Compound/PW C002665 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 11-cis-Retinol
stoichiometric coefficient: 1.0

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

4-Hydroxyretinoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 4-Hydroxyretinoic acid

Reference/ChemSpider 4451124
type: UnificationXref
id: 4451124
db: ChemSpider

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/KEGG Compound C00670
type: UnificationXref
id: C00670
db: KEGG Compound

Reference/ChemSpider 392618
type: UnificationXref
id: 392618
db: ChemSpider

Unknown
type: ProteinReference
organism: Mus musculus

Unknown
type: ProteinReference
organism: Mus musculus

Unknown
type: ProteinReference
organism: Mus musculus

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ReactionCatalysis100737
type: Catalysis
controller: Alcohol dehydrogenase 1A
controlled: 1.1.1.1
control type: ACTIVATION

Reference/HMDB HMDB0002152
type: UnificationXref
id: HMDB0002152
db: HMDB

TG(16:1(9Z)/22:0/16:1(9Z))
type: SmallMoleculeReference
xref: Reference/ChemSpider 30777879
xref: Reference/HMDB HMDB0048523
chemical formula: C57H106O6
molecular weight: 886.79895
structure: ChemicalStructure/PW C029134

Reference/CAS 66592-72-1
type: UnificationXref
id: 66592-72-1
db: CAS

PC(24:1(15Z)/15:0)
type: SmallMolecule
cellular location: Cytosol
entity reference: PC(24:1(15Z)/15:0)

Reference/CAS 38030-57-8
type: UnificationXref
id: 38030-57-8
db: CAS

5.3.4.1
type: BiochemicalReaction
participant stoichiometry: Compound/Generic40 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001227 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/Generic41 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001786 Cytosol/Stoichiometry/1.0
right: Retinoyl b-glucuronide
right: Acceptor
spontaneous: false
EC number: 5.3.4.1
left: all-trans-Retinoic acid
left: Reduced acceptor
name: Reduced acceptor + all-trans-Retinoic acid → Acceptor + Retinoyl b-glucuronide
conversion direction: LEFT_TO_RIGHT

Retinoyl b-glucuronide
type: SmallMolecule
cellular location: Cytosol
entity reference: Retinoyl b-glucuronide

Reference/ChEBI CHEBI 545914
type: UnificationXref
id: CHEBI:545914
db: ChEBI

ReactionCatalysis100749
type: Catalysis
controller: Unknown
controlled: Reaction110434
control type: ACTIVATION

Reference/CAS 116-31-4
type: UnificationXref
id: 116-31-4
db: CAS

NADH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADH

ChemicalStructure/PW C007859
type: ChemicalStructure
structure format: SMILES
structure data: C\C(=C/CO)\C=C\C=C(/C)\C=C\C1=C(C)C(=O)CCC1(C)C

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/ChEBI CHEBI 15022
type: UnificationXref
id: CHEBI:15022
db: ChEBI

ReactionCatalysis100751
type: Catalysis
controller: Unknown
controlled: 2.3.1.135
control type: ACTIVATION

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

ReactionCatalysis100750
type: Catalysis
controller: Unknown
controlled: 2.3.1.75
control type: ACTIVATION

11-cis-Retinaldehyde
type: SmallMolecule
cellular location: Cytosol
entity reference: 11-cis-Retinaldehyde

1.1.1.300
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002666 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002667 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: 9-cis-Retinal
right: NADPH
spontaneous: false
EC number: 1.1.1.300
left: NADP
left: 9-cis-Retinol
name: 9-cis-Retinol + NADP → 9-cis-Retinal + NADPH
conversion direction: LEFT_TO_RIGHT

All-trans-13,14-dihydroretinol
type: SmallMoleculeReference
xref: Reference/CAS 115797-14-3
xref: Reference/KEGG Compound C15492
xref: Reference/HMDB HMDB0011618
xref: Reference/BioCyc CPD-7247
xref: Reference/PubChem-compound 446798
xref: Reference/ChEBI CHEBI 52075
xref: Reference/ChemSpider 394057
chemical formula: C20H32O
molecular weight: 288.24533
structure: ChemicalStructure/PW C007207

1.2.1.36
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002667 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001600 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
right: 9-cis-Retinoic acid
right: NADH
spontaneous: false
EC number: 1.2.1.36
left: NAD
left: 9-cis-Retinal
left: Water
name: 9-cis-Retinal + NAD + Water → 9-cis-Retinoic acid + NADH
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis100759
type: Catalysis
controller: Unknown
controlled: 1.2.1.36
control type: ACTIVATION

Reference/HMDB HMDB0003141
type: UnificationXref
id: HMDB0003141
db: HMDB

ReactionCatalysis100758
type: Catalysis
controller: Retinal dehydrogenase 1
controlled: 1.2.1.36
control type: ACTIVATION

1.2.1.36
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002667 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001600 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
right: 9-cis-Retinoic acid
right: NADH
spontaneous: false
EC number: 1.2.1.36
left: NAD
left: 9-cis-Retinal
left: Water
name: 9-cis-Retinal + NAD + Water → 9-cis-Retinoic acid + NADH
conversion direction: LEFT_TO_RIGHT

1.1.1.300
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002666 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002667 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: 9-cis-Retinal
right: NADPH
spontaneous: false
EC number: 1.1.1.300
left: NADP
left: 9-cis-Retinol
name: 9-cis-Retinol + NADP ↔ 9-cis-Retinal + NADPH
conversion direction: REVERSIBLE

ReactionCatalysis100757
type: Catalysis
controller: Unknown
controlled: 1.1.1.184
control type: ACTIVATION

ReactionCatalysis100756
type: Catalysis
controller: Unknown
controlled: 1.1.1.300
control type: ACTIVATION

1.1.1.184
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002666 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002667 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: 9-cis-Retinal
right: NADPH
spontaneous: false
EC number: 1.1.1.184
left: NADP
left: 9-cis-Retinol
name: 9-cis-Retinol + NADP ↔ 9-cis-Retinal + NADPH
conversion direction: REVERSIBLE

ReactionCatalysis100755
type: Catalysis
controller: Unknown
controlled: 1.1.1.300
control type: ACTIVATION

1.14.-.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007859 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
right: 4-Oxoretinol
spontaneous: false
EC number: 1.14.-.-
left: Vitamin A
name: Vitamin A → 4-Oxoretinol
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis100754
type: Catalysis
controller: Unknown
controlled: 1.14.99.36
control type: ACTIVATION

1.3.99.23
type: BiochemicalReaction
participant stoichiometry: Compound/Generic40 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/Generic41 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007207 Cytosol/Stoichiometry/1.0
right: All-trans-13,14-dihydroretinol
right: Acceptor
spontaneous: false
EC number: 1.3.99.23
left: Vitamin A
left: Reduced acceptor
name: Reduced acceptor + Vitamin A → Acceptor + All-trans-13,14-dihydroretinol
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis100753
type: Catalysis
controller: Unknown
controlled: 3.1.1.3
control type: ACTIVATION

