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Hexoquinasa G=-16.7 kJ/mol NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 Cytochrome b-c1 complex subunit Rieske, mitochondrial Cytochrome c oxidase subunit 6B2 ATP-binding cassette sub-family A member 1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 Cytochrome b-c1 complex subunit Rieske, mitochondrial Cytochrome c1, heme protein, mitochondrial D-Glucose Glucose 6-phosphate Fructose 6-phosphate Fructose 1,6- bisphosphate Fructose 6-phosphate Glucose 6-phosphate Fructose 1,6- bisphosphate D- Glyceraldehyde 3-phosphate Dihydroxyacetone phosphate Dihydroxyacetone phosphate D- Glyceraldehyde 3-phosphate D- Glyceraldehyde 3-phosphate NAD Glyceric acid 1,3-biphosphate Pi NADH Glyceric acid 1,3-biphosphate 3- Phosphoglyceric acid 3- Phosphoglyceric acid 2- Phosphoglyceric acid 2- Phosphoglyceric acid Phosphoenolpyruvic acid ATP Pyruvic acid ADP Phosphoenolpyruvic acid ATP ADP ATP ADP ADP ATP Pyruvic acid Acetaldehyde Acetaldehyde H+ NADH Ethanol NAD β-D-Glucose 6-phosphate NADP 6- Phosphonoglucono- D-lactone NADPH Hydrogen Ion 6- Phosphonoglucono- D-lactone H2O 6- Phosphogluconic acid H+ 6- Phosphogluconic acid NADP D-Ribulose 5-phosphate CO2 NADPH Xylulose 5-phosphate D-Sedoheptulose 7-phosphate D-Ribulose 5-phosphate Xylulose 5-phosphate D-Ribose 5-phosphate D-Ribose 5-phosphate D- Glyceraldehyde 3-phosphate D-Erythrose 4-phosphate Fructose 6-phosphate D-Erythrose 4-phosphate Fructose 6-phosphate D- Glyceraldehyde 3-phosphate Maltose D-Glucose Sucrose D-Glucose D-Fructose α-Lactose D-Glucose D-Galactose D-Fructose Fructose 6-phosphate Fructose 1-phosphate Fructose 1-phosphate Dihydroxyacetone phosphate Glyceraldehyde Dihydroxyacetone phosphate Glyceraldehyde D- Glyceraldehyde 3-phosphate Galactose 1-phosphate Uridine diphosphategalactose Uridine diphosphate glucose Glucose 1-phosphate Glucose 6-phosphate Glycogen D-Mannose Mannose 6-phosphate Fructose 6-phosphate Acetyl-CoA D-Ribose 5-phosphate ATP Phosphoribosyl pyrophosphate AMP Glucose 1-phosphate Uridine diphosphate glucose PPi Uridine triphosphate Glycogen Oxaloacetate H2O Citric acid CoA cis-Aconitic acid H2O H2O Isocitric acid NAD Oxoglutaric acid NADH H+ NAD CoA Succinyl-CoA CO2 NADH H+ GDP Pi Succinic acid GTP CoA FAD Fumaric acid FADH2 H2O L-Malic acid NAD Oxalacetic acid NADH H+ ADP Phosphorus ATP NAD H+ NADH FADH2 FAD H+ Glucose 1-phosphate Glycogen Glucose 6-phosphate Oxalacetic acid Malic acid H+ NADH NAD Malic acid NAD NADH H+ Oxaloacetate Oxaloacetate L-Aspartic acid L-Glutamic acid A-Ketoglutaric acid oxime L-Glutamic acid A-Ketoglutaric acid oxime NAD NADH H+ Glycerol 3-phosphate Dihydroxyacetone phosphate FAD FADH2 ATP PPi H2O Urea ATP ADP Pi H2O L-Glutamine 5- Phosphoribosylamine PPi L-Glutamic acid Glycine ATP Glycineamideribotide ADP Pi L-Glutamine ATP L-Glutamic