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Solute carrier
family 2,
facilitated
glucose
transporter
member 2
Solute carrier
family 2,
facilitated
glucose
transporter
member 2
Mitochondrial
2-
oxoglutarate/malate
carrier protein
Mitochondrial
pyruvate
carrier 1
Mitochondrial
pyruvate
carrier 1
Glucose-6-
phosphatase
Glucose-6-
phosphatase
Phosphoglucomutase-
1
Glucose-6-
phosphate
isomerase
Hexokinase-2
Aldose
1-epimerase
Hexokinase-2
Glucose-6-
phosphate
isomerase
Fructose-1,6-
bisphosphatase
1
Fructose-
bisphosphate
aldolase A
Triosephosphate
isomerase
Glyceraldehyde-
3-phosphate
dehydrogenase
Pantothenate
kinase 1
Phosphoglycerate
mutase 2
Alpha-enolase
Bisphosphoglycerate
mutase
Bisphosphoglycerate
mutase
Phosphoglycerate
mutase 1
Phosphoenolpyruvate
carboxykinase,
cytosolic [GTP]
Malate
dehydrogenase,
mitochondrial
Malate
dehydrogenase,
mitochondrial
Pyruvate
carboxylase,
mitochondrial
Phosphoenolpyruvate
carboxykinase,
cytosolic [GTP]
L-lactate
dehydrogenase A
chain
Pyruvate
carboxylase,
mitochondrial
D-Glucose
Glucose
1-phosphate
D-Glyceraldehyde 3-phosphate
Fructose 6-phosphate
Phosphoenolpyruvic acid
Pyruvic acid
L-Lactic acid
3-Phosphoglyceric acid
Pyruvic acid
D-Glucose
D-Glucose
Pi
Pi
Glucose
6-phosphate
Glucose
6-phosphate
Oxoglutaric
acid
Oxoglutaric
acid
Malic acid
Malic acid
Phosphoenolpyruvic
acid
Pyruvic acid
Pyruvic acid
H2 O
H2 O
Pi
α-D-Glucose
ATP
ADP
β-D-Glucose
ATP
ADP
β-D-Glucose 6-phosphate
Fructose 1,6-bisphosphate
H2 O
Pi
Accumulation
Dihydroxyacetone phosphate
NAD
Pi
Glyceric acid 1,3-biphosphate
NADH
ATP
ADP
2-Phospho-D-glyceric acid
H2 O
2,3-Diphosphoglyceric acid
H2 O
Pi
H2 O
Pi
GTP
Oxalacetic acid
GDP
CO2
NAD
NADH
H+
NAD
Oxalacetic acid
NADH
H+
ATP
Hydrogen
carbonate
ADP
Pi
GTP
Oxalacetic acid
GDP
CO2
NAD
NADH
H+
ATP
Hydrogen
carbonate
ADP
Pi
Magnesium
Magnesium
Magnesium
Manganese
Biotin
Manganese
Manganese
Biotin
Manganese
Galactose
Metabolism
Nucleotide
Sugars
Metabolism
Starch and
Sucrose
Metabolism
Pentose
Phosphate
Pathway
Fructose and
Mannose
Degradation
Galactose
Metabolism
Thiamine
Metabolism
Phenylalanine
and Tyrosine
Metabolism
Pyruvate
Metabolism
Pantothenate
and CoA
Biosynthesis
Aspartate
Metabolism
Tyrosine
Metabolism
Propanoate
Metabolism
Glycerolipid
Metabolism
Alanine
Metabolism
Pyruvate
Metabolism
Capillary Bed
Mitochondra
Endoplasmic Reticulum
Intracellular Space
Extracellular Space
Endoplasmic Reticulum
Mitochondria
Slc2a2
Slc2a2
Slc25a11
Mpc1
Mpc1
G6pc
G6pc
Pgm1
Gpi
Hk2
Galm
Hk2
Gpi
Fbp1
Aldoa
Tpi1
Gapdh
Pank1
Pgam2
Eno1
Bpgm
Bpgm
Pgam1
Pck1
Mdh2
Mdh2
Pc
Pck1
Ldha
Pc
D-Glucose
Glucose
1-phosphate
D-
Glyceraldehyde
3-phosphate
Fructose
6-phosphate
Phosphoenolpyruvic
acid
Pyruvic acid
L-Lactic acid
3-
Phosphoglyceric
acid
Pyruvic acid
D-Glucose
D-Glucose
Phosphate
Phosphate
Glucose
6-phosphate
Glucose
6-phosphate
