L-Valine
type: SmallMoleculeReference
xref: Reference/CAS 72-18-4
xref: Reference/PubChem-compound 6287
xref: Reference/ChemSpider 6050
xref: Reference/HMDB HMDB0000883
xref: Reference/KEGG Compound C00183
xref: Reference/ChEBI CHEBI 16414
xref: Reference/BioCyc VAL
chemical formula: C5H11NO2
molecular weight: 117.07898
structure: ChemicalStructure/PW C000704

Acetic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15366
xref: Reference/BioCyc ACET
xref: Reference/CAS 64-19-7
xref: Reference/KEGG Compound C00033
xref: Reference/ChemSpider 171
xref: Reference/HMDB HMDB0000042
xref: Reference/PubChem-compound 176
chemical formula: C2H4O2
molecular weight: 60.02113
structure: ChemicalStructure/PW C000029

ChemicalStructure/PW C000448
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CS)C(O)=O

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Compound/PW C001420 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 2.0

Compound/Generic71 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carboxylate
stoichiometric coefficient: 1.0

Reference/BioCyc CYS
type: UnificationXref
id: CYS
db: BioCyc

Reference/SMPDB SMP0122608
type: UnificationXref
id: SMP0122608
db: SMPDB

Reference/CAS 64-19-7
type: UnificationXref
id: 64-19-7
db: CAS

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Compound/PW C108766 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-2-Aminoadipate
stoichiometric coefficient: 1.0

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Compound/PW C000032 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 3.0

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Reference/HMDB HMDB0001185
type: UnificationXref
id: HMDB0001185
db: HMDB

Reference/PubChem-compound 8795
type: UnificationXref
id: 8795
db: PubChem-compound

Reference/ChEBI CHEBI 18203
type: UnificationXref
id: CHEBI:18203
db: ChEBI

Reference/PubChem-compound 8794
type: UnificationXref
id: 8794
db: PubChem-compound

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

Reference/PubChem-compound 8793
type: UnificationXref
id: 8793
db: PubChem-compound

Compound/PW C108772 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: O-Carbamoyl-deacetylcephalosporin C
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/PubChem-compound 1004
type: UnificationXref
id: 1004
db: PubChem-compound

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Compound/PW C000414 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 3.0

Compound/PW C000862 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbamoyl phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 8798
type: UnificationXref
id: 8798
db: PubChem-compound

Reference/PubChem-compound 8797
type: UnificationXref
id: 8797
db: PubChem-compound

Reference/PathWhiz PW123921
type: UnificationXref
id: PW123921
db: PathWhiz

Water
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Water

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/CAS 1476-46-6
type: UnificationXref
id: 1476-46-6
db: CAS

Penicillin N
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Penicillin N

Reference/PubChem-compound 6287
type: UnificationXref
id: 6287
db: PubChem-compound

Compound/PW C108770 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deacetoxycephalosporin C
stoichiometric coefficient: 1.0

Succinate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Succinate

S-Adenosylmethionine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 24762165
xref: Reference/KEGG Compound C00019
xref: Reference/ChemSpider 31983
xref: Reference/ChEBI CHEBI 15414
xref: Reference/CAS 485-80-3
xref: Reference/BioCyc S-ADENOSYLMETHIONINE
xref: Reference/HMDB HMDB0001185
chemical formula: C15H23N6O5S
molecular weight: 399.14505
structure: ChemicalStructure/PW C000921

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/ChEBI CHEBI 17561
type: UnificationXref
id: CHEBI:17561
db: ChEBI

Compound/Generic593 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Penicilloic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5872
type: UnificationXref
id: 5872
db: PubChem-compound

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

Carbon dioxide
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Carbon dioxide

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Compound/PW C108775 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: 6-Aminopenicillanic acid
stoichiometric coefficient: 1.0

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Reference/ChemSpider 272
type: UnificationXref
id: 272
db: ChemSpider

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

CmcI hydroxylase
type: Protein
cellular location: Cytoplasm
entity reference: CmcI hydroxylase

Compound/PW C000029 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetic acid
stoichiometric coefficient: 1.0

Adenosine monophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine monophosphate

Reference/BioCyc ADENOSYL-HOMO-CYS
type: UnificationXref
id: ADENOSYL-HOMO-CYS
db: BioCyc

Reference/CAS 485-80-3
type: UnificationXref
id: 485-80-3
db: CAS

Reference/PubChem-compound 5862
type: UnificationXref
id: 5862
db: PubChem-compound

