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Protein URA2 Protein URA2 Protein URA2 aspartate transcarbamylase Dihydroorotase orotidine-5'- phosphate decarboxylase UMP kinase nucleoside diphosphate kinase CTP synthase ribonucleoside diphosphate reductase 1 Ribonucleoside- diphosphate reductase large chain 1 ribonucleoside diphosphate reductase 1 ribonucleoside diphosphate reductase 1 nucleoside diphosphate kinase deoxyuridine triphosphatase nucleoside triphosphate pyrophosphohydrolase pyrimidine deoxynucleoside triphosphate pyrophosphohydrolase nucleoside diphosphate kinase ribonucleoside- triphosphate reductase dihydroorotate dehydrogenase, type 2 Thymidylate synthase Orotate phosphoribosyltransferase 2 ribonucleoside- diphosphate reductase 2 ribonucleoside- diphosphate reductase 2 nucleoside diphosphate kinase ribonucleoside- triphosphate reductase dCTP deaminase Ribonucleoside- diphosphate reductase large chain 1 Ribonucleoside- diphosphate reductase small chain 2 Thymidylate kinase L-Glutamine Phosphoribosyl pyrophosphate HCO3- H2O ATP ADP Pi L-Glutamic acid H+ Carbamoyl phosphate L-Aspartic acid Pi H+ N-carbamoyl-L- aspartate H+ H2O 4,5-Dihydroorotic acid Orotidylic acid H+ CO2 Uridine 5'-monophosphate ATP ADP Uridine 5'-diphosphate ATP Uridine triphosphate ADP L-Glutamine H2O ATP ADP H+ Pi L-Glutamic acid Cytidine triphosphate H2O Pi H+ CDP H2O dCDP H2O dUDP ATP ADP Deoxyuridine triphosphate H2O Pi H+ dUMP ATP dTDP ADP Thymidine 5'-triphosphate H2O dCTP Ubiquinone-1 Ubiquinol-1 Orotic acid 5,10- methenyltetrahydrofolate mono-L-glutamate Dihydrofolic acid 5-Thymidylic acid PPi H2O ATP ADP H2O H2O H+ Ammonium H2O ATP ADP Adenosine triphosphate Zinc Magnesium Magnesium Adenosine triphosphate Fe2+ Magnesium Magnesium Zinc Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Flavin Mononucleotide Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S Fe3+ reduced thioredoxin oxidized thioredoxin reduced thioredoxin oxidized thioredoxin a reduced flavodoxin an oxidized flavodoxin an oxidized NrdH glutaredoxin- like protein a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein L-Glutamate Metabolism PRPP Biosynthesis a reduced NrdH glutaredoxin- like protein Guanosine triphosphate Magnesium
URA2 URA2 URA2 Unknown URA4 Unknown Unknown Unknown Unknown Unknown RNR1 Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown CDC21 URA10 Unknown Unknown Unknown Unknown Unknown RNR1 RNR4 CDC8 L-Glutamine Phosphoribosyl pyrophosphate Hydrogen carbonate Water Adenosine triphosphate Adenosine diphosphate Phosphate L-Glutamic acid Hydrogen Ion Carbamoyl phosphate L-Aspartic acid Phosphate Hydrogen Ion N-carbamoyl-L- aspartate Hydrogen Ion Water 4,5-Dihydroorotic acid Orotidylic acid Hydrogen Ion Carbon dioxide Uridine 5'-monophosphate Adenosine triphosphate Adenosine diphosphate Uridine 5'-diphosphate Adenosine triphosphate Uridine triphosphate Adenosine diphosphate L-Glutamine Water Adenosine triphosphate Adenosine diphosphate Hydrogen Ion Phosphate L-Glutamic acid Cytidine triphosphate Water Phosphate Hydrogen Ion CDP Water dCDP Water dUDP Adenosine triphosphate Adenosine diphosphate Deoxyuridine triphosphate Water Phosphate Hydrogen Ion dUMP Adenosine triphosphate dTDP Adenosine diphosphate Thymidine 5'-triphosphate Water dCTP Ubiquinone-1 Ubiquinol-1 Orotic acid 5,10- methenyltetrahydrofolate mono-L-glutamate Dihydrofolic acid 5-Thymidylic acid Pyrophosphate Water Adenosine triphosphate Adenosine diphosphate Water Water Hydrogen Ion Ammonium Water Adenosine triphosphate Adenosine diphosphate reduced thioredoxin oxidized thioredoxin reduced thioredoxin oxidized thioredoxin a reduced flavodoxin an oxidized flavodoxin an oxidized NrdH glutaredoxin-like protein a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin-like protein an oxidized NrdH glutaredoxin-like protein L-Glutamate Metabolism PRPP Biosynthesis a reduced NrdH glutaredoxin-like protein