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Malate dehydrogenase, mitochondrial Methylcytosine dioxygenase TET1 Lysine-specific demethylase 2A Mitochondrial pyruvate carrier 1 Pyruvate dehydrogenase complex Citrate synthase, mitochondrial Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial Oxoglutarate dehydrogenase complex Succinyl-CoA ligase Fumarate hydratase, mitochondrial Pyruvate carboxylase, mitochondrial Succinate dehydrogenase Aconitate hydratase, mitochondrial Aconitate hydratase, mitochondrial NADP-specific glutamate dehydrogenase Glutaminase liver isoform, mitochondrial Isocitrate dehydrogenase [NADP] cytoplasmic NADP+-specific isocitrate dehydrogenase mutant Isocitrate dehydrogenase 2 [NADP], mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial Cytoplasmic aconitate hydratase Pyruvic acid FADH2 Pyruvic acid CoA NAD Acetyl-CoA CO2 NADH H2O Oxalacetic acid Citric acid CoA Isocitric acid NAD Oxoglutaric acid CO2 NADH H+ NAD CoA Succinyl-CoA NADH H+ CO2 Pi GDP Succinic acid CoA GTP L-Malic acid Fumaric acid H2O NAD NADH H+ ATP HCO3- ADP Pi Q FAD QH2 cis-Aconitic acid H2O H2O NADPH Ammonium H+ L-Glutamic acid H2O NADP L-Glutamine H2O NH3 Isocitric acid NADP Oxoglutaric acid NADPH NADPH 2-Hydroxyglutarate NADP NADP Oxoglutaric acid NADPH NADP NADPH Citric acid Thiamine pyrophosphate Lipoamide FAD Magnesium Thiamine pyrophosphate Lipoamide FAD Biotin Manganese 4Fe-4S 4Fe-4S Magnesium 4Fe-4S Glycolysis Mitochondrial Electron Transport Chain Inner mitochondrial membrane Mitochondrial intermembrane space Cytosol Mitochondrial matrix Mitochondrion Intracellular Space Inner mitochondrial membrane Outer mitochondrial membrane Cytosol Epigenetic Regulation Oncogene Activation, Tumour-suppressor inactivation TCA cycle Citric acid Isocitric acid Oxoglutaric acid 2-Hydroxyglutarate Cytoplasmic aconitate hydratase Isocitrate dehydrogenase [NADP] cytoplasmic mutIDH1 Methylcystosine dioxygenase TET1 Lysine-specific demethylase 2A