acid ADP Pi ATP ADP Pi ATP L-Aspartic acid ADP Pi L-Aspartic acid GTP GDP Pi ATP H2O HCO3- ADP Pi L-Glutamic acid L-Aspartic acid Pi H2O Pi H2O NH3 H2O D-Ribose H2O Superoxide H2O2 H2O Superoxide H2O2 NADP NADPH H+ HCO3- Ammonium H2O FAD FADH2 NADH H+ NAD H2O CO2 L-Lactic acid Q H2O O2 H+ H+ Q O2 H2O H+ H+ H+ H+ Oxalacetic acid L-Aspartic acid Q Acetoacetyl-CoA D-Erythrose 4-phosphate Ammonium Pi AMP CO2 H2O Fumaric acid H2O H2O Uridine diphosphategalactose Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial ACP Fosofohexosa isomerasa G=1.7 kJ/mol Fosfofructocinasa G=-14.2 kJ/mol Aldolasa G=23.8 kJ/mol Triosa Fosfato Isomerasa Gliceraldehído 3-fofato deshidrogenasa G=6.3kJ/mol Fosfoglicerato cinasa G=-18.5 kJ/mol Fosfogliceromutasa G=4.4kJ/mol Enolasa G=7.5 kJ/mol Piruvato Cinasa G=-31.4 kJ/mol Piruvato descarboxilasa Alcohol deshidrogenasa Lactato deshidrogenasa Glucosa 6-fosfato deshidrogenasa Lactonasa 6-Fosfogluconato deshidrogenasa Ribulosa 5-fosfato 3-epimerasa Ribulosa 5-fofato isomerasa Transcetolasa Transaldolasa Transcetolasa UDP UDP Glucosa Galactosa 1-fosfato Uridil transferasa Sacarasa Hexoquinasa Fructoquinasa Fructosa 1-fosfato aldolasa Triosa quinasa Triosa fosfato isomerasa Lactasa Galactoquinasa Fosforilasa Fosfomanosa isomerasa Hexoquinasa Fosfoglucomutasa UDP-Galactosa epimerasa UDP-Glucosa Galactosa 1-fosfato Uridil transfersa Maltasa Histidina Fosforribosilpirofosfato sintetasa UDP-Glucosa pirofosforilasa Glucogeno sintasa UDP MATRIZ MEMBRANA INTERNA Piruvato carboxilasa PEP Carboxicinasa Fructosa 1,6 bifosfatasa Glucosa 6 fosfatasa Glucógeno fosforilasa Glucano transferasa-Enzima desramificadora Fosfoglucomutasa Glucosa 6 fosfatasa (em higado) Transportador malato alfa-cetoglutarato Transportador glutamato-aspartato Complejo de glicerol 3 fosfato deshidrogenasa Ciclo de krebs, Beta-Oxidación Glucolisis Citrato sintasa Aconitasa Isocitrato Deshidrogenasa Cetoglutarato deshidrogenasa Succinil-CoA sintetasa Succinato deshidrogenasa Fumarasa Malato Deshidrogenasa Malato Deshidrogenasa Aspartato aminotransferasa Malato deshidrogenasa Aspartato aminotransferasa Glicerol 3-fosfato deshidrogenasa Alanina, Cisteína, Glicina, Serina, Treonina, Triptófano Alanina, Valina, Leucina, Isoleucina Isoleucina, Leucina, Triptofano Leucina, Lisina, Fenilalanina, Triptófano, Tirosina Arginina, Glutamato, Glutamina, Histidina, Prolina Isoleucina, Metionina, Treonina, Valina Aspartato, Fenilalanina, Tirosina Asparagina, Aspartato Serina Glicina, Cisteína Triptófano, Fenilalanina, Tirosina Glutamato Glutamina, Prolina, Arginina Aspartato Asparagina, Metionina, Treonina, Lisina Ornitina Glutamato Citrulina Carbamoil fosfato Ornitina Glutamina Aspartato Oxalacetato Alfa-Cetoglutarato Glutamato Aminoácido Acil-CoA -2C trans-enoil-CoA S-3-Hidroxiacil-CoA Fumarato Aspartato Urea Arginina Argininosuccinato