Loading Pathway...
Error: Pathway image not found.
Hide
Pathway Description
Chitin Biosynthesis
Drosophila melanogaster
Metabolic Pathway
Chitin is a linear homopolymer of N-acetyl-β-D-glucosamine residues linked by β-1,4 glycosidic bonds to form microfibrils. These become the structural component to cell walls and many extracellular matrices such as cuticles and exoskeleton of insects. This process is highly conserved and occurs in many different organisms including insects and fungi. Chitin exist in several crystaline forms termed α, β and γ chitin, the most abundant being α chitin (reviewed in [Merzendorfer11]). Chitin and lipids are secreted by epidermal cells and form the basis for the cuticle material and layered structure.
References
Chitin Biosynthesis References
Merzendorfer H: The cellular basis of chitin synthesis in fungi and insects: common principles and differences. Eur J Cell Biol. 2011 Sep;90(9):759-69. doi: 10.1016/j.ejcb.2011.04.014. Epub 2011 Jun 22.
Pubmed: 21700357
Arguelles JC: Physiological roles of trehalose in bacteria and yeasts: a comparative analysis. Arch Microbiol. 2000 Oct;174(4):217-24.
Pubmed: 11081789
Elbein AD, Pan YT, Pastuszak I, Carroll D: New insights on trehalose: a multifunctional molecule. Glycobiology. 2003 Apr;13(4):17R-27R. doi: 10.1093/glycob/cwg047. Epub 2003 Jan 22.
Pubmed: 12626396
Moussian B, Schwarz H, Bartoszewski S, Nusslein-Volhard C: Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster. J Morphol. 2005 Apr;264(1):117-30. doi: 10.1002/jmor.10324.
Pubmed: 15747378
Highlighted elements will appear in red.
Highlight Compounds
Highlight Proteins
Enter relative concentration values (without units). Elements will be highlighted in a color gradient where red = lowest concentration and green = highest concentration. For the best results, view the pathway in Black and White.
Visualize Compound Data
Visualize Protein Data
Downloads
Settings