Reference/KEGG Compound C06567
type: UnificationXref
id: C06567
db: KEGG Compound

Compound/PW C000921 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylmethionine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 2286
type: UnificationXref
id: CHEBI:2286
db: ChEBI

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/HMDB HMDB0001096
type: UnificationXref
id: HMDB0001096
db: HMDB

delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine

L-Valine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: L-Valine

Carbamoyl phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 278
xref: Reference/BioCyc CARBAMOYL-P
xref: Reference/ChemSpider 272
xref: Reference/HMDB HMDB0001096
xref: Reference/CAS 590-55-6
xref: Reference/KEGG Compound C00169
xref: Reference/ChEBI CHEBI 17672
chemical formula: CH4NO5P
molecular weight: 140.98271
structure: ChemicalStructure/PW C000862

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

ChemicalStructure/PW C000921
type: ChemicalStructure
structure format: SMILES

Reference/CAS 979-92-0
type: UnificationXref
id: 979-92-0
db: CAS

S-Adenosylhomocysteine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: S-Adenosylhomocysteine

Compound/PW C108774 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cephamycin C
stoichiometric coefficient: 1.0

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

Reference/UniProt F8LFQ4
type: UnificationXref
id: F8LFQ4
db: UniProt

S-Adenosylhomocysteine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 25246222
xref: Reference/ChemSpider 388301
xref: Reference/BioCyc ADENOSYL-HOMO-CYS
xref: Reference/CAS 979-92-0
xref: Reference/KEGG Compound C00021
xref: Reference/ChEBI CHEBI 16680
xref: Reference/HMDB HMDB0000939
chemical formula: C14H20N6O5S
molecular weight: 384.12158
structure: ChemicalStructure/PW C000749

Reference/HMDB HMDB0000574
type: UnificationXref
id: HMDB0000574
db: HMDB

Deacetoxycephalosporin C synthase
type: ProteinReference
xref: Reference/UniProt F8JTW8
organism: Streptomyces cattleya

CefF protein
type: ProteinReference
xref: Reference/UniProt F8JTW2
organism: Streptomyces cattleya

3'-hydroxymethylcephem-O-carbamoyltransferase
type: ProteinReference
organism: Streptomyces cattleya

N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
type: ProteinReference
xref: Reference/UniProt F8JTW5
organism: Streptomyces cattleya

Isopenicillin N synthase
type: ProteinReference
xref: Reference/UniProt F8JTW4
organism: Streptomyces cattleya

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Isopenicillin N epimerase
type: ProteinReference
xref: Reference/UniProt F8JTW7
organism: Streptomyces cattleya

Reference/CAS 7664-38-2
type: UnificationXref
id: 7664-38-2
db: CAS

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

L-2-Aminoadipate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 37023
xref: Reference/PubChem-compound 4207
xref: Reference/CAS 542-32-5
chemical formula: C6H11NO4
molecular weight: 161.0688
structure: ChemicalStructure/PW C108766

delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 7889
xref: Reference/ChEBI CHEBI 28496
chemical formula: C14H25N3O6S
molecular weight: 363.1464
structure: ChemicalStructure/PW C108767

Isopenicillin N
type: SmallMoleculeReference
xref: Reference/PubChem-compound 7890
xref: Reference/ChEBI CHEBI 18165
chemical formula: C14H21N3O6S
molecular weight: 359.1151
structure: ChemicalStructure/PW C108768

Penicillin N
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 18203
xref: Reference/PubChem-compound 8793
xref: Reference/CAS 525-94-0
chemical formula: C14H21N3O6S
molecular weight: 359.1151
structure: ChemicalStructure/PW C108769

Compound/Generic592 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Penicillin
stoichiometric coefficient: 1.0

Isopenicillin N synthase
type: Protein
cellular location: Cytoplasm
entity reference: Isopenicillin N synthase

Reference/CAS 551-16-6
type: UnificationXref
id: 551-16-6
db: CAS

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Reference/ChEBI CHEBI 15414
type: UnificationXref
id: CHEBI:15414
db: ChEBI

Reference/ChEBI CHEBI 15776
type: UnificationXref
id: CHEBI:15776
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChemSpider 6050
type: UnificationXref
id: 6050
db: ChemSpider