Citrulina 3-cetoacil-CoA Acetil-CoA CoASH Oxalacetato Piruvato Citrato Piruvato Citrato Transportador de Piruvato Transportador de Tricarboxilo Malato Oxalacetato Acetil-CoA Acetil-CoA Palmitato Palmitoyl-S-ACP Acyl-S-ACP Butiril-ACP Trans-Enoil-ACP D-3-Hidroxiacil-ACP Beta-Cetoacil-ACP Acetil-ACP Glutaminasa Glutamato deshidrogenasa Aspartato aminotransferasa Carbamoil fosfato sintetasa I FGAR FGAM Carbamoilo aspartato Carbamoilfosfato IMP SAICAR Glutamina AICAR FAICAR Adenilosuccinato Fumarato AMP CAIR AIR Timina Ácido orótico UMP Carbamoil fosfato sintetasa II Inosina Uracilo Acido Urico Xantina Hipoxantina Adenosina Nucleosidasa Xantina oxidasa Xantina oxidasa Adenosina desaminasa 5-nucleotidasa Acetil-CoA Succinil-CoA Beta-Alanina Beta-Aminoisobutirato Ureidopropionato Ureidoisobutirato Dihidrotimina Dihidrouracilo Ureidopropionasa Dihidropirimidinasa Dihisrouracilo deshidrogenasa Enoil-ACP reductasa 3-hidroxiacil-ACP deshidratasa Cetoacetil-ACP reductasa Cetoacetil-ACP sintasa Hidrolisis CICLO 3-7 CICLO 2 Tiolasa Hidroxiacil-CoA deshidrogenasa Enoil-CoA hidratasa Acil-CoA deshidrogenasa Arginasa Argino succinasa Argino succin sintetasa Ornitina Transcarbamilasa SAICAR Sintetasa IMP Ciclohidrolasa Adenilosuccinatoliasa AICAR Transformilasa AIR Carboxilasa AIR sintetasa FGAM sintetasa GAR Transformilasa GAR Sintetasa Glutamina-PRPP amidotransferasa Adenilosuccinato sintetasa
Mitochondria NDUFA8 UQCRFS1 COX6B2 ABCA1 NDUFA8 UQCRFS1 CYC1 D-Glucose Glucose 6-phosphate Fructose 6-phosphate Fructose 1,6- bisphosphate Fructose 6-phosphate Glucose 6-phosphate Fructose 1,6- bisphosphate D- Glyceraldehyde 3-phosphate Dihydroxyacetone phosphate Dihydroxyacetone phosphate D- Glyceraldehyde 3-phosphate D- Glyceraldehyde 3-phosphate NAD Glyceric acid 1,3-biphosphate Phosphate NADH Glyceric acid 1,3-biphosphate 3- Phosphoglyceric acid 3- Phosphoglyceric acid 2- Phosphoglyceric acid 2- Phosphoglyceric acid Phosphoenolpyruvic acid Adenosine triphosphate Pyruvic acid Adenosine diphosphate Phosphoenolpyruvic acid Adenosine triphosphate Adenosine diphosphate Adenosine triphosphate Adenosine diphosphate Adenosine diphosphate Adenosine triphosphate Pyruvic acid Acetaldehyde Acetaldehyde Hydrogen Ion NADH Ethanol NAD β-D-Glucose 6-phosphate NADP 6- Phosphonoglucono- D-lactone NADPH 6- Phosphonoglucono- D-lactone Water 6- Phosphogluconic acid Hydrogen 6- Phosphogluconic acid NADP D-Ribulose 5-phosphate Carbon dioxide NADPH Xylulose 5-phosphate D-Sedoheptulose 7-phosphate D-Ribulose 5-phosphate Xylulose 5-phosphate D-Ribose 5-phosphate D-Ribose 5-phosphate D- Glyceraldehyde 3-phosphate D-Erythrose 4-phosphate Fructose 6-phosphate D-Erythrose 4-phosphate Fructose 6-phosphate D- Glyceraldehyde 3-phosphate Maltose D-Glucose Sucrose D-Glucose D-Fructose α-Lactose D-Glucose D-Galactose D-Fructose Fructose 6-phosphate