triosephosphate isomerase (cytosolic)
controlled: 5.3.1.1
control type: ACTIVATION

ReactionCatalysis38268
type: Catalysis
controller: fructose-bisphosphate aldolase 4
controlled: 4.1.2.13
control type: ACTIVATION

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C002021 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Fructose 6-phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Reference/ChEBI CHEBI 16084
type: UnificationXref
id: CHEBI:16084
db: ChEBI

ChemicalStructure/PW C000833
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis38261
type: Catalysis
controller: sorbitol dehydrogenase
controlled: 1.1.1.14
control type: ACTIVATION

Reference/UniProt F4KGQ0
type: UnificationXref
id: F4KGQ0
db: UniProt

ReactionCatalysis38260
type: Catalysis
controller: xylose isomerase
controlled: 5.3.1.5
control type: ACTIVATION

Reference/ChemSpider 5576
type: UnificationXref
id: 5576
db: ChemSpider

Fructose Metabolism
type: Pathway
pathway order: PathwaySubPathway/4830
pathway order: PathwaySubPathway/4831
pathway order: PathwayEnzymeReaction/229148
pathway order: PathwayEnzymeReaction/229149
pathway order: PathwayEnzymeReaction/229158
pathway order: PathwaySubPathway/4828
pathway order: PathwayEnzymeReaction/229155
pathway order: PathwayEnzymeReaction/229156
pathway order: PathwayEnzymeReaction/229153
pathway order: PathwayEnzymeReaction/229154
pathway order: PathwayEnzymeReaction/229151
pathway order: PathwayEnzymeReaction/229162
pathway order: PathwayEnzymeReaction/229152
pathway order: PathwayEnzymeReaction/229150
pathway order: PathwayEnzymeReaction/229161
pathway component: 5.3.1.5
pathway component: 1.1.1.14
pathway component: Reaction48135
pathway component: ReactionCatalysis38270
pathway component: 2.7.1.4
pathway component: 3.1.3.46
pathway component: 2.7.1.11
pathway component: ReactionCatalysis38271
pathway component: 3.1.3.11
pathway component: Amino Sugar and Nucleotide Sugar Metabolism
pathway component: ReactionCatalysis38267
pathway component: ReactionCatalysis38266
pathway component: 2.7.1.90
pathway component: ReactionCatalysis38269
pathway component: 4.1.2.13
pathway component: ReactionCatalysis38268
pathway component: 5.3.1.1
pathway component: 2.7.1.28
pathway component: Glycolysis
pathway component: Reaction48144
pathway component: ReactionCatalysis38261
pathway component: ReactionCatalysis38260
pathway component: ReactionCatalysis38263
pathway component: ReactionCatalysis38262
pathway component: Galactose Metabolism
pathway component: ReactionCatalysis38265
pathway component: ReactionCatalysis38264
xref: Reference/PathWhiz PW013308
xref: Reference/SMPDB SMP0012445
organism: Arabidopsis thaliana

ReactionCatalysis38263
type: Catalysis
controller: fructokinase
controlled: 2.7.1.4
control type: ACTIVATION

ReactionCatalysis38262
type: Catalysis
controller: hexokinase-1
controlled: Reaction48135
control type: ACTIVATION

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

ReactionCatalysis38265
type: Catalysis
controller: 6-phosphofructokinase 1
controlled: 2.7.1.11
control type: ACTIVATION

ReactionCatalysis38264
type: Catalysis
controller: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
controlled: 3.1.3.46
control type: ACTIVATION

Reference/PubChem-compound 445557
type: UnificationXref
id: 445557
db: PubChem-compound

triokinase
type: Protein
cellular location: Cytosol
entity reference: triokinase

Reference/UniProt Q9FJ95
type: UnificationXref
id: Q9FJ95
db: UniProt

α-D-Glucose
type: SmallMolecule
cellular location: Cytosol
entity reference: α-D-Glucose
name: SubPathwayOutput

ChemicalStructure/PW C000168
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

