Compound/PW C001134 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Protein/14779 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Probable glycerol-3-phosphate dehydrogenase 2
stoichiometric coefficient: 2.0

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

Reference/SMPDB SMP0082506
type: UnificationXref
id: SMP0082506
db: SMPDB

Reaction138236
type: BiochemicalReaction
participant stoichiometry: Compound/Generic156 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic158 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: Phosphate
right: an L-1-phosphatidyl-glycerol
spontaneous: false
left: an L-1-phosphatidylglycerol-phosphate
left: Water
name: Water + an L-1-phosphatidylglycerol-phosphate → Phosphate + an L-1-phosphatidyl-glycerol
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Coenzyme A
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: Coenzyme A

2.7.7.41
type: BiochemicalReaction
participant stoichiometry: Compound/Generic142 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic230 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: Pyrophosphate
right: a CDP-diacylglycerol
spontaneous: false
EC number: 2.7.7.41
left: Cytidine triphosphate
left: 1,2-Diacyl-sn-glycerol 3-phosphate
name: 1,2-Diacyl-sn-glycerol 3-phosphate + Cytidine triphosphate → Pyrophosphate + a CDP-diacylglycerol
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Pyrophosphate
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Pyrophosphate

Reference/UniProt Q19388
type: UnificationXref
id: Q19388
db: UniProt

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Transport6003
type: Transport
participant stoichiometry: Compound/Generic230 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic230 Mitochondrial Outer Membrane/Stoichiometry/1.0
right: 1,2-Diacyl-sn-glycerol 3-phosphate
spontaneous: true
left: 1,2-Diacyl-sn-glycerol 3-phosphate
name: 1,2-Diacyl-sn-glycerol 3-phosphate (→) Transport: Caenorhabditis elegans, Cell, Mitochondrial Outer Membrane to Caenorhabditis elegans, Cell, Mitochondrial Inner Membrane
conversion direction: REVERSIBLE

NADH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADH

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Compound/PW C001104 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Cytidine triphosphate
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Cytidine triphosphate

Compound/PW C000064 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

Phosphate
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Phosphate

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: O4P
molecular weight: 94.95342
structure: ChemicalStructure/PW C001104

Reference/UniProt P53439
type: UnificationXref
id: P53439
db: UniProt

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Compound/Generic156 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: an L-1-phosphatidyl-glycerol
stoichiometric coefficient: 1.0

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Compound/Generic230 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1,2-Diacyl-sn-glycerol 3-phosphate
stoichiometric coefficient: 1.0

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

1,2-Diacyl-sn-glycerol 3-phosphate
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: 1,2-Diacyl-sn-glycerol 3-phosphate

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Reference/UniProt O01916
type: UnificationXref
id: O01916
db: UniProt

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/PathWhiz PW088465
type: UnificationXref
id: PW088465
db: PathWhiz

Compound/PW C001144 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

1-Acyl-sn-glycerol 3-phosphate
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: 1-Acyl-sn-glycerol 3-phosphate

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])([O-])=O

an L-1-phosphatidylglycerol-phosphate
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: an L-1-phosphatidylglycerol-phosphate

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Cytidine monophosphate
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Cytidine monophosphate

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Glycolysis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway75707
pathway component: SubPathwayInteraction75707
xref: Reference/SMPDB SMP0087446
xref: Reference/PathWhiz PW088465
name: SubPathway

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Compound/PW C000721 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ReactionCatalysis128274
type: Catalysis
controller: Probable cardiolipin synthase (CMP-forming)
controlled: Reaction138197
control type: ACTIVATION

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

ReactionCatalysis128272
type: Catalysis
controller: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
controlled: Reaction138195
control type: ACTIVATION

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Probable glycerol-3-phosphate acyltransferase, mitochondrial
type: Protein
cellular location: Mitochondrial Outer Membrane
entity reference: Probable glycerol-3-phosphate acyltransferase, mitochondrial

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

Mitochondrial Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005743

Reference/SMPDB SMP0087446
type: UnificationXref
id: SMP0087446
db: SMPDB

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Reference/UniProt Q93841
type: UnificationXref
id: Q93841
db: UniProt

Compound/PW C001420 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Compound/Generic158 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: an L-1-phosphatidylglycerol-phosphate
stoichiometric coefficient: 1.0

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: O7P2
molecular weight: 173.91193
structure: ChemicalStructure/PW C000170