Fructose 1-phosphate Fructose 1-phosphate Dihydroxyacetone phosphate Glyceraldehyde Dihydroxyacetone phosphate Glyceraldehyde D- Glyceraldehyde 3-phosphate Galactose 1-phosphate Uridine diphosphategalactose Uridine diphosphate glucose Glucose 1-phosphate Glucose 6-phosphate Glycogen D-Mannose Mannose 6-phosphate Fructose 6-phosphate Acetyl-CoA D-Ribose 5-phosphate Adenosine triphosphate Phosphoribosyl pyrophosphate Adenosine monophosphate Glucose 1-phosphate Uridine diphosphate glucose Pyrophosphate Glycogen Oxaloacetate Water Citric acid Coenzyme A cis-Aconitic acid Water Water Isocitric acid NAD Oxoglutaric acid NADH Hydrogen NAD Coenzyme A Succinyl-CoA Carbon dioxide NADH Hydrogen Guanosine diphosphate Phosphate Succinic acid Guanosine triphosphate Coenzyme A FAD Fumaric acid Water L-Malic acid NAD Oxalacetic acid NADH Hydrogen Adenosine diphosphate Adenosine triphosphate NAD Hydrogen NADH FAD Hydrogen Glucose 1-phosphate Glycogen Glucose 6-phosphate Oxalacetic acid Malic acid Hydrogen NADH NAD Malic acid NAD NADH Hydrogen Oxaloacetate Oxaloacetate L-Aspartic acid L-Glutamic acid A-Ketoglutaric acid oxime L-Glutamic acid A-Ketoglutaric acid oxime NAD NADH Hydrogen Glycerol 3-phosphate Dihydroxyacetone phosphate FAD Adenosine triphosphate Pyrophosphate Water Adenosine triphosphate Adenosine diphosphate Phosphate Water Pyrophosphate Adenosine triphosphate Adenosine diphosphate Phosphate Adenosine triphosphate Adenosine diphosphate Phosphate Adenosine triphosphate Adenosine diphosphate Phosphate Adenosine triphosphate Adenosine diphosphate Phosphate Guanosine triphosphate Guanosine diphosphate Phosphate Adenosine triphosphate Water Hydrogen carbonate Adenosine diphosphate Phosphate Phosphate Water Phosphate Water Ammonia Water Water Hydrogen peroxide Water Hydrogen peroxide NADP NADPH Hydrogen Hydrogen carbonate Water FAD NADH Hydrogen NAD Water Carbon dioxide L-Lactic acid Coenzyme Q10 Water Oxygen Hydrogen Hydrogen Coenzyme Q10 Oxygen Water Hydrogen Hydrogen Hydrogen Hydrogen Oxalacetic acid L-Aspartic acid Coenzyme Q10 Acetoacetyl-CoA D-Erythrose 4-phosphate Phosphate Adenosine monophosphate Carbon dioxide Water Water Water SDHD
Hexoquinasa G=-16.7 kJ/mol NDUFA8 UQCRFS1 COX6B2 ABCA1 NDUFA8 UQCRFS1 CYC1 D-Glc Gluc-6P Fru6P Fru1,6P Fru6P Gluc-6P Fru1,6P Glyc3P Dhapp Dhapp Glyc3P Glyc3P NAD GlyABp Pi NADH GlyABp G3P G3P 2-PPGA 2-PPGA Pep ATP Pyr ADP Pep ATP ADP ATP ADP ADP ATP Pyr Ethanal Ethanal H+ NADH Ethanol NAD BDGlu6P NADP 6-PGDL NADPH H+ 6-PGDL H2O 6-PPGA H+ 6-PPGA NADP RP CO2 NADPH Xyl-5-P D-SH7P RP Xyl-5-P DRib-5P DRib-5P Glyc3P D-Ery4P Fru6P D-Ery4P Fru6P Glyc3P Maltose D-Glc Sucrose D-Glc Fru Lactin D-Glc D-Gal Fru Fru6P Fru-1P Fru-1P Dhapp Glycald Dhapp Glycald Glyc3P G1P UDPPG UDPG Gluc1P Gluc-6P Glycogn Man Man-6P Fru6P Ac-CoA DRib-5P ATP PRPP AMP Gluc1P UDPG PPi UTP Glycogn Oxalo H2O