Deacetoxycephalosporin C
type: SmallMoleculeReference
xref: Reference/PubChem-compound 8794
xref: Reference/ChEBI CHEBI 18229
xref: Reference/CAS 26924-74-3
chemical formula: C14H19N3O6S
molecular weight: 357.09946
structure: ChemicalStructure/PW C108770

Deacetylcephalosporin C
type: SmallMoleculeReference
xref: Reference/CAS 1476-46-6
xref: Reference/ChEBI CHEBI 18065
xref: Reference/PubChem-compound 6007
chemical formula: C14H19N3O7S
molecular weight: 373.09436
structure: ChemicalStructure/PW C108771

Unknown
type: ProteinReference
organism: Streptomyces cattleya

O-Carbamoyl-deacetylcephalosporin C
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 7678
xref: Reference/PubChem-compound 8797
chemical formula: C15H20N4O8S
molecular weight: 416.1002
structure: ChemicalStructure/PW C108772

7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 2286
xref: Reference/PubChem-compound 8798
chemical formula: C15H20N4O9S
molecular weight: 432.0951
structure: ChemicalStructure/PW C108773

Cephamycin C
type: SmallMoleculeReference
xref: Reference/PubChem-compound 8795
xref: Reference/ChEBI CHEBI 3543
xref: Reference/CAS 38429-35-5
chemical formula: C16H22N4O9S
molecular weight: 446.11075
structure: ChemicalStructure/PW C108774

6-Aminopenicillanic acid
type: SmallMoleculeReference
xref: Reference/CAS 551-16-6
xref: Reference/ChEBI CHEBI 16705 30938
xref: Reference/PubChem-compound 5872
chemical formula: C8H12N2O3SV
molecular weight: 267.00082
structure: ChemicalStructure/PW C108775

CmcI hydroxylase
type: ProteinReference
xref: Reference/UniProt F8LFQ4
organism: Streptomyces cattleya

Beta-lactamase class A-like protein
type: ProteinReference
organism: Streptomyces cattleya

Putative penicillin acylase
type: ProteinReference
organism: Streptomyces cattleya

6-Aminopenicillanic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: 6-Aminopenicillanic acid

Penicillin
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Penicillin

ChemicalStructure/PW C108716
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(O)=O

Beta-lactamase class A-like protein
type: Protein
cellular location: Cytoplasm
entity reference: Beta-lactamase class A-like protein

Oxygen
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Oxygen

Reference/KEGG Compound C00019
type: UnificationXref
id: C00019
db: KEGG Compound

Reference/ChEBI CHEBI 15741
type: UnificationXref
id: CHEBI:15741
db: ChEBI

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine triphosphate

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/BioCyc S-ADENOSYLMETHIONINE
type: UnificationXref
id: S-ADENOSYLMETHIONINE
db: BioCyc

Compound/PW C000134 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6007
type: UnificationXref
id: 6007
db: PubChem-compound

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

ChemicalStructure/PW C001441
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Penicilloic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Penicilloic acid

Cephalosporin C
type: SmallMoleculeReference
xref: Reference/PubChem-compound 4170
xref: Reference/ChEBI CHEBI 15776
xref: Reference/CAS 61-24-5
chemical formula: C16H21N3O8S
molecular weight: 415.10495
structure: ChemicalStructure/PW C108780

Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Isopenicillin N
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Isopenicillin N

Reference/ChemSpider 388301
type: UnificationXref
id: 388301
db: ChemSpider

N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
type: Protein
cellular location: Cytoplasm
entity reference: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase

Reference/PubChem-compound 4170
type: UnificationXref
id: 4170
db: PubChem-compound

Reference/ChEBI CHEBI 18229
type: UnificationXref
id: CHEBI:18229
db: ChEBI

Carbamoyl phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Carbamoyl phosphate

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/KEGG Compound C00021
type: UnificationXref
id: C00021
db: KEGG Compound

Reference/ChemSpider 5653
type: UnificationXref
id: 5653
db: ChemSpider

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Compound/PW C000704 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Valine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 26078
type: UnificationXref
id: CHEBI:26078
db: ChEBI

Reference/BioCyc ACET
type: UnificationXref
id: ACET
db: BioCyc

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Compound/PW C108773 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 28496
type: UnificationXref
id: CHEBI:28496
db: ChEBI

Deacetoxycephalosporin C
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Deacetoxycephalosporin C

Deacetylcephalosporin C
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Deacetylcephalosporin C

