Reference/KEGG Compound C07508
type: UnificationXref
id: C07508
db: KEGG Compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Stomach
type: TissueVocabulary
xref: Reference/BRENDA TISSUE ONTOLOGY BTO 0001307

ChemicalStructure/PW C000693
type: ChemicalStructure
structure format: SMILES
structure data: NCCC1=CNC=N1

direct_interaction
type: InteractionVocabulary

Reference/HMDB HMDB0000895
type: UnificationXref
id: HMDB0000895
db: HMDB

Reference/UniProt P00915
type: UnificationXref
id: P00915
db: UniProt

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

ChemicalStructure/PW C009148
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0014808
type: UnificationXref
id: HMDB0014808
db: HMDB

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/UniProt P20648
type: UnificationXref
id: P20648
db: UniProt

Compound/PW C000374 Basolateral cell membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chloride ion
stoichiometric coefficient: 1.0

Apical cell membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0016324

Acetylcholine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15355
xref: Reference/CAS 51-84-3
xref: Reference/HMDB HMDB0000895
xref: Reference/ChemSpider 182
xref: Reference/KEGG Compound C01996
xref: Reference/BioCyc ACETYLCHOLINE
xref: Reference/PubChem-compound 187
chemical formula: C7H16NO2
molecular weight: 146.1181
structure: ChemicalStructure/PW C000714

Reference/PathWhiz PW126191
type: UnificationXref
id: PW126191
db: PathWhiz

Histamine H2 receptor
type: Protein
entity reference: Histamine H2 receptor
name: SubPathwayInput

TransportCatalysis4844
type: Catalysis
controller: KCNE2/KCNQ1 Channel
controlled: Transport13806
control type: ACTIVATION

Muscarinic acetylcholine receptor M1
type: Protein
entity reference: Muscarinic acetylcholine receptor M1

ChemicalStructure/PW C000457
type: ChemicalStructure
structure format: SMILES
structure data: [K+]

ChemicalStructure/PW C000463
type: ChemicalStructure
structure format: SMILES
structure data: OC(O)=O

Muscarinic acetylcholine receptor M3
type: Protein
entity reference: Muscarinic acetylcholine receptor M3
name: SubPathwayInput

Reference/PathWhiz PW000728
type: UnificationXref
id: PW000728
db: PathWhiz

Chloride anion exchanger
type: ProteinReference
xref: Reference/UniProt P40879

Reference/BioCyc HCO3
type: UnificationXref
id: HCO3
db: BioCyc

TransportCatalysis2311
type: Catalysis
controller: H(+)/K(+) ATPase subunit
controlled: Transport11168
control type: ACTIVATION

Compound/PW C000457 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Potassium
stoichiometric coefficient: 1.0

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/KEGG Compound C00698
type: UnificationXref
id: C00698
db: KEGG Compound

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reference/UniProt P20309
type: UnificationXref
id: P20309
db: UniProt

Chloride ion
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17996
xref: Reference/BioCyc CPD-4521
xref: Reference/PubChem-compound 312
xref: Reference/KEGG Compound C00698
xref: Reference/HMDB HMDB0000492
xref: Reference/ChemSpider 306
xref: Reference/CAS 16887-00-6
chemical formula: Cl
molecular weight: 34.968853
structure: ChemicalStructure/PW C000374

Reference/BioCyc ACETYLCHOLINE
type: UnificationXref
id: ACETYLCHOLINE
db: BioCyc

Reference/UniProt P01350
type: UnificationXref
id: P01350
db: UniProt

Compound/PW C000463 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen carbonate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 813
type: UnificationXref
id: 813
db: PubChem-compound

Reference/HMDB HMDB0013072
type: UnificationXref
id: HMDB0013072
db: HMDB

Somatostatin receptor type 2
type: Protein
cellular location: Apical cell membrane
entity reference: Somatostatin receptor type 2

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Potassium-transporting ATPase subunit beta
type: ProteinReference
xref: Reference/UniProt P51164

SubPathwayInteraction116828
type: Interaction
name: SubPathwayReaction
name: SubPathway116828Reaction
participant: Histamine H2 receptor
participant: H(+)/K(+) ATPase subunit
participant: Muscarinic acetylcholine receptor M3
participant: Somatostatin receptor type 2
participant: Gastrin/cholecystokinin type B receptor

Reference/KEGG Compound C00238
type: UnificationXref
id: C00238
db: KEGG Compound

