L-Histidine + L-Tryptophan ↔ Histidyltryptophyldiketopiperazine
Histidyltryptophyldiketopiperazine ↔ Dehydrohistidyltryptophyldiketopiperazine
Dehydrohistidyltryptophyldiketopiperazine + Dimethylallylpyrophosphate ↔ Roquefortine C + diphosphate
Dimethylallylpyrophosphate + Histidyltryptophyldiketopiperazine ↔ Pyrophosphate + Roquefortine D
2 Oxygen + Roquefortine C + 2 [Reduced NADPH---hemoprotein reductase] ↔ Glandicoline A + 3 Water + 2 [Oxidized NADPH---hemoprotein reductase]
Oxygen + Roquefortine C + [Reduced NADPH---hemoprotein reductase] ↔ N1-Hydroxy-roquefortine C + Water + [Oxidized NADPH---hemoprotein reductase]
Glandicoline A + Oxygen + [Reduced NADPH---hemoprotein reductase] ↔ Glandicoline B + Water + [Oxidized NADPH---hemoprotein reductase]
Glandicoline B + S-Adenosylmethionine ↔ Meleagrin + S-Adenosylhomocysteine
N1-Hydroxy-roquefortine C + Oxygen + [Reduced NADPH---hemoprotein reductase] ↔ Roquefortine L + 2 Water + [Oxidized NADPH---hemoprotein reductase]
Oxygen + Roquefortine L + [Reduced NADPH---hemoprotein reductase] ↔ Glandicoline B + Water + [Oxidized NADPH---hemoprotein reductase]
N1-Hydroxy-roquefortine C + S-Adenosylmethionine ↔ Roquefortine F + S-Adenosylhomocysteine
Oxygen + Roquefortine F + [Reduced NADPH---hemoprotein reductase] ↔ Neoxaline + Water + [Oxidized NADPH---hemoprotein reductase]
[Oxidized NADPH---hemoprotein reductase]