Reference/CAS 57576-52-0
type: UnificationXref
id: 57576-52-0
db: CAS

Compound/PW C000821 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Arachidonic acid
stoichiometric coefficient: 1.0

Reference/BioCyc PROSTAGLANDIN-H2
type: UnificationXref
id: PROSTAGLANDIN-H2
db: BioCyc

Arachidonic acid
type: SmallMoleculeReference
xref: Reference/CAS 506-32-1
xref: Reference/BioCyc ARACHIDONIC ACID
xref: Reference/ChEBI CHEBI 15843
xref: Reference/KEGG Compound C00219
xref: Reference/HMDB HMDB0001043
xref: Reference/ChemSpider 392692
xref: Reference/PubChem-compound 444899
chemical formula: C20H32O2
molecular weight: 304.24023
structure: ChemicalStructure/PW C000821

Reference/ChEBI CHEBI 15843
type: UnificationXref
id: CHEBI:15843
db: ChEBI

Thromboxane A2
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Thromboxane A2

Endoplasmic Reticulum Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005789

Reference/PubChem-compound 445049
type: UnificationXref
id: 445049
db: PubChem-compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 5280360
type: UnificationXref
id: 5280360
db: PubChem-compound

Phenylbutazone Action Pathway (New)
type: Pathway
pathway order: PathwayTransport/2533033
pathway order: PathwayEnzymeReaction/2533000
pathway order: PathwayEnzymeReaction/2533003
pathway order: PathwayEnzymeReaction/2533004
pathway order: PathwayEnzymeReaction/2533001
pathway order: PathwayInteraction/3638
pathway order: PathwayEnzymeReaction/2533002
pathway order: PathwayInteraction/3637
pathway order: PathwayInteraction/4902
pathway order: PathwayEnzymeReaction/2533005
pathway order: PathwayEnzymeReaction/2532999
pathway order: PathwayEnzymeReaction/2532998
pathway order: PathwayTransport/2533035
pathway component: ReactionCatalysis188
pathway component: ReactionCatalysis202959
pathway component: TransportCatalysis5832
pathway component: ReactionCatalysis187
pathway component: Reaction212945
pathway component: ReactionCatalysis202577
pathway component: Reaction213363
pathway component: ReactionCatalysis73
pathway component: ReactionCatalysis202578
pathway component: Transport15647
pathway component: ReactionCatalysis77
pathway component: Transport15646
pathway component: 5.3.99.4
pathway component: Interaction3638
pathway component: 5.3.99.3
pathway component: Interaction4902
pathway component: Interaction3637
pathway component: 5.3.99.5
pathway component: ReactionCatalysis738
pathway component: 1.14.99.1
xref: Reference/PathWhiz PW128145
xref: Reference/SMPDB SMP0126545
organism: Homo sapiens

Prostaglandin E2
type: SmallMoleculeReference
xref: Reference/CAS 363-24-6
xref: Reference/ChemSpider 4444059
xref: Reference/KEGG Compound C00584
xref: Reference/BioCyc 5Z13E-15S-1115-DIHYDROXY-9-OXOPROS
xref: Reference/PubChem-compound 5280360
xref: Reference/ChEBI CHEBI 15551
xref: Reference/HMDB HMDB0001220
chemical formula: C20H32O5
molecular weight: 352.22498
structure: ChemicalStructure/PW C000949

ChemicalStructure/PW C001814
type: ChemicalStructure
structure format: SMILES

direct_interaction
type: InteractionVocabulary

Thromboxane A2
type: SmallMoleculeReference
xref: Reference/CAS 57576-52-0
xref: Reference/PubChem-compound 5280497
xref: Reference/ChemSpider 4444137
xref: Reference/BioCyc ALPHA11-ALPHA-EPOXY-15-HYDROXYTHROMBA
xref: Reference/ChEBI CHEBI 15627
xref: Reference/KEGG Compound C02198
xref: Reference/HMDB HMDB0001452
chemical formula: C20H32O5
molecular weight: 352.22498
structure: ChemicalStructure/PW C001121

Reference/PubChem-compound 5280883
type: UnificationXref
id: 5280883
db: PubChem-compound