Reference/ChEBI CHEBI 16414
type: UnificationXref
id: CHEBI:16414
db: ChEBI

Reference/CAS 52-90-4
type: UnificationXref
id: 52-90-4
db: CAS

Reference/KEGG Compound C00033
type: UnificationXref
id: C00033
db: KEGG Compound

Reference/KEGG Compound C00395
type: UnificationXref
id: C00395
db: KEGG Compound

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

Compound/PW C108771 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deacetylcephalosporin C
stoichiometric coefficient: 1.0

Carboxylate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 29067

Compound/PW C001316 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 3543
type: UnificationXref
id: CHEBI:3543
db: ChEBI

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

O-Carbamoyl-deacetylcephalosporin C
type: SmallMolecule
cellular location: Cytoplasm
entity reference: O-Carbamoyl-deacetylcephalosporin C

Reference/BioCyc CARBAMOYL-P
type: UnificationXref
id: CARBAMOYL-P
db: BioCyc

Reference/ChEBI CHEBI 18165
type: UnificationXref
id: CHEBI:18165
db: ChEBI

Reference/CAS 61-24-5
type: UnificationXref
id: 61-24-5
db: CAS

Reference/KEGG Compound C00169
type: UnificationXref
id: C00169
db: KEGG Compound

Reference/HMDB HMDB0000939
type: UnificationXref
id: HMDB0000939
db: HMDB

Compound/PW C000749 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylhomocysteine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000862
type: ChemicalStructure
structure format: SMILES
structure data: NC(=O)OP(O)(O)=O

3'-hydroxymethylcephem-O-carbamoyltransferase
type: Protein
cellular location: Cytoplasm
entity reference: 3'-hydroxymethylcephem-O-carbamoyltransferase

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Reference/CAS 542-32-5
type: UnificationXref
id: 542-32-5
db: CAS

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/PubChem-compound 7890
type: UnificationXref
id: 7890
db: PubChem-compound

Compound/PW C108716 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinate
stoichiometric coefficient: 1.0

Compound/PW C000170 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 3.0

ChemicalStructure/PW C000029
type: ChemicalStructure
structure format: SMILES
structure data: CC(O)=O

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C001441 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphoric acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000704
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)[C@H](N)C(O)=O

Reference/CAS 72-18-4
type: UnificationXref
id: 72-18-4
db: CAS

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

Reference/TAXONOMY 29303
type: UnificationXref
id: 29303
db: TAXONOMY

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

Reference/KEGG Compound C00183
type: UnificationXref
id: C00183
db: KEGG Compound

L-Cysteine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: L-Cysteine

ChemicalStructure/PW C108768
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C108767
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C108766
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCCC(O)=O)C(O)=O

Reference/CAS 590-55-6
type: UnificationXref
id: 590-55-6
db: CAS

Reference/CAS 525-94-0
type: UnificationXref
id: 525-94-0
db: CAS

ChemicalStructure/PW C108769
type: ChemicalStructure
structure format: SMILES

Streptomyces cattleya
type: BioSource
xref: Reference/TAXONOMY 29303

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Cephamycin C
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Cephamycin C

Reference/PubChem-compound 7889
type: UnificationXref
id: 7889
db: PubChem-compound

Phosphoric acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Phosphoric acid

CefF protein
type: Protein
cellular location: Cytoplasm
entity reference: CefF protein

Pyrophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pyrophosphate

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

ChemicalStructure/PW C108771
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

ChemicalStructure/PW C108770
type: ChemicalStructure
structure format: SMILES

Compound/PW C001065 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 1.0

ChemicalStructure/PW C108775
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C108774
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C108773
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C108772
type: ChemicalStructure
structure format: SMILES

