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Suppressor of cytokine signaling 7 Suppressor of cytokine signaling 6 Suppressor of cytokine signaling 5 Interleukin-24 Ciliary neurotrophic factor Pro-epidermal growth factor Interleukin-22 receptor subunit alpha-2 Tyrosine- protein kinase JAK1 Tyrosine- protein kinase JAK2 Tyrosine- protein kinase JAK3 Non-receptor tyrosine- protein kinase TYK2 Tyrosine- protein phosphatase non-receptor type 2 Tyrosine- protein phosphatase non-receptor type 6 Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Suppressor of cytokine signaling 4 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 2 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription 6 Tyrosine- protein phosphatase non-receptor type 11 Growth factor receptor-bound protein 2 Phosphatidylinositol- 4,5- bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol- 4,5- bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol- 4,5- bisphosphate 3-kinase catalytic subunit delta isoform Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Cytokine- inducible SH2-containing protein Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 2 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription 6 Son of sevenless homolog 1 Son of sevenless homolog 2 RAC-alpha serine/threonine- protein kinase RAC-beta serine/threonine- protein kinase RAC-gamma serine/threonine- protein kinase Serine/threonine- protein kinase mTOR GTPase HRas RAF proto-oncogene serine/threonine- protein kinase Interferon regulatory factor 9 CREB-binding protein Histone acetyltransferase p300 Tyrosine- protein phosphatase non-receptor type 2 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS2 E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 Four and a half LIM domains protein 1 Apoptosis regulator Bcl-2 Bcl-2-like protein 1 Induced myeloid leukemia cell differentiation protein Mcl-1 Serine/threonine- protein kinase pim-1 Myc proto-oncogene protein G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 Cyclin- dependent kinase inhibitor 1 Aldehyde oxidase Glial fibrillary acidic protein Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 2 Suppressor of cytokine signaling 1 ECS Complex Deoxyribonucleic acid (DNA) Cell cycle Cell survival Proliferation Differentiation Proteasome Anti-apoptosis Cell-cycle progression Cell-cycle inhibition Lipid metabolism Differentiation -p -p +p +p +p STAT dimerization -p +u Cytokine- cytokine receptor interaction Ubiquitin Mediated Proteolysis PI3K-AKT signaling pathway MAPK signaling pathway Apoptosis Cell cycle
SOCS7 SOCS6 SOCS5 IL24 CNTF EGF IL22RA2 JAK1 JAK2 JAK3 TYK2 PTPN2 PTPN6 STAM STAM2 SOCS4 STAT1 STAT2 STAT3 STAT4 STAT5A STAT5B STAT6 PTPN11 GRB2 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 CISH STAT1 STAT2 STAT3 STAT4 STAT5A STAT5B STAT6 SOS1 SOS2 AKT1 AKT2 AKT3 MTOR HRAS RAF1 IRF9 CREBBP EP300 PTPN2 PIAS1 PIAS2 PIAS3 PIAS4 FHL1 BCL2 BCL2L1 MCL1 PIM1 MYC CCND1 CCND2 CCND3 CDKN1A AOX1 GFAP SOCS3 SOCS2 SOCS1 ECS Complex Deoxyribonucleic acid (DNA) Cell cycle Cell survival Proliferation Differentiation Proteasome Anti-apoptosis Cell-cycle progression Cell-cycle inhibition Lipid metabolism Differentiation -p -p +p +p +p STAT dimerization -p +u Cytokine- cytokine receptor interaction Ubiquitin Mediated Proteolysis PI3K-AKT signaling pathway MAPK signaling pathway Apoptosis Cell cycle