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Cytochrome P450 3A4 Ioversol Ioversol Ioversol PIS1M1 Ioversol PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Ioversol undergoes metabolism to give Ioversol PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Ioversol Ioversol Ioversol PIS1M1 Ioversol PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Iover Iover Iov PIS Iov PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Ioversol undergoes metabolism to give Ioversol PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Iover Iover Iov PIS Iov PIS U E a B