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dGTP Amidophosphoribosyltransferase Phosphoribosylamine- -glycine ligase Phosphoribosylglycinamide formyltransferase 2 Phosphoribosylformylglycinamidine synthase Phosphoribosylformylglycinamidine cyclo-ligase Phosphoribosylaminoimidazole carboxylase ATPase subunit Phosphoribosylaminoimidazole carboxylase catalytic subunit Phosphoribosylaminoimidazole- succinocarboxamide synthase Adenylosuccinate lyase Bifunctional purine biosynthesis protein purH Bifunctional purine biosynthesis protein purH Inosine-5'- monophosphate dehydrogenase Adenylosuccinate synthetase Adenylosuccinate lyase Adenylate kinase GMP synthase [glutamine- hydrolyzing] Guanylate kinase Nucleoside diphosphate kinase Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase 1 subunit beta Nucleoside diphosphate kinase Ribonucleoside- diphosphate reductase 2 subunit beta ATP synthase subunit c ATP synthase subunit b ATP synthase subunit a ATP synthase epsilon chain ATP synthase subunit delta ATP synthase subunit alpha ATP synthase gamma chain ATP synthase subunit beta Anaerobic ribonucleoside- triphosphate reductase Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase 1 subunit beta Ribonucleoside- diphosphate reductase 2 subunit alpha Ribonucleoside- diphosphate reductase 2 subunit beta Nucleoside diphosphate kinase Phosphoribosyl pyrophosphate H2O L-Glutamine 5- Phosphoribosylamine L-Glutamic acid PPi Glycine ATP N1-(5-phospho- β-D- ribosyl)glycinamide Pi ADP H+ ATP Formic acid 5'- Phosphoribosyl- N- formylglycinamide ADP Pi H+ H2O L-Glutamine ATP 2-(Formamido)- N1-(5-phospho- D- ribosyl)acetamidine L-Glutamic acid Pi ADP H+ ATP 5-Aminoimidazole ribonucleotide Pi ADP H+ HCO3- ATP N5- Carboxyaminoimidazole ribonucleotide ADP Pi H+ 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid ATP SAICAR Pi ADP H+ AICAR Fumaric acid FAICAR Inosinic acid H2O NAD H2O NADH H+ Xanthylic acid L-Aspartic acid GTP GDP Pi H+ N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate ATP Adenosine diphosphate ATP L-Glutamine H2O AMP PPi L-Glutamic acid H+ Guanosine monophosphate ATP ADP Guanosine diphosphate ATP ADP Guanosine triphosphate H2O H2O dGDP ATP ADP dGTP H2O dGDP Pi H+ H2O H+ Adenosine triphosphate H2O dATP Adenosine diphosphate H2O dADP H2O dADP ATP ADP dATP Chorismate Prephenate 1-Methylhistidine Magnesium Magnesium Potassium Magnesium Magnesium Magnesium Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium 4Fe-4S Magnesium an N10-formyl- tetrahydrofolate a tetrahydrofolate a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein PRPP Biosynthesis Folate Biosynthesis Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase 2 subunit alpha Zinc (II) ion
dGTP purF purD purT purL purM purK purE purC purB purH purH guaB purA purB adk guaA gmk ndk nrdD nrdB ndk nrdF atpE atpF atpB atpC atpH atpA atpG atpD nrdD nrdD nrdB nrdE nrdF ndk Phosphoribosyl pyrophosphate Water L-Glutamine 5- Phosphoribosylamine L-Glutamic acid Pyrophosphate Glycine Adenosine triphosphate N1-(5-phospho- β-D- ribosyl)glycinamide Phosphate Adenosine diphosphate Hydrogen Ion Adenosine triphosphate Formic acid 5'- Phosphoribosyl- N- formylglycinamide Adenosine diphosphate Phosphate Hydrogen Ion Water L-Glutamine Adenosine