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Cytochrome P450 3A4 Butalbital Butalbital Butalbital PIS1M1 Butalbital PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Butalbital undergoes metabolism to give Butalbital PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Butalbital Butalbital Butalbital PIS1M1 Butalbital PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Butalbi Butalbi But PIS But PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Butalbital undergoes metabolism to give Butalbital PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Butalbi Butalbi But PIS But PIS U E a B