Farnesyl pyrophosphate + Isopentenyl pyrophosphate → Geranylgeranyl-PP + Pyrophosphate
Farnesyl pyrophosphate + 3 Isopentenyl pyrophosphate → All-trans-hexaprenyl diphosphate + 3 Pyrophosphate
Farnesyl pyrophosphate + 13 Isopentenyl pyrophosphate → di-trans, poly-cis-polyprenyl diphosphate (C80) + 13 Pyrophosphate
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1
2 Acetyl-CoA ↔ Acetoacetyl-CoA + Coenzyme A
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2
Adenosine triphosphate + Mevalonic acid → Adenosine diphosphate + Mevalonic acid-5P
Adenosine triphosphate + Mevalonic acid-5P → (R)-5-Diphosphomevalonic acid + Adenosine diphosphate
(R)-5-Diphosphomevalonic acid + Adenosine triphosphate → Adenosine diphosphate + Carbon dioxide + Isopentenyl pyrophosphate + Phosphate
Acetoacetyl-CoA + Acetyl-CoA + Water → 3-Hydroxy-3-methylglutaryl-CoA + Coenzyme A
Terpenoid Backbone Biosynthesis 1540198538
Hexaprenyl pyrophosphate synthase, mitochondrial
ditrans,polycis-polyprenyl diphosphate synthase RER2
dehydrodolichyl diphosphate syntase complex subunit NUS1
ditrans,polycis-polyprenyl diphosphate synthase SRT1
Isopentenyl pyrophosphate ↔ Dimethylallylpyrophosphate
Dimethylallylpyrophosphate + Isopentenyl pyrophosphate → Geranyl-PP + Pyrophosphate
Geranyl-PP + Isopentenyl pyrophosphate → Farnesyl pyrophosphate + Pyrophosphate
3-hydroxy-3-methylglutaryl-coenzyme A reductase
di-trans, poly-cis-polyprenyl diphosphate (C80)
dehydrodolichyl diphosphate synthase complex
3-Hydroxy-3-methylglutaryl-CoA + NADPH → Coenzyme A + Mevalonic acid + NADP