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Cytochrome P450 3A4 Clofibrate Clofibrate Clofibrate PIS1M1 Clofibrate PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Clofibrate undergoes metabolism to give Clofibrate PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Clofibrate Clofibrate Clofibrate PIS1M1 Clofibrate PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Epib Epib Clo PIS Clo PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Clofibrate undergoes metabolism to give Clofibrate PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Epib Epib Clo PIS Clo PIS U E a B