Compound/PW C040034 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/CAS 28797-61-7
type: UnificationXref
id: 28797-61-7
db: CAS

Potassium-transporting ATPase alpha chain 1
type: ProteinReference
xref: Reference/UniProt P20648

Somatostatin receptor type 2
type: Protein
entity reference: Somatostatin receptor type 2
name: SubPathwayInput

Potassium voltage-gated channel subfamily E member 2
type: Protein
entity reference: Potassium voltage-gated channel subfamily E member 2

ChemicalStructure/PW C000374
type: ChemicalStructure
structure format: SMILES
structure data: [Cl-]

Compound/PW C000463/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen carbonate
stoichiometric coefficient: 1.0

Potassium voltage-gated channel subfamily KQT member 1
type: Protein
entity reference: Potassium voltage-gated channel subfamily KQT member 1

Reference/PubChem-compound 4848
type: UnificationXref
id: 4848
db: PubChem-compound

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/SMPDB SMP0124706
type: UnificationXref
id: SMP0124706
db: SMPDB

TransportCatalysis2051
type: Catalysis
controller: Chloride anion exchanger
controlled: Transport10881
control type: ACTIVATION

Parietal Cell
type: CellVocabulary
xref: Reference/CELL TYPE ONTOLOGY CL 0000162

Muscarinic acetylcholine receptor M1
type: ProteinReference
xref: Reference/UniProt P11229
organism: BiologicalState778

Reference/PubChem-compound 312
type: UnificationXref
id: 312
db: PubChem-compound

Reference/UniProt P30874
type: UnificationXref
id: P30874
db: UniProt

ReactionCatalysis1409
type: Catalysis
controller: Carbonic anhydrase 1
controlled: 4.2.1.1
control type: ACTIVATION

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/CAS 24203-36-9
type: UnificationXref
id: 24203-36-9
db: CAS

Reference/ChEBI CHEBI 8247
type: UnificationXref
id: CHEBI:8247
db: ChEBI

Reference/HMDB HMDB0000586
type: UnificationXref
id: HMDB0000586
db: HMDB

Reference/UniProt P11229
type: UnificationXref
id: P11229
db: UniProt

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Gastrin
type: ProteinReference
xref: Reference/UniProt P01350
organism: BiologicalState777

Muscarinic acetylcholine receptor M3
type: ProteinReference
xref: Reference/UniProt P20309
organism: BiologicalState777

Interaction5067
type: MolecularInteraction
interaction type: direct_interaction
name: Pirenzepine inhibits Muscarinic acetylcholine receptor M1
participant: Pirenzepine
participant: Muscarinic acetylcholine receptor M1

Gastrin/cholecystokinin type B receptor
type: Protein
entity reference: Gastrin/cholecystokinin type B receptor
name: SubPathwayInput

Reference/HMDB HMDB0000595
type: UnificationXref
id: HMDB0000595
db: HMDB

Histamine H2 receptor
type: ProteinReference
xref: Reference/UniProt P25021
organism: BiologicalState777

ChemicalStructure/PW C008196
type: ChemicalStructure
structure format: SMILES

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Gastrin
type: Protein
cellular location: Basolateral cell membrane
entity reference: Gastrin

Reference/KEGG Compound C00388
type: UnificationXref
id: C00388
db: KEGG Compound

Reference/ChemSpider 4682
type: UnificationXref
id: 4682
db: ChemSpider

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Reference/SMPDB SMP0000751
type: UnificationXref
id: SMP0000751
db: SMPDB

Reference/ChEBI CHEBI 29103
type: UnificationXref
id: CHEBI:29103
db: ChEBI

Compound/PW C000457/Stoichiometry/1.0
type: Stoichiometry
physical entity: Potassium
stoichiometric coefficient: 1.0

Interaction3460
type: MolecularInteraction
interaction type: direct_interaction
name: Histamine activates Histamine H2 receptor
participant: Histamine H2 receptor
participant: Histamine

Reference/PubChem-compound 769
type: UnificationXref
id: 769
db: PubChem-compound

Potassium
type: SmallMolecule
entity reference: Potassium

Reference/CAS 51-45-6
type: UnificationXref
id: 51-45-6
db: CAS

Gastrin/cholecystokinin type B receptor
type: Protein
cellular location: Basolateral cell membrane
entity reference: Gastrin/cholecystokinin type B receptor

Basolateral cell membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0016323