1.2.1.36
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001227 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
right: all-trans-Retinoic acid
right: NADH
spontaneous: false
EC number: 1.2.1.36
left: NAD
left: Vitamin A
left: Water
name: NAD + Vitamin A + Water → NADH + all-trans-Retinoic acid
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis100752
type: Catalysis
controller: Unknown
controlled: 1.1.1.300
control type: ACTIVATION

1.2.1.36
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001227 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
right: all-trans-Retinoic acid
right: NADH
spontaneous: false
EC number: 1.2.1.36
left: NAD
left: Vitamin A
left: Water
name: NAD + Vitamin A + Water → NADH + all-trans-Retinoic acid
conversion direction: LEFT_TO_RIGHT

Compound/PW C001448 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 11-cis-Retinaldehyde
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17336
type: UnificationXref
id: CHEBI:17336
db: ChEBI

Reference/ChEBI CHEBI 17579
type: UnificationXref
id: CHEBI:17579
db: ChEBI

Protein/7725 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

ReactionCatalysis100739
type: Catalysis
controller: Unknown
controlled: 1.1.1.184
control type: ACTIVATION

ReactionCatalysis100738
type: Catalysis
controller: Unknown
controlled: 1.1.1.-
control type: ACTIVATION

Reference/ChemSpider 64931
type: UnificationXref
id: 64931
db: ChemSpider

Reference/PubChem-compound 6436082
type: UnificationXref
id: 6436082
db: PubChem-compound

ReactionCatalysis100740
type: Catalysis
controller: Unknown
controlled: 1.1.-.-
control type: ACTIVATION

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

1.14.-.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002690 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001227 Cytosol/Stoichiometry/1.0
right: 4-Hydroxyretinoic acid
spontaneous: false
EC number: 1.14.-.-
left: all-trans-Retinoic acid
name: all-trans-Retinoic acid → 4-Hydroxyretinoic acid
conversion direction: LEFT_TO_RIGHT

1.14.-.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002690 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002706 Cytosol/Stoichiometry/1.0
right: 4-oxo-Retinoic acid
spontaneous: false
EC number: 1.14.-.-
left: 4-Hydroxyretinoic acid
name: 4-Hydroxyretinoic acid → 4-oxo-Retinoic acid
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis100748
type: Catalysis
controller: Unknown
controlled: 3.1.1.64
control type: ACTIVATION

ReactionCatalysis100747
type: Catalysis
controller: Unknown
controlled: Reaction110432
control type: ACTIVATION

TG(16:1(9Z)/22:0/16:1(9Z))
type: SmallMolecule
cellular location: Cytosol
entity reference: TG(16:1(9Z)/22:0/16:1(9Z))

ReactionCatalysis100746
type: Catalysis
controller: Unknown
controlled: 2.3.1.75
control type: ACTIVATION

1.14.-.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007979 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001227 Cytosol/Stoichiometry/1.0
right: all-trans-18-Hydroxyretinoic acid
spontaneous: false
EC number: 1.14.-.-
left: all-trans-Retinoic acid
name: all-trans-Retinoic acid → all-trans-18-Hydroxyretinoic acid
conversion direction: LEFT_TO_RIGHT

Mus musculus
type: BioSource
xref: Reference/TAXONOMY 10090

ReactionCatalysis100745
type: Catalysis
controller: Unknown
controlled: 2.3.1.135
control type: ACTIVATION

1.14.13.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001227 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007978 Cytosol/Stoichiometry/1.0
right: all-trans-5,6-Epoxyretinoic acid
spontaneous: false
EC number: 1.14.13.-
left: all-trans-Retinoic acid
name: all-trans-Retinoic acid → all-trans-5,6-Epoxyretinoic acid
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis100744
type: Catalysis
controller: Unknown
controlled: 1.1.1.300
control type: ACTIVATION

Reference/CAS 22737-96-8
type: UnificationXref
id: 22737-96-8
db: CAS

ReactionCatalysis100743
type: Catalysis
controller: Unknown
controlled: 1.1.-.-
control type: ACTIVATION

Reference/CAS 28319-77-9
type: UnificationXref
id: 28319-77-9
db: CAS

ReactionCatalysis100742
type: Catalysis
controller: Unknown
controlled: 1.1.1.300
control type: ACTIVATION

Compound/PW C001948 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Retinyl palmitate
stoichiometric coefficient: 1.0

ReactionCatalysis100741
type: Catalysis
controller: Unknown
controlled: 1.1.1.300
control type: ACTIVATION

1.1.1.300
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001448 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002665 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: 11-cis-Retinol
right: NADPH
spontaneous: false
EC number: 1.1.1.300
left: 11-cis-Retinaldehyde
left: NADP
name: 11-cis-Retinaldehyde + NADP → 11-cis-Retinol + NADPH
conversion direction: LEFT_TO_RIGHT

Compound/Generic61/Stoichiometry/1.0
type: Stoichiometry
physical entity: iodopsin
stoichiometric coefficient: 1.0

1.1.1.300
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001448 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001048 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: Retinal
right: NADPH
spontaneous: false
EC number: 1.1.1.300
left: 11-cis-Retinaldehyde
left: NADP
name: 11-cis-Retinaldehyde + NADP → NADPH + Retinal
conversion direction: LEFT_TO_RIGHT

1.1.-.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001448 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001048 Cytosol/Stoichiometry/1.0
right: Retinal
spontaneous: false
EC number: 1.1.-.-
left: 11-cis-Retinaldehyde
name: 11-cis-Retinaldehyde → Retinal
conversion direction: LEFT_TO_RIGHT

Compound/PW C000146 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00473
type: UnificationXref
id: C00473
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/PubChem-compound 444795
type: UnificationXref
id: 444795
db: PubChem-compound

Compound/PW C001144 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/BioCyc PHOSPHATIDYLCHOLINE
type: UnificationXref
id: PHOSPHATIDYLCHOLINE
db: BioCyc

Compound/PW C002666 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 9-cis-Retinol
stoichiometric coefficient: 1.0

ChemicalStructure/PW C007207
type: ChemicalStructure
structure format: SMILES
structure data: CC(CCO)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C

1.1.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001448 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001048 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
right: Retinal
right: NADH
spontaneous: false
EC number: 1.1.1.1
left: NAD
left: 11-cis-Retinaldehyde
name: 11-cis-Retinaldehyde + NAD → NADH + Retinal
conversion direction: LEFT_TO_RIGHT

1.1.-.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001448 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001048 Cytosol/Stoichiometry/1.0
right: Retinal
spontaneous: false
EC number: 1.1.-.-
left: 11-cis-Retinaldehyde
name: 11-cis-Retinaldehyde → Retinal
conversion direction: LEFT_TO_RIGHT

1.1.1.300
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001448 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001048 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: Retinal
right: NADPH
spontaneous: false
EC number: 1.1.1.300
left: 11-cis-Retinaldehyde
left: NADP
name: 11-cis-Retinaldehyde + NADP → NADPH + Retinal
conversion direction: LEFT_TO_RIGHT

1.1.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001448 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001048 Cytosol/Stoichiometry/1.0
right: Retinal
spontaneous: false
EC number: 1.1.1.-
left: 11-cis-Retinaldehyde
name: 11-cis-Retinaldehyde → Retinal
conversion direction: LEFT_TO_RIGHT