CA CoA Aconiti H2O H2O I-cita NAD AKG NADH H+ NAD CoA Suc-CoA CO2 NADH H+ GDP Pi Succini GTP CoA FAD Fumarat FADH2 H2O Malate NAD Oaa NADH H+ ADP P ATP NAD H+ NADH FADH2 FAD H+ Gluc1P Glycogn Gluc-6P Oaa Malate H+ NADH NAD Malate NAD NADH H+ Oxalo Oxalo Asp Glu AKAO Glu AKAO NAD NADH H+ Glyc1P Dhapp FAD FADH2 ATP PPi H2O Urea ATP ADP Pi H2O Gln 5-PPRSA PPi Glu Gly ATP Glyadbt ADP Pi Gln ATP Glu ADP Pi ATP ADP Pi ATP Asp ADP Pi Asp GTP GDP Pi ATP H2O HCO3- ADP Pi Glu Asp Pi H2O Pi H2O NH3 H2O Ribose H2O O2(-) H2O2 H2O O2(-) H2O2 NADP NADPH H+ HCO3- Ammon H2O FAD FADH2 NADH H+ NAD H2O CO2 Lactate Q H2O O2 H+ H+ Q O2 H2O H+ H+ H+ H+ Oaa Asp Q ActaCoA D-Ery4P Ammon Pi AMP CO2 H2O Fumarat H2O H2O UDPPG SDHD ACP Fosofohexosa isomerasa G=1.7 kJ/mol Fosfofructocinasa G=-14.2 kJ/mol Aldolasa G=23.8 kJ/mol Triosa Fosfato Isomerasa Gliceraldehído 3-fofato deshidrogenasa G=6.3kJ/mol Fosfoglicerato cinasa G=-18.5 kJ/mol Fosfogliceromutasa G=4.4kJ/mol Enolasa G=7.5 kJ/mol Piruvato Cinasa G=-31.4 kJ/mol Piruvato descarboxilasa Alcohol deshidrogenasa Lactato deshidrogenasa Glucosa 6-fosfato deshidrogenasa Lactonasa 6-Fosfogluconato deshidrogenasa Ribulosa 5-fosfato 3-epimerasa Ribulosa 5-fofato isomerasa Transcetolasa Transaldolasa Transcetolasa UDP UDP Glucosa Galactosa 1-fosfato Uridil transferasa Sacarasa Hexoquinasa Fructoquinasa Fructosa 1-fosfato aldolasa Triosa quinasa Triosa fosfato isomerasa Lactasa Galactoquinasa Fosforilasa Fosfomanosa isomerasa Hexoquinasa Fosfoglucomutasa UDP-Galactosa epimerasa UDP-Glucosa Galactosa 1-fosfato Uridil transfersa Maltasa Histidina Fosforribosilpirofosfato sintetasa UDP-Glucosa pirofosforilasa Glucogeno sintasa UDP MATRIZ MEMBRANA INTERNA Piruvato carboxilasa PEP Carboxicinasa Fructosa 1,6 bifosfatasa Glucosa 6 fosfatasa Glucógeno fosforilasa Glucano transferasa-Enzima desramificadora Fosfoglucomutasa Glucosa 6 fosfatasa (em higado) Transportador malato alfa-cetoglutarato Transportador glutamato-aspartato Complejo de glicerol 3 fosfato deshidrogenasa Ciclo de krebs, Beta-Oxidación Glucolisis Citrato sintasa Aconitasa Isocitrato Deshidrogenasa Cetoglutarato deshidrogenasa Succinil-CoA sintetasa Succinato deshidrogenasa Fumarasa Malato Deshidrogenasa Malato Deshidrogenasa Aspartato aminotransferasa Malato deshidrogenasa Aspartato aminotransferasa Glicerol 3-fosfato deshidrogenasa Alanina, Cisteína, Glicina, Serina, Treonina, Triptófano Alanina, Valina, Leucina, Isoleucina Isoleucina, Leucina, Triptofano Leucina, Lisina, Fenilalanina, Triptófano, Tirosina Arginina, Glutamato, Glutamina, Histidina, Prolina Isoleucina, Metionina, Treonina, Valina Aspartato, Fenilalanina, Tirosina Asparagina, Aspartato Serina Glicina, Cisteína Triptófano, Fenilalanina, Tirosina Glutamato Glutamina, Prolina, Arginina Aspartato Asparagina, Metionina, Treonina, Lisina Ornitina Glutamato Citrulina