Cytosolic phospholipase A2
type: Protein
cellular location: Cytosol
entity reference: Cytosolic phospholipase A2

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Unknown
type: ProteinReference

Compound/Generic40 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Reduced acceptor
stoichiometric coefficient: 1.0

Reference/ChemSpider 392692
type: UnificationXref
id: 392692
db: ChemSpider

Reference/HMDB HMDB0001220
type: UnificationXref
id: HMDB0001220
db: HMDB

Prostaglandin G/H synthase 1
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Prostaglandin G/H synthase 1

Prostaglandin E synthase
type: ProteinReference
xref: Reference/UniProt O14684
organism: Homo sapiens

Reaction212945
type: BiochemicalReaction
participant stoichiometry: Compound/Generic41 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001814 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001068 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic40 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Prostaglandin G2
right: Reduced acceptor
spontaneous: false
left: Water
left: Acceptor
left: Prostaglandin H2
name: Acceptor + Prostaglandin H2 + Water ← Prostaglandin G2 + Reduced acceptor
conversion direction: RIGHT_TO_LEFT

Reference/ChEBI CHEBI 15339
type: UnificationXref
id: CHEBI:15339
db: ChEBI

Reduced acceptor
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Reduced acceptor

ChemicalStructure/PW C001028
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5282411
type: UnificationXref
id: 5282411
db: PubChem-compound

Reference/UniProt P24557
type: UnificationXref
id: P24557
db: UniProt

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Phenylbutazone
type: SmallMolecule
cellular location: Cytosol
entity reference: Phenylbutazone

Compound/Generic617 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phospholipids
stoichiometric coefficient: 1.0

ChemicalStructure/PW C009276
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0014950
type: UnificationXref
id: HMDB0014950
db: HMDB

ChemicalStructure/PW C000949
type: ChemicalStructure
structure format: SMILES

Thromboxane-A synthase
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Thromboxane-A synthase

Reference/PubChem-compound 4781
type: UnificationXref
id: 4781
db: PubChem-compound

Reference/ChemSpider 4444137
type: UnificationXref
id: 4444137
db: ChemSpider

Reference/CAS 50-33-9
type: UnificationXref
id: 50-33-9
db: CAS

Reference/KEGG Compound C00219
type: UnificationXref
id: C00219
db: KEGG Compound

Homo sapiens
type: BioSource
xref: Reference/TAXONOMY 9606

ChemicalStructure/PW C000821
type: ChemicalStructure
structure format: SMILES
structure data: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O

ReactionCatalysis202577
type: Catalysis
controller: Prostaglandin G/H synthase 1
controlled: Reaction212945
control type: ACTIVATION

Reaction213363
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000821 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/Generic617 Cytosol/Stoichiometry/1.0
right: Arachidonic acid
spontaneous: false
left: Phospholipids
name: Phospholipids → Arachidonic acid
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis202578
type: Catalysis
controller: Prostaglandin G/H synthase 2
controlled: Reaction212945
control type: ACTIVATION

Reference/KEGG Compound C02198
type: UnificationXref
id: C02198
db: KEGG Compound

Acceptor
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15339

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reduced acceptor
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15022

Compound/PW C001420 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15022
type: UnificationXref
id: CHEBI:15022
db: ChEBI

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

Water
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Water

ChemicalStructure/PW C001121
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

Prostaglandin H2
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00427
xref: Reference/ChEBI CHEBI 15554
xref: Reference/CAS 42935-17-1
xref: Reference/BioCyc PROSTAGLANDIN-H2
xref: Reference/ChemSpider 392800
xref: Reference/PubChem-compound 445049
xref: Reference/HMDB HMDB0001381
chemical formula: C20H32O5
molecular weight: 352.22498
structure: ChemicalStructure/PW C001068

Prostacyclin synthase
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Prostacyclin synthase

Reference/GENE ONTOLOGY GO 0005789
type: UnificationXref
id: GO:0005789
db: GENE ONTOLOGY

5.3.99.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001068 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001121 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Thromboxane A2
spontaneous: false
EC number: 5.3.99.5
left: Prostaglandin H2
name: Prostaglandin H2 → Thromboxane A2
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P35354
type: UnificationXref
id: P35354
db: UniProt