1.1.1.184
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001448 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001048 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: Retinal
right: NADPH
spontaneous: false
EC number: 1.1.1.184
left: 11-cis-Retinaldehyde
left: NADP
name: 11-cis-Retinaldehyde + NADP → NADPH + Retinal
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 63795
type: UnificationXref
id: CHEBI:63795
db: ChEBI

3.1.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C029134 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001935 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003195 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
right: Vitamin A
right: TG(16:1(9Z)/22:0/16:1(9Z))
spontaneous: false
EC number: 3.1.1.3
left: DG(16:1(9Z)/22:0/0:0)
left: Retinyl ester
name: DG(16:1(9Z)/22:0/0:0) + Retinyl ester → TG(16:1(9Z)/22:0/16:1(9Z)) + Vitamin A
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

1.14.99.36
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000437 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001048 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065 Cytosol/Stoichiometry/1.0
right: Retinal
spontaneous: false
EC number: 1.14.99.36
left: Oxygen
left: B-Carotene
name: B-Carotene + Oxygen → Retinal
conversion direction: LEFT_TO_RIGHT

9-cis-Retinal
type: SmallMolecule
cellular location: Cytosol
entity reference: 9-cis-Retinal

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

9-cis-Retinoic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0002369
xref: Reference/ChEBI CHEBI 50648
xref: Reference/KEGG Compound C15493
xref: Reference/ChemSpider 395778
xref: Reference/CAS 5300-03-8
xref: Reference/PubChem-compound 449171
chemical formula: C20H28O2
molecular weight: 300.20892
structure: ChemicalStructure/PW C001600

Reference/BioCyc Beta-D-Glucuronides
type: UnificationXref
id: Beta-D-Glucuronides
db: BioCyc

Acceptor
type: SmallMolecule
cellular location: Cytosol
entity reference: Acceptor

Reference/ChEBI CHEBI 16066
type: UnificationXref
id: CHEBI:16066
db: ChEBI

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

NADPH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADPH

Protein/7782 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Compound/PW C002706 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-oxo-Retinoic acid
stoichiometric coefficient: 1.0

Reaction110432
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002665 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001948 Cytosol/Stoichiometry/1.0
right: Coenzyme A
right: Retinyl palmitate
spontaneous: false
left: 11-cis-Retinol
left: Acetyl-CoA
name: 11-cis-Retinol + Acetyl-CoA → Coenzyme A + Retinyl palmitate
conversion direction: LEFT_TO_RIGHT

3.1.1.64
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002665 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001935 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/Generic25 Cytosol/Stoichiometry/1.0
right: 11-cis-Retinol
right: Fatty Acid
spontaneous: false
EC number: 3.1.1.64
left: Retinyl ester
left: Water
name: Retinyl ester + Water → 11-cis-Retinol + Fatty Acid
conversion direction: LEFT_TO_RIGHT

2.3.1.135
type: BiochemicalReaction
participant stoichiometry: Compound/PW C004838 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002665 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001948 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000059 Cytosol/Stoichiometry/1.0
right: Glycerophosphocholine
right: Retinyl palmitate
spontaneous: false
EC number: 2.3.1.135
left: PC(24:1(15Z)/15:0)
left: 11-cis-Retinol
name: 11-cis-Retinol + PC(24:1(15Z)/15:0) → Glycerophosphocholine + Retinyl palmitate
conversion direction: LEFT_TO_RIGHT

2.3.1.75
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002665 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001948 Cytosol/Stoichiometry/1.0
right: Coenzyme A
right: Retinyl palmitate
spontaneous: false
EC number: 2.3.1.75
left: 11-cis-Retinol
left: Acetyl-CoA
name: 11-cis-Retinol + Acetyl-CoA → Coenzyme A + Retinyl palmitate
conversion direction: LEFT_TO_RIGHT

2.3.1.135
type: BiochemicalReaction
participant stoichiometry: Compound/PW C004838 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001935 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000059 Cytosol/Stoichiometry/1.0
right: Glycerophosphocholine
right: Retinyl ester
spontaneous: false
EC number: 2.3.1.135
left: Vitamin A
left: PC(24:1(15Z)/15:0)
name: PC(24:1(15Z)/15:0) + Vitamin A → Glycerophosphocholine + Retinyl ester
conversion direction: LEFT_TO_RIGHT

Reference/CAS 62702-55-0
type: UnificationXref
id: 62702-55-0
db: CAS

1.1.1.300
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001048 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
right: Retinal
right: NADPH
spontaneous: false
EC number: 1.1.1.300
left: Vitamin A
left: NADP
name: NADP + Vitamin A → NADPH + Retinal
conversion direction: LEFT_TO_RIGHT

Compound/PW C001600 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 9-cis-Retinoic acid
stoichiometric coefficient: 1.0

Reaction110434
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001935 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
right: Coenzyme A
right: Retinyl ester
spontaneous: false
left: Vitamin A
left: Acetyl-CoA
name: Acetyl-CoA + Vitamin A → Coenzyme A + Retinyl ester
conversion direction: LEFT_TO_RIGHT

2.3.1.75
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001935 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
right: Coenzyme A
right: Retinyl ester
spontaneous: false
EC number: 2.3.1.75
left: Vitamin A
left: Acetyl-CoA
name: Acetyl-CoA + Vitamin A → Coenzyme A + Retinyl ester
conversion direction: LEFT_TO_RIGHT

Reference/CAS 302-79-4
type: UnificationXref
id: 302-79-4
db: CAS

Compound/PW C029134 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: TG(16:1(9Z)/22:0/16:1(9Z))
stoichiometric coefficient: 1.0

Compound/Generic40 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Reduced acceptor
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMolecule
cellular location: Cytosol
entity reference: Coenzyme A

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Retinyl ester
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-437
xref: Reference/HMDB HMDB0003598
xref: Reference/KEGG Compound C02075
xref: Reference/ChEBI CHEBI 545914
xref: Reference/PubChem-compound 5460164
xref: Reference/ChemSpider 10607936
chemical formula: C20H30O2
molecular weight: 302.22458
structure: ChemicalStructure/PW C001935

Reference/KEGG Compound C00376
type: UnificationXref
id: C00376
db: KEGG Compound

Reference/PathWhiz PW121754
type: UnificationXref
id: PW121754
db: PathWhiz

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/HMDB HMDB0006216
type: UnificationXref
id: HMDB0006216
db: HMDB

Reference/HMDB HMDB0006217
type: UnificationXref
id: HMDB0006217
db: HMDB

Reference/HMDB HMDB0006218
type: UnificationXref
id: HMDB0006218
db: HMDB

Compound/Generic41 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acceptor
stoichiometric coefficient: 1.0

Reference/ChemSpider 7822721
type: UnificationXref
id: 7822721
db: ChemSpider

Retinyl palmitate
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-523
xref: Reference/HMDB HMDB0003648
xref: Reference/PubChem-compound 5280531
xref: Reference/ChEBI CHEBI 17616
xref: Reference/KEGG Compound C02588
xref: Reference/CAS 79-81-2
xref: Reference/ChemSpider 4444162
chemical formula: C36H60O2
molecular weight: 524.45935
structure: ChemicalStructure/PW C001948

