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Mitochondrial pyruvate carrier 1 Pyruvate dehydrogenase complex Citrate synthase 3 Homoisocitrate dehydrogenase, mitochondrial Isocitrate dehydrogenase Homoisocitrate dehydrogenase, mitochondrial Oxoglutarate dehydrogenase complex Succinyl-CoA ligase Fumarate hydratase, mitochondrial Acetyl-CoA carboxylase Succinate dehydrogenase 3- isopropylmalate dehydratase 3- isopropylmalate dehydratase Malate dehydrogenase, mitochondrial Pyruvic acid Oxalacetic acid Fumaric acid Succinic acid FADH2 Oxoglutaric acid Acetyl-CoA Pyruvic acid CoA NAD CO2 NADH H2O Citric acid CoA Isocitric acid NAD CO2 NADH H+ NAD CoA Succinyl-CoA NADH H+ CO2 Pi GDP CoA GTP L-Malic acid H2O ATP HCO3- ADP Pi Q FAD QH2 cis-Aconitic acid H2O H2O NADH H+ NAD Thiamine pyrophosphate Lipoamide FAD Magnesium Thiamine pyrophosphate Lipoamide FAD Biotin Manganese 4Fe-4S 4Fe-4S Gluconeogenesis Glycolysis Pyruvate Metabolism Alanine Metabolism Aspartate Metabolism Pyruvate Metabolism Aspartate Metabolism Tyrosine Metabolism Arginine and Proline Metabolism Urea Cycle Propanoate Metabolism Mitochondrial Electron Transport Chain Malate- Aspartate Shuttle Glutamate Metabolism Alanine Metabolism Gluconeogenesis Glucose-Alanine Cycle Valine, Leucine, and Isoleucine Degradation Tryptophan Metabolism Pyruvate Metabolism Fatty Acid Metabolism Ketone Body Metabolism Lysine Degradation Oxidation of Branched-Chain Fatty Acids Propanoate Metabolism Inner mitochondrial membrane Mitochondrial intermembrane space Mitochondrial matrix Inner mitochondrial membrane Outer mitochondrial membrane