Reference/UniProt Q16647
type: UnificationXref
id: Q16647
db: UniProt

Compound/PW C000949 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prostaglandin E2
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15552
type: UnificationXref
id: CHEBI:15552
db: ChEBI

Reference/ChEBI CHEBI 15554
type: UnificationXref
id: CHEBI:15554
db: ChEBI

TransportCatalysis5832
type: Catalysis
controller: Unknown
controlled: Transport15647
control type: ACTIVATION

Reference/KEGG Compound C00584
type: UnificationXref
id: C00584
db: KEGG Compound

Compound/PW C009276 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phenylbutazone
stoichiometric coefficient: 1.0

Prostacyclin synthase
type: ProteinReference
xref: Reference/UniProt Q16647
organism: Homo sapiens

Compound/PW C001121 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thromboxane A2
stoichiometric coefficient: 1.0

Reference/UniProt O14684
type: UnificationXref
id: O14684
db: UniProt

Reference/ChEBI CHEBI 15551
type: UnificationXref
id: CHEBI:15551
db: ChEBI

Reference/KEGG Compound C01312
type: UnificationXref
id: C01312
db: KEGG Compound

Cytosolic phospholipase A2
type: ProteinReference
xref: Reference/UniProt P47712
organism: Homo sapiens

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Reference/CAS 363-24-6
type: UnificationXref
id: 363-24-6
db: CAS

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

Interaction3638
type: MolecularInteraction
interaction type: direct_interaction
name: Phenylbutazone inhibits Prostaglandin G/H synthase 2
participant: Prostaglandin G/H synthase 2
participant: Phenylbutazone

Reference/BioCyc 5Z13E-15S-69-ALPHA-EPOXY-11-ALPHA
type: UnificationXref
id: 5Z13E-15S-69-ALPHA-EPOXY-11-ALPHA
db: BioCyc

Reference/PubChem-compound 5280497
type: UnificationXref
id: 5280497
db: PubChem-compound

Reference/ChEBI CHEBI 27647
type: UnificationXref
id: CHEBI:27647
db: ChEBI

Prostaglandin H2
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Prostaglandin H2

Reference/UniProt P47712
type: UnificationXref
id: P47712
db: UniProt

Interaction3637
type: MolecularInteraction
interaction type: direct_interaction
name: Phenylbutazone inhibits Prostaglandin G/H synthase 1
participant: Prostaglandin G/H synthase 1
participant: Phenylbutazone

Compound/PW C000821 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Arachidonic acid
stoichiometric coefficient: 1.0

Phenylbutazone
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Phenylbutazone

Reference/ChemSpider 4444406
type: UnificationXref
id: 4444406
db: ChemSpider

Reference/TAXONOMY 9606
type: UnificationXref
id: 9606
db: TAXONOMY

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChemSpider 4445566
type: UnificationXref
id: 4445566
db: ChemSpider

Compound/PW C009276/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phenylbutazone
stoichiometric coefficient: 1.0

ReactionCatalysis202959
type: Catalysis
controller: Cytosolic phospholipase A2
controlled: Reaction213363
control type: ACTIVATION

Acceptor
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Acceptor

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Prostaglandin E synthase
type: Complex
component stoichiometry: Protein/76 Cytoplasm/Stoichiometry/3.0
cellular location: Cytoplasm
component: Prostaglandin E synthase

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

Phospholipids
type: SmallMoleculeReference

Compound/PW C001065 Endoplasmic Reticulum Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 2.0

Prostaglandin E2
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Prostaglandin E2

Thromboxane-A synthase
type: ProteinReference
xref: Reference/UniProt P24557
organism: Homo sapiens

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

Reference/CAS 42935-17-1
type: UnificationXref
id: 42935-17-1
db: CAS

Prostaglandin E synthase
type: Protein
cellular location: Cytoplasm
entity reference: Prostaglandin E synthase

