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Malate dehydrogenase, mitochondrial Malate dehydrogenase, mitochondrial Serine/threonine- protein kinase mTOR Hypoxia-inducible factor 1-alpha inhibitor Myc proto-oncogene protein Mitochondrial pyruvate carrier 1 Mitochondrial pyruvate carrier 1 Neutral amino acid transporter B(0) Neutral amino acid transporter A Sodium-coupled neutral amino acid transporter 5 C-Myc-binding protein Monocarboxylate transporter 1 Y+L amino acid transporter 1 Pyruvate dehydrogenase complex Citrate synthase, mitochondrial Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial Oxoglutarate dehydrogenase complex Succinyl-CoA ligase Fumarate hydratase, mitochondrial Pyruvate carboxylase, mitochondrial Aconitate hydratase, mitochondrial Aconitate hydratase, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Pyruvate dehydrogenase complex Citrate synthase, mitochondrial Fumarate hydratase, mitochondrial Pyruvate carboxylase, mitochondrial Aconitate hydratase, mitochondrial Aconitate hydratase, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Glutaminase liver isoform, mitochondrial Glutamate dehydrogenase 1, mitochondrial Aspartate aminotransferase, mitochondrial Unknown Unknown NADP-dependent malic enzyme L-lactate dehydrogenase A chain Isocitrate dehydrogenase [NADP], mitochondrial ATP-citrate synthase ATP-citrate synthase Hydroxymethylglutaryl- CoA synthase, mitochondrial NADP-dependent malic enzyme Cholesterol 7-alpha- monooxygenase 7-alpha- hydroxycholest- 4-en-3-one 12-alpha- hydroxylase Sterol 26-hydroxylase, mitochondrial Lipoprotein lipase Long-chain- fatty-acid--CoA ligase 1 Peroxisomal bifunctional enzyme Cytochrome P450 4A11 Non-specific lipid-transfer protein Peroxisomal acyl-coenzyme A oxidase 2 Carnitine O- palmitoyltransferase 2, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Pyruvic acid FADH2 Pyruvic acid FADH2 Pyruvic acid Pyruvic acid L-Glutamine L-Glutamine L-Glutamine L-Glutamine L-Lactic acid L-Lactic acid L-Glutamine L-Glutamine L-Leucine L-Leucine CoA NAD Acetyl-CoA CO2 NADH H2O Oxalacetic acid Citric acid CoA Isocitric acid NAD Oxoglutaric acid CO2 NADH H+ NAD CoA Succinyl-CoA NADH H+ CO2 Pi GDP CoA GTP L-Malic acid Fumaric acid H2O NAD NADH H+ ATP HCO3- ADP Pi cis-Aconitic acid H2O H2O Q FAD FADH2 Fumaric acid QH2 CoA NAD Acetyl-CoA CO2 NADH H2O Oxalacetic acid Citric acid CoA L-Malic acid Fumaric acid H2O NAD NADH H+ ATP HCO3- ADP Pi cis-Aconitic acid H2O H2O Isocitric acid Q FAD FADH2 Fumaric acid QH2 L-Glutamic acid NH3 NAD NADH Hydrogen Ion Oxoglutaric acid Oxalacetic acid Oxoglutaric acid L-Aspartic acid Pyruvic acid Oxoglutaric acid L-Alanine NADP NADPH H+ CO2 Pyruvic acid NADH H+ NAD CO2 Citric acid CoA ATP Oxalacetic acid ADP Acetyl-CoA CoA ATP Oxalacetic acid ADP Acetyl-CoA Oxygen L-Glutamine Thiamine pyrophosphate Lipoamide FAD Magnesium Thiamine pyrophosphate Lipoamide FAD Biotin Manganese 4Fe-4S 4Fe-4S Thiamine pyrophosphate Lipoamide FAD Biotin Manganese 4Fe-4S 4Fe-4S Pyridoxal 5'-phosphate Manganese 4Fe-4S Manganese Heme Heme Heme Magnesium Heme FAD FAD FAD Aconitate hydratase, mitochondrial Glycolysis Mitochondrial Electron Transport Chain Glycolysis Mitochondrial Electron Transport Chain Succinic acid Inner mitochondrial membrane Mitochondrial intermembrane space Cytosol Mitochondrial matrix Mitochondrion Intracellular Space Inner mitochondrial membrane Outer mitochondrial membrane Inner mitochondrial membrane Mitochondrial intermembrane space Cytosol Mitochondrial matrix Mitochondrion Intracellular Space Inner mitochondrial membrane Outer mitochondrial membrane Pseudo-Hypoxia Mutant Aconitase Mutant Aconitase Lipid Synthesis
Mitochondria Mitochondria MDH2 MDH2 MTOR HIF1AN MYC MPC1 MPC1 SLC1A5 SLC1A4 SLC38A5, SN2 MYCBP SLC16A1 SLC7A7 PDHA1 CS IDH3A IDH3B IDH3G OGDH SUCLG1 SUCLG2 FH PC ACO2 ACO2 SDHD SDHC SDHB SDHA PDHA1 CS FH PC ACO2 ACO2 SDHD SDHC SDHB SDHA GLS2 GLUD1 GOT2 Unknown Unknown ME1 LDHA IDH2 ACLY ACLY HMGCS2 ME1 CYP7A1 CYP8B1 CYP27A1 LPL ACSL1 EHHADH CYP4A11 SCP2 ACOX2 CPT2 ACADL ACADM Pyruvic acid FADH Pyruvic acid FADH Pyruvic acid Pyruvic acid L-Glutamine L-Glutamine L-Glutamine L-Glutamine L-Lactic acid L-Lactic acid L-Glutamine L-Glutamine L-Leucine L-Leucine Coenzyme A NAD Acetyl-CoA Carbon dioxide NADH Water Oxalacetic acid Citric acid Coenzyme A Isocitric acid NAD Oxoglutaric acid Carbon dioxide NADH Hydrogen Ion NAD Coenzyme A Succinyl-CoA NADH Hydrogen Ion Carbon dioxide Phosphate Guanosine diphosphate Coenzyme A Guanosine triphosphate L-Malic acid Fumaric acid Water NAD NADH Hydrogen Ion Adenosine triphosphate Hydrogen carbonate Adenosine diphosphate Phosphate cis-Aconitic acid Water Water Coenzyme Q10 FAD FADH Fumaric acid QH2 Coenzyme A NAD Acetyl-CoA Carbon dioxide NADH Water Oxalacetic acid Citric acid Coenzyme A L-Malic acid Fumaric acid Water NAD NADH Hydrogen Ion Adenosine triphosphate Hydrogen carbonate Adenosine diphosphate Phosphate cis-Aconitic acid Water Water Isocitric acid Coenzyme Q10 FAD FADH Fumaric acid QH2 L-Glutamic acid Ammonia NAD NADH Hydrogen Ion Oxoglutaric acid Oxalacetic acid Oxoglutaric acid L-Aspartic acid Pyruvic acid Oxoglutaric acid L-Alanine NADP NADPH Hydrogen Ion Carbon dioxide Pyruvic acid NADH Hydrogen Ion NAD Carbon dioxide Citric acid Coenzyme A Adenosine triphosphate Oxalacetic acid Adenosine diphosphate Acetyl-CoA Coenzyme A Adenosine triphosphate Oxalacetic acid Adenosine diphosphate Acetyl-CoA Oxygen L-Glutamine ACO2 Glycolysis Mitochondrial Electron Transport Chain Glycolysis Mitochondrial Electron Transport Chain Succinic acid