Penicillin and Cephalosporin Biosynthesis
type: Pathway
pathway order: PathwayEnzymeReaction/2460342
pathway order: PathwayEnzymeReaction/2460350
pathway order: PathwayEnzymeReaction/2460351
pathway order: PathwayEnzymeReaction/2460349
pathway order: PathwayEnzymeReaction/2460347
pathway order: PathwayEnzymeReaction/2460413
pathway order: PathwayEnzymeReaction/2460411
pathway order: PathwayEnzymeReaction/2460346
pathway order: PathwayEnzymeReaction/2460412
pathway order: PathwayEnzymeReaction/2460343
pathway order: PathwayEnzymeReaction/2460344
pathway order: PathwayEnzymeReaction/2460410
pathway component: Reaction212642
pathway component: Reaction212643
pathway component: 3.5.1.11
pathway component: Reaction212634
pathway component: Reaction212645
pathway component: Reaction212635
pathway component: Reaction212636
pathway component: Reaction212637
pathway component: Reaction212638
pathway component: ReactionCatalysis202267
pathway component: ReactionCatalysis202268
pathway component: ReactionCatalysis202269
pathway component: ReactionCatalysis202263
pathway component: ReactionCatalysis202264
pathway component: ReactionCatalysis202265
pathway component: Reaction212640
pathway component: ReactionCatalysis202266
pathway component: Reaction212641
pathway component: ReactionCatalysis202270
pathway component: ReactionCatalysis202271
pathway component: ReactionCatalysis202272
pathway component: ReactionCatalysis202273
pathway component: 2.1.3.7
xref: Reference/SMPDB SMP0122608
xref: Reference/PathWhiz PW123921
organism: Streptomyces cattleya

Reference/HMDB HMDB0000042
type: UnificationXref
id: HMDB0000042
db: HMDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChEBI CHEBI 15366
type: UnificationXref
id: CHEBI:15366
db: ChEBI

Reference/ChemSpider 31983
type: UnificationXref
id: 31983
db: ChemSpider

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Reference/ChEBI CHEBI 16705 30938
type: UnificationXref
id: CHEBI:16705 30938
db: ChEBI

Compound/PW C108769 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Penicillin N
stoichiometric coefficient: 1.0

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/ChemSpider 979
type: UnificationXref
id: 979
db: ChemSpider

ReactionCatalysis202270
type: Catalysis
controller: Isopenicillin N epimerase
controlled: Reaction212642
control type: ACTIVATION

ReactionCatalysis202271
type: Catalysis
controller: Beta-lactamase class A-like protein
controlled: Reaction212643
control type: ACTIVATION

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

ReactionCatalysis202272
type: Catalysis
controller: Putative penicillin acylase
controlled: 3.5.1.11
control type: ACTIVATION

Reference/CAS 110-15-6
type: UnificationXref
id: 110-15-6
db: CAS

ChemicalStructure/PW C108780
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis202273
type: Catalysis
controller: Unknown
controlled: Reaction212645
control type: ACTIVATION

Phosphoric acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/ChEBI CHEBI 26078
xref: Reference/CAS 7664-38-2
xref: Reference/PubChem-compound 1004
xref: Reference/ChemSpider 979
xref: Reference/HMDB HMDB0002142
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001441

Reference/PubChem-compound 4207
type: UnificationXref
id: 4207
db: PubChem-compound

Putative penicillin acylase
type: Protein
cellular location: Cytoplasm
entity reference: Putative penicillin acylase

Oxoglutaric acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Oxoglutaric acid

Reference/ChemSpider 171
type: UnificationXref
id: 171
db: ChemSpider

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 37023
type: UnificationXref
id: CHEBI:37023
db: ChEBI

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

Reference/PubChem-compound 278
type: UnificationXref
id: 278
db: PubChem-compound

Isopenicillin N epimerase
type: Protein
cellular location: Cytoplasm
entity reference: Isopenicillin N epimerase

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/CAS 38429-35-5
type: UnificationXref
id: 38429-35-5
db: CAS

L-2-Aminoadipate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: L-2-Aminoadipate

Reference/CAS 26924-74-3
type: UnificationXref
id: 26924-74-3
db: CAS

Reference/PubChem-compound 3344
type: UnificationXref
id: 3344
db: PubChem-compound

Reference/BioCyc VAL
type: UnificationXref
id: VAL
db: BioCyc

Reference/ChEBI CHEBI 17672
type: UnificationXref
id: CHEBI:17672
db: ChEBI

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/ChEBI CHEBI 7678
type: UnificationXref
id: CHEBI:7678
db: ChEBI

Compound/PW C108768 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Isopenicillin N
stoichiometric coefficient: 1.0

Carboxylate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Carboxylate

Reaction212634
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000704 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000448 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytoplasm/Stoichiometry/3.0
participant stoichiometry: Compound/PW C108766 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108767 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytoplasm/Stoichiometry/3.0
participant stoichiometry: Compound/PW C000032 Cytoplasm/Stoichiometry/3.0
right: delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine
right: Adenosine monophosphate
right: Pyrophosphate
spontaneous: false
left: L-Valine
left: Water
left: L-Cysteine
left: Adenosine triphosphate
left: L-2-Aminoadipate
name: 3 Adenosine triphosphate + L-2-Aminoadipate + L-Cysteine + L-Valine + Water ↔ 3 Adenosine monophosphate + 3 Pyrophosphate + delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine
conversion direction: REVERSIBLE