Water
type: SmallMolecule
entity reference: Water

Carbonic anhydrase 1
type: Protein
entity reference: Carbonic anhydrase 1

Pirenzepine
type: SmallMolecule
entity reference: Pirenzepine

Reference/UniProt P51787
type: UnificationXref
id: P51787
db: UniProt

Reference/HMDB HMDB0000492
type: UnificationXref
id: HMDB0000492
db: HMDB

Reference/ChEBI CHEBI 17996
type: UnificationXref
id: CHEBI:17996
db: ChEBI

Potassium voltage-gated channel subfamily KQT member 1
type: ProteinReference
xref: Reference/UniProt P51787

Potassium voltage-gated channel subfamily E member 2
type: ProteinReference
xref: Reference/UniProt Q9Y6J6

Somatostatin receptor type 2
type: ProteinReference
xref: Reference/UniProt P30874
organism: BiologicalState777

Reference/BioCyc K+
type: UnificationXref
id: K%2b
db: BioCyc

Reference/KEGG Compound C00288
type: UnificationXref
id: C00288
db: KEGG Compound

Reference/CAS 16887-00-6
type: UnificationXref
id: 16887-00-6
db: CAS

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Reference/CAS 51-84-3
type: UnificationXref
id: 51-84-3
db: CAS

Hydrogen carbonate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Hydrogen carbonate

Homo sapiens
type: BioSource
xref: Reference/TAXONOMY 9606

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C000374 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chloride ion
stoichiometric coefficient: 1.0

4.2.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000463/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Hydrogen carbonate
right: Hydrogen Ion
spontaneous: false
EC number: 4.2.1.1
left: Water
left: Carbon dioxide
name: Carbon dioxide + Water → Hydrogen Ion + Hydrogen carbonate
conversion direction: LEFT_TO_RIGHT

Hydrogen Ion
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Hydrogen Ion

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/ChemSpider 791
type: UnificationXref
id: 791
db: ChemSpider

Compound/PW C000374/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chloride ion
stoichiometric coefficient: 1.0

Reference/UniProt P40879
type: UnificationXref
id: P40879
db: UniProt

Gastrin/cholecystokinin type B receptor
type: ProteinReference
xref: Reference/UniProt P32239
organism: BiologicalState777

Reference/UniProt P32239
type: UnificationXref
id: P32239
db: UniProt

Reference/PubChem-compound 774
type: UnificationXref
id: 774
db: PubChem-compound

TransportCatalysis2046
type: Catalysis
controller: Chloride anion exchanger
controlled: Transport10876
control type: ACTIVATION

Transport13806
type: Transport
participant stoichiometry: Compound/PW C000457 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000457/Stoichiometry/1.0
right: Potassium
spontaneous: true
left: Potassium
name: Potassium (←) Transport: Homo sapiens, Stomach to Homo sapiens, Stomach, Parietal Cell, Cytoplasm
conversion direction: REVERSIBLE

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/ChemSpider 306
type: UnificationXref
id: 306
db: ChemSpider

Reference/UniProt P25021
type: UnificationXref
id: P25021
db: UniProt

ChemicalStructure/PW C000714
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)OCC[N+](C)(C)C

Reference/UniProt Q9Y6J6
type: UnificationXref
id: Q9Y6J6
db: UniProt

Interaction3238
type: MolecularInteraction
interaction type: direct_interaction
name: Gastrin activates Gastrin/cholecystokinin type B receptor
participant: Gastrin
participant: Gastrin/cholecystokinin type B receptor

KCNE2/KCNQ1 Channel
type: Complex
component: Potassium voltage-gated channel subfamily KQT member 1
component: Potassium voltage-gated channel subfamily E member 2

Interaction2828
type: MolecularInteraction
interaction type: direct_interaction
name: Acetylcholine activates Muscarinic acetylcholine receptor M3
participant: Muscarinic acetylcholine receptor M3
participant: Acetylcholine

Reference/TAXONOMY 9606
type: UnificationXref
id: 9606
db: TAXONOMY

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Potassium
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Potassium

Reference/ChEBI CHEBI 17544
type: UnificationXref
id: CHEBI:17544
db: ChEBI

Reference/PubChem-compound 53481605
type: UnificationXref
id: 53481605
db: PubChem-compound

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/CELL TYPE ONTOLOGY CL 0000162
type: UnificationXref
id: CL:0000162
db: CELL TYPE ONTOLOGY

