Steroid 17-alpha-hydroxylase/17,20 lyase
Oxygen + Progesterone + Reduced acceptor → 17-Hydroxyprogesterone + Acceptor + Water
Oxygen + Pregnenolone + Reduced acceptor → 17a-Hydroxypregnenolone + Acceptor + Water
3 beta-hydroxysteroid dehydrogenase type 5
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Guanine nucleotide-binding protein G(i) subunit alpha-1
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
PIP2(16:0/16:2(9Z,12Z)) + Water → 1,2-Diacyl-sn-glycerol (dioctadecanoyl, n-C18:0) + Inositol 1,4,5-trisphosphate
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Dehydroepiandrosterone → 5-Androstenediol
17a-Hydroxypregnenolone → 17-Hydroxyprogesterone
cAMP-dependent protein kinase catalytic subunit beta
cAMP-dependent protein kinase type II-alpha regulatory subunit
Rattus norvegicus, Ovary, Granulosa Cell
Lutropin-choriogonadotropic hormone receptor
Early growth response protein 1 activates ATF3
1,2-Diacyl-sn-glycerol (dioctadecanoyl, n-C18:0)
cAMP-dependent protein kinase type I-alpha regulatory subunit
cAMP-dependent protein kinase catalytic subunit alpha
Luteinizing Hormone activates Lutropin-choriogonadotropic hormone receptor
Lutropin-choriogonadotropic hormone receptor activates G protein complex
Follicle Stimulating Hormone activates Follicle-stimulating hormone receptor bound to G protein complex
Inhibin A inhibits Follicle Stimulating Hormone
Protein kinase A activates Cytochrome P450 19A1
cAMP activates Protein kinase A catalytic subunit
G protein complex activates Adenylate cyclase type 1
Cholesterol side-chain cleavage enzyme, mitochondrial
Protein kinase A catalytic subunit activates StAR
Follicle-stimulating hormone receptor bound to G protein complex activates Adenylate cyclase type 1
PIP2(16:0/16:2(9Z,12Z)) + Potassium → Potassium
cAMP-dependent protein kinase type I-beta regulatory subunit
cAMP-dependent protein kinase type II-beta regulatory subunit
Membrane-associated progesterone receptor component 1 inhibits Progonadoliberin-1
Progesterone activates Membrane-associated progesterone receptor component 1
Adenosine triphosphate → Pyrophosphate + cAMP
Inositol 1,4,5-trisphosphate activates Calcium
17-Hydroxyprogesterone → Androstenedione
17a-Hydroxypregnenolone → Dehydroepiandrosterone
Dehydroepiandrosterone + NAD → Androstenedione + Hydrogen Ion + NADH
Follicle-stimulating hormone receptor bound to G protein complex
NAD + Testosterone ↔ Androstenedione + Hydrogen Ion + NADH
Cholesterol (→) Transport: Rattus norvegicus, Ovary, Theca Cell, Mitochondrial Outer Membrane to Rattus norvegicus, Ovary, Theca Cell, Mitochondrial Inner Membrane
Testosterone (→) Transport: Rattus norvegicus, Ovary, Theca Cell to Rattus norvegicus, Ovary, Granulosa Cell
Androstenedione (→) Transport: Rattus norvegicus, Ovary, Theca Cell to Rattus norvegicus, Ovary, Granulosa Cell
NAD + Pregnenolone → Hydrogen Ion + NADH + Progesterone