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/GENE ONTOLOGY GO 0005743
type: UnificationXref
id: GO:0005743
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Reference/GENE ONTOLOGY GO 0005741
type: UnificationXref
id: GO:0005741
db: GENE ONTOLOGY

Compound/PW C000081 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1
type: Protein
cellular location: Mitochondrial Outer Membrane
entity reference: Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1

Water
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Water

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

Compound/PW C000057 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

Reference/UniProt Q22949
type: UnificationXref
id: Q22949
db: UniProt

Mitochondrial Outer Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005741

1-Acyl-sn-glycerol 3-phosphate
type: SmallMoleculeReference

Glycerol 3-phosphate
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: Glycerol 3-phosphate

Compound/PW C000170 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/PathWhiz PW083524
type: UnificationXref
id: PW083524
db: PathWhiz

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

1,2-Diacyl-sn-glycerol 3-phosphate
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: 1,2-Diacyl-sn-glycerol 3-phosphate

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Reaction138197
type: BiochemicalReaction
participant stoichiometry: Compound/Generic141 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic156 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic142 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: Cytidine monophosphate
right: a cardiolipin
spontaneous: false
left: a CDP-diacylglycerol
left: an L-1-phosphatidyl-glycerol
name: a CDP-diacylglycerol + an L-1-phosphatidyl-glycerol → Cytidine monophosphate + a cardiolipin
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

Compound/PW C000081 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: [O-]P([O-])(=O)OP([O-])([O-])=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Compound/Generic230 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1,2-Diacyl-sn-glycerol 3-phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

Reaction138195
type: BiochemicalReaction
participant stoichiometry: Compound/Generic142 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic158 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: Cytidine monophosphate
right: an L-1-phosphatidylglycerol-phosphate
spontaneous: false
left: a CDP-diacylglycerol
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + a CDP-diacylglycerol → Cytidine monophosphate + an L-1-phosphatidylglycerol-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P34517
type: UnificationXref
id: P34517
db: UniProt

Long-chain fatty acyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Outer Membrane
entity reference: Long-chain fatty acyl-CoA

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Caenorhabditis elegans
type: BioSource
xref: Reference/TAXONOMY 6239

Probable glycerol-3-phosphate dehydrogenase 2
type: Protein
cellular location: Cytosol
entity reference: Probable glycerol-3-phosphate dehydrogenase 2

Cardiolipin Biosynthesis
type: Pathway
pathway order: PathwayEnzymeReaction/1561927
pathway order: PathwayEnzymeReaction/1561926
pathway order: PathwayEnzymeReaction/1561918
pathway order: PathwayEnzymeReaction/1561912
pathway order: PathwaySubPathway/75707
pathway order: PathwayEnzymeReaction/1561913
pathway order: PathwayEnzymeReaction/1561921
pathway order: PathwayEnzymeReaction/1562974
pathway order: PathwayTransport/1562101
pathway component: Glycolysis
pathway component: Transport6003
pathway component: ReactionCatalysis128274
pathway component: Reaction138195
pathway component: ReactionCatalysis128272
pathway component: ReactionCatalysis128206
pathway component: Reaction138197
pathway component: 2.3.1.15
pathway component: ReactionCatalysis128203
pathway component: Reaction138236
pathway component: ReactionCatalysis128313
pathway component: ReactionCatalysis128202
pathway component: ReactionCatalysis128312
pathway component: Reaction138125
pathway component: 2.7.7.41
pathway component: 2.3.1.51
xref: Reference/SMPDB SMP0082506
xref: Reference/PathWhiz PW083524
organism: Caenorhabditis elegans

Probable glycerol-3-phosphate dehydrogenase 2
type: ProteinReference
xref: Reference/UniProt P34517
organism: Caenorhabditis elegans

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

Probable cardiolipin synthase (CMP-forming)
type: ProteinReference
xref: Reference/UniProt O01916
organism: Caenorhabditis elegans

Uncharacterized protein
type: ProteinReference
xref: Reference/UniProt Q19388
organism: Caenorhabditis elegans

Reference/TAXONOMY 6239
type: UnificationXref
id: 6239
db: TAXONOMY

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: ProteinReference
xref: Reference/UniProt Q9BL79
organism: Caenorhabditis elegans

Phosphatidate cytidylyltransferase
type: ProteinReference
xref: Reference/UniProt P53439
organism: Caenorhabditis elegans

Compound/Generic142 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: a CDP-diacylglycerol
stoichiometric coefficient: 1.0

an L-1-phosphatidylglycerol-phosphate
type: SmallMoleculeReference

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Reference/UniProt Q9BL79
type: UnificationXref
id: Q9BL79
db: UniProt

Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1
type: ProteinReference
xref: Reference/UniProt Q93841
organism: Caenorhabditis elegans

Probable glycerol-3-phosphate acyltransferase, mitochondrial
type: ProteinReference
xref: Reference/UniProt Q22949
organism: Caenorhabditis elegans

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Compound/Generic141 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: a cardiolipin
stoichiometric coefficient: 1.0

ReactionCatalysis128206
type: Catalysis
controller: Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1
controlled: 2.3.1.51
control type: ACTIVATION

ReactionCatalysis128203
type: Catalysis
controller: Probable glycerol-3-phosphate acyltransferase, mitochondrial
controlled: 2.3.1.15
control type: ACTIVATION

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

ReactionCatalysis128202
type: Catalysis
controller: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
controlled: Reaction138125
control type: ACTIVATION

an L-1-phosphatidyl-glycerol
type: SmallMoleculeReference

NAD
type: SmallMolecule
cellular location: Cytosol
entity reference: NAD

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/Generic210 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Long-chain fatty acyl-CoA
stoichiometric coefficient: 1.0

Phosphatidate cytidylyltransferase
type: Protein
cellular location: Mitochondrial Inner Membrane
entity reference: Phosphatidate cytidylyltransferase

Glycerol 3-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glycerol 3-phosphate

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

a cardiolipin
type: SmallMoleculeReference

a CDP-diacylglycerol
type: SmallMoleculeReference

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

a CDP-diacylglycerol
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: a CDP-diacylglycerol

Probable cardiolipin synthase (CMP-forming)
type: Protein
cellular location: Mitochondrial Inner Membrane
entity reference: Probable cardiolipin synthase (CMP-forming)

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

a cardiolipin
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: a cardiolipin

Glycerol 3-phosphate
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Glycerol 3-phosphate

Long-chain fatty acyl-CoA
type: SmallMoleculeReference

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: Protein
cellular location: Mitochondrial Inner Membrane
entity reference: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Compound/Generic137 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1-Acyl-sn-glycerol 3-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

ReactionCatalysis128313
type: Catalysis
controller: Uncharacterized protein
controlled: Reaction138236
control type: ACTIVATION

ReactionCatalysis128312
type: Catalysis
controller: Phosphatidate cytidylyltransferase
controlled: 2.7.7.41
control type: ACTIVATION

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

an L-1-phosphatidyl-glycerol
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: an L-1-phosphatidyl-glycerol

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

Compound/PW C000081 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
type: Complex
component stoichiometry: Protein/14779 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Probable glycerol-3-phosphate dehydrogenase 2

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

1,2-Diacyl-sn-glycerol 3-phosphate
type: SmallMoleculeReference

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C001099 Mitochondrial Outer Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Uncharacterized protein
type: Protein
cellular location: Mitochondrial Inner Membrane
entity reference: Uncharacterized protein

2.3.1.15
type: BiochemicalReaction
participant stoichiometry: Compound/Generic210 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic137 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Outer Membrane/Stoichiometry/1.0
right: 1-Acyl-sn-glycerol 3-phosphate
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.15
left: Long-chain fatty acyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Long-chain fatty acyl-CoA → 1-Acyl-sn-glycerol 3-phosphate + Coenzyme A
conversion direction: LEFT_TO_RIGHT

Reaction138125
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081 Cytosol/Stoichiometry/1.0
right: NAD
right: Glycerol 3-phosphate
spontaneous: false
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
left: NADH
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADH → Glycerol 3-phosphate + NAD
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

2.3.1.51
type: BiochemicalReaction
participant stoichiometry: Compound/Generic137 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic210 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Mitochondrial Outer Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic230 Mitochondrial Outer Membrane/Stoichiometry/1.0
right: 1,2-Diacyl-sn-glycerol 3-phosphate
right: Coenzyme A
spontaneous: false
EC number: 2.3.1.51
left: Long-chain fatty acyl-CoA
left: 1-Acyl-sn-glycerol 3-phosphate
name: 1-Acyl-sn-glycerol 3-phosphate + Long-chain fatty acyl-CoA → 1,2-Diacyl-sn-glycerol 3-phosphate + Coenzyme A
conversion direction: LEFT_TO_RIGHT

SubPathwayInteraction75707
type: Interaction
name: SubPathwayReaction
name: SubPathway75707Reaction
participant: Dihydroxyacetone phosphate

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O