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Pathway Description
Selenocompound Metabolism
Drosophila melanogaster
Metabolic Pathway
References
Selenocompound Metabolism References
Hoefig CS, Renko K, Kohrle J, Birringer M, Schomburg L: Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture. J Nutr Biochem. 2011 Oct;22(10):945-55. doi: 10.1016/j.jnutbio.2010.08.006. Epub 2010 Dec 28.
Pubmed: 21190829
McKenzie MJ, Hunter DA, Pathirana R, Watson LM, Joyce NI, Matich AJ, Rowan DD, Brummell DA: Accumulation of an organic anticancer selenium compound in a transgenic Solanaceous species shows wider applicability of the selenocysteine methyltransferase transgene from selenium hyperaccumulators. Transgenic Res. 2009 Jun;18(3):407-24. doi: 10.1007/s11248-008-9233-0. Epub 2008 Dec 3.
Pubmed: 19051051
Pinto JT, Lee JI, Sinha R, MacEwan ME, Cooper AJ: Chemopreventive mechanisms of alpha-keto acid metabolites of naturally occurring organoselenium compounds. Amino Acids. 2011 Jun;41(1):29-41. doi: 10.1007/s00726-010-0578-3. Epub 2010 Apr 10.
Pubmed: 20383543
Suzuki KT, Kurasaki K, Suzuki N: Selenocysteine beta-lyase and methylselenol demethylase in the metabolism of Se-methylated selenocompounds into selenide. Biochim Biophys Acta. 2007 Jul;1770(7):1053-61. doi: 10.1016/j.bbagen.2007.03.007. Epub 2007 Mar 23.
Pubmed: 17451884
Gromer S, Gross JH: Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium. J Biol Chem. 2002 Mar 22;277(12):9701-6. doi: 10.1074/jbc.M109234200. Epub 2002 Jan 8.
Pubmed: 11782468
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