L-Cysteine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000574
xref: Reference/CAS 52-90-4
xref: Reference/KEGG Compound C00097
xref: Reference/BioCyc CYS
xref: Reference/ChemSpider 5653
xref: Reference/PubChem-compound 5862
xref: Reference/ChEBI CHEBI 17561
chemical formula: C3H7NO2S
molecular weight: 121.01975
structure: ChemicalStructure/PW C000448

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reaction212635
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001065 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108768 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/2.0
participant stoichiometry: Compound/PW C108767 Cytoplasm/Stoichiometry/1.0
right: Water
right: Isopenicillin N
spontaneous: false
left: delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine
left: Oxygen
name: Oxygen + delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine ↔ Isopenicillin N + 2 Water
conversion direction: REVERSIBLE

Reaction212636
type: BiochemicalReaction
participant stoichiometry: Compound/PW C108768 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108769 Cytoplasm/Stoichiometry/1.0
right: Penicillin N
spontaneous: false
left: Isopenicillin N
name: Isopenicillin N ↔ Penicillin N
conversion direction: REVERSIBLE

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

Reaction212637
type: BiochemicalReaction
participant stoichiometry: Compound/PW C108770 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108716 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108769 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134 Cytoplasm/Stoichiometry/1.0
right: Succinate
right: Carbon dioxide
right: Water
right: Deacetoxycephalosporin C
spontaneous: false
left: Oxygen
left: Oxoglutaric acid
left: Penicillin N
name: Oxoglutaric acid + Oxygen + Penicillin N ↔ Deacetoxycephalosporin C + Carbon dioxide + Succinate + Water
conversion direction: REVERSIBLE

Reaction212638
type: BiochemicalReaction
participant stoichiometry: Compound/PW C108770 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108771 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108716 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134 Cytoplasm/Stoichiometry/1.0
right: Succinate
right: Carbon dioxide
right: Deacetylcephalosporin C
spontaneous: false
left: Oxygen
left: Oxoglutaric acid
left: Deacetoxycephalosporin C
name: Deacetoxycephalosporin C + Oxoglutaric acid + Oxygen ↔ Carbon dioxide + Deacetylcephalosporin C + Succinate
conversion direction: REVERSIBLE

Reference/KEGG Compound C00097
type: UnificationXref
id: C00097
db: KEGG Compound

Deacetoxycephalosporin C synthase
type: Protein
cellular location: Cytoplasm
entity reference: Deacetoxycephalosporin C synthase

Acetic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Acetic acid

7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C
type: SmallMolecule
cellular location: Cytoplasm
entity reference: 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C

ChemicalStructure/PW C000749
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 25246222
type: UnificationXref
id: 25246222
db: PubChem-compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Compound/PW C108780 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cephalosporin C
stoichiometric coefficient: 1.0

2.1.3.7
type: BiochemicalReaction
participant stoichiometry: Compound/PW C108771 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108772 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000862 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001441 Cytoplasm/Stoichiometry/1.0
right: O-Carbamoyl-deacetylcephalosporin C
right: Phosphoric acid
spontaneous: false
EC number: 2.1.3.7
left: Deacetylcephalosporin C
left: Carbamoyl phosphate
name: Carbamoyl phosphate + Deacetylcephalosporin C ↔ O-Carbamoyl-deacetylcephalosporin C + Phosphoric acid
conversion direction: REVERSIBLE

Penicillin
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00395

Penicilloic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C06567

Reaction212642
type: BiochemicalReaction
participant stoichiometry: Compound/PW C108768 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/Generic592 Cytoplasm/Stoichiometry/1.0
right: Penicillin
spontaneous: false
left: Isopenicillin N
name: Isopenicillin N ↔ Penicillin
conversion direction: REVERSIBLE

Reaction212643
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/Generic592 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/Generic593 Cytoplasm/Stoichiometry/1.0
right: Penicilloic acid
spontaneous: false
left: Water
left: Penicillin
name: Penicillin + Water ↔ Penicilloic acid
conversion direction: REVERSIBLE