ChemicalStructure/PW C001068
type: ChemicalStructure
structure format: SMILES

Reference/CAS 51982-36-6
type: UnificationXref
id: 51982-36-6
db: CAS

Reference/BioCyc 5Z13E-15S-1115-DIHYDROXY-9-OXOPROS
type: UnificationXref
id: 5Z13E-15S-1115-DIHYDROXY-9-OXOPROS
db: BioCyc

Reference/HMDB HMDB0001381
type: UnificationXref
id: HMDB0001381
db: HMDB

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 48574
type: UnificationXref
id: CHEBI:48574
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Unknown
type: Protein
entity reference: Unknown

ReactionCatalysis188
type: Catalysis
controller: Prostaglandin E synthase
controlled: 5.3.99.3
control type: ACTIVATION

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

Oxygen
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Oxygen

Compound/Generic41 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acceptor
stoichiometric coefficient: 1.0

ReactionCatalysis187
type: Catalysis
controller: Prostacyclin synthase
controlled: 5.3.99.4
control type: ACTIVATION

Prostaglandin G/H synthase 2
type: Protein
cellular location: Endoplasmic Reticulum Membrane
entity reference: Prostaglandin G/H synthase 2

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Protein/76 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: Prostaglandin E synthase
stoichiometric coefficient: 3.0

Prostaglandin G/H synthase 1
type: ProteinReference
xref: Reference/UniProt P23219
organism: Homo sapiens

Prostaglandin G/H synthase 2
type: ProteinReference
xref: Reference/UniProt P35354
organism: Homo sapiens

Transport15647
type: Transport
participant stoichiometry: Compound/PW C009276/Stoichiometry/1.0
participant stoichiometry: Compound/PW C009276 Cytosol/Stoichiometry/1.0
right: Phenylbutazone
spontaneous: false
left: Phenylbutazone
name: Phenylbutazone (→) Transport: Homo sapiens, Blood Vessel to Homo sapiens, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport15646
type: Transport
participant stoichiometry: Compound/PW C009276/Stoichiometry/1.0
right: Phenylbutazone
spontaneous: true
left: Phenylbutazone
name: Phenylbutazone (→) Transport: Homo sapiens, Intestine to Homo sapiens, Blood Vessel
conversion direction: REVERSIBLE

Compound/PW C001028 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prostaglandin I2
stoichiometric coefficient: 1.0

Reference/KEGG Compound C07440
type: UnificationXref
id: C07440
db: KEGG Compound

Interaction4902
type: MolecularInteraction
interaction type: direct_interaction
name: Phenylbutazone inhibits Prostacyclin synthase
participant: Prostacyclin synthase
participant: Phenylbutazone

ReactionCatalysis738
type: Catalysis
controller: Prostaglandin G/H synthase 2
controlled: 1.14.99.1
control type: ACTIVATION

Arachidonic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Arachidonic acid

Reference/ChemSpider 4617
type: UnificationXref
id: 4617
db: ChemSpider

Protein/914 Endoplasmic Reticulum Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Prostaglandin G/H synthase 1
stoichiometric coefficient: 2.0

Reference/PathWhiz PW128145
type: UnificationXref
id: PW128145
db: PathWhiz

Reference/SMPDB SMP0126545
type: UnificationXref
id: SMP0126545
db: SMPDB

Reference/ChemSpider 4444059
type: UnificationXref
id: 4444059
db: ChemSpider

Prostaglandin I2
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Prostaglandin I2

ReactionCatalysis73
type: Catalysis
controller: Prostaglandin G/H synthase 1
controlled: 1.14.99.1
control type: ACTIVATION

Reference/PubChem-compound 444899
type: UnificationXref
id: 444899
db: PubChem-compound

Prostaglandin G2
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003235
xref: Reference/PubChem-compound 5280883
xref: Reference/ChEBI CHEBI 27647
xref: Reference/CAS 51982-36-6
xref: Reference/KEGG Compound C05956
xref: Reference/ChemSpider 4444406
chemical formula: C20H32O6
molecular weight: 368.21988
structure: ChemicalStructure/PW C001814

ReactionCatalysis77
type: Catalysis
controller: Thromboxane-A synthase
controlled: 5.3.99.5
control type: ACTIVATION