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

ChemicalStructure/PW C003195
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@](CO)(COC(=O)CCCCCCC\C=C/CCCCCC)OC(=O)CCCCCCCCCCCCCCCCCCCCC

NADP
type: SmallMolecule
cellular location: Cytosol
entity reference: NADP

Compound/Generic25 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fatty Acid
stoichiometric coefficient: 1.0

Reference/BioCyc DIACYLGLYCEROL
type: UnificationXref
id: DIACYLGLYCEROL
db: BioCyc

Reference/ChEBI CHEBI 52075
type: UnificationXref
id: CHEBI:52075
db: ChEBI

Reference/KEGG Compound C00157
type: UnificationXref
id: C00157
db: KEGG Compound

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Compound/PW C000437 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: B-Carotene
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0003648
type: UnificationXref
id: HMDB0003648
db: HMDB

ChemicalStructure/PW C000059
type: ChemicalStructure
structure format: SMILES
structure data: C[N+](C)(C)CCOP([O-])(=O)OC[C@@H](O)CO

Compound/PW C001227 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: all-trans-Retinoic acid
stoichiometric coefficient: 1.0

B-Carotene
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17579
xref: Reference/PubChem-compound 5280489
xref: Reference/BioCyc CPD1F-129
xref: Reference/KEGG Compound C02094
xref: Reference/ChemSpider 4444129
xref: Reference/CAS 7235-40-7
xref: Reference/HMDB HMDB0000561
chemical formula: C40H56
molecular weight: 536.4382
structure: ChemicalStructure/PW C000437

Retinal
type: SmallMolecule
cellular location: Cytosol
entity reference: Retinal

Compound/PW C001048 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Retinal
stoichiometric coefficient: 1.0

Protein/7725 Cytosol/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

Reference/KEGG Compound C11061
type: UnificationXref
id: C11061
db: KEGG Compound

Compound/PW C002667 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 9-cis-Retinal
stoichiometric coefficient: 1.0

Reference/KEGG Compound C02588
type: UnificationXref
id: C02588
db: KEGG Compound

Reference/KEGG Compound C00165
type: UnificationXref
id: C00165
db: KEGG Compound

Reference/HMDB HMDB0001358
type: UnificationXref
id: HMDB0001358
db: HMDB

11-cis-Retinol
type: SmallMolecule
cellular location: Cytosol
entity reference: 11-cis-Retinol

Glycerophosphocholine
type: SmallMolecule
cellular location: Cytosol
entity reference: Glycerophosphocholine

Reference/CAS 514-85-2
type: UnificationXref
id: 514-85-2
db: CAS

Reference/KEGG Compound C02110
type: UnificationXref
id: C02110
db: KEGG Compound

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

4-oxo-Retinoic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6437063
xref: Reference/KEGG Compound C16678
xref: Reference/ChemSpider 4941652
xref: Reference/HMDB HMDB0006285
xref: Reference/CAS 38030-57-8
xref: Reference/ChEBI CHEBI 269971
chemical formula: C20H26O3
molecular weight: 314.1882
structure: ChemicalStructure/PW C002706

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

ChemicalStructure/PW C002690
type: ChemicalStructure
structure format: SMILES
structure data: C\C(\C=C\C1=C(C)C(O)CCC1(C)C)=C/C=C/C(/C)=C/C(O)=O

Reference/ChemSpider 394057
type: UnificationXref
id: 394057
db: ChemSpider

NAD
type: SmallMolecule
cellular location: Cytosol
entity reference: NAD

Reference/ChemSpider 4445170
type: UnificationXref
id: 4445170
db: ChemSpider

Fatty Acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Fatty Acid

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

all-trans-18-Hydroxyretinoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: all-trans-18-Hydroxyretinoic acid

Compound/PW C001786 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Retinoyl b-glucuronide
stoichiometric coefficient: 1.0

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/CAS 79-81-2
type: UnificationXref
id: 79-81-2
db: CAS

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

Compound/Generic60/Stoichiometry/1.0
type: Stoichiometry
physical entity: Bathorodopsin
stoichiometric coefficient: 1.0

Compound/Generic59/Stoichiometry/1.0
type: Stoichiometry
physical entity: Rhodopsin
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Protein/7725 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

11-cis-Retinaldehyde
type: SmallMoleculeReference
xref: Reference/CAS 564-87-4
xref: Reference/HMDB HMDB0002152
xref: Reference/BioCyc CPD-881
xref: Reference/KEGG Compound C02110
xref: Reference/ChEBI CHEBI 16066
xref: Reference/ChemSpider 4444130
xref: Reference/PubChem-compound 5280490
chemical formula: C20H28O
molecular weight: 284.21402
structure: ChemicalStructure/PW C001448

Compound/PW C003195 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: DG(16:1(9Z)/22:0/0:0)
stoichiometric coefficient: 1.0

PC(24:1(15Z)/15:0)
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0008790
xref: Reference/ChemSpider 24767449
xref: Reference/PubChem-compound 53479491
xref: Reference/KEGG Compound C00157
xref: Reference/BioCyc PHOSPHATIDYLCHOLINE
chemical formula: C47H92NO8P
molecular weight: 829.65607
structure: ChemicalStructure/PW C004838

Reference/ChEBI CHEBI 269971
type: UnificationXref
id: CHEBI:269971
db: ChEBI

ReactionCatalysis100762
type: Catalysis
controller: Unknown
controlled: 1.14.-.-
control type: ACTIVATION

ChemicalStructure/PW C007978
type: ChemicalStructure
structure format: SMILES
structure data: C\C(\C=C\C12OC1(C)CCCC2(C)C)=C/C=C/C(/C)=C/C(O)=O

Reference/HMDB HMDB0002369
type: UnificationXref
id: HMDB0002369
db: HMDB

ReactionCatalysis100761
type: Catalysis
controller: Unknown
controlled: 1.2.1.36
control type: ACTIVATION

ChemicalStructure/PW C007979
type: ChemicalStructure
structure format: SMILES
structure data: C\C(\C=C\C1=C(CO)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O

ReactionCatalysis100760
type: Catalysis
controller: Retinal dehydrogenase 1
controlled: 1.2.1.36
control type: ACTIVATION

Reference/PubChem-compound 5289090
type: UnificationXref
id: 5289090
db: PubChem-compound

11-cis-Retinol
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00899
xref: Reference/ChEBI CHEBI 16302
xref: Reference/HMDB HMDB0006216
xref: Reference/BioCyc CPD-882
xref: Reference/PubChem-compound 5280382
xref: Reference/CAS 22737-96-8
xref: Reference/ChemSpider 4444073
chemical formula: C20H30O
molecular weight: 286.22968
structure: ChemicalStructure/PW C002665

Reference/CAS 22737-97-9
type: UnificationXref
id: 22737-97-9
db: CAS

ReactionCatalysis100768
type: Catalysis
controller: Cytochrome P450
controlled: 1.14.13.-
control type: ACTIVATION

