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Amiloride-
sensitive
sodium channel
subunit alpha
Amiloride-
sensitive
sodium channel
subunit beta
Amiloride-
sensitive
sodium channel
subunit alpha
Amiloride-
sensitive
sodium channel
subunit gamma
Sodium/potassium-
transporting
ATPase subunit
alpha-1
Sodium/potassium-
transporting
ATPase subunit
alpha-2
Sodium/potassium-
transporting
ATPase subunit
alpha-2
Sodium/potassium-
transporting
ATPase subunit
alpha-2
Sodium/potassium-
transporting
ATPase subunit
beta-2
Sodium/potassium-
transporting
ATPase subunit
beta-2
Sodium/potassium-
transporting
ATPase subunit
beta-3
Unknown
Sodium/potassium-
transporting
ATPase subunit
gamma
Solute carrier
family 12
member 3
H(+)/Cl(-)
exchange
transporter 7
H(+)/Cl(-)
exchange
transporter 7
Amiloride-
sensitive
sodium channel
subunit alpha
Amiloride-
sensitive
sodium channel
subunit beta
Amiloride-
sensitive
sodium channel
subunit alpha
Amiloride-
sensitive
sodium channel
subunit gamma
Excitatory
amino acid
transporter 3
Solute carrier
family 7 member
10
Solute carrier
family 3
(Activators of
dibasic and
neutral amino
acid
transport),
member 2
Blood-brain
barrier large
neutral amino
acid
transporter
Solute carrier
family 3
(Activators of
dibasic and
neutral amino
acid
transport),
member 2
Sodium-
dependent
neutral amino
acid
transporter
B(0)AT2
Sodium-coupled
neutral amino
acid
transporter 2
SLC7A7 protein
Solute carrier
family 3
(Activators of
dibasic and
neutral amino
acid
transport),
member 2
SLC7A7 protein
Solute carrier
family 3
(Activators of
dibasic and
neutral amino
acid
transport),
member 2
Solute carrier
family 3
(Cystine,
dibasic and
neutral amino
acid
transporters,
activator of
cystine,
dibasic and
neutral amino
acid
transport),
member 1
Solute carrier
family 7
(Cationic amino
acid
transporter, y+
system), member
9
Urea
transporter 1
Urea
transporter 1
Estrogen
receptor
Cl-
Cl-
Na+
Na+
Na+
K+
K+
Cl-
Cl-
H2 O
H2 O
H2 O
Na+
Na+
K+
K+
Cl-
Cl-
Cl-
Cl-
Na+
K+
K+
Cl-
Cl-
K+
K+
H2 O
H2 O
H2 O
H2 O
Na+
Na+
Na+
Na+
K+
K+
Na+
Na+
Na+
Na+
Cl-
Cl-
Na+
Na+
Na+
Na+
Na+
Na+
Urea
Urea
Hydrogen
carbonate
Hydrogen
carbonate
Hydrogen
carbonate
Hydrogen
carbonate
L-Cysteine
L-Cysteine
Urea
Aldosterone
Organic Anion
Organic Anion
Organic Cation
Organic Cation
L-Amino acid
L-Amino acid
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Imino acids
Imino acids
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
Transcription/Translation
PROXIMAL CONVOLUTED TUBULE
LUMEN
INTERSTITIUM
BLADDER
DISTAL CONVOLUTED TUBULE
LUMEN
INTERSTITIUM
DESCENDING LIMB OF LOOP OF
HENLE