3.5.1.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108775 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/Generic71 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/Generic592 Cytoplasm/Stoichiometry/1.0
right: 6-Aminopenicillanic acid
right: Carboxylate
spontaneous: false
EC number: 3.5.1.11
left: Water
left: Penicillin
name: Penicillin + Water ↔ 6-Aminopenicillanic acid + Carboxylate
conversion direction: REVERSIBLE

Reaction212645
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000029 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108771 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108780 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
right: Water
right: Cephalosporin C
spontaneous: false
left: Deacetylcephalosporin C
left: Acetic acid
name: Acetic acid + Deacetylcephalosporin C ↔ Cephalosporin C + Water
conversion direction: REVERSIBLE

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

ReactionCatalysis202267
type: Catalysis
controller: CefF protein
controlled: Reaction212638
control type: ACTIVATION

Reference/ChEBI CHEBI 18065
type: UnificationXref
id: CHEBI:18065
db: ChEBI

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

ReactionCatalysis202268
type: Catalysis
controller: 3'-hydroxymethylcephem-O-carbamoyltransferase
controlled: 2.1.3.7
control type: ACTIVATION

ReactionCatalysis202269
type: Catalysis
controller: CmcI hydroxylase
controlled: Reaction212641
control type: ACTIVATION

Reference/ChEBI CHEBI 16680
type: UnificationXref
id: CHEBI:16680
db: ChEBI

Compound/PW C108767 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine
stoichiometric coefficient: 1.0

ReactionCatalysis202263
type: Catalysis
controller: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
controlled: Reaction212634
control type: ACTIVATION

ReactionCatalysis202264
type: Catalysis
controller: Isopenicillin N synthase
controlled: Reaction212635
control type: ACTIVATION

ReactionCatalysis202265
type: Catalysis
controller: Isopenicillin N epimerase
controlled: Reaction212636
control type: ACTIVATION

Reaction212640
type: BiochemicalReaction
participant stoichiometry: Compound/PW C108772 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108716 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108773 Cytoplasm/Stoichiometry/1.0
right: Succinate
right: Carbon dioxide
right: 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C
spontaneous: false
left: O-Carbamoyl-deacetylcephalosporin C
left: Oxygen
left: Oxoglutaric acid
name: O-Carbamoyl-deacetylcephalosporin C + Oxoglutaric acid + Oxygen ↔ 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + Carbon dioxide + Succinate
conversion direction: REVERSIBLE

ReactionCatalysis202266
type: Catalysis
controller: Deacetoxycephalosporin C synthase
controlled: Reaction212637
control type: ACTIVATION

Reaction212641
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000749 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108774 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108773 Cytoplasm/Stoichiometry/1.0
right: Cephamycin C
right: S-Adenosylhomocysteine
spontaneous: false
left: S-Adenosylmethionine
left: 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C
name: 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin C + S-Adenosylmethionine ↔ Cephamycin C + S-Adenosylhomocysteine
conversion direction: REVERSIBLE

Reference/PubChem-compound 176
type: UnificationXref
id: 176
db: PubChem-compound

Cephalosporin C
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Cephalosporin C

Reference/UniProt F8JTW2
type: UnificationXref
id: F8JTW2
db: UniProt

Reference/PubChem-compound 24762165
type: UnificationXref
id: 24762165
db: PubChem-compound

Reference/UniProt F8JTW4
type: UnificationXref
id: F8JTW4
db: UniProt

Unknown
type: Protein
cellular location: Cytoplasm
entity reference: Unknown

Reference/HMDB HMDB0000883
type: UnificationXref
id: HMDB0000883
db: HMDB

Compound/PW C000448 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Cysteine
stoichiometric coefficient: 1.0

S-Adenosylmethionine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: S-Adenosylmethionine

Reference/UniProt F8JTW5
type: UnificationXref
id: F8JTW5
db: UniProt

Reference/ChEBI CHEBI 29067
type: UnificationXref
id: CHEBI:29067
db: ChEBI

Reference/UniProt F8JTW8
type: UnificationXref
id: F8JTW8
db: UniProt

Reference/HMDB HMDB0002142
type: UnificationXref
id: HMDB0002142
db: HMDB

Reference/UniProt F8JTW7
type: UnificationXref
id: F8JTW7
db: UniProt

Succinate
type: SmallMoleculeReference
xref: Reference/CAS 110-15-6
xref: Reference/ChEBI CHEBI 15741
xref: Reference/PubChem-compound 3344
chemical formula: C4H6O4
molecular weight: 118.02661
structure: ChemicalStructure/PW C108716