ReactionCatalysis100767
type: Catalysis
controller: Unknown
controlled: 1.14.-.-
control type: ACTIVATION

ReactionCatalysis100766
type: Catalysis
controller: Unknown
controlled: 1.14.-.-
control type: ACTIVATION

ReactionCatalysis100765
type: Catalysis
controller: Unknown
controlled: 1.14.-.-
control type: ACTIVATION

ReactionCatalysis100764
type: Catalysis
controller: UDP-glucuronosyltransferase 1-1
controlled: 5.3.4.1
control type: ACTIVATION

ReactionCatalysis100763
type: Catalysis
controller: Unknown
controlled: 1.3.99.23
control type: ACTIVATION

Vitamin A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17336
xref: Reference/HMDB HMDB0000305
xref: Reference/KEGG Compound C00473
xref: Reference/BioCyc RETINOL
xref: Reference/PubChem-compound 445354
xref: Reference/CAS 68-26-8
xref: Reference/ChemSpider 393012
chemical formula: C20H30O
molecular weight: 286.22968
structure: ChemicalStructure/PW C000209

Reference/KEGG Compound C16681
type: UnificationXref
id: C16681
db: KEGG Compound

Reference/KEGG Compound C16682
type: UnificationXref
id: C16682
db: KEGG Compound

Retinal dehydrogenase 1
type: Complex
component stoichiometry: Protein/7725 Cytosol/Stoichiometry/4.0
cellular location: Cytosol
component: Unknown

Reference/KEGG Compound C16683
type: UnificationXref
id: C16683
db: KEGG Compound

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/KEGG Compound C16680
type: UnificationXref
id: C16680
db: KEGG Compound

11-cis-Retinaldehyde
type: SmallMolecule
entity reference: 11-cis-Retinaldehyde

Reference/PubChem-compound 446798
type: UnificationXref
id: 446798
db: PubChem-compound

Compound/PW C000209 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Vitamin A
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5363137
type: UnificationXref
id: 5363137
db: PubChem-compound

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

ChemicalStructure/PW C001048
type: ChemicalStructure
structure format: SMILES
structure data: C\C(\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C/C=O

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/ChEBI CHEBI 6796
type: UnificationXref
id: CHEBI:6796
db: ChEBI

Reference/KEGG Compound C16678
type: UnificationXref
id: C16678
db: KEGG Compound

Reference/ChemSpider 4941652
type: UnificationXref
id: 4941652
db: ChemSpider

Reference/KEGG Compound C16679
type: UnificationXref
id: C16679
db: KEGG Compound

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/PubChem-compound 6438629
type: UnificationXref
id: 6438629
db: PubChem-compound

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/KEGG Compound C16677
type: UnificationXref
id: C16677
db: KEGG Compound

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

Compound/PW C007979 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: all-trans-18-Hydroxyretinoic acid
stoichiometric coefficient: 1.0

Retinoyl b-glucuronide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5281877
xref: Reference/KEGG Compound C11061
xref: Reference/CAS 401-10-5
xref: Reference/HMDB HMDB0003141
xref: Reference/BioCyc Beta-D-Glucuronides
xref: Reference/ChEBI CHEBI 28870
xref: Reference/ChemSpider 4445170
chemical formula: C26H36O8
molecular weight: 476.24103
structure: ChemicalStructure/PW C001786

Reference/PubChem-compound 445354
type: UnificationXref
id: 445354
db: PubChem-compound

Reference/HMDB HMDB0003598
type: UnificationXref
id: HMDB0003598
db: HMDB

Reference/ChEBI CHEBI 6562
type: UnificationXref
id: CHEBI:6562
db: ChEBI

Reference/PubChem-compound 6506224
type: UnificationXref
id: 6506224
db: PubChem-compound

Reference/BioCyc RETINOL
type: UnificationXref
id: RETINOL
db: BioCyc

Reference/HMDB HMDB0000086
type: UnificationXref
id: HMDB0000086
db: HMDB

Reference/ChemSpider 8123435
type: UnificationXref
id: 8123435
db: ChemSpider

9-cis-Retinol
type: SmallMolecule
cellular location: Cytosol
entity reference: 9-cis-Retinol

Reference/KEGG Compound C15492
type: UnificationXref
id: C15492
db: KEGG Compound

UDP-glucuronosyltransferase 1-1
type: Complex
component stoichiometry: Protein/7736 Cytosol/Stoichiometry/1.0
component stoichiometry: Protein/7780 Cytosol/Stoichiometry/1.0
component stoichiometry: Protein/7781 Cytosol/Stoichiometry/1.0
component stoichiometry: Protein/7782 Cytosol/Stoichiometry/1.0
cellular location: Cytosol
component: Unknown

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/ChemSpider 24767449
type: UnificationXref
id: 24767449
db: ChemSpider

Reference/KEGG Compound C15493
type: UnificationXref
id: C15493
db: KEGG Compound

ChemicalStructure/PW C000209
type: ChemicalStructure
structure format: SMILES
structure data: C\C(=C/CO)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C

Reference/CAS 564-87-4
type: UnificationXref
id: 564-87-4
db: CAS

Reference/PubChem-compound 5280489
type: UnificationXref
id: 5280489
db: PubChem-compound

ChemicalStructure/PW C001786
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Acetyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Acetyl-CoA

4-Hydroxyretinoic acid
type: SmallMoleculeReference
xref: Reference/CAS 66592-72-1
xref: Reference/PubChem-compound 6438629
xref: Reference/ChemSpider 4943093
xref: Reference/HMDB HMDB0006254
xref: Reference/KEGG Compound C16677
xref: Reference/ChEBI CHEBI 63795
chemical formula: C20H28O3
molecular weight: 316.20386
structure: ChemicalStructure/PW C002690

Reference/CAS 115797-14-3
type: UnificationXref
id: 115797-14-3
db: CAS

Compound/PW C001065 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 1.0

Compound/PW C000143 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/KEGG Compound C02075
type: UnificationXref
id: C02075
db: KEGG Compound

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

all-trans-5,6-Epoxyretinoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: all-trans-5,6-Epoxyretinoic acid

Reference/HMDB HMDB0000305
type: UnificationXref
id: HMDB0000305
db: HMDB

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

DG(16:1(9Z)/22:0/0:0)
type: SmallMolecule
cellular location: Cytosol
entity reference: DG(16:1(9Z)/22:0/0:0)

Reference/TAXONOMY 10090
type: UnificationXref
id: 10090
db: TAXONOMY

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reaction1716
type: BiochemicalReaction
participant stoichiometry: Compound/Generic63/Stoichiometry/1.0
participant stoichiometry: Compound/Generic62/Stoichiometry/1.0
right: Metarodopsin
spontaneous: false
left: Lumirodopsin
name: Lumirodopsin → Metarodopsin
conversion direction: LEFT_TO_RIGHT

Reaction1717
type: BiochemicalReaction
participant stoichiometry: Compound/Generic63/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001048/Stoichiometry/1.0
right: Retinal
spontaneous: false
left: Metarodopsin
name: Metarodopsin → Retinal
conversion direction: LEFT_TO_RIGHT

