Sulfameter, also known as sulfamethoxydiazine, is a long-acting antibacterial from the sulfonamide drug class. This drug is indicated in the treatment of leprosy, and urinary, and respiratory tract infections. It shows bacteriostatic effects against gram-positive and gram-negative bacteria. Sulfameter is a competitive inhibitor of the enzyme dihydropteroate synthase. This enzyme does the condensation of para-aminobenzoic acid (PABA) to produce folic acids. Without the synthesis of folate, the bacteria can not grow (bacteriostatic). Sulfameter is given orally as a tablet.

Sulfameter Pathway References