5.3.99.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001028 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001068 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
right: Prostaglandin I2
spontaneous: false
EC number: 5.3.99.4
left: Prostaglandin H2
name: Prostaglandin H2 → Prostaglandin I2
conversion direction: LEFT_TO_RIGHT

5.3.99.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000949 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001068 Cytoplasm/Stoichiometry/1.0
right: Prostaglandin E2
spontaneous: false
EC number: 5.3.99.3
left: Prostaglandin H2
name: Prostaglandin H2 → Prostaglandin E2
conversion direction: LEFT_TO_RIGHT

Reference/UniProt P23219
type: UnificationXref
id: P23219
db: UniProt

Prostaglandin H2
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Prostaglandin H2

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

1.14.99.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000821 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001814 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065 Endoplasmic Reticulum Membrane/Stoichiometry/2.0
right: Prostaglandin G2
spontaneous: false
EC number: 1.14.99.1
left: Oxygen
left: Arachidonic acid
name: Arachidonic acid + 2 Oxygen → Prostaglandin G2
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0001043
type: UnificationXref
id: HMDB0001043
db: HMDB

Reference/CAS 35121-78-9
type: UnificationXref
id: 35121-78-9
db: CAS

Reference/KEGG Compound C00427
type: UnificationXref
id: C00427
db: KEGG Compound

Reference/CAS 506-32-1
type: UnificationXref
id: 506-32-1
db: CAS

Prostaglandin G2
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Prostaglandin G2

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

Reference/ChemSpider 392800
type: UnificationXref
id: 392800
db: ChemSpider

Compound/PW C001068 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prostaglandin H2
stoichiometric coefficient: 1.0

Compound/PW C001068 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prostaglandin H2
stoichiometric coefficient: 1.0

Prostaglandin I2
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15552
xref: Reference/ChemSpider 4445566
xref: Reference/HMDB HMDB0001335
xref: Reference/BioCyc 5Z13E-15S-69-ALPHA-EPOXY-11-ALPHA
xref: Reference/PubChem-compound 5282411
xref: Reference/CAS 35121-78-9
xref: Reference/KEGG Compound C01312
chemical formula: C20H32O5
molecular weight: 352.22498
structure: ChemicalStructure/PW C001028

Reference/KEGG Compound C05956
type: UnificationXref
id: C05956
db: KEGG Compound

Phospholipids
type: SmallMolecule
cellular location: Cytosol
entity reference: Phospholipids

Reference/HMDB HMDB0001335
type: UnificationXref
id: HMDB0001335
db: HMDB

Reference/HMDB HMDB0003235
type: UnificationXref
id: HMDB0003235
db: HMDB

Reference/BioCyc ARACHIDONIC ACID
type: UnificationXref
id: ARACHIDONIC_ACID
db: BioCyc

Arachidonic acid
type: SmallMolecule
cellular location: Endoplasmic Reticulum Membrane
entity reference: Arachidonic acid

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Compound/PW C001814 Endoplasmic Reticulum Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prostaglandin G2
stoichiometric coefficient: 1.0

Reference/BioCyc ALPHA11-ALPHA-EPOXY-15-HYDROXYTHROMBA
type: UnificationXref
id: ALPHA11-ALPHA-EPOXY-15-HYDROXYTHROMBA
db: BioCyc

Reference/ChEBI CHEBI 15627
type: UnificationXref
id: CHEBI:15627
db: ChEBI

Prostaglandin G/H synthase 1
type: Complex
component stoichiometry: Protein/914 Endoplasmic Reticulum Membrane/Stoichiometry/2.0
cellular location: Endoplasmic Reticulum Membrane
component: Prostaglandin G/H synthase 1

Phenylbutazone
type: SmallMolecule
entity reference: Phenylbutazone

Reference/HMDB HMDB0001452
type: UnificationXref
id: HMDB0001452
db: HMDB

Phenylbutazone
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0014950
xref: Reference/PubChem-compound 4781
xref: Reference/ChemSpider 4617
xref: Reference/CAS 50-33-9
xref: Reference/KEGG Compound C07440
xref: Reference/ChEBI CHEBI 48574
chemical formula: C19H20N2O2
molecular weight: 308.15247
structure: ChemicalStructure/PW C009276