Reaction1714
type: BiochemicalReaction
participant stoichiometry: Compound/Generic61/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001448/Stoichiometry/1.0
right: 11-cis-Retinaldehyde
spontaneous: false
left: iodopsin
name: iodopsin → 11-cis-Retinaldehyde
conversion direction: LEFT_TO_RIGHT

Reaction1715
type: BiochemicalReaction
participant stoichiometry: Compound/Generic60/Stoichiometry/1.0
participant stoichiometry: Compound/Generic62/Stoichiometry/1.0
right: Lumirodopsin
spontaneous: false
left: Bathorodopsin
name: Bathorodopsin → Lumirodopsin
conversion direction: LEFT_TO_RIGHT

9-cis-Retinol
type: SmallMoleculeReference
xref: Reference/KEGG Compound C16682
xref: Reference/HMDB HMDB0006217
xref: Reference/PubChem-compound 9947823
xref: Reference/ChEBI CHEBI 78272
xref: Reference/CAS 22737-97-9
xref: Reference/ChemSpider 8123435
chemical formula: C20H30O
molecular weight: 286.22968
structure: ChemicalStructure/PW C002666

9-cis-Retinal
type: SmallMoleculeReference
xref: Reference/KEGG Compound C16681
xref: Reference/ChemSpider 4940758
xref: Reference/CAS 514-85-2
xref: Reference/HMDB HMDB0006218
xref: Reference/ChEBI CHEBI 78273
xref: Reference/PubChem-compound 6436082
chemical formula: C20H28O
molecular weight: 284.21402
structure: ChemicalStructure/PW C002667

Reference/PubChem-compound 5280382
type: UnificationXref
id: 5280382
db: PubChem-compound

Rhodopsin
type: SmallMolecule
entity reference: Rhodopsin

Reference/ChemSpider 4444130
type: UnificationXref
id: 4444130
db: ChemSpider

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Vitamin A
type: SmallMolecule
cellular location: Cytosol
entity reference: Vitamin A

Reaction1712
type: BiochemicalReaction
participant stoichiometry: Compound/Generic60/Stoichiometry/1.0
participant stoichiometry: Compound/Generic59/Stoichiometry/1.0
right: Bathorodopsin
spontaneous: false
left: Rhodopsin
name: Rhodopsin → Bathorodopsin
conversion direction: LEFT_TO_RIGHT

Reaction1713
type: BiochemicalReaction
participant stoichiometry: Compound/Generic61/Stoichiometry/1.0
participant stoichiometry: Compound/Generic59/Stoichiometry/1.0
right: iodopsin
spontaneous: false
left: Rhodopsin
name: Rhodopsin → iodopsin
conversion direction: LEFT_TO_RIGHT

Reaction1711
type: BiochemicalReaction
participant stoichiometry: Compound/Generic59/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001448/Stoichiometry/1.0
right: Rhodopsin
spontaneous: false
left: 11-cis-Retinaldehyde
name: 11-cis-Retinaldehyde → Rhodopsin
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/ChemSpider 4940758
type: UnificationXref
id: 4940758
db: ChemSpider

Metarodopsin
type: SmallMolecule
entity reference: Metarodopsin

Reference/BioCyc CPD-523
type: UnificationXref
id: CPD-523
db: BioCyc

iodopsin
type: SmallMolecule
entity reference: iodopsin

Lumirodopsin
type: SmallMolecule
entity reference: Lumirodopsin

Reference/BioCyc CPD-882
type: UnificationXref
id: CPD-882
db: BioCyc

Retinyl palmitate
type: SmallMolecule
cellular location: Cytosol
entity reference: Retinyl palmitate

Reaction1703
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001227 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001600 Cytosol/Stoichiometry/1.0
right: 9-cis-Retinoic acid
spontaneous: false
left: all-trans-Retinoic acid
name: all-trans-Retinoic acid → 9-cis-Retinoic acid
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000437
type: ChemicalStructure
structure format: SMILES
structure data: C\C(\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)CCCC1(C)C

Reference/BioCyc CPD-881
type: UnificationXref
id: CPD-881
db: BioCyc

Reference/PubChem-compound 71920
type: UnificationXref
id: 71920
db: PubChem-compound

all-trans-Retinoic acid
type: SmallMoleculeReference
xref: Reference/CAS 302-79-4
xref: Reference/HMDB HMDB0001852
xref: Reference/KEGG Compound C00777
xref: Reference/ChEBI CHEBI 15367
xref: Reference/PubChem-compound 444795
xref: Reference/ChemSpider 392618
chemical formula: C20H28O2
molecular weight: 300.20892
structure: ChemicalStructure/PW C001227

Reference/PubChem-compound 5280490
type: UnificationXref
id: 5280490
db: PubChem-compound

Reference/KEGG Compound C02094
type: UnificationXref
id: C02094
db: KEGG Compound

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Reference/ChemSpider 4444129
type: UnificationXref
id: 4444129
db: ChemSpider

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H29N7O17P3
molecular weight: 744.08325
structure: ChemicalStructure/PW C000143

Reference/ChemSpider 393012
type: UnificationXref
id: 393012
db: ChemSpider

Reference/ChemSpider 4515523
type: UnificationXref
id: 4515523
db: ChemSpider

Bathorodopsin
type: SmallMolecule
entity reference: Bathorodopsin

Reference/HMDB HMDB0000561
type: UnificationXref
id: HMDB0000561
db: HMDB

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Compound/PW C002690 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-Hydroxyretinoic acid
stoichiometric coefficient: 1.0

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

ChemicalStructure/PW C002667
type: ChemicalStructure
structure format: SMILES
structure data: C\C(\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C\C=O

Reference/ChemSpider 4444073
type: UnificationXref
id: 4444073
db: ChemSpider

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Reference/PubChem-compound 53479491
type: UnificationXref
id: 53479491
db: PubChem-compound

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Retinal
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17898
xref: Reference/HMDB HMDB0001358
xref: Reference/BioCyc CPD-881
xref: Reference/CAS 116-31-4
xref: Reference/PubChem-compound 638015
xref: Reference/ChemSpider 553582
xref: Reference/KEGG Compound C00376
chemical formula: C20H28O
molecular weight: 284.21402
structure: ChemicalStructure/PW C001048

Reference/PubChem-compound 5460164
type: UnificationXref
id: 5460164
db: PubChem-compound

Compound/PW C000940 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 395778
type: UnificationXref
id: 395778
db: ChemSpider

Protein/7736 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Compound/PW C000721 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001227
type: ChemicalStructure
structure format: SMILES
structure data: C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O

Reference/ChEBI CHEBI 35366
type: UnificationXref
id: CHEBI:35366
db: ChEBI

Reference/ChemSpider 10607936
type: UnificationXref
id: 10607936
db: ChemSpider

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/CAS 401-10-5
type: UnificationXref
id: 401-10-5
db: CAS

Reference/HMDB HMDB0048523
type: UnificationXref
id: HMDB0048523
db: HMDB

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Reference/BioCyc CPD-437
type: UnificationXref
id: CPD-437
db: BioCyc

4-oxo-Retinoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 4-oxo-Retinoic acid