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Transport10881
type: Transport
participant stoichiometry: Compound/PW C000374 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000463/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000463 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000374/Stoichiometry/1.0
right: Hydrogen carbonate
right: Chloride ion
spontaneous: false
left: Hydrogen carbonate
left: Chloride ion
name: Hydrogen carbonate (→), Chloride ion (←) Transport: Homo sapiens, Stomach, Parietal Cell, Cytoplasm to Homo sapiens, Blood Vessel
conversion direction: LEFT_TO_RIGHT

Chloride ion
type: SmallMolecule
entity reference: Chloride ion

Somatostatin
type: SmallMoleculeReference
xref: Reference/PubChem-compound 53481605
xref: Reference/HMDB HMDB0013072
chemical formula: C77H106N18O19S2
molecular weight: 1650.7323
structure: ChemicalStructure/PW C008196

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

G-Protein Signaling Cascade
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway116828
pathway component: SubPathwayInteraction116828
xref: Reference/SMPDB SMP0000751
xref: Reference/PathWhiz PW000728
name: SubPathway

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

H(+)/K(+) ATPase subunit
type: Complex
component stoichiometry: Protein/1340/Stoichiometry/1.0
component stoichiometry: Protein/1354/Stoichiometry/1.0
component: Potassium-transporting ATPase subunit beta
component: Potassium-transporting ATPase alpha chain 1
name: SubPathwayOutput

Histamine H2 receptor
type: Protein
cellular location: Basolateral cell membrane
entity reference: Histamine H2 receptor

Chloride anion exchanger
type: Protein
entity reference: Chloride anion exchanger

Transport10876
type: Transport
participant stoichiometry: Compound/PW C000374 Basolateral cell membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000374 Cytoplasm/Stoichiometry/1.0
right: Chloride ion
spontaneous: false
left: Chloride ion
name: Chloride ion (→) Transport: Homo sapiens, Stomach, Parietal Cell, Cytoplasm to Homo sapiens, Stomach, Parietal Cell, Basolateral cell membrane
conversion direction: LEFT_TO_RIGHT

Carbonic anhydrase 1
type: ProteinReference
xref: Reference/UniProt P00915

Reference/BioCyc HISTAMINE
type: UnificationXref
id: HISTAMINE
db: BioCyc

Transport11168
type: Transport
participant stoichiometry: Compound/PW C040034 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000457 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000457/Stoichiometry/1.0
right: Potassium
right: Hydrogen Ion
spontaneous: false
left: Hydrogen Ion
left: Potassium
name: Potassium (→), Hydrogen Ion (←) Transport: Homo sapiens, Stomach to Homo sapiens, Stomach, Parietal Cell, Cytoplasm
conversion direction: LEFT_TO_RIGHT

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Muscarinic acetylcholine receptor M3
type: Protein
cellular location: Basolateral cell membrane
entity reference: Muscarinic acetylcholine receptor M3

Histamine
type: SmallMolecule
cellular location: Basolateral cell membrane
entity reference: Histamine

Protein/1354/Stoichiometry/1.0
type: Stoichiometry
physical entity: Potassium-transporting ATPase alpha chain 1
stoichiometric coefficient: 1.0

Reference/BRENDA TISSUE ONTOLOGY BTO 0001307
type: UnificationXref
id: BTO:0001307
db: BRENDA TISSUE ONTOLOGY

Reference/BioCyc CPD-4521
type: UnificationXref
id: CPD-4521
db: BioCyc

Reference/GENE ONTOLOGY GO 0016323
type: UnificationXref
id: GO:0016323
db: GENE ONTOLOGY

Reference/GENE ONTOLOGY GO 0016324
type: UnificationXref
id: GO:0016324
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 18295
type: UnificationXref
id: CHEBI:18295
db: ChEBI

Chloride ion
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Chloride ion

Reference/PubChem-compound 187
type: UnificationXref
id: 187
db: PubChem-compound

Interaction3726
type: MolecularInteraction
interaction type: direct_interaction
name: Somatostatin activates Somatostatin receptor type 2
participant: Somatostatin
participant: Somatostatin receptor type 2

Reference/HMDB HMDB0000870
type: UnificationXref
id: HMDB0000870
db: HMDB

Reference/ChemSpider 753
type: UnificationXref
id: 753
db: ChemSpider

Pirenzepine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 8247
xref: Reference/CAS 28797-61-7
xref: Reference/KEGG Compound C07508
xref: Reference/PubChem-compound 4848
xref: Reference/HMDB HMDB0014808
xref: Reference/ChemSpider 4682
chemical formula: C19H21N5O2
molecular weight: 351.16953
structure: ChemicalStructure/PW C009148