LUMEN
INTERSTITIUM
THICK ASCENDING LIMB OF LOOP
OF HENLE
LUMEN
LUMEN
INTERSTITIUM
COLLECTING TUBULE
INTERSTITIUM
Nucleus
SCNN1A
SCNN1B
SCNN1A
SCNN1G
ATP1A1
ATP1A2
ATP1A2
ATP1A2
ATP1B2
ATP1B2
ATP1B3
Unknown
FXYD2
SLC12A3
CLCN7
CLCN7
SCNN1A
SCNN1B
SCNN1A
SCNN1G
SLC1A1
SLC7A10
SLC3A2
SLC7A5
SLC3A2
SLC6A15
SLC38A2
SLC7A7
SLC3A2
SLC7A7
SLC3A2
SLC3A1
SLC7A9
SLC14A1
SLC14A1
ESR1
Chloride ion
Chloride ion
Sodium
Sodium
Sodium
Potassium
Potassium
Chloride ion
Chloride ion
Water
Water
Water
Sodium
Sodium
Potassium
Potassium
Chloride ion
Chloride ion
Chloride ion
Chloride ion
Sodium
Potassium
Potassium
Chloride ion
Chloride ion
Potassium
Potassium
Water
Water
Water
Water
Sodium
Sodium
Sodium
Sodium
Potassium
Potassium
Sodium
Sodium
Sodium
Sodium
Chloride ion
Chloride ion
Sodium
Sodium
Sodium
Sodium
Sodium
Sodium
Urea
Urea
Hydrogen
carbonate
Hydrogen
carbonate
Hydrogen
carbonate
Hydrogen
carbonate
L-Cysteine
L-Cysteine
Urea
Aldosterone
Organic Anion
Organic Anion
Organic Cation
Organic Cation
L-Amino acid
L-Amino acid
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Large Neutral
Amino Acids
Imino acids
Imino acids
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
L-Amino acid
Transcription/Translation
SCNN1A
SCNN1B
SCNN1A
SCNN1G
ATP1A1
ATP1A2
ATP1A2
ATP1A2
ATP1B2
ATP1B2
ATP1B3
FXYD2
SLC12A3
CLCN7
CLCN7
SCNN1A
SCNN1B
SCNN1A
SCNN1G
SLC1A1
SLC7A10
SLC3A2
SLC7A5
SLC3A2
SLC6A15
SLC38A2
SLC7A7
SLC3A2
SLC7A7
SLC3A2
SLC3A1
SLC7A9
SLC14A1
SLC14A1
ESR1
Cl-
Cl-
Na+
Na+
Na+
K+
K+
Cl-
Cl-
H2 O
H2 O
H2 O
Na+
Na+
K+
K+
Cl-
Cl-
Cl-
Cl-
Na+
K+
K+
Cl-
Cl-
K+
K+
H2 O
H2 O
H2 O
H2 O
Na+
Na+
Na+
Na+
K+
K+
Na+
Na+
Na+
Na+
Cl-
Cl-
Na+
Na+
Na+
Na+
Na+
Na+
Urea
Urea
HCO3
HCO3
HCO3
HCO3
Cys
Cys
Urea
Aldostr
OA
OA
OC
OC
LAA
LAA
LNAA
LNAA
LNAA
LNAA
IA
IA
LAA
LAA
LAA
LAA
LAA
LAA
PW000455
PROXIMAL CONVOLUTED TUBULE
LUMEN
INTERSTITIUM
BLADDER
DISTAL CONVOLUTED TUBULE
LUMEN
INTERSTITIUM
DESCENDING LIMB OF LOOP OF
HENLE
LUMEN
INTERSTITIUM
THICK ASCENDING LIMB OF LOOP
OF HENLE
LUMEN
LUMEN
INTERSTITIUM
COLLECTING TUBULE
INTERSTITIUM
Nucleus
SCNN1A
SCNN1B
SCNN1A
SCNN1G
ATP1A1
ATP1A2
ATP1A2
ATP1A2
ATP1B2
ATP1B2
ATP1B3
FXYD2
SLC12A3
CLCN7
CLCN7
SCNN1A
SCNN1B
SCNN1A
SCNN1G
SLC1A1
SLC7A10
SLC3A2
SLC7A5
SLC3A2
SLC6A15
SLC38A2
SLC7A7
SLC3A2
SLC7A7
SLC3A2
SLC3A1
SLC7A9
SLC14A1
SLC14A1
ESR1
Cl
Cl
Na+
Na+
Na+
K+
K+
Cl
Cl
H2O
H2O
H2O
Na+
Na+
K+
K+
Cl
Cl
Cl
Cl
Na+
K+
K+
Cl
Cl
K+
K+
H2O
H2O
H2O
H2O
Na+
Na+
Na+
Na+
K+
K+
Na+
Na+
Na+
Na+
Cl
Cl
Na+
Na+
Na+
Na+
Na+
Na+
Urea
Urea
HCO3
HCO3
HCO3
HCO3
Cys
Cys
Urea
Aldostr
OA
OA
OC
OC
LAA
LAA
LNAA
LNAA
LNAA
LNAA
IA
IA
LAA
LAA
LAA
LAA
LAA
LAA
PW000455