Acceptor + Prostaglandin H2 + Water ← Prostaglandin G2 + Reduced acceptor
Loxoprofen → Loxoprofen trans-OH metabolite
Loxoprofen trans-OH metabolite (→) Transport: Homo sapiens, Blood Vessel to Homo sapiens, Cell, Cytosol
Loxoprofen trans-OH metabolite (→) Transport: Homo sapiens, Liver, Hepatocyte, Endoplasmic Reticulum Membrane to Homo sapiens, Blood Vessel
Loxoprofen (→) Transport: Homo sapiens to Homo sapiens, Liver, Hepatocyte, Endoplasmic Reticulum Membrane
Prostaglandin H2 → Prostaglandin I2
Prostaglandin H2 → Prostaglandin E2
Arachidonic acid + 2 Oxygen → Prostaglandin G2
Loxoprofen trans-OH metabolite inhibits Prostaglandin G/H synthase 2
Loxoprofen trans-OH metabolite inhibits Prostaglandin G/H synthase 1