Potassium-transporting ATPase subunit beta
type: Protein
entity reference: Potassium-transporting ATPase subunit beta

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Histamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000870
xref: Reference/ChemSpider 753
xref: Reference/PubChem-compound 774
xref: Reference/BioCyc HISTAMINE
xref: Reference/CAS 51-45-6
xref: Reference/ChEBI CHEBI 18295
xref: Reference/KEGG Compound C00388
chemical formula: C5H9N3
molecular weight: 111.07965
structure: ChemicalStructure/PW C000693

Reference/UniProt P51164
type: UnificationXref
id: P51164
db: UniProt

Acetylcholine
type: SmallMolecule
cellular location: Basolateral cell membrane
entity reference: Acetylcholine

Reference/ChEBI CHEBI 15355
type: UnificationXref
id: CHEBI:15355
db: ChEBI

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Potassium
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00238
xref: Reference/HMDB HMDB0000586
xref: Reference/PubChem-compound 813
xref: Reference/ChemSpider 791
xref: Reference/CAS 24203-36-9
xref: Reference/BioCyc K+
xref: Reference/ChEBI CHEBI 29103
chemical formula: K
molecular weight: 38.963707
structure: ChemicalStructure/PW C000457

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/ChemSpider 749
type: UnificationXref
id: 749
db: ChemSpider

Reference/CAS 71-52-3
type: UnificationXref
id: 71-52-3
db: CAS

Reference/KEGG Compound C01996
type: UnificationXref
id: C01996
db: KEGG Compound

BiologicalState778
type: BioSource
xref: Reference/TAXONOMY 9606
name: Homo sapiens, Stomach
tissue: Stomach

BiologicalState777
type: BioSource
cell type: Parietal Cell
xref: Reference/TAXONOMY 9606
name: Homo sapiens, Stomach, Parietal Cell
tissue: Stomach

Protein/1340/Stoichiometry/1.0
type: Stoichiometry
physical entity: Potassium-transporting ATPase subunit beta
stoichiometric coefficient: 1.0

Hydrogen carbonate
type: SmallMolecule
entity reference: Hydrogen carbonate

Potassium-transporting ATPase alpha chain 1
type: Protein
entity reference: Potassium-transporting ATPase alpha chain 1

Pirenzepine M1 Ulcer Treatment Action Pathway
type: Pathway
pathway order: PathwayEnzymeReaction/2501436
pathway order: PathwayInteraction/3726
pathway order: PathwayInteraction/3238
pathway order: PathwaySubPathway/116828
pathway order: PathwayTransport/2501437
pathway order: PathwayTransport/2501432
pathway order: PathwayTransport/2501443
pathway order: PathwayInteraction/5067
pathway order: PathwayTransport/2501433
pathway order: PathwayInteraction/2828
pathway order: PathwayInteraction/3460
pathway component: TransportCatalysis4844
pathway component: Interaction3460
pathway component: TransportCatalysis2046
pathway component: Transport13806
pathway component: TransportCatalysis2311
pathway component: ReactionCatalysis1409
pathway component: Transport10876
pathway component: Transport11168
pathway component: Interaction5067
pathway component: Interaction3726
pathway component: 4.2.1.1
pathway component: Transport10881
pathway component: Interaction3238
pathway component: Interaction2828
pathway component: TransportCatalysis2051
pathway component: G-Protein Signaling Cascade
xref: Reference/PathWhiz PW126191
xref: Reference/SMPDB SMP0124706
organism: Homo sapiens

Hydrogen carbonate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000595
xref: Reference/ChEBI CHEBI 17544
xref: Reference/PubChem-compound 769
xref: Reference/BioCyc HCO3
xref: Reference/ChemSpider 749
xref: Reference/CAS 71-52-3
xref: Reference/KEGG Compound C00288
chemical formula: CH2O3
molecular weight: 62.000393
structure: ChemicalStructure/PW C000463

Chloride ion
type: SmallMolecule
cellular location: Basolateral cell membrane
entity reference: Chloride ion

Somatostatin
type: SmallMolecule
cellular location: Apical cell membrane
entity reference: Somatostatin

Reference/ChemSpider 182
type: UnificationXref
id: 182
db: ChemSpider