Oxoglutaric
acid
Oxoglutaric
acid
Malic acid
Malic acid
Phosphoenolpyruvic
acid
Pyruvic acid
Pyruvic acid
Water
Water
Phosphate
α-D-Glucose
Adenosine
triphosphate
Adenosine
diphosphate
β-D-Glucose
Adenosine
triphosphate
Adenosine
diphosphate
β-D-Glucose
6-phosphate
Fructose 1,6-
bisphosphate
Water
Phosphate
Accumulation
Dihydroxyacetone
phosphate
NAD
Phosphoric acid
Glyceric acid
1,3-biphosphate
NADH
Adenosine
triphosphate
Adenosine
diphosphate
2-Phospho-D-
glyceric acid
Water
2,3-
Diphosphoglyceric
acid
Water
Phosphate
Water
Phosphate
Guanosine
triphosphate
Oxalacetic acid
Guanosine
diphosphate
Carbon dioxide
NAD
NADH
Hydrogen Ion
NAD
Oxalacetic acid
NADH
Hydrogen Ion
Adenosine
triphosphate
Hydrogen
carbonate
Adenosine
diphosphate
Phosphate
Guanosine
triphosphate
Oxalacetic acid
Guanosine
diphosphate
Carbon dioxide
NAD
NADH
Hydrogen Ion
Adenosine
triphosphate
Hydrogen
carbonate
Adenosine
diphosphate
Phosphate
Galactose
Metabolism
Nucleotide
Sugars
Metabolism
Starch and
Sucrose
Metabolism
Pentose
Phosphate
Pathway
Fructose and
Mannose
Degradation
Galactose
Metabolism
Thiamine
Metabolism
Phenylalanine
and Tyrosine
Metabolism
Pyruvate
Metabolism
Pantothenate
and CoA
Biosynthesis
Aspartate
Metabolism
Tyrosine
Metabolism
Propanoate
Metabolism
Glycerolipid
Metabolism
Alanine
Metabolism
Pyruvate
Metabolism
Slc2a2
Slc2a2
Slc25a11
Mpc1
Mpc1
G6pc
G6pc
Pgm1
Gpi
Hk2
Galm
Hk2
Gpi
Fbp1
Aldoa
Tpi1
Gapdh
Pank1
Pgam2
Eno1
Bpgm
Bpgm
Pgam1
Pck1
Mdh2
Mdh2
Pc
Pck1
Ldha
Pc
D-Glc
Gluc1P
Glyc3P
Fru6P
Pep
Pyr
Lactate
G3P
Pyr
D-Glc
D-Glc
Pi
Pi
Gluc-6P
Gluc-6P
AKG
AKG
Malate
Malate
Pep
Pyr
Pyr
H2 O
H2 O
Pi
a-D-Glc
ATP
ADP
Glu
ATP
ADP
BDGlu6P
Fru1,6P
H2 O
Pi
Accumulation
Dhapp
NAD
Pi
GlyABp
NADH
ATP
ADP
2PDG
H2 O
23-DpGA
H2 O
Pi
H2 O
Pi
GTP
Oaa
GDP
CO2
NAD
NADH
H+
NAD
Oaa
NADH
H+
ATP
HCO3
ADP
Pi
GTP
Oaa
GDP
CO2
NAD
NADH
H+
ATP
HCO3
ADP
Pi
Mg2+
Mg2+
Mg2+
Mn2+
Biotin
Mn2+
Mn2+
Biotin
Mn2+
PW000159
PW000031
PW000150
PW000055
PW000025
PW000159
PW000036
PW000042
PW000054
PW000032
PW000002
PW000142
PW000149
PW000144
PW000001
PW000054
Capillary Bed
Mitochondra
Endoplasmic Reticulum
Intracellular Space
Extracellular Space
Endoplasmic Reticulum
Mitochondria
Slc2a2
Slc2a2
Slc25a11
Mpc1
Mpc1
G6pc
G6pc
Pgm1
Gpi
Hk2
Galm
Hk2
Gpi
Fbp1
Aldoa
Tpi1
Gapdh
Pank1
Pgam2
Eno1
Bpgm
Bpgm
Pgam1
Pck1
Mdh2
Mdh2
Pc
Pck1
Ldha
Pc
D-Glc
Gluc1P
Glyc3P
Fru6P
Pep
Pyr
Lactate
G3P
Pyr
D-Glc
D-Glc
Pi
Pi
Gluc-6P
Gluc-6P
AKG
AKG
Malate
Malate
Pep
Pyr
Pyr
H2O
H2O
Pi
a-D-Glc
ATP
ADP
Glu
ATP
ADP
BDGlu6P
Fru1,6P
H2O
Pi
Accumulation
Dhapp
NAD
PhosfrA
GlyABp
NADH
ATP
ADP
2PDG
H2O
23-DpGA
H2O
Pi
H2O
Pi
GTP
Oaa
GDP
CO2
NAD
NADH
H+
NAD
Oaa
NADH
H+
ATP
HCO3
ADP
Pi
GTP
Oaa
GDP
CO2
NAD
NADH
H+
ATP
HCO3
ADP
Pi
PW000159
PW000031
PW000150
PW000055
PW000025
PW000159
PW000036
PW000042
PW000054
PW000032
PW000002
PW000142
PW000149
PW000144
PW000001
PW000054