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Pathway Description
T Helper Cell Surface Molecules
Homo sapiens
Disease Pathway
The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system. They help the activity of other immune cells by releasing T cell cytokines. These cells help suppress or regulate immune responses. They are essential in B cell antibody class switching, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages.
References
T Helper Cell Surface Molecules References
Klocperk A, Parackova Z, Bloomfield M, Rataj M, Pokorny J, Unger S, Warnatz K, Sediva A: Follicular Helper T Cells in DiGeorge Syndrome. Front Immunol. 2018 Jul 23;9:1730. doi: 10.3389/fimmu.2018.01730. eCollection 2018.
Pubmed: 30083170
Lam TS, van de Meent M, Marijt EWA, Falkenburg JHF, Jedema I: Immune surveillance by autoreactive CD4-positive helper T cells is a common phenomenon in patients with acute myeloid leukemia. Eur J Haematol. 2018 Aug 4. doi: 10.1111/ejh.13157.
Pubmed: 30076646
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