Vitamin A Deficiency
type: Pathway
pathway order: PathwayEnzymeReaction/2111798
pathway order: PathwayEnzymeReaction/2111831
pathway order: PathwayEnzymeReaction/2111797
pathway order: PathwayEnzymeReaction/2111830
pathway order: PathwayEnzymeReaction/2111811
pathway order: PathwayEnzymeReaction/2111833
pathway order: PathwayEnzymeReaction/2111799
pathway order: PathwayEnzymeReaction/2111810
pathway order: PathwayEnzymeReaction/2111832
pathway order: PathwayEnzymeReaction/2111813
pathway order: PathwayEnzymeReaction/2111835
pathway order: PathwayEnzymeReaction/2111812
pathway order: PathwayEnzymeReaction/2111834
pathway order: PathwayEnzymeReaction/2111815
pathway order: PathwayEnzymeReaction/2111837
pathway order: PathwayEnzymeReaction/2111814
pathway order: PathwayEnzymeReaction/2111836
pathway order: PathwayEnzymeReaction/2111806
pathway order: PathwayEnzymeReaction/2111828
pathway order: PathwayEnzymeReaction/2111805
pathway order: PathwayEnzymeReaction/2111827
pathway order: PathwayEnzymeReaction/2111808
pathway order: PathwayEnzymeReaction/2111807
pathway order: PathwayEnzymeReaction/2111829
pathway order: PathwayEnzymeReaction/2111809
pathway order: PathwayEnzymeReaction/2111820
pathway order: PathwayEnzymeReaction/2111800
pathway order: PathwayEnzymeReaction/2111822
pathway order: PathwayEnzymeReaction/2111821
pathway order: PathwayEnzymeReaction/2111802
pathway order: PathwayEnzymeReaction/2111824
pathway order: PathwayEnzymeReaction/2111801
pathway order: PathwayEnzymeReaction/2111823
pathway order: PathwayEnzymeReaction/2111804
pathway order: PathwayEnzymeReaction/2111826
pathway order: PathwayEnzymeReaction/2111803
pathway order: PathwayEnzymeReaction/2111825
pathway order: PathwayEnzymeReaction/2111817
pathway order: PathwayEnzymeReaction/2111816
pathway order: PathwayEnzymeReaction/2111819
pathway order: PathwayEnzymeReaction/2111818
pathway component: 1.1.1.300
pathway component: 1.1.-.-
pathway component: Reaction1693
pathway component: ReactionCatalysis100737
pathway component: 1.1.1.1
pathway component: 1.1.1.-
pathway component: 1.1.1.184
pathway component: 3.1.1.3
pathway component: 1.14.99.36
pathway component: ReactionCatalysis100762
pathway component: ReactionCatalysis100761
pathway component: ReactionCatalysis100760
pathway component: Reaction110432
pathway component: 3.1.1.64
pathway component: 2.3.1.135
pathway component: ReactionCatalysis100768
pathway component: 2.3.1.75
pathway component: ReactionCatalysis100767
pathway component: ReactionCatalysis100766
pathway component: ReactionCatalysis100765
pathway component: Reaction110434
pathway component: ReactionCatalysis100764
pathway component: ReactionCatalysis100763
pathway component: 5.3.4.1
pathway component: Reaction1716
pathway component: Reaction1717
pathway component: Reaction1714
pathway component: ReactionCatalysis100749
pathway component: Reaction1715
pathway component: ReactionCatalysis100751
pathway component: ReactionCatalysis100750

Protein/7780 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Cytochrome P450
type: Complex
component stoichiometry: Protein/7725 Cytosol/Stoichiometry/1.0
cellular location: Cytosol
component: Unknown

Retinal
type: SmallMolecule
entity reference: Retinal

Reference/ChemSpider 5005673
type: UnificationXref
id: 5005673
db: ChemSpider

Reference/HMDB HMDB0012451
type: UnificationXref
id: HMDB0012451
db: HMDB

Reference/HMDB HMDB0012452
type: UnificationXref
id: HMDB0012452
db: HMDB

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

9-cis-Retinoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 9-cis-Retinoic acid

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/HMDB HMDB0012329
type: UnificationXref
id: HMDB0012329
db: HMDB

Compound/PW C000059 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerophosphocholine
stoichiometric coefficient: 1.0

4-Oxoretinol
type: SmallMolecule
cellular location: Cytosol
entity reference: 4-Oxoretinol

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Reference/BioCyc GLYCERYLPHOSPHORYLCHOLINE
type: UnificationXref
id: GLYCERYLPHOSPHORYLCHOLINE
db: BioCyc

Glycerophosphocholine
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCERYLPHOSPHORYLCHOLINE
xref: Reference/ChemSpider 64931
xref: Reference/PubChem-compound 71920
xref: Reference/KEGG Compound C00670
xref: Reference/HMDB HMDB0000086
xref: Reference/CAS 28319-77-9
xref: Reference/ChEBI CHEBI 16870
chemical formula: C8H20NO6P
molecular weight: 257.1028
structure: ChemicalStructure/PW C000059

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

ChemicalStructure/PW C001448
type: ChemicalStructure
structure format: SMILES
structure data: C/C(/C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C)=C\C=O

ChemicalStructure/PW C004838
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 9543771
type: UnificationXref
id: 9543771
db: PubChem-compound

Reference/ChemSpider 4444162
type: UnificationXref
id: 4444162
db: ChemSpider

ChemicalStructure/PW C002665
type: ChemicalStructure
structure format: SMILES
structure data: [H]\C(CO)=C(\C)/C(/[H])=C(/[H])C([H])=C(C)C(\[H])=C(/[H])C1=C(C)CCCC1(C)C

ChemicalStructure/PW C002666
type: ChemicalStructure
structure format: SMILES
structure data: C\C(=C\CO)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C

Reference/ChEBI CHEBI 78273
type: UnificationXref
id: CHEBI:78273
db: ChEBI

Reference/ChEBI CHEBI 78272
type: UnificationXref
id: CHEBI:78272
db: ChEBI

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

4-Oxoretinol
type: SmallMoleculeReference
xref: Reference/KEGG Compound C16683
xref: Reference/PubChem-compound 5289090
xref: Reference/HMDB HMDB0012329
xref: Reference/ChemSpider 4451124
xref: Reference/CAS 62702-55-0
chemical formula: C20H28O2
molecular weight: 300.20892
structure: ChemicalStructure/PW C007859

all-trans-18-Hydroxyretinoic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C16679
xref: Reference/PubChem-compound 6506224
xref: Reference/ChemSpider 5005673
xref: Reference/HMDB HMDB0012452
chemical formula: C20H28O3
molecular weight: 316.20386
structure: ChemicalStructure/PW C007979

Metarodopsin
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 6796

Lumirodopsin
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 6562

ChemicalStructure/PW C001935
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Compound/PW C004838 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: PC(24:1(15Z)/15:0)
stoichiometric coefficient: 1.0

Reference/PubChem-compound 9947823
type: UnificationXref
id: 9947823
db: PubChem-compound

Compound/PW C001935 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Retinyl ester
stoichiometric coefficient: 1.0

