Ascorbic acid + Dopamine + Oxygen → Dehydroascorbic acid + Norepinephrine + Water
L-Dopa + Oxygen + Tetrahydrobiopterin → 4a-Hydroxytetrahydrobiopterin + Dopamine
Sodium-dependent noradrenaline transporter
Phenylalanine, Tyrosine and Tryptophan Biosynthesis
L-Tryptophan + Oxygen + Tetrahydrobiopterin → 4a-Hydroxytetrahydrobiopterin + 5-Hydroxy-L-tryptophan
5-Hydroxy-L-tryptophan → Carbon dioxide + Serotonin
L-Tyrosine + Oxygen + Sapropterin → Dihydrobiopterin + L-Dopa + Water
Norepinephrine activates Alpha-1A adrenergic receptor
Norepinephrine activates Beta-1 adrenergic receptor
Clomipramine Mechanism of Action Action Pathway
Clomipramine inhibits Sodium-dependent serotonin transporter
Serotonin activates 5-hydroxytryptamine receptor 2C
Serotonin activates 5-hydroxytryptamine receptor 2A
Serotonin activates 5-hydroxytryptamine receptor 2B
Clomipramine inhibits Sodium-dependent noradrenaline transporter
Norepinephrine (→), Sodium (→) Transport: Homo sapiens, Neuron, Extracellular Space to Homo sapiens, Neuron, Cytosol
Serotonin (→), Sodium (→) Transport: Homo sapiens, Neuron, Extracellular Space to Homo sapiens, Neuron, Cytosol
Serotonin (→) Transport: Homo sapiens, Brain, Cell, Cytoplasm to Homo sapiens, Cell, Exocytic Vesicle
Serotonin (→) Transport: Homo sapiens, Cell, Exocytic Vesicle to Homo sapiens, Neuron, Extracellular Space
Norepinephrine (→) Transport: Homo sapiens, Cell, Exocytic Vesicle to Homo sapiens, Neuron, Extracellular Space
Dopamine (→) Transport: Homo sapiens, Brain, Cell, Cytoplasm to Homo sapiens, Cell, Exocytic Vesicle