triphosphate 2-(Formamido)- N1-(5-phospho- D- ribosyl)acetamidine L-Glutamic acid Phosphate Adenosine diphosphate Hydrogen Ion Adenosine triphosphate 5-Aminoimidazole ribonucleotide Phosphate Adenosine diphosphate Hydrogen Ion Hydrogen carbonate Adenosine triphosphate N5- Carboxyaminoimidazole ribonucleotide Adenosine diphosphate Phosphate Hydrogen Ion 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid Adenosine triphosphate SAICAR Phosphate Adenosine diphosphate Hydrogen Ion AICAR Fumaric acid FAICAR Inosinic acid Water NAD Water NADH Hydrogen Ion Xanthylic acid L-Aspartic acid Guanosine triphosphate Guanosine diphosphate Phosphate Hydrogen Ion N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate Adenosine triphosphate Adenosine diphosphate Adenosine triphosphate L-Glutamine Water Adenosine monophosphate Pyrophosphate L-Glutamic acid Hydrogen Ion Guanosine monophosphate Adenosine triphosphate Adenosine diphosphate Guanosine diphosphate Adenosine triphosphate Adenosine diphosphate Guanosine triphosphate Water Water dGDP Adenosine triphosphate Adenosine diphosphate dGTP Water dGDP Phosphate Hydrogen Ion Water Hydrogen Ion Adenosine triphosphate Water dATP Adenosine diphosphate Water dADP Water dADP Adenosine triphosphate Adenosine diphosphate dATP Chorismate Prephenate 1-Methylhistidine an N10-formyl- tetrahydrofolate a tetrahydrofolate a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin-like protein an oxidized NrdH glutaredoxin-like protein a reduced flavodoxin an oxidized flavodoxin reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin-like protein an oxidized NrdH glutaredoxin-like protein PRPP Biosynthesis Folate Biosynthesis nrdD nrdE
dGTP purF purD purT purL purM purK purE purC purB purH purH guaB purA purB adk guaA gmk ndk nrdD nrdB ndk nrdF atpE atpF atpB atpC atpH atpA atpG atpD nrdD nrdD nrdB nrdE nrdF ndk PRPP H2O Gln 5-PPRSA Glu PPi Gly ATP N15hg Pi ADP H+ ATP Formate 5PPNFG ADP Pi H+ H2O Gln ATP 2FN5PDR Glu Pi ADP H+ ATP 5-AnRbn Pi ADP H+ HCO3- ATP N5Cr ADP Pi H+ CR Asp ATP SAICAR Pi ADP H+ AICAR Fumarat FAICAR Imp H2O NAD H2O NADH H+ XntylcA Asp GTP GDP Pi H+ N6AMP Fumarat AMP ATP ADP ATP Gln H2O AMP PPi Glu H+ GSMP ATP ADP GDP ATP ADP GTP H2O H2O dGDP ATP ADP dGTP H2O dGDP Pi H+ H2O H+ ATP H2O dATP ADP H2O dADP H2O dADP ATP ADP dATP Chorism Prephen 1-Mhis Mg2+ Mg2+ K+ Mg2+ Mg2+ Mg2+ Mg2+ Mg2+ ATP dGTP Tm5TP K+ Mg2+ Zinc 4Fe-4S Mg2+ ATP dGTP Tm5TP K+ Mg2+ 4Fe-4S Mg2+ AFT AT ARF AOF RT OT ARNGLP AONGLP ARF AOF RT OT ARNGLP AONGLP PW000909 PW000908 nrdD nrdE Zinc
dGTP purF purD purT purL purM purK purE purC purB purH purH guaB purA purB adk guaA gmk ndk nrdD nrdB ndk nrdF atpE atpF atpB atpC atpH atpA atpG atpD nrdD nrdD nrdB nrdE nrdF ndk PRPP H2O Gln 5-PPRSA Glu Ppi Gly ATP N15hg Pi ADP H+ ATP Formate 5PPNFG ADP Pi H+ H2O Gln ATP 2FN5PDR Glu Pi ADP H+ ATP 5-AnRbn Pi ADP H+ HCO3 ATP N5Cr ADP Pi H+ CR Asp ATP SAICAR Pi ADP H+ AICAR Fumarat FAICAR Imp H2O NAD H2O NADH H+ XntylcA Asp GTP GDP Pi H+ N6AMP Fumarat AMP ATP ADP ATP Gln H2O AMP Ppi Glu H+ GSMP ATP ADP GDP ATP ADP GTP H2O H2O dGDP ATP ADP dGTP H2O dGDP Pi H+ H2O H+ ATP H2O dATP ADP H2O dADP H2O dADP ATP ADP dATP Chorism Prephen 1-Mhis AFT AT ARF AOF RT OT ARNGLP AONGLP ARF AOF RT OT ARNGLP AONGLP PW000909 PW000908 nrdD nrdE