B-Carotene
type: SmallMolecule
cellular location: Cytosol
entity reference: B-Carotene

Reference/ChEBI CHEBI 16302
type: UnificationXref
id: CHEBI:16302
db: ChEBI

Rhodopsin
type: SmallMoleculeReference
xref: Reference/UniProt P08100

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/ChEBI CHEBI 15339
type: UnificationXref
id: CHEBI:15339
db: ChEBI

Compound/PW C001048/Stoichiometry/1.0
type: Stoichiometry
physical entity: Retinal
stoichiometric coefficient: 1.0

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

ChemicalStructure/PW C001948
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Reference/ChemSpider 4943093
type: UnificationXref
id: 4943093
db: ChemSpider

iodopsin
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 5949

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Bathorodopsin
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 2998

Protein/7781 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 28870
type: UnificationXref
id: CHEBI:28870
db: ChEBI

Reference/HMDB HMDB0008790
type: UnificationXref
id: HMDB0008790
db: HMDB

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Acceptor
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15339

Reduced acceptor
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15022

Reference/ChEBI CHEBI 16870
type: UnificationXref
id: CHEBI:16870
db: ChEBI

Reference/PubChem-compound 5281877
type: UnificationXref
id: 5281877
db: PubChem-compound

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

Reference/PubChem-compound 638015
type: UnificationXref
id: 638015
db: PubChem-compound

ChemicalStructure/PW C029134
type: ChemicalStructure
structure format: SMILES
structure data: [H]C(COC(=O)CCCCCCC\C=C/CCCCCC)(COC(=O)CCCCCCC\C=C/CCCCCC)OC(=O)CCCCCCCCCCCCCCCCCCCCC

Reference/ChEBI CHEBI 5949
type: UnificationXref
id: CHEBI:5949
db: ChEBI

Reference/HMDB HMDB0006254
type: UnificationXref
id: HMDB0006254
db: HMDB

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Reference/ChEBI CHEBI 17616
type: UnificationXref
id: CHEBI:17616
db: ChEBI

Unknown
type: ProteinReference
organism: Mus musculus

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Compound/Generic62/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lumirodopsin
stoichiometric coefficient: 1.0

All-trans-13,14-dihydroretinol
type: SmallMolecule
cellular location: Cytosol
entity reference: All-trans-13,14-dihydroretinol

all-trans-5,6-Epoxyretinoic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 545933
xref: Reference/KEGG Compound C16680
xref: Reference/ChemSpider 4515523
xref: Reference/HMDB HMDB0012451
xref: Reference/PubChem-compound 5363137
chemical formula: C20H28O3
molecular weight: 316.20386
structure: ChemicalStructure/PW C007978

Reference/PubChem-compound 5280531
type: UnificationXref
id: 5280531
db: PubChem-compound

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Alcohol dehydrogenase 1A
type: Complex
component stoichiometry: Protein/7725 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Unknown

Reference/ChEBI CHEBI 15367
type: UnificationXref
id: CHEBI:15367
db: ChEBI

Reference/ChEBI CHEBI 545933
type: UnificationXref
id: CHEBI:545933
db: ChEBI

Reference/BioCyc CPD1F-129
type: UnificationXref
id: CPD1F-129
db: BioCyc

Reference/ChEBI CHEBI 50648
type: UnificationXref
id: CHEBI:50648
db: ChEBI

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Unknown
type: ProteinReference
organism: Mus musculus

Fatty Acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 35366

ChemicalStructure/PW C002706
type: ChemicalStructure
structure format: SMILES
structure data: C\C(\C=C\C1=C(C)C(=O)CCC1(C)C)=C/C=C/C(/C)=C/C(O)=O

Reference/ChemSpider 553582
type: UnificationXref
id: 553582
db: ChemSpider

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001448/Stoichiometry/1.0
type: Stoichiometry
physical entity: 11-cis-Retinaldehyde
stoichiometric coefficient: 1.0

Reaction1693
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002666 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000209 Cytosol/Stoichiometry/1.0
right: 9-cis-Retinol
spontaneous: false
left: Vitamin A
name: Vitamin A → 9-cis-Retinol
conversion direction: LEFT_TO_RIGHT

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Reference/HMDB HMDB0011618
type: UnificationXref
id: HMDB0011618
db: HMDB

Reference/SMPDB SMP0120500
type: UnificationXref
id: SMP0120500
db: SMPDB

Reference/PubChem-compound 449171
type: UnificationXref
id: 449171
db: PubChem-compound

Retinyl ester
type: SmallMolecule
cellular location: Cytosol
entity reference: Retinyl ester

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

Reference/ChemSpider 30777879
type: UnificationXref
id: 30777879
db: ChemSpider

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Compound/PW C007859 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-Oxoretinol
stoichiometric coefficient: 1.0

Oxygen
type: SmallMolecule
cellular location: Cytosol
entity reference: Oxygen

Reference/PubChem-compound 6437063
type: UnificationXref
id: 6437063
db: PubChem-compound

Reference/CAS 5300-03-8
type: UnificationXref
id: 5300-03-8
db: CAS

Compound/PW C007207 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: All-trans-13,14-dihydroretinol
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0006285
type: UnificationXref
id: HMDB0006285
db: HMDB

DG(16:1(9Z)/22:0/0:0)
type: SmallMoleculeReference
xref: Reference/BioCyc DIACYLGLYCEROL
xref: Reference/KEGG Compound C00165
xref: Reference/ChemSpider 7822721
xref: Reference/PubChem-compound 9543771
xref: Reference/HMDB HMDB0007144
chemical formula: C41H78O5
molecular weight: 650.5849
structure: ChemicalStructure/PW C003195

Reference/KEGG Compound C00899
type: UnificationXref
id: C00899
db: KEGG Compound

Reference/KEGG Compound C00777
type: UnificationXref
id: C00777
db: KEGG Compound

Compound/PW C001099 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Compound/Generic63/Stoichiometry/1.0
type: Stoichiometry
physical entity: Metarodopsin
stoichiometric coefficient: 1.0

Compound/PW C007978 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: all-trans-5,6-Epoxyretinoic acid
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0007144
type: UnificationXref
id: HMDB0007144
db: HMDB

Reference/CAS 7235-40-7
type: UnificationXref
id: 7235-40-7
db: CAS

Reference/ChEBI CHEBI 2998
type: UnificationXref
id: CHEBI:2998
db: ChEBI

Reference/ChEBI CHEBI 17898
type: UnificationXref
id: CHEBI:17898
db: ChEBI

Reference/BioCyc CPD-7247
type: UnificationXref
id: CPD-7247
db: BioCyc

Reduced acceptor
type: SmallMolecule
cellular location: Cytosol
entity reference: Reduced acceptor

ChemicalStructure/PW C001600
type: ChemicalStructure
structure format: SMILES

Reference/UniProt P08100
type: UnificationXref
id: P08100
db: UniProt

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Reference/HMDB HMDB0001852
type: UnificationXref
id: HMDB0001852
db: HMDB

all-trans-Retinoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: all-trans-Retinoic acid

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/CAS 68-26-8
type: UnificationXref
id: 68-26-8
db: CAS