Reference/BioCyc GLYCERALD
type: UnificationXref
id: GLYCERALD
db: BioCyc

Reference/ChemSpider 8575807
type: UnificationXref
id: 8575807
db: ChemSpider

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/ChemSpider 731
type: UnificationXref
id: 731
db: ChemSpider

sorbitol dehydrogenase
type: Protein
cellular location: Cytosol
entity reference: sorbitol dehydrogenase

Reference/PubChem-compound 729
type: UnificationXref
id: 729
db: PubChem-compound

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

triosephosphate isomerase (cytosolic)
type: Protein
cellular location: Cytosol
entity reference: triosephosphate isomerase (cytosolic)

hexokinase-1
type: Protein
cellular location: Cytosol
entity reference: hexokinase-1

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Reference/ChemSpider 71358
type: UnificationXref
id: 71358
db: ChemSpider

Reference/PubChem-compound 79025
type: UnificationXref
id: 79025
db: PubChem-compound

Reference/ChEBI CHEBI 704854
type: UnificationXref
id: CHEBI:704854
db: ChEBI

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Compound/PW C000869 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

Sorbitol
type: SmallMolecule
cellular location: Cytosol
entity reference: Sorbitol

Reference/KEGG Compound C02154
type: UnificationXref
id: C02154
db: KEGG Compound

ChemicalStructure/PW C000869
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C=O

Reference/HMDB HMDB0001047
type: UnificationXref
id: HMDB0001047
db: HMDB

Reference/HMDB HMDB0003345
type: UnificationXref
id: HMDB0003345
db: HMDB

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/ChemSpider 393165
type: UnificationXref
id: 393165
db: ChemSpider

β-D-Fructose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: β-D-Fructose 6-phosphate
name: SubPathwayOutput

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/BioCyc GAP
type: UnificationXref
id: GAP
db: BioCyc

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/PubChem-compound 5780
type: UnificationXref
id: 5780
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/KEGG Compound C00661
type: UnificationXref
id: C00661
db: KEGG Compound

Reference/SMPDB SMP0012445
type: UnificationXref
id: SMP0012445
db: SMPDB

Reference/KEGG Compound C00665
type: UnificationXref
id: C00665
db: KEGG Compound

ChemicalStructure/PW C000517
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

6-phosphofructokinase 1
type: Protein
cellular location: Cytosol
entity reference: 6-phosphofructokinase 1

Glyceraldehyde
type: SmallMolecule
cellular location: Cytosol
entity reference: Glyceraldehyde

Reference/HMDB HMDB0001058
type: UnificationXref
id: HMDB0001058
db: HMDB

ChemicalStructure/PW C002021
type: ChemicalStructure
structure format: SMILES

fructose-bisphosphate aldolase 4
type: ProteinReference
xref: Reference/UniProt F4KGQ0
organism: Arabidopsis thaliana

ChemicalStructure/PW C001851
type: ChemicalStructure
structure format: SMILES

pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta 1
type: ProteinReference
xref: Reference/UniProt Q8W4M5
organism: Arabidopsis thaliana

triokinase
type: ProteinReference
xref: Reference/UniProt C0Z2K3
organism: Arabidopsis thaliana

triosephosphate isomerase (cytosolic)
type: ProteinReference
xref: Reference/UniProt P48491
organism: Arabidopsis thaliana

6-phosphofructokinase 1
type: ProteinReference
xref: Reference/UniProt Q9M0F9
organism: Arabidopsis thaliana

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
type: ProteinReference
xref: Reference/UniProt Q9MB58
organism: Arabidopsis thaliana

pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha 1
type: ProteinReference
xref: Reference/UniProt Q9SYP2
organism: Arabidopsis thaliana

fructose-1,6-bisphosphatase (cytosolic)
type: ProteinReference
xref: Reference/UniProt Q9MA79
organism: Arabidopsis thaliana

Reference/HMDB HMDB0001051
type: UnificationXref
id: HMDB0001051
db: HMDB

fructokinase
type: ProteinReference
xref: Reference/UniProt Q9SID0
organism: Arabidopsis thaliana