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Dihydropyrimidine dehydrogenase [NADP(+)] Dihydropyrimidinase Beta- ureidopropionase Alanine aminotransferase 1 Thymine NADP Dihydrothymine NADPH H2O Ureidoisobutyric acid H2O 3-Aminoisobutanoic acid CO2 NH3 (S)-Methylmalonic acid semialdehyde FAD Flavin Mononucleotide Zinc (II) ion Zinc (II) ion Pyridoxal 5'-phosphate Espacio intracelular Espació extracelular