Caspofungin is an echinocandin antifungal drug used to treat a variety of fungal infections. It is known as the brand Cancidas. It is used for the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.It works by inhibiting cell wall synthesis. Caspofungin inhibits glucan synthase, an enzyme present in fungal, but not mammalian cells. This prevents the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, which ultimately leads to osmotic instability and cell death.

Caspofungin Pathway References