Prilocaine is an local anesthetic that is similar to lidocaine often used most commonly for dental procedures. Prilocaine acts by binding to the intracellular surface of the sodium channels which blocks the influx of sodium into the cell. Due to this block of sodium ions this prevents the generation and propagation of action potential. This reverses when the drug diffuses out of the cell and is excreted from the body, allowing the sodium channel to function as it normally would and continue to generate action potential. Prilocaine is metabolized by the liver and kidney and is excreted by the kidney.

Prilocaine References