Carbamoil fosfato Ornitina Glutamina Aspartato Oxalacetato Alfa-Cetoglutarato Glutamato Aminoácido Acil-CoA -2C trans-enoil-CoA S-3-Hidroxiacil-CoA Fumarato Aspartato Urea Arginina Argininosuccinato Citrulina 3-cetoacil-CoA Acetil-CoA CoASH Oxalacetato Piruvato Citrato Piruvato Citrato Transportador de Piruvato Transportador de Tricarboxilo Malato Oxalacetato Acetil-CoA Acetil-CoA Palmitato Palmitoyl-S-ACP Acyl-S-ACP Butiril-ACP Trans-Enoil-ACP D-3-Hidroxiacil-ACP Beta-Cetoacil-ACP Acetil-ACP Glutaminasa Glutamato deshidrogenasa Aspartato aminotransferasa Carbamoil fosfato sintetasa I FGAR FGAM Carbamoilo aspartato Carbamoilfosfato IMP SAICAR Glutamina AICAR FAICAR Adenilosuccinato Fumarato AMP CAIR AIR Timina Ácido orótico UMP Carbamoil fosfato sintetasa II Inosina Uracilo Acido Urico Xantina Hipoxantina Adenosina Nucleosidasa Xantina oxidasa Xantina oxidasa Adenosina desaminasa 5-nucleotidasa Acetil-CoA Succinil-CoA Beta-Alanina Beta-Aminoisobutirato Ureidopropionato Ureidoisobutirato Dihidrotimina Dihidrouracilo Ureidopropionasa Dihidropirimidinasa Dihisrouracilo deshidrogenasa Enoil-ACP reductasa 3-hidroxiacil-ACP deshidratasa Cetoacetil-ACP reductasa Cetoacetil-ACP sintasa Hidrolisis CICLO 3-7 CICLO 2 Tiolasa Hidroxiacil-CoA deshidrogenasa Enoil-CoA hidratasa Acil-CoA deshidrogenasa Arginasa Argino succinasa Argino succin sintetasa Ornitina Transcarbamilasa SAICAR Sintetasa IMP Ciclohidrolasa Adenilosuccinatoliasa AICAR Transformilasa AIR Carboxilasa AIR sintetasa FGAM sintetasa GAR Transformilasa GAR Sintetasa Glutamina-PRPP amidotransferasa Adenilosuccinato sintetasa
Mitochondria NDUFA8 UQCRFS1 COX6B2 ABCA1 NDUFA8 UQCRFS1 CYC1 D-Glc Gluc-6P Fru6P Fru1,6P Fru6P Gluc-6P Fru1,6P Glyc3P Dhapp Dhapp Glyc3P Glyc3P NAD GlyABp Pi NADH GlyABp G3P G3P 2-PPGA 2-PPGA Pep ATP Pyr ADP Pep ATP ADP ATP ADP ADP ATP Pyr Ethanal Ethanal H+ NADH Ethanol NAD BDGlu6P NADP 6-PGDL NADPH 6-PGDL H2O 6-PPGA H2 6-PPGA NADP RP CO2 NADPH Xyl-5-P D-SH7P RP Xyl-5-P DRib-5P DRib-5P Glyc3P D-Ery4P Fru6P D-Ery4P Fru6P Glyc3P Maltose D-Glc Sucrose D-Glc Fru Lactin D-Glc D-Gal Fru Fru6P Fru-1P Fru-1P Dhapp Glycald Dhapp Glycald Glyc3P G1P UDPPG UDPG Gluc1P Gluc-6P Glycogn Man Man-6P Fru6P Ac-CoA DRib-5P ATP PRPP AMP Gluc1P UDPG Ppi Glycogn Oxalo H2O CA CoA Aconiti H2O H2O I-cita NAD AKG NADH H2 NAD CoA Suc-CoA CO2 NADH H2 GDP Pi Succini GTP CoA FAD Fumarat H2O Malate NAD Oaa NADH H2 ADP ATP NAD H2 NADH FAD H2 Gluc1P Glycogn Gluc-6P Oaa Malate H2 NADH NAD Malate NAD NADH H2 Oxalo Oxalo Asp Glu AKAO Glu AKAO NAD NADH H2 Glyc1P Dhapp FAD ATP Ppi H2O ATP ADP Pi H2O Ppi ATP ADP Pi ATP ADP Pi ATP ADP Pi ATP ADP Pi GTP GDP Pi ATP H2O HCO3 ADP Pi Pi H2O Pi H2O NH3 H2O H2O H2O2 H2O H2O2 NADP NADPH H2 HCO3 H2O FAD NADH H2 NAD H2O CO2 Lactate Coq H2O O2 H2 H2 Coq O2 H2O H2 H2 H2 H2 Oaa Asp Coq ActaCoA D-Ery4P Pi AMP CO2 H2O H2O H2O SDHD