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Cytochrome P450 3A4 Ceftobiprole Ceftobiprole Ceftobiprole PIS1M1 Ceftobiprole PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Ceftobiprole undergoes metabolism to give Ceftobiprole PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Ceftobiprole Ceftobiprole Ceftobiprole PIS1M1 Ceftobiprole PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Cefto Cefto Cef PIS Cef PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Ceftobiprole undergoes metabolism to give Ceftobiprole PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Cefto Cefto Cef PIS Cef PIS U E a B