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Cytochrome P450 3A4 Cefradine Cefradine Cefradine PIS1M1 Cefradine PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Cefradine undergoes metabolism to give Cefradine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Cefradine Cefradine Cefradine PIS1M1 Cefradine PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Ced Ced Cef PIS Cef PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Cefradine undergoes metabolism to give Cefradine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Ced Ced Cef PIS Cef PIS U E a B