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Unknown Mitogen- activated protein kinase kinase kinase 1 Mitogen- activated protein kinase kinase kinase 14 Inhibitor of nuclear factor kappa-B kinase subunit alpha Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor superfamily member 1B FAS-associated death domain protein Tumor necrosis factor receptor type 1-associated DEATH domain protein Receptor- interacting serine/threonine- protein kinase 1 TNF receptor- associated factor 6 Tumor necrosis factor Interleukin-1 receptor type 1 TNF receptor- associated factor 6 Myeloid differentiation primary response protein MyD88 Interleukin-1 receptor- associated kinase 1 Interleukin-1 alpha TGF-beta- activated kinase 1 and MAP3K7-binding protein 1 Mitogen- activated protein kinase kinase kinase 7 Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit alpha Nuclear factor NF-kappa-B p105 subunit NF-kappa-B inhibitor alpha Transcription factor p65 Nuclear factor NF-kappa-B p105 subunit NF-kappa-B inhibitor alpha Transcription factor p65 Polyubiquitin-C Transcription factor p65 Nuclear factor NF-kappa-B p105 subunit NF-kappa-B inhibitor alpha Transcription factor p65 Nuclear factor NF-kappa-B p105 subunit Transcription factor p65 Tumor necrosis factor Interleukin-1 alpha Nuclear receptor coactivator 3 Calcium/calmodulin- dependent protein kinase kinase 1 Calcium/calmodulin- dependent protein kinase kinase 2 NF-kappa-B inhibitor alpha NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Transcription factor p65 Transcription factor p65 Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65 Polyubiquitin-C Nuclear factor NF-kappa-B p105 subunit Interleukin-1 receptor- associated kinase 1 Myeloid differentiation primary response protein MyD88 TNF receptor- associated factor 6 Toll-like receptor 4 Phosphate Phosphate Phosphate Phosphate Phosphate Phosphate lipopolysaccharide Other Signals